1
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Genome-wide association study identifies novel breast cancer susceptibility loci.
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Nature
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2007
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29.23
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2
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Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
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Nat Genet
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2010
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23.08
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3
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Hundreds of variants clustered in genomic loci and biological pathways affect human height.
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Nature
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2010
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20.01
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4
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Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
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Nature
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2011
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13.23
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5
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Large-scale genotyping identifies 41 new loci associated with breast cancer risk.
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Nat Genet
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2013
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8.24
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6
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A common coding variant in CASP8 is associated with breast cancer risk.
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Nat Genet
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2007
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7.35
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7
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Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2.
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Nat Genet
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2009
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7.30
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8
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Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics.
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PLoS Genet
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2008
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6.22
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9
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Progress in tuberculosis control and the evolving public-health system in China.
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Lancet
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2007
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4.86
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10
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Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies.
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J Natl Cancer Inst
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2010
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4.54
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11
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Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer.
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Nat Genet
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2013
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4.35
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12
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Genome-wide association studies identify four ER negative-specific breast cancer risk loci.
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Nat Genet
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2013
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3.81
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13
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Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci.
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Nat Genet
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2011
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3.46
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14
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Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies.
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Nat Genet
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2010
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3.37
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15
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A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer.
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Nat Genet
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2011
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3.37
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16
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Niemann-Pick C1 Like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis.
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J Biol Chem
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2004
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3.27
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17
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Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
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Nat Genet
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2013
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3.25
|
18
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Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q.
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Am J Hum Genet
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2005
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3.24
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19
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Genome-wide association analysis identifies three new breast cancer susceptibility loci.
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Nat Genet
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2012
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3.20
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20
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Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder.
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Am J Hum Genet
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2003
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3.02
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21
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Risk of estrogen receptor-positive and -negative breast cancer and single-nucleotide polymorphism 2q35-rs13387042.
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J Natl Cancer Inst
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2009
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2.88
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22
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Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium.
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Hum Mol Genet
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2011
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2.72
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23
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A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci.
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Nat Genet
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2010
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2.62
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24
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A genomewide screen of 345 families for autism-susceptibility loci.
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Am J Hum Genet
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2003
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2.51
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25
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A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11.
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Hum Mol Genet
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2012
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2.45
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26
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Genome-wide association study of follicular lymphoma identifies a risk locus at 6p21.32.
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Nat Genet
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2010
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2.37
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27
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Genetic structure of the Han Chinese population revealed by genome-wide SNP variation.
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Am J Hum Genet
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2009
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2.33
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28
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Evidence for a language quantitative trait locus on chromosome 7q in multiplex autism families.
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Am J Hum Genet
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2001
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2.29
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29
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Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia.
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Nat Genet
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2012
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2.26
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30
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Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers.
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Am J Hum Genet
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2013
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2.24
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31
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Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways.
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Nat Genet
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2012
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2.12
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32
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A genome-wide association study in Han Chinese identifies new susceptibility loci for ankylosing spondylitis.
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Nat Genet
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2011
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2.05
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33
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Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.
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Nat Genet
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2012
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2.05
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34
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Identification of two new loci at IL23R and RAB32 that influence susceptibility to leprosy.
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Nat Genet
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2011
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1.95
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35
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GWAS identifies novel susceptibility loci on 6p21.32 and 21q21.3 for hepatocellular carcinoma in chronic hepatitis B virus carriers.
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PLoS Genet
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2012
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1.86
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36
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Genome-wide association study identifies a common variant associated with risk of endometrial cancer.
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Nat Genet
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2011
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1.84
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37
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Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.
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PLoS Genet
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2011
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1.81
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38
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Contribution of root respiration to soil respiration in a C3/C4 mixed grassland.
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J Biosci
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2005
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1.80
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39
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Genome-wide association study of Crohn's disease in Koreans revealed three new susceptibility loci and common attributes of genetic susceptibility across ethnic populations.
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Gut
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2013
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1.79
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40
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Common breast cancer susceptibility loci are associated with triple-negative breast cancer.
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Cancer Res
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2011
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1.65
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41
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Association of ESR1 gene tagging SNPs with breast cancer risk.
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Hum Mol Genet
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2009
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1.58
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42
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GWAS of follicular lymphoma reveals allelic heterogeneity at 6p21.32 and suggests shared genetic susceptibility with diffuse large B-cell lymphoma.
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PLoS Genet
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2011
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1.58
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43
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Genome-wide association analyses in Han Chinese identify two new susceptibility loci for amyotrophic lateral sclerosis.
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Nat Genet
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2013
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1.57
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44
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Evidence of gene-environment interactions between common breast cancer susceptibility loci and established environmental risk factors.
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PLoS Genet
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2013
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1.56
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45
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A combined analysis of genome-wide association studies in breast cancer.
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Breast Cancer Res Treat
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2010
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1.54
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46
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Retrotransposons control fruit-specific, cold-dependent accumulation of anthocyanins in blood oranges.
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Plant Cell
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2012
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1.52
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47
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Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control study.
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Breast Cancer Res
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2010
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1.51
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48
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Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.
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Nat Genet
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2013
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1.49
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49
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Breast cancer risk prediction and individualised screening based on common genetic variation and breast density measurement.
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Breast Cancer Res
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2012
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1.47
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50
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A five-year follow-up study on the pathological changes of gastric mucosa after H. pylori eradication.
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Chin Med J (Engl)
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2003
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1.46
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51
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Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1.
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Am J Hum Genet
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2013
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1.39
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52
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Comparing methods for performing trans-ethnic meta-analysis of genome-wide association studies.
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Hum Mol Genet
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2013
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1.34
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53
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Lactate dehydrogenase A in cancer: a promising target for diagnosis and therapy.
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IUBMB Life
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2013
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1.31
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54
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Comprehensive evaluation of common genetic variation within LRRK2 reveals evidence for association with sporadic Parkinson's disease.
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Hum Mol Genet
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2005
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1.30
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55
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Five polymorphisms and breast cancer risk: results from the Breast Cancer Association Consortium.
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Cancer Epidemiol Biomarkers Prev
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2009
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1.29
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56
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CHEK2*1100delC heterozygosity in women with breast cancer associated with early death, breast cancer-specific death, and increased risk of a second breast cancer.
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J Clin Oncol
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2012
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1.29
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57
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Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer.
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Carcinogenesis
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2013
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1.28
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58
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11q13 is a susceptibility locus for hormone receptor positive breast cancer.
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Hum Mutat
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2012
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1.26
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59
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SiO2 nanoparticles induce cytotoxicity and protein expression alteration in HaCaT cells.
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Part Fibre Toxicol
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2010
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1.24
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60
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Is 18F-FDG PET accurate to predict neoadjuvant therapy response in breast cancer? A meta-analysis.
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Breast Cancer Res Treat
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2011
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1.24
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61
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Linkage disequilibrium mapping of CHEK2: common variation and breast cancer risk.
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PLoS Med
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2006
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1.23
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62
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The role of genetic breast cancer susceptibility variants as prognostic factors.
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Hum Mol Genet
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2012
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1.23
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63
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Four new families with autosomal dominant partial epilepsy with auditory features: clinical description and linkage to chromosome 10q24.
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Epilepsia
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2002
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1.21
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64
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Mutational dynamics of the SARS coronavirus in cell culture and human populations isolated in 2003.
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BMC Infect Dis
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2004
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1.21
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65
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Multi-variant pathway association analysis reveals the importance of genetic determinants of estrogen metabolism in breast and endometrial cancer susceptibility.
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PLoS Genet
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2010
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1.19
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66
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New loci associated with chronic hepatitis B virus infection in Han Chinese.
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Nat Genet
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2013
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1.18
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67
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Comparison of 6q25 breast cancer hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC).
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PLoS One
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2012
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1.13
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68
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Short-chain fatty acids act as antiinflammatory mediators by regulating prostaglandin E(2) and cytokines.
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World J Gastroenterol
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2009
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1.10
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69
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Association of TNFSF15 with Crohn's disease in Koreans.
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Am J Gastroenterol
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2008
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1.10
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70
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Catalytic activity of human ADAM33.
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J Biol Chem
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2003
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1.07
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71
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Genetic variation of promoter sequence modulates XBP1 expression and genetic risk for vitiligo.
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PLoS Genet
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2009
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1.07
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72
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Identification of inherited genetic variations influencing prognosis in early-onset breast cancer.
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Cancer Res
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2013
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1.06
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73
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Natural positive selection and north-south genetic diversity in East Asia.
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Eur J Hum Genet
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2011
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1.06
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74
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The genetic structure of the Swedish population.
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PLoS One
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2011
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1.05
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75
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A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and supports a common genetic spectrum for breast cancer at any age.
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Cancer Epidemiol Biomarkers Prev
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2014
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1.03
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76
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Deletion of the WD40 domain of LRRK2 in Zebrafish causes Parkinsonism-like loss of neurons and locomotive defect.
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PLoS Genet
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2010
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1.03
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77
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Pathway-based analysis using reduced gene subsets in genome-wide association studies.
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BMC Bioinformatics
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2011
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1.02
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78
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Methylation of PARP-1 promoter involved in the regulation of nano-SiO2-induced decrease of PARP-1 mRNA expression.
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Toxicol Lett
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2012
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1.02
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79
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A genome-wide association scan on estrogen receptor-negative breast cancer.
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Breast Cancer Res
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2010
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1.02
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80
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[Virological and serological surveys for H9N2 subtype of influenza A virus in chickens and men in Shenzhen city].
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Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi
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2002
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1.01
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81
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Human ADAM33: protein maturation and localization.
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Biochem Biophys Res Commun
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2003
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1.01
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82
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ESR1 and EGF genetic variation in relation to breast cancer risk and survival.
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Breast Cancer Res
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2008
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1.00
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83
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Genome-wide association study for atopy and allergic rhinitis in a Singapore Chinese population.
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PLoS One
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2011
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1.00
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84
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Coding variants at hexa-allelic amino acid 13 of HLA-DRB1 explain independent SNP associations with follicular lymphoma risk.
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Am J Hum Genet
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2013
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1.00
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85
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Nuclear factor kappa B signaling initiates early differentiation of neural stem cells.
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Stem Cells
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2012
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0.99
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86
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SgD-CNV, a database for common and rare copy number variants in three Asian populations.
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Hum Mutat
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2011
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0.99
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87
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Progesterone receptor gene variants and risk of endometrial cancer.
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Carcinogenesis
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2010
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0.98
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SiO(2) nanoparticles induce global genomic hypomethylation in HaCaT cells.
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Biochem Biophys Res Commun
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2010
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0.98
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89
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Association of single nucleotide polymorphism rs6903956 on chromosome 6p24.1 with coronary artery disease and lipid levels in different ethnic groups of the Singaporean population.
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Clin Biochem
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2013
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0.98
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The visible transmittance and solar modulation ability of VO2 flexible foils simultaneously improved by Ti doping: an optimization and first principle study.
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Phys Chem Chem Phys
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2013
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0.98
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Swedish population substructure revealed by genome-wide single nucleotide polymorphism data.
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PLoS One
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2011
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0.97
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Usefulness of 18F-FDG PET, combined FDG-PET/CT and EUS in diagnosing primary pancreatic carcinoma: a meta-analysis.
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Eur J Radiol
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2009
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0.97
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Birth weight, breast cancer susceptibility loci, and breast cancer risk.
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Cancer Causes Control
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Large BRCA1 and BRCA2 genomic rearrangements in Malaysian high risk breast-ovarian cancer families.
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Breast Cancer Res Treat
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2010
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A meta-analysis of interleukin-8 -251 promoter polymorphism associated with gastric cancer risk.
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PLoS One
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Identification of four novel variants that influence central corneal thickness in multi-ethnic Asian populations.
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Hum Mol Genet
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2011
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Common polymorphisms in ITGA2, PON1 and THBS2 are associated with coronary atherosclerosis in a candidate gene association study of the Chinese Han population.
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J Hum Genet
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Proviral insertion in murine lymphomas 2 (PIM2) oncogene phosphorylates pyruvate kinase M2 (PKM2) and promotes glycolysis in cancer cells.
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J Biol Chem
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9q31.2-rs865686 as a susceptibility locus for estrogen receptor-positive breast cancer: evidence from the Breast Cancer Association Consortium.
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Cancer Epidemiol Biomarkers Prev
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2012
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0.95
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100
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Genome-wide association study of B cell non-Hodgkin lymphoma identifies 3q27 as a susceptibility locus in the Chinese population.
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Nat Genet
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Comprehensive analysis of the ATM, CHEK2 and ERBB2 genes in relation to breast tumour characteristics and survival: a population-based case-control and follow-up study.
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Breast Cancer Res
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Preparation of icariside II from icariin by enzymatic hydrolysis method.
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Identification of IL18RAP/IL18R1 and IL12B as leprosy risk genes demonstrates shared pathogenesis between inflammation and infectious diseases.
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The role of school engagement in preventing adolescent delinquency and substance use: a survival analysis.
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Association of variants in FRAP1 and PDGFRA with corneal curvature in Asian populations from Singapore.
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Diagnostic value of FDG-PET in recurrent colorectal carcinoma: a meta-analysis.
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Genome-wide copy number variation study in anorectal malformations.
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Missense variants in ATM in 26,101 breast cancer cases and 29,842 controls.
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Exome sequencing and digital PCR analyses reveal novel mutated genes related to the metastasis of pancreatic ductal adenocarcinoma.
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Cancer Biol Ther
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A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2.
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Effect of low dose bisphenol A on the early differentiation of human embryonic stem cells into mammary epithelial cells.
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Association study confirmed susceptibility loci with keloid in the Chinese Han population.
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New understanding of the difference of photocatalytic activity among anatase, rutile and brookite TiO2.
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Diverse phenotype of Brooke-Spiegler syndrome associated with a nonsense mutation in the CYLD tumor suppressor gene.
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A statistical method for region-based meta-analysis of genome-wide association studies in genetically diverse populations.
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Candidate locus analysis of the TERT-CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk.
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18F-FDG-PET evaluation of treatment response to neo-adjuvant therapy in patients with locally advanced rectal cancer: a meta-analysis.
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A comprehensive association analysis of homocysteine metabolic pathway genes in Singaporean Chinese with ischemic stroke.
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Identification of a novel percent mammographic density locus at 12q24.
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Analysis of proteomic components of sera from patients with uremia by two dimensional electrophoresis and matrix assisted laser desorption/ ionization time of flight mass spectrometry.
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Genome-wide meta-analysis of five Asian cohorts identifies PDGFRA as a susceptibility locus for corneal astigmatism.
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MicroRNA-122 influences the development of sperm abnormalities from human induced pluripotent stem cells by regulating TNP2 expression.
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Polymorphisms in oxidative stress-related genes and postmenopausal breast cancer risk.
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MiRNA-146a regulates the maturation and differentiation of vascular smooth muscle cells by targeting NF-κB expression.
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Association of cardiovascular and metabolic disease genes with psoriasis.
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Genome-wide association study of ulcerative colitis in Koreans suggests extensive overlapping of genetic susceptibility with Caucasians.
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Effect of ATM, CHEK2 and ERBB2 TAGSNPs and haplotypes on endometrial cancer risk.
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F-doped VO2 nanoparticles for thermochromic energy-saving foils with modified color and enhanced solar-heat shielding ability.
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Genetic variation in the estrogen metabolic pathway and mammographic density as an intermediate phenotype of breast cancer.
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Next-generation sequencing diagnostics for neurological diseases/disorders: from a clinical perspective.
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Polymorphisms in oxidative stress-related genes and mortality in breast cancer patients--potential differential effects by radiotherapy?
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Immunochip analysis identification of 6 additional susceptibility loci for Crohn's disease in Koreans.
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The role of reactive oxygen species in silicon dioxide nanoparticle-induced cytotoxicity and DNA damage in HaCaT cells.
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Replication of genome-wide association study loci for allergic rhinitis and house dust mite sensitization in an Asian population of ethnic Chinese in Singapore.
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A meta-analysis of genome-wide association studies of follicular lymphoma.
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No evidence that GATA3 rs570613 SNP modifies breast cancer risk.
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Breast cancer risk assessment using genetic variants and risk factors in a Singapore Chinese population.
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Platelet-derived growth factor receptor alpha gene mutations in vitiligo vulgaris.
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Genetic modifiers of menopausal hormone replacement therapy and breast cancer risk: a genome-wide interaction study.
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Coffee consumption modifies risk of estrogen-receptor negative breast cancer.
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Rare lysosomal enzyme gene SMPD1 variant (p.R591C) associates with Parkinson's disease.
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Inhibition of lipolysis by mercaptoacetate and etomoxir specifically sensitize drug-resistant lung adenocarcinoma cell to paclitaxel.
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Identification of serum biomarkers for occupational medicamentosa-like dermatitis induced by trichloroethylene using mass spectrometry.
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Germline variation in TP53 regulatory network genes associates with breast cancer survival and treatment outcome.
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Genetic variation in the androgen estrogen conversion pathway in relation to breast cancer prognosticators.
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Effects of childhood body size on breast cancer tumour characteristics.
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Terahertz gas sensing based on a simple one-dimensional photonic crystal cavity with high-quality factors.
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