Viola Oorschot

Author PubWeight™ 45.73‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Termination of autophagy and reformation of lysosomes regulated by mTOR. Nature 2010 6.26
2 Bilayered clathrin coats on endosomal vacuoles are involved in protein sorting toward lysosomes. Mol Biol Cell 2002 3.24
3 Localization of the AP-3 adaptor complex defines a novel endosomal exit site for lysosomal membrane proteins. J Cell Biol 2004 2.76
4 Mst4 and Ezrin induce brush borders downstream of the Lkb1/Strad/Mo25 polarization complex. Dev Cell 2009 2.40
5 Short-chain ubiquitination mediates the regulated endocytosis of the aquaporin-2 water channel. Proc Natl Acad Sci U S A 2006 1.91
6 Presenilin 1 mediates the turnover of telencephalin in hippocampal neurons via an autophagic degradative pathway. J Cell Biol 2004 1.65
7 mTrs130 is a component of a mammalian TRAPPII complex, a Rab1 GEF that binds to COPI-coated vesicles. Mol Biol Cell 2009 1.55
8 Sorting nexin 17 facilitates LRP recycling in the early endosome. EMBO J 2005 1.50
9 S6 kinase inactivation impairs growth and translational target phosphorylation in muscle cells maintaining proper regulation of protein turnover. Am J Physiol Cell Physiol 2007 1.44
10 Correlative light-electron microscopy (CLEM) combining live-cell imaging and immunolabeling of ultrathin cryosections. Nat Methods 2008 1.40
11 Rabaptin-5alpha/rabaptin-4 serves as a linker between rab4 and gamma(1)-adaptin in membrane recycling from endosomes. EMBO J 2003 1.39
12 Glycosylation is important for cell surface expression of the water channel aquaporin-2 but is not essential for tetramerization in the endoplasmic reticulum. J Biol Chem 2003 1.32
13 Neuron specific Rab4 effector GRASP-1 coordinates membrane specialization and maturation of recycling endosomes. PLoS Biol 2010 1.18
14 hVps41 and VAMP7 function in direct TGN to late endosome transport of lysosomal membrane proteins. Nat Commun 2013 1.14
15 The RapGEF PDZ-GEF2 is required for maturation of cell-cell junctions. Cell Signal 2008 1.11
16 Involvement of a Golgi-resident GPI-anchored protein in maintenance of the Golgi structure. Mol Biol Cell 2007 1.09
17 Cripto recruits Furin and PACE4 and controls Nodal trafficking during proteolytic maturation. EMBO J 2008 1.09
18 A flippase-independent function of ATP8B1, the protein affected in familial intrahepatic cholestasis type 1, is required for apical protein expression and microvillus formation in polarized epithelial cells. Hepatology 2010 1.03
19 Different characteristics and nucleotide binding properties of inosine monophosphate dehydrogenase (IMPDH) isoforms. PLoS One 2012 0.98
20 The HOPS proteins hVps41 and hVps39 are required for homotypic and heterotypic late endosome fusion. Traffic 2012 0.98
21 Vacuolization of mucolipidosis type II mouse exocrine gland cells represents accumulation of autolysosomes. Mol Biol Cell 2011 0.96
22 Disruption of the Man-6-P targeting pathway in mice impairs osteoclast secretory lysosome biogenesis. Traffic 2011 0.94
23 Cripto localizes Nodal at the limiting membrane of early endosomes. Sci Signal 2008 0.91
24 The Sec7 guanine nucleotide exchange factor GBF1 regulates membrane recruitment of BIG1 and BIG2 guanine nucleotide exchange factors to the trans-Golgi network (TGN). J Biol Chem 2013 0.90
25 Sunitinib and SU11652 inhibit acid sphingomyelinase, destabilize lysosomes, and inhibit multidrug resistance. Mol Cancer Ther 2013 0.90
26 Rab4 function in membrane recycling from early endosomes depends on a membrane to cytoplasm cycle. J Biol Chem 2002 0.89
27 Zebrafish models of BAG3 myofibrillar myopathy suggest a toxic gain of function leading to BAG3 insufficiency. Acta Neuropathol 2014 0.86
28 Zebrafish models for nemaline myopathy reveal a spectrum of nemaline bodies contributing to reduced muscle function. Acta Neuropathol 2015 0.85
29 Rescue of a nephrogenic diabetes insipidus-causing vasopressin V2 receptor mutant by cell-penetrating peptides. J Biol Chem 2007 0.84
30 Presenilin-1-mediated retention of APP derivatives in early biosynthetic compartments. Traffic 2006 0.83
31 Identification of the ubiquitin ligase Triad1 as a regulator of endosomal transport. Biol Open 2012 0.81
32 AP-3 and Rabip4' coordinately regulate spatial distribution of lysosomes. PLoS One 2012 0.79
33 R-SNARE ykt6 resides in membrane-associated protease-resistant protein particles and modulates cell cycle progression when over-expressed. Biol Cell 2012 0.77