Published in Mol Cell on May 28, 2010
The diverse and complex roles of NF-κB subunits in cancer. Nat Rev Cancer (2012) 3.75
Nuclear initiated NF-κB signaling: NEMO and ATM take center stage. Cell Res (2010) 1.58
A quantitative proteomic approach of the different stages of colorectal cancer establishes OLFM4 as a new nonmetastatic tumor marker. Mol Cell Proteomics (2011) 1.27
The codon 72 polymorphism of p53 regulates interaction with NF-{kappa}B and transactivation of genes involved in immunity and inflammation. Mol Cell Biol (2011) 1.20
IKK-dependent, NF-κB-independent control of autophagic gene expression. Oncogene (2010) 1.16
AMPKα2 deletion exacerbates neointima formation by upregulating Skp2 in vascular smooth muscle cells. Circ Res (2011) 1.15
PHD1 links cell-cycle progression to oxygen sensing through hydroxylation of the centrosomal protein Cep192. Dev Cell (2013) 1.12
TBK1 kinase addiction in lung cancer cells is mediated via autophagy of Tax1bp1/Ndp52 and non-canonical NF-κB signalling. PLoS One (2012) 1.04
Nuclear factor-κB modulates osteogenesis of periodontal ligament stem cells through competition with β-catenin signaling in inflammatory microenvironments. Cell Death Dis (2013) 1.02
The role of RelA (p65) threonine 505 phosphorylation in the regulation of cell growth, survival, and migration. Mol Biol Cell (2011) 1.02
The c-Rel Transcription Factor in Development and Disease. Genes Cancer (2011) 1.01
The complex interplay between autophagy and NF-κB signaling pathways in cancer cells. Am J Cancer Res (2011) 1.01
c-Myc dependent expression of pro-apoptotic Bim renders HER2-overexpressing breast cancer cells dependent on anti-apoptotic Mcl-1. Mol Cancer (2011) 0.97
p53-dependent regulation of mitochondrial energy production by the RelA subunit of NF-κB. Cancer Res (2011) 0.95
Tissue-specific apoptotic effects of the p53 codon 72 polymorphism in a mouse model. Cell Cycle (2011) 0.93
Adhesion-dependent Skp2 transcription requires selenocysteine tRNA gene transcription-activating factor (STAF). Biochem J (2011) 0.92
Aberrant IKKα and IKKβ cooperatively activate NF-κB and induce EGFR/AP1 signaling to promote survival and migration of head and neck cancer. Oncogene (2013) 0.91
PIASy-mediated Tip60 sumoylation regulates p53-induced autophagy. Cell Cycle (2012) 0.91
The role of homeostatic regulation between tumor suppressor DAB2IP and oncogenic Skp2 in prostate cancer growth. Oncotarget (2014) 0.90
Extracellular tissue transglutaminase activates noncanonical NF-κB signaling and promotes metastasis in ovarian cancer. Neoplasia (2013) 0.88
pRb/E2F-1-mediated caspase-dependent induction of Noxa amplifies the apoptotic effects of the Bcl-2/Bcl-xL inhibitor ABT-737. Cell Death Differ (2013) 0.88
Regulation of the Aurora-A gene following topoisomerase I inhibition: implication of the Myc transcription factor. Mol Cancer (2010) 0.87
p63 maintains keratinocyte proliferative capacity through regulation of Skp2-p130 levels. J Cell Sci (2011) 0.87
The scaffolding protein EBP50 promotes vascular smooth muscle cell proliferation and neointima formation by regulating Skp2 and p21(cip1). Arterioscler Thromb Vasc Biol (2011) 0.84
Two polymorphic residues account for the differences in DNA binding and transcriptional activation by NF-κB proteins encoded by naturally occurring alleles in Nematostella vectensis. J Mol Evol (2011) 0.83
Adenosine monophosphate-activated protein kinase-α2 deficiency promotes vascular smooth muscle cell migration via S-phase kinase-associated protein 2 upregulation and E-cadherin downregulation. Arterioscler Thromb Vasc Biol (2013) 0.81
A compensatory role of NF-κB to p53 in response to 5-FU-based chemotherapy for gastric cancer cell lines. PLoS One (2014) 0.80
Zac1 is a histone acetylation-regulated NF-κB suppressor that mediates histone deacetylase inhibitor-induced apoptosis. Cell Death Differ (2011) 0.79
NFκB regulates expression of Polo-like kinase 4. Cell Cycle (2013) 0.79
STAT3 as a new autophagy regulator. JAKSTAT (2013) 0.79
Emerging roles of p53 and other tumour-suppressor genes in immune regulation. Nat Rev Immunol (2016) 0.78
Roles of the Skp2/p27 axis in the progression of chronic nephropathy. Cell Mol Life Sci (2012) 0.78
Akt Pathway Activation by Human T-cell Leukemia Virus Type 1 Tax Oncoprotein. J Biol Chem (2015) 0.76
TRIP6 regulates p27 KIP1 to promote tumorigenesis. Mol Cell Biol (2013) 0.76
The transcription factor MEF/Elf4 is dually modulated by p53-MDM2 axis and MEF-MDM2 autoregulatory mechanism. J Biol Chem (2014) 0.75
P300 transcriptional repression is mediated by SUMO modification. Mol Cell (2003) 3.67
Active repression of antiapoptotic gene expression by RelA(p65) NF-kappa B. Mol Cell (2004) 3.45
SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1. J Biol Chem (2005) 2.59
The DEAD box protein p68: a novel transcriptional coactivator of the p53 tumour suppressor. EMBO J (2005) 2.12
p53- and Mdm2-independent repression of NF-kappa B transactivation by the ARF tumor suppressor. Mol Cell (2003) 1.92
p53 represses cyclin D1 transcription through down regulation of Bcl-3 and inducing increased association of the p52 NF-kappaB subunit with histone deacetylase 1. Mol Cell Biol (2003) 1.75
SNIP1 is a candidate modifier of the transcriptional activity of c-Myc on E box-dependent target genes. Mol Cell (2006) 1.73
Regulation of p53 tumour suppressor target gene expression by the p52 NF-kappaB subunit. EMBO J (2006) 1.73
Transcriptional profiling of the LPS induced NF-kappaB response in macrophages. BMC Immunol (2007) 1.71
Regulation of NF-kappaB and p53 through activation of ATR and Chk1 by the ARF tumour suppressor. EMBO J (2005) 1.69
DNA-dependent acetylation of p53 by the transcription coactivator p300. J Biol Chem (2002) 1.59
Retracted A cell cycle regulatory network controlling NF-kappaB subunit activity and function. EMBO J (2007) 1.58
Regulation of cyclin D1 RNA stability by SNIP1. Cancer Res (2008) 1.33
Cyclin D1 represses p300 transactivation through a cyclin-dependent kinase-independent mechanism. J Biol Chem (2005) 1.33
The p68 and p72 DEAD box RNA helicases interact with HDAC1 and repress transcription in a promoter-specific manner. BMC Mol Biol (2004) 1.31
p53 and NF-kappaB crosstalk: IKKalpha tips the balance. Mol Cell (2007) 1.30
Differential regulation of c-Jun-dependent transcription by SUMO-specific proteases. J Biol Chem (2005) 1.28
Regulation of cyclin D1 gene expression. Biochem Soc Trans (2010) 1.20
Regulation of NF-kappaB function. Biochem Soc Symp (2006) 1.18
Cisplatin mimics ARF tumor suppressor regulation of RelA (p65) nuclear factor-kappaB transactivation. Cancer Res (2006) 1.15
The ETS domain transcription factor Elk-1 contains a novel class of repression domain. Mol Cell Biol (2002) 1.12
Not just a CDK inhibitor: regulation of transcription by p21(WAF1/CIP1/SDI1). Cell Cycle (2002) 1.10
Nuclear factor-κB, p53, and mitochondria: regulation of cellular metabolism and the Warburg effect. Trends Biochem Sci (2012) 1.09
IEX-1 directly interferes with RelA/p65 dependent transactivation and regulation of apoptosis. Biochim Biophys Acta (2007) 1.03
A238L inhibits NF-ATc2, NF-kappa B, and c-Jun activation through a novel mechanism involving protein kinase C-theta-mediated up-regulation of the amino-terminal transactivation domain of p300. J Immunol (2008) 1.02
Regulation of the RelA (p65) transactivation domain. Biochem Soc Trans (2008) 1.02
The role of RelA (p65) threonine 505 phosphorylation in the regulation of cell growth, survival, and migration. Mol Biol Cell (2011) 1.02
Regulation of RelA (p65) function by the large subunit of replication factor C. Mol Cell Biol (2003) 1.02
Differential regulation of NF-kappaB activation and function by topoisomerase II inhibitors. BMC Cancer (2006) 1.01
The FHA domain protein SNIP1 is a regulator of the cell cycle and cyclin D1 expression. Oncogene (2004) 0.98
Identification and functional characterization of FMN2, a regulator of the cyclin-dependent kinase inhibitor p21. Mol Cell (2013) 0.97
Thr435 phosphorylation regulates RelA (p65) NF-kappaB subunit transactivation. Biochem J (2010) 0.96
p53-dependent regulation of mitochondrial energy production by the RelA subunit of NF-κB. Cancer Res (2011) 0.95
Retracted Regulation of activity and function of the p52 NF-κB subunit following DNA damage. Cell Cycle (2010) 0.92
NF-κB is a critical mediator of BRCA1-induced chemoresistance. Oncogene (2013) 0.88
The p53-inhibitor pifithrin-alpha inhibits firefly luciferase activity in vivo and in vitro. BMC Mol Biol (2003) 0.87
Inhibition of RelA-Ser536 phosphorylation by a competing peptide reduces mouse liver fibrosis without blocking the innate immune response. Hepatology (2013) 0.86
Induction of transcription by p21Waf1/Cip1/Sdi1: role of NFkappaB and effect of non-steroidal anti-inflammatory drugs. Cell Cycle (2004) 0.85
Identification of new mechanisms of cellular response to chemotherapy by tracking changes in post-translational modifications by ubiquitin and ubiquitin-like proteins. J Proteome Res (2014) 0.84
The large subunit of replication factor C interacts with the histone deacetylase, HDAC1. J Biol Chem (2002) 0.84
Induction of transcription through the p300 CRD1 motif by p21WAF1/CIP1 is core promoter specific and cyclin dependent kinase independent. Cell Cycle (2002) 0.84
p21WAF1/CIP1 regulates the p300 sumoylation motif CRD1 through a C-terminal domain independently of cyclin/CDK binding. Cell Cycle (2005) 0.82
ARF the integrator: linking NF-kappaB, p53 and checkpoint kinases. Cell Cycle (2005) 0.82
Reprogramming RelA. Cell Cycle (2004) 0.81
Retracted Phosphorylation of the p52 NF-κB subunit. Cell Cycle (2010) 0.81
A novel form of the RelA nuclear factor kappaB subunit is induced by and forms a complex with the proto-oncogene c-Myc. Biochem J (2002) 0.81
NFκB regulates expression of Polo-like kinase 4. Cell Cycle (2013) 0.79
Friend or foe: emerging role of nuclear factor kappa-light-chain-enhancer of activated B cells in cell senescence. Onco Targets Ther (2013) 0.77
Correction: A238L Inhibits NF-ATc2, NF-κB, and c-Jun Activation through a Novel Mechanism Involving Protein Kinase C-θ-Mediated Up-Regulation of the Amino-Terminal Transactivation Domain of p300. J Immunol (2015) 0.75