1
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Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers.
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Cancer Res
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2007
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5.12
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2
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Spontaneous induction of murine pancreatic intraepithelial neoplasia (mPanIN) by acinar cell targeting of oncogenic Kras in adult mice.
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Proc Natl Acad Sci U S A
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2008
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3.43
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3
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Surgical treatment of tertiary hyperparathyroidism: the choice of procedure matters!
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World J Surg
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2007
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2.21
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4
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An orally bioavailable small-molecule inhibitor of Hedgehog signaling inhibits tumor initiation and metastasis in pancreatic cancer.
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Mol Cancer Ther
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2008
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2.21
|
5
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Claudin-4-targeted optical imaging detects pancreatic cancer and its precursor lesions.
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Gut
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2012
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1.55
|
6
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DYRK1B-dependent autocrine-to-paracrine shift of Hedgehog signaling by mutant RAS.
|
Nat Struct Mol Biol
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2010
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1.49
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7
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Inactivation of Brca2 cooperates with Trp53(R172H) to induce invasive pancreatic ductal adenocarcinomas in mice: a mouse model of familial pancreatic cancer.
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Cancer Biol Ther
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2011
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1.45
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8
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Reduced complication rate after modified binding purse-string-mattress sutures pancreatogastrostomy versus duct-to-mucosa pancreaticojejunostomy.
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Surgeon
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2013
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1.41
|
9
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Cyclin-dependent kinase inhibitor Dinaciclib (SCH727965) inhibits pancreatic cancer growth and progression in murine xenograft models.
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Cancer Biol Ther
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2011
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1.18
|
10
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Transabdominal preperitoneal versus totally extraperitoneal repair of inguinal hernia: a meta-analysis of randomized studies.
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Am J Surg
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2013
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1.11
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11
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German national case collection for familial pancreatic cancer (FaPaCa): ten years experience.
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Fam Cancer
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2011
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1.06
|
12
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Pancreatitis risk in primary hyperparathyroidism: relation to mutations in the SPINK1 trypsin inhibitor (N34S) and the cystic fibrosis gene.
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Am J Gastroenterol
|
2007
|
1.03
|
13
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Prospective evaluation of imaging procedures for the detection of pancreaticoduodenal endocrine tumors in patients with multiple endocrine neoplasia type 1.
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World J Surg
|
2004
|
0.99
|
14
|
Outcome of duodenopancreatic resections in patients with multiple endocrine neoplasia type 1.
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Ann Surg
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2005
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0.98
|
15
|
Screening of patients with multiple endocrine neoplasia type 1 (MEN-1): a critical analysis of its value.
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World J Surg
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2009
|
0.92
|
16
|
Palladin mutation causes familial pancreatic cancer: absence in European families.
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PLoS Med
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2007
|
0.91
|
17
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Frequent methylation-associated silencing of the tissue inhibitor of metalloproteinase-3 gene in pancreatic endocrine tumors.
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J Clin Endocrinol Metab
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2003
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0.89
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18
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Higher risk of aggressive pancreatic neuroendocrine tumors in MEN1 patients with MEN1 mutations affecting the CHES1 interacting MENIN domain.
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J Clin Endocrinol Metab
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2014
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0.89
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19
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Microarray analysis reveals differential expression of benign and malignant pheochromocytoma.
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Endocr Relat Cancer
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2010
|
0.88
|
20
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Prevalence of BRCA2 and CDKN2a mutations in German familial pancreatic cancer families.
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Fam Cancer
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2010
|
0.88
|
21
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LCN2 and TIMP1 as Potential Serum Markers for the Early Detection of Familial Pancreatic Cancer.
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Transl Oncol
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2013
|
0.88
|
22
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Expression of the transcription factor snail and its target gene twist are associated with malignancy in pheochromocytomas.
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Ann Surg Oncol
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2009
|
0.88
|
23
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Long-term results of surgery for pancreatic neuroendocrine neoplasms in patients with MEN1.
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Langenbecks Arch Surg
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2011
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0.88
|
24
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Rap1/B-Raf signaling is activated in neuroendocrine tumors of the digestive tract and Raf kinase inhibition constitutes a putative therapeutic target.
|
Neuroendocrinology
|
2007
|
0.87
|
25
|
RNASEL germline variants are associated with pancreatic cancer.
|
Int J Cancer
|
2005
|
0.86
|
26
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PanIN-specific regulation of Wnt signaling by HIF2α during early pancreatic tumorigenesis.
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Cancer Res
|
2013
|
0.86
|
27
|
Expression of hedgehog signalling pathway in anaplastic thyroid cancer.
|
Endocrine
|
2013
|
0.84
|
28
|
Low frequency of CHEK2 mutations in familial pancreatic cancer.
|
Fam Cancer
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2006
|
0.84
|
29
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Clinical impact of TP53 alterations in adrenocortical carcinomas.
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Langenbecks Arch Surg
|
2011
|
0.84
|
30
|
Multimodal treatment of sporadic and inherited neuroendocrine tumors of the thymus.
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Surgery
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2008
|
0.83
|
31
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Increased rate of clinically relevant pancreatic fistula after deep enucleation of small pancreatic tumors.
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Langenbecks Arch Surg
|
2014
|
0.82
|
32
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RIO kinase 3 acts as a SUFU-dependent positive regulator of Hedgehog signaling.
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Cell Signal
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2013
|
0.81
|
33
|
Partial pancreaticoduodenectomy can provide cure for duodenal gastrinoma associated with multiple endocrine neoplasia type 1.
|
Ann Surg
|
2013
|
0.81
|
34
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Long-Term Outcomes of Surgical Management of Pancreatic Neuroendocrine Tumors with Synchronous Liver Metastases.
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Neuroendocrinology
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2015
|
0.81
|
35
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Calcitonin-secreting pancreatic endocrine tumors: systematic analysis of a rare tumor entity.
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Pancreas
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2011
|
0.81
|
36
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Novel molecular targets for the treatment of gastroenteropancreatic endocrine tumors: answers and unsolved problems.
|
Int J Mol Sci
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2012
|
0.81
|
37
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Enucleation and limited pancreatic resection provide long-term cure for insulinoma in multiple endocrine neoplasia type 1.
|
Neuroendocrinology
|
2013
|
0.80
|
38
|
Aspirin prolongs survival and reduces the number of Foxp3+ regulatory T cells in a genetically engineered mouse model of pancreatic cancer.
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Langenbecks Arch Surg
|
2013
|
0.80
|
39
|
Outcome in patients with long-term treatment in a surgical intensive care unit.
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Langenbecks Arch Surg
|
2012
|
0.79
|
40
|
Outcome of surgery for ileojejunal neuroendocrine tumors.
|
Surg Today
|
2012
|
0.78
|
41
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Mutations and polymorphisms in the SDHB, SDHD, VHL, and RET genes in sporadic and familial pheochromocytomas.
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Endocrine
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2009
|
0.77
|
42
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Corrigendum: Identification of a novel actin-dependent signal transducing module allows for the targeted degradation of GLI1.
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Nat Commun
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2015
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0.76
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43
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A Pancreatic Polypeptide-Producing Pancreatic Tumor Causing WDHA Syndrome.
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Case Rep Gastroenterol
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2008
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0.76
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44
|
Bronchopulmonary Neuroendocrine Neoplasms and Their Precursor Lesions in Multiple Endocrine Neoplasia Type 1.
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Neuroendocrinology
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2015
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0.76
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45
|
Fast-growing pancreatic neuroendocrine carcinoma in a patient with multiple endocrine neoplasia type 1: a case report.
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J Med Case Rep
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2008
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0.75
|
46
|
Molecular Characterization and Pathogenesis of Intraductal Papillary Mucinous Neoplasms of the Pancreas.
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Eur Surg Res
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2015
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0.75
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47
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Shortness: an unknown phenotype of multiple endocrine neoplasia type 1.
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Eur J Endocrinol
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2013
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0.75
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48
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Over-Expression of miRNA miR-7-5p is a Potential Biomarker in Neuroendocrine Neoplasia of the Small Intestine.
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Neuroendocrinology
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2017
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0.75
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49
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Impact of CT-based diagnostic imaging on management and outcome of nonfunctioning pancreatic tumors.
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Langenbecks Arch Surg
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2011
|
0.75
|
50
|
Familial pancreatic cancer: current status.
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Expert Opin Med Diagn
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2007
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0.75
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51
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Robotic-Assisted Approach Improves Vessel Preservation in Spleen-Preserving Distal Pancreatectomy.
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Dig Surg
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2016
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0.75
|