Published in J Immunol on July 01, 1991
The I domain is a major recognition site on the leukocyte integrin Mac-1 (CD11b/CD18) for four distinct adhesion ligands. J Cell Biol (1993) 2.87
PU.1 regulates both cytokine-dependent proliferation and differentiation of granulocyte/macrophage progenitors. EMBO J (1998) 1.84
Aberrant integrin expression during epidermal wound healing and in psoriatic epidermis. J Clin Invest (1992) 1.58
A polygenic mouse model of psoriasiform skin disease in CD18-deficient mice. Proc Natl Acad Sci U S A (1996) 1.14
The intracellular bacterium Rhodococcus equi requires Mac-1 to bind to mammalian cells. Infect Immun (1993) 1.11
Leishmania major-human macrophage interactions: cooperation between Mac-1 (CD11b/CD18) and complement receptor type 1 (CD35) in promastigote adhesion. Infect Immun (1996) 1.03
Shifts in the concentrations of magnesium and calcium in early porcine and rat wound fluids activate the cell migratory response. J Clin Invest (1995) 0.98
Aggregatibacter actinomycetemcomitans leukotoxin requires beta-sheets 1 and 2 of the human CD11a beta-propeller for cytotoxicity. Cell Microbiol (2007) 0.89
The CD11a partner in Sus scrofa lymphocyte function-associated antigen-1 (LFA-1): mRNA cloning, structure analysis and comparison with mammalian homologues. BMC Vet Res (2005) 0.81
The wild boar (Sus scrofa) lymphocyte function-associated antigen-1 (CD11a/CD18) receptor: cDNA sequencing, structure analysis and comparison with homologues. BMC Vet Res (2007) 0.77
Staphylococcal enterotoxin B-specific adhesion of murine splenic T cells to a human endothelial cell line. Immunology (1996) 0.76
Molecular characterisation of the caprine (Capra hircus) lymphocyte function-associated antigen-1 alpha subunit-encoding cDNA. BMC Vet Res (2005) 0.76
Leukocytes roll on a selectin at physiologic flow rates: distinction from and prerequisite for adhesion through integrins. Cell (1991) 11.89
The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry. Nature (1996) 11.21
Induction by IL 1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1). J Immunol (1986) 10.92
Purified intercellular adhesion molecule-1 (ICAM-1) is a ligand for lymphocyte function-associated antigen 1 (LFA-1). Cell (1987) 9.41
T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1. Nature (1989) 9.29
The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes. Proc Natl Acad Sci U S A (1997) 8.27
Overlapping patterns of activation of human endothelial cells by interleukin 1, tumor necrosis factor, and immune interferon. J Immunol (1986) 8.22
A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1) J Exp Med (1996) 7.97
A human intercellular adhesion molecule (ICAM-1) distinct from LFA-1. J Immunol (1986) 7.71
Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice. Proc Natl Acad Sci U S A (1998) 7.69
Lifetime of the P-selectin-carbohydrate bond and its response to tensile force in hydrodynamic flow. Nature (1995) 7.26
Three distinct antigens associated with human T-lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3. Proc Natl Acad Sci U S A (1982) 7.16
The lymphocyte function-associated LFA-1, CD2, and LFA-3 molecules: cell adhesion receptors of the immune system. Annu Rev Immunol (1987) 6.94
Monocyte chemoattractant protein 1 acts as a T-lymphocyte chemoattractant. Proc Natl Acad Sci U S A (1994) 6.65
Anti-Mac-1 selectively inhibits the mouse and human type three complement receptor. J Exp Med (1982) 6.56
Leukocyte adhesion deficiency: an inherited defect in the Mac-1, LFA-1, and p150,95 glycoproteins. Annu Rev Med (1987) 6.45
A cell adhesion molecule, ICAM-1, is the major surface receptor for rhinoviruses. Cell (1989) 6.37
A shared alloantigenic determinant on Ia antigens encoded by the I-A and I-E subregions: evidence for I region gene duplication. J Immunol (1981) 5.85
Primary structure of ICAM-1 demonstrates interaction between members of the immunoglobulin and integrin supergene families. Cell (1988) 5.75
Lymphocyte function-associated antigen-1 (LFA-1) interaction with intercellular adhesion molecule-1 (ICAM-1) is one of at least three mechanisms for lymphocyte adhesion to cultured endothelial cells. J Cell Biol (1988) 5.68
The arrangement of the immunoglobulin-like domains of ICAM-1 and the binding sites for LFA-1 and rhinovirus. Cell (1990) 4.83
Cloning of the beta subunit of the leukocyte adhesion proteins: homology to an extracellular matrix receptor defines a novel supergene family. Cell (1987) 4.70
ICAM-1 (CD54): a counter-receptor for Mac-1 (CD11b/CD18). J Cell Biol (1990) 4.39
Effector differentiation is not prerequisite for generation of memory cytotoxic T lymphocytes. J Clin Invest (2001) 4.37
The kinetics of L-selectin tethers and the mechanics of selectin-mediated rolling. J Cell Biol (1997) 4.34
The chemokine receptor CXCR4 is required for the retention of B lineage and granulocytic precursors within the bone marrow microenvironment. Immunity (1999) 4.24
Adhesion through L-selectin requires a threshold hydrodynamic shear. Nature (1996) 4.19
The functional significance, distribution, and structure of LFA-1, LFA-2, and LFA-3: cell surface antigens associated with CTL-target interactions. J Immunol (1983) 4.17
Binding of the integrin Mac-1 (CD11b/CD18) to the third immunoglobulin-like domain of ICAM-1 (CD54) and its regulation by glycosylation. Cell (1991) 4.15
Functional cloning of ICAM-2, a cell adhesion ligand for LFA-1 homologous to ICAM-1. Nature (1989) 3.94
The integrin VLA-4 supports tethering and rolling in flow on VCAM-1. J Cell Biol (1995) 3.88
The requirement for lymphocyte function-associated antigen 1 in homotypic leukocyte adhesion stimulated by phorbol ester. J Exp Med (1986) 3.86
Intercellular adhesion molecule-1-deficient mice are protected against ischemic renal injury. J Clin Invest (1996) 3.73
Structure and function of leukocyte integrins. Immunol Rev (1990) 3.62
Stimulated mobilization of monocyte Mac-1 and p150,95 adhesion proteins from an intracellular vesicular compartment to the cell surface. J Clin Invest (1987) 3.40
Contributions of the Mac-1 glycoprotein family to adherence-dependent granulocyte functions: structure-function assessments employing subunit-specific monoclonal antibodies. J Immunol (1986) 3.35
Leukocytosis and resistance to septic shock in intercellular adhesion molecule 1-deficient mice. J Exp Med (1994) 3.32
Glycoproteins of 210,000 and 130,000 m.w. on activated T cells: cell distribution and antigenic relation to components on resting cells and T cell lines. J Immunol (1984) 3.26
Two antigen-independent adhesion pathways used by human cytotoxic T-cell clones. Nature (1986) 3.24
The leukocyte integrins. Adv Immunol (1989) 3.24
Adhesion of T lymphoblasts to epidermal keratinocytes is regulated by interferon gamma and is mediated by intercellular adhesion molecule 1 (ICAM-1). J Exp Med (1988) 3.23
The dynamic regulation of integrin adhesiveness. Curr Biol (1994) 3.21
A subpopulation of Mac-1 (CD11b/CD18) molecules mediates neutrophil adhesion to ICAM-1 and fibrinogen. J Cell Biol (1993) 3.14
Inherited deficiency of the Mac-1, LFA-1, p150,95 glycoprotein family and its molecular basis. J Exp Med (1984) 3.14
The T lymphocyte glycoprotein CD2 binds the cell surface ligand LFA-3. Nature (1987) 3.13
ICAM-1 a ligand for LFA-1-dependent adhesion of B, T and myeloid cells. Nature (1988) 3.12
A soluble form of intercellular adhesion molecule-1 inhibits rhinovirus infection. Nature (1990) 3.10
Characterization of ICAM-2 and evidence for a third counter-receptor for LFA-1. J Exp Med (1991) 3.08
Lymphocyte function-associated antigen 1 (LFA-1): a surface antigen distinct from Lyt-2,3 that participates in T lymphocyte-mediated killing. Proc Natl Acad Sci U S A (1981) 3.06
Activation of cultured human endothelial cells by recombinant lymphotoxin: comparison with tumor necrosis factor and interleukin 1 species. J Immunol (1987) 3.06
Mac-2, a novel 32,000 Mr mouse macrophage subpopulation-specific antigen defined by monoclonal antibodies. J Immunol (1982) 2.99
Monoclonal antibody to a novel lymphocyte function-associated antigen (LFA-1): mechanism of blockade of T lymphocyte-mediated killing and effects on other T and B lymphocyte functions. J Immunol (1981) 2.96
High endothelial venules (HEVs): specialized endothelium for lymphocyte migration. Immunol Today (1995) 2.95
Cross-reaction of a rat-anti-mouse phagocyte-specific monoclonal antibody (anti-Mac-1) with human monocytes and natural killer cells. J Immunol (1981) 2.94
Role of lymphocyte adhesion receptors in transient interactions and cell locomotion. Annu Rev Immunol (1991) 2.93
Neutrophils roll on E-selectin. J Immunol (1993) 2.91
The I domain is a major recognition site on the leukocyte integrin Mac-1 (CD11b/CD18) for four distinct adhesion ligands. J Cell Biol (1993) 2.87
An automatic braking system that stabilizes leukocyte rolling by an increase in selectin bond number with shear. J Cell Biol (1999) 2.79
Mapping of antigenic and functional epitopes on the alpha- and beta-subunits of two related mouse glycoproteins involved in cell interactions, LFA-1 and Mac-1. J Exp Med (1983) 2.78
Implications for familial hypercholesterolemia from the structure of the LDL receptor YWTD-EGF domain pair. Nat Struct Biol (2001) 2.77
The major Fc receptor in blood has a phosphatidylinositol anchor and is deficient in paroxysmal nocturnal haemoglobinuria. Nature (1988) 2.66
Visualization of CD2 interaction with LFA-3 and determination of the two-dimensional dissociation constant for adhesion receptors in a contact area. J Cell Biol (1996) 2.61
C-terminal opening mimics 'inside-out' activation of integrin alpha5beta1. Nat Struct Biol (2001) 2.58
A novel lymphocyte function-associated antigen (LFA-1): cellular distribution, quantitative expression, and structure. J Immunol (1981) 2.52
Computational design of an integrin I domain stabilized in the open high affinity conformation. Nat Struct Biol (2000) 2.45
Dendritic cell and macrophage staining by monoclonal antibodies in tissue sections and epidermal sheets. Am J Pathol (1983) 2.38
Functional evidence that intercellular adhesion molecule-1 (ICAM-1) is a ligand for LFA-1-dependent adhesion in T cell-mediated cytotoxicity. Eur J Immunol (1988) 2.35
Reversibly locking a protein fold in an active conformation with a disulfide bond: integrin alphaL I domains with high affinity and antagonist activity in vivo. Proc Natl Acad Sci U S A (2001) 2.35
Regulation of adhesion of ICAM-1 by the cytoplasmic domain of LFA-1 integrin beta subunit. Science (1991) 2.34
Leukocyte adhesion receptors are stored in peroxidase-negative granules of human neutrophils. J Exp Med (1987) 2.33
Deficiency of a surface membrane glycoprotein (Mo1) in man. J Clin Invest (1984) 2.29
Purified lymphocyte function-associated antigen 3 binds to CD2 and mediates T lymphocyte adhesion. J Exp Med (1987) 2.28
Structural homology of a macrophage differentiation antigen and an antigen involved in T-cell-mediated killing. Nature (1982) 2.26
Intercellular adhesion molecule 3, a third adhesion counter-receptor for lymphocyte function-associated molecule 1 on resting lymphocytes. J Exp Med (1992) 2.24
Influence of receptor lateral mobility on adhesion strengthening between membranes containing LFA-3 and CD2. J Cell Biol (1991) 2.24
LFA-1 and Lyt-2,3, molecules associated with T lymphocyte-mediated killing; and Mac-1, an LFA-1 homologue associated with complement receptor function. Immunol Rev (1982) 2.23
Heterogeneous mutations in the beta subunit common to the LFA-1, Mac-1, and p150,95 glycoproteins cause leukocyte adhesion deficiency. Cell (1987) 2.23
Domains in plexins: links to integrins and transcription factors. Trends Biochem Sci (1999) 2.23
Regulated expression of the Mac-1, LFA-1, p150,95 glycoprotein family during leukocyte differentiation. J Immunol (1986) 2.21
Cerebral protection in homozygous null ICAM-1 mice after middle cerebral artery occlusion. Role of neutrophil adhesion in the pathogenesis of stroke. J Clin Invest (1996) 2.19
Monoclonal antibodies specific for rat IgG1, IgG2a, and IgG2b subclasses, and kappa chain monotypic and allotypic determinants: reagents for use with rat monoclonal antibodies. Hybridoma (1982) 2.14
Locking in alternate conformations of the integrin alphaLbeta2 I domain with disulfide bonds reveals functional relationships among integrin domains. Proc Natl Acad Sci U S A (2001) 2.12
Thymocyte binding to human thymic epithelial cells is inhibited by monoclonal antibodies to CD-2 and LFA-3 antigens. J Immunol (1987) 2.11
Interactions through L-selectin between leukocytes and adherent leukocytes nucleate rolling adhesions on selectins and VCAM-1 in shear flow. J Cell Biol (1996) 2.11
Selectin receptor-ligand bonds: Formation limited by shear rate and dissociation governed by the Bell model. Proc Natl Acad Sci U S A (2001) 2.08
cDNA cloning and complete primary structure of the alpha subunit of a leukocyte adhesion glycoprotein, p150,95. EMBO J (1987) 2.06
Anchoring mechanisms for LFA-3 cell adhesion glycoprotein at membrane surface. Nature (1987) 2.06
Association of intercellular adhesion molecule-1 (ICAM-1) with actin-containing cytoskeleton and alpha-actinin. J Cell Biol (1992) 2.02
Rolling and transient tethering of leukocytes on antibodies reveal specializations of selectins. Proc Natl Acad Sci U S A (1997) 2.01
Mac-1 antigen: quantitative expression in macrophage populations and tissues, and immunofluorescent localization in spleen. J Immunol (1982) 1.98
Quantitation of L-selectin distribution on human leukocyte microvilli by immunogold labeling and electron microscopy. J Histochem Cytochem (1996) 1.97
Tissue distribution, structural characterization, and biosynthesis of Mac-3, a macrophage surface glycoprotein exhibiting molecular weight heterogeneity. J Biol Chem (1983) 1.96
Molecular cloning and characterization of a murine pre-B-cell growth-stimulating factor/stromal cell-derived factor 1 receptor, a murine homolog of the human immunodeficiency virus 1 entry coreceptor fusin. Proc Natl Acad Sci U S A (1996) 1.95
Cell adhesion. Sticky sugars for selectins. Nature (1991) 1.94
The alpha subunit cytoplasmic domain regulates the assembly and adhesiveness of integrin lymphocyte function-associated antigen-1. J Immunol (1997) 1.93
Chemoattractant-regulated mobilization of a novel intracellular compartment in human neutrophils. Science (1987) 1.91