Published in PLoS Genet on May 27, 2010
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A mechanism converting psychosocial stress into mononuclear cell activation. Proc Natl Acad Sci U S A (2003) 3.82
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Macrosomia and hyperinsulinaemic hypoglycaemia in patients with heterozygous mutations in the HNF4A gene. PLoS Med (2007) 3.17
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The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse. Gastroenterology (2006) 2.10
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Hnf1alpha (MODY3) controls tissue-specific transcriptional programs and exerts opposed effects on cell growth in pancreatic islets and liver. Mol Cell Biol (2009) 1.58
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Recessive mutations in the INS gene result in neonatal diabetes through reduced insulin biosynthesis. Proc Natl Acad Sci U S A (2010) 1.36
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The miRNA profile of human pancreatic islets and beta-cells and relationship to type 2 diabetes pathogenesis. PLoS One (2013) 1.25
PDX1 deficiency causes mitochondrial dysfunction and defective insulin secretion through TFAM suppression. Cell Metab (2009) 1.21
Functional targets of the monogenic diabetes transcription factors HNF-1alpha and HNF-4alpha are highly conserved between mice and humans. Diabetes (2009) 1.19
Genetic evidence that HNF-1alpha-dependent transcriptional control of HNF-4alpha is essential for human pancreatic beta cell function. J Clin Invest (2002) 1.16
Lineage fate of ductular reactions in liver injury and carcinogenesis. J Clin Invest (2015) 1.02
Ins1(Cre) knock-in mice for beta cell-specific gene recombination. Diabetologia (2014) 0.99
Targeted deficiency of the transcriptional activator Hnf1alpha alters subnuclear positioning of its genomic targets. PLoS Genet (2008) 0.99
Plasticity of adult human pancreatic duct cells by neurogenin3-mediated reprogramming. PLoS One (2012) 0.97
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GATA believe it: new essential regulators of pancreas development. J Clin Invest (2012) 0.91
Gene expression dynamics after murine pancreatitis unveils novel roles for Hnf1α in acinar cell homeostasis. Gut (2011) 0.91
Ring1b bookmarks genes in pancreatic embryonic progenitors for repression in adult β cells. Genes Dev (2012) 0.91
The FOXP1, FOXP2 and FOXP4 transcription factors are required for islet alpha cell proliferation and function in mice. Diabetologia (2015) 0.86
Hnf1α (MODY3) regulates β-cell-enriched MafA transcription factor expression. Mol Endocrinol (2010) 0.84
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Pulmonary alveolar microlithiasis and pregnancy. J Matern Fetal Neonatal Med (2006) 0.82
A novel -192c/g mutation in the proximal P2 promoter of the hepatocyte nuclear factor-4 alpha gene (HNF4A) associates with late-onset diabetes. Diabetes (2006) 0.81
Mapping open chromatin with formaldehyde-assisted isolation of regulatory elements. Methods Mol Biol (2011) 0.81
The complete genomic sequence of an in vivo low replicating BLV strain. Virol J (2009) 0.81
Removing the brakes on cell identity. Dev Cell (2011) 0.78
Hepatic nuclear factor 1alpha (HNF1alpha) dysfunction down-regulates X-box-binding protein 1 (XBP1) and sensitizes beta-cells to endoplasmic reticulum stress. J Biol Chem (2011) 0.78
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Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity. PLoS One (2010) 0.77
Chromatin immunoprecipitation using isolated islets of Langerhans. Methods Mol Med (2003) 0.77
HLA-DQ haplotypes in Spanish and German families with Graves' disease: contribution to DQA1*0501-DQB1*0301 mediated genetic susceptibility from fathers. Thyroid (2007) 0.75
Cinacalcet for management of hypercalcemia secondary to calcium-sensing receptor mutation. Endocrinol Nutr (2012) 0.75