PubRank

Joost C M Holthuis

Author PubWeight™ 31.03‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Identification of a family of animal sphingomyelin synthases. EMBO J 2003 3.03
2 Drs2p-related P-type ATPases Dnf1p and Dnf2p are required for phospholipid translocation across the yeast plasma membrane and serve a role in endocytosis. Mol Biol Cell 2003 2.65
3 Folding defects in P-type ATP 8B1 associated with hereditary cholestasis are ameliorated by 4-phenylbutyrate. Hepatology 2010 1.76
4 Both sphingomyelin synthases SMS1 and SMS2 are required for sphingomyelin homeostasis and growth in human HeLa cells. J Biol Chem 2007 1.75
5 The multigenic sphingomyelin synthase family. J Biol Chem 2006 1.75
6 Loss of P4 ATPases Drs2p and Dnf3p disrupts aminophospholipid transport and asymmetry in yeast post-Golgi secretory vesicles. Mol Biol Cell 2006 1.58
7 Tracking down lipid flippases and their biological functions. J Cell Sci 2004 1.49
8 Sphingomyelin synthase-related protein SMSr controls ceramide homeostasis in the ER. J Cell Biol 2009 1.49
9 Cdc50p plays a vital role in the ATPase reaction cycle of the putative aminophospholipid transporter Drs2p. J Biol Chem 2009 1.38
10 CDC50 proteins are critical components of the human class-1 P4-ATPase transport machinery. J Biol Chem 2010 1.13
11 The CLN9 protein, a regulator of dihydroceramide synthase. J Biol Chem 2005 1.06
12 Mechanism and significance of P4 ATPase-catalyzed lipid transport: lessons from a Na+/K+-pump. Biochim Biophys Acta 2009 1.05
13 A flippase-independent function of ATP8B1, the protein affected in familial intrahepatic cholestasis type 1, is required for apical protein expression and microvillus formation in polarized epithelial cells. Hepatology 2010 1.03
14 In vivo profiling and visualization of cellular protein-lipid interactions using bifunctional fatty acids. Angew Chem Int Ed Engl 2013 1.01
15 Sphingomyelin synthase SMS2 displays dual activity as ceramide phosphoethanolamine synthase. J Lipid Res 2009 1.01
16 Membrane contact sites between apicoplast and ER in Toxoplasma gondii revealed by electron tomography. Traffic 2009 0.92
17 Sphingomyelin synthase-related protein SMSr is a suppressor of ceramide-induced mitochondrial apoptosis. J Cell Sci 2013 0.88
18 Ceramide phosphoethanolamine biosynthesis in Drosophila is mediated by a unique ethanolamine phosphotransferase in the Golgi lumen. J Biol Chem 2013 0.85
19 Mapping functional interactions in a heterodimeric phospholipid pump. J Biol Chem 2012 0.83
20 Protein sorting in the late Golgi of Saccharomyces cerevisiae does not require mannosylated sphingolipids. J Biol Chem 2003 0.82
21 A P4-ATPase protein interaction network reveals a link between aminophospholipid transport and phosphoinositide metabolism. J Proteome Res 2010 0.82
22 Pumping lipids with P4-ATPases. Biol Chem 2011 0.79
23 HOR7, a multicopy suppressor of the Ca2+-induced growth defect in sphingolipid mannosyltransferase-deficient yeast. J Biol Chem 2004 0.78
24 The elusive flippases. Curr Biol 2004 0.77
25 Cell biology: A brake on lipid synthesis. Nature 2010 0.77