Neuropsychology of the prodrome to psychosis in the NAPLS consortium: relationship to family history and conversion to psychosis.

PubWeight™: 2.54‹?› | Rank: Top 2%

🔗 View Article (PMC 3332118)

Published in Arch Gen Psychiatry on June 01, 2010

Authors

Larry J Seidman1, Anthony J Giuliano, Eric C Meyer, Jean Addington, Kristin S Cadenhead, Tyrone D Cannon, Thomas H McGlashan, Diana O Perkins, Ming T Tsuang, Elaine F Walker, Scott W Woods, Carrie E Bearden, Bruce K Christensen, Keith Hawkins, Robert Heaton, Richard S E Keefe, Robert Heinssen, Barbara A Cornblatt, North American Prodrome Longitudinal Study (NAPLS) Group

Author Affiliations

1: Department of Psychiatry, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA. lseidman@bidmc.harvard.edu

Articles citing this

(truncated to the top 100)

Rethinking schizophrenia. Nature (2010) 4.85

The psychosis high-risk state: a comprehensive state-of-the-art review. JAMA Psychiatry (2013) 4.16

Neuropsychological decline in schizophrenia from the premorbid to the postonset period: evidence from a population-representative longitudinal study. Am J Psychiatry (2014) 2.51

Dendritic spine pathology in schizophrenia. Neuroscience (2012) 1.91

Psychosis Prevention: A Modified Clinical High Risk Perspective From the Recognition and Prevention (RAP) Program. Am J Psychiatry (2015) 1.75

Comorbid depressive and anxiety disorders in 509 individuals with an at-risk mental state: impact on psychopathology and transition to psychosis. Schizophr Bull (2012) 1.58

Subthreshold psychotic symptoms in 22q11.2 deletion syndrome. J Am Acad Child Adolesc Psychiatry (2014) 1.49

Increased intra-individual variability of cognitive processing in subjects at risk mental state and schizophrenia patients. PLoS One (2013) 1.44

Risk factors for psychosis: impaired social and role functioning. Schizophr Bull (2011) 1.43

Neurocognitive predictors of work outcome in recent-onset schizophrenia. Schizophr Bull (2011) 1.38

Early recognition and disease prediction in the at-risk mental states for psychosis using neurocognitive pattern classification. Schizophr Bull (2011) 1.36

Characterization of neurophysiologic and neurocognitive biomarkers for use in genomic and clinical outcome studies of schizophrenia. PLoS One (2012) 1.28

Biomarkers and clinical staging in psychiatry. World Psychiatry (2014) 1.22

Neurocognition in youth and young adults under age 30 at familial risk for schizophrenia: a quantitative and qualitative review. Cogn Neuropsychiatry (2012) 1.19

Automatic sensory information processing abnormalities across the illness course of schizophrenia. Psychol Med (2011) 1.18

Glutamate levels in the associative striatum before and after 4 weeks of antipsychotic treatment in first-episode psychosis: a longitudinal proton magnetic resonance spectroscopy study. JAMA Psychiatry (2013) 1.17

Prediction and prevention of schizophrenia: what has been achieved and where to go next? World Psychiatry (2011) 1.15

The case for including Attenuated Psychotic Symptoms Syndrome in DSM-5 as a psychosis risk syndrome. Schizophr Res (2010) 1.14

The 22q11.2 deletion syndrome as a window into complex neuropsychiatric disorders over the lifespan. Biol Psychiatry (2013) 1.11

Neuropsychological profiles in individuals at clinical high risk for psychosis: relationship to psychosis and intelligence. Schizophr Res (2010) 1.11

The relationship of neurocognition and negative symptoms to social and role functioning over time in individuals at clinical high risk in the first phase of the North American Prodrome Longitudinal Study. Schizophr Bull (2014) 1.11

Prodromal psychosis detection in a counseling center population in China: an epidemiological and clinical study. Schizophr Res (2013) 1.06

Neurocognition in the extended psychosis phenotype: performance of a community sample of adolescents with psychotic symptoms on the MATRICS neurocognitive battery. Schizophr Bull (2012) 1.05

Cortical circuit dysfunction and cognitive deficits in schizophrenia--implications for preemptive interventions. Eur J Neurosci (2012) 1.04

Early and broadly defined psychosis risk mental states. Schizophr Res (2010) 1.01

Premorbid functional development and conversion to psychosis in clinical high-risk youths. Dev Psychopathol (2013) 0.99

Disease prediction in the at-risk mental state for psychosis using neuroanatomical biomarkers: results from the FePsy study. Schizophr Bull (2011) 0.96

Neuropsychological performance and family history in children at age 7 who develop adult schizophrenia or bipolar psychosis in the New England Family Studies. Psychol Med (2012) 0.95

Sleep correlates of cognition in early course psychotic disorders. Schizophr Res (2011) 0.95

Social cognition in 22q11.2 microdeletion syndrome: relevance to psychosis? Schizophr Res (2012) 0.94

Using genetic, cognitive and multi-modal neuroimaging data to identify ultra-high-risk and first-episode psychosis at the individual level. Psychol Med (2013) 0.94

A familial risk enriched cohort as a platform for testing early interventions to prevent severe mental illness. BMC Psychiatry (2014) 0.94

An Individualized Risk Calculator for Research in Prodromal Psychosis. Am J Psychiatry (2016) 0.94

Marked reduction of soluble superoxide dismutase-1 (SOD1) in cerebrospinal fluid of patients with recent-onset schizophrenia. Mol Psychiatry (2012) 0.92

Psychosis prediction: stratification of risk estimation with information-processing and premorbid functioning variables. Schizophr Bull (2013) 0.92

AKT1 moderation of cannabis-induced cognitive alterations in psychotic disorder. Neuropsychopharmacology (2011) 0.92

Minor physical anomalies and vulnerability in prodromal youth. Schizophr Res (2011) 0.91

Psychotropic medication use in youth at high risk for psychosis: comparison of baseline data from two research cohorts 1998-2005 and 2008-2011. Schizophr Res (2013) 0.90

Converging levels of analysis on a genomic hotspot for psychosis: insights from 22q11.2 deletion syndrome. Neuropharmacology (2012) 0.89

Cognition in schizophrenia: Past, present, and future. Schizophr Res Cogn (2014) 0.88

"Attenuated psychotic symptoms syndrome" as a risk syndrome of psychosis, diagnosis in DSM-V: The debate. Indian J Psychiatry (2011) 0.88

Improvements in negative symptoms and functional outcome after a new generation cognitive remediation program: a randomized controlled trial. Schizophr Bull (2013) 0.87

Predicting the risk of psychosis onset: advances and prospects. Early Interv Psychiatry (2012) 0.87

Neurocognitive and clinical predictors of long-term outcome in adolescents at ultra-high risk for psychosis: a 6-year follow-up. PLoS One (2014) 0.86

Cognitive interventions targeting brain plasticity in the prodromal and early phases of schizophrenia. Annu Rev Clin Psychol (2013) 0.86

Mismatch and lexical retrieval gestures are associated with visual information processing, verbal production, and symptomatology in youth at high risk for psychosis. Schizophr Res (2014) 0.86

The effect of neurogranin on neural correlates of episodic memory encoding and retrieval. Schizophr Bull (2011) 0.86

Abnormalities of the corpus callosum in non-psychotic high-risk offspring of schizophrenia patients. Psychiatry Res (2010) 0.85

Neurocognitive functioning in schizophrenia and during the early phases of psychosis: targeting cognitive remediation interventions. Biomed Res Int (2013) 0.85

Auditory working memory impairments in individuals at familial high risk for schizophrenia. Neuropsychology (2012) 0.84

Correspondence between psychometric and clinical high risk for psychosis in an undergraduate population. Psychol Assess (2014) 0.84

Social Cognition in Individuals at Ultra-High Risk for Psychosis: A Meta-Analysis. PLoS One (2015) 0.83

Assessing the potential to use neurocognition to predict who is at risk for developing bipolar disorder: a review of the literature. Cogn Neuropsychiatry (2012) 0.82

Emotion recognition deficits as predictors of transition in individuals at clinical high risk for schizophrenia: a neurodevelopmental perspective. Psychol Med (2015) 0.82

Cognitive functioning in first-episode schizophrenia: MATRICS Consensus Cognitive Battery (MCCB) Profile of Impairment. Schizophr Res (2014) 0.82

Computational neuropsychiatry - schizophrenia as a cognitive brain network disorder. Front Psychiatry (2014) 0.82

Ultra high risk status and transition to psychosis in 22q11.2 deletion syndrome. World Psychiatry (2016) 0.82

The Role of Cognition and Social Functioning as Predictors in the Transition to Psychosis for Youth With Attenuated Psychotic Symptoms. Schizophr Bull (2016) 0.82

Alterations in brain structures underlying language function in young adults at high familial risk for schizophrenia. Schizophr Res (2012) 0.82

Informed consent in the psychosis prodrome: ethical, procedural and cultural considerations. Philos Ethics Humanit Med (2014) 0.82

Pupillometer-Based Neurofeedback Cognitive Training to Improve Processing Speed and Social Functioning in Individuals at Clinical High Risk for Psychosis. Psychiatr Rehabil J (2016) 0.82

Association of Neurocognition With Transition to Psychosis: Baseline Functioning in the Second Phase of the North American Prodrome Longitudinal Study. JAMA Psychiatry (2016) 0.82

Gsx1 expression defines neurons required for prepulse inhibition. Mol Psychiatry (2014) 0.81

Change in neuropsychological functioning over one year in youth at clinical high risk for psychosis. Schizophr Res (2013) 0.81

Abnormal resting state FMRI activity predicts processing speed deficits in first-episode psychosis. Neuropsychopharmacology (2015) 0.81

Psychosis prediction and clinical utility in familial high-risk studies: selective review, synthesis, and implications for early detection and intervention. Early Interv Psychiatry (2013) 0.81

Physical activity level and medial temporal health in youth at ultra high-risk for psychosis. J Abnorm Psychol (2013) 0.81

The effect of odor valence on olfactory performance in schizophrenia patients, unaffected relatives and at-risk youth. J Psychiatr Res (2013) 0.80

Neurocognition and Duration of Psychosis: A 10-year Follow-up of First-Episode Patients. Schizophr Bull (2015) 0.80

Brain structure and function correlates of cognitive subtypes in schizophrenia. Psychiatry Res (2015) 0.80

Prevention of the first episode of psychosis. Psychiatr Clin North Am (2010) 0.80

Contributions of Feature Binding During Encoding and Functional Connectivity of the Medial Temporal Lobe Structures to Episodic Memory Deficits Across the Prodromal and First-Episode Phases of Schizophrenia. Clin Psychol Sci (2015) 0.79

Ten year neurocognitive trajectories in first-episode psychosis. Front Hum Neurosci (2013) 0.79

Maternal-fetal blood incompatibility and neuromorphologic anomalies in schizophrenia: Preliminary findings. Prog Neuropsychopharmacol Biol Psychiatry (2011) 0.79

Developmental mechanisms in the prodrome to psychosis. Dev Psychopathol (2013) 0.79

Striatal abnormalities and spontaneous dyskinesias in non-clinical psychosis. Schizophr Res (2013) 0.78

The impact of psychosis on the course of cognition: a prospective, nested case-control study in individuals at clinical high-risk for psychosis. Psychol Med (2015) 0.78

Prodromal Symptom Severity Predicts Accelerated Gray Matter Reduction and Third Ventricle Expansion Among Clinically High Risk Youth Developing Psychotic Disorders. Mol Neuropsychiatry (2015) 0.78

Identifying children and adolescents at ultra high risk of psychosis in Italian neuropsychiatry services: a feasibility study. Eur Child Adolesc Psychiatry (2015) 0.78

Contributions of experimental psychiatry to research on the psychosis prodrome. Front Psychiatry (2013) 0.78

Healthy adolescent performance on the MATRICS Consensus Cognitive Battery (MCCB): Developmental data from two samples of volunteers. Schizophr Res (2016) 0.77

Neuropsychological functioning in childhood-onset psychosis and attention-deficit/hyperactivity disorder. J Child Psychol Psychiatry (2014) 0.77

Cognitive changes following antidepressant or antipsychotic treatment in adolescents at clinical risk for psychosis. Schizophr Res (2012) 0.77

The Course and Correlates of Everyday Functioning in Schizophrenia. Schizophr Res Cogn (2014) 0.77

Motor agency: a new and highly sensitive measure to reveal agency disturbances in early psychosis. PLoS One (2012) 0.77

Association between Dopamine Receptor D2 (DRD2) Variations rs6277 and rs1800497 and Cognitive Performance According to Risk Type for Psychosis: A Nested Case Control Study in a Finnish Population Sample. PLoS One (2015) 0.77

Neuropsychological Impairment in Prodromal, First-Episode, and Chronic Psychosis: Assessing RBANS Performance. PLoS One (2015) 0.76

Luria revisited: cognitive research in schizophrenia, past implications and future challenges. Philos Ethics Humanit Med (2015) 0.76

Niacin Skin Sensitivity Is Increased in Adolescents at Ultra-High Risk for Psychosis. PLoS One (2016) 0.76

Various neurocognitive deficits and conversion risk in individuals at clinical high risk for psychosis. Early Interv Psychiatry (2015) 0.76

Sequence of Molecular Events during the Maturation of the Developing Mouse Prefrontal Cortex. Mol Neuropsychiatry (2015) 0.76

Different vulnerability indicators for psychosis and their neuropsychological characteristics in the Northern Finland 1986 Birth Cohort. J Clin Exp Neuropsychol (2011) 0.76

Primary prevention of psychosis through interventions in the symptomatic prodromal phase, a pragmatic Norwegian Ultra High Risk study. BMC Psychiatry (2015) 0.76

A developmental look at the attentional system in the at risk and first episode of psychosis: age related changes in attention along the psychosis spectrum. Cogn Neuropsychiatry (2012) 0.76

Neuropsychological profile according to the clinical stage of young persons presenting for mental health care. BMC Psychol (2013) 0.76

Cognitive impairment in schizophrenia across age groups: a case-control study. BMC Psychiatry (2016) 0.75

A case report of cognitive behavioural therapy for social anxiety in an ultra-high risk patient. Early Interv Psychiatry (2013) 0.75

Development of abbreviated eight-item form of the Penn Verbal Reasoning Test. Assessment (2014) 0.75

Nicotine usage is associated with elevated processing speed, spatial working memory, and visual learning performance in youth at ultrahigh-risk for psychosis. Psychiatry Res (2014) 0.75

Challenges in the early detection and intervention of the psychosis-risk syndrome. Shanghai Arch Psychiatry (2015) 0.75

Articles cited by this

Missing data: our view of the state of the art. Psychol Methods (2002) 42.97

The endophenotype concept in psychiatry: etymology and strategic intentions. Am J Psychiatry (2003) 21.70

What are the functional consequences of neurocognitive deficits in schizophrenia? Am J Psychiatry (1996) 11.03

Prediction of psychosis in youth at high clinical risk: a multisite longitudinal study in North America. Arch Gen Psychiatry (2008) 9.54

Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence. Mol Psychiatry (2005) 9.23

Neurocognitive deficit in schizophrenia: a quantitative review of the evidence. Neuropsychology (1998) 8.73

Prodromal assessment with the structured interview for prodromal syndromes and the scale of prodromal symptoms: predictive validity, interrater reliability, and training to reliability. Schizophr Bull (2003) 7.11

Diagnosing schizophrenia in the initial prodromal phase. Arch Gen Psychiatry (2001) 5.35

Identification of separable cognitive factors in schizophrenia. Schizophr Res (2004) 5.34

Prospective diagnosis of the initial prodrome for schizophrenia based on the Structured Interview for Prodromal Syndromes: preliminary evidence of interrater reliability and predictive validity. Am J Psychiatry (2002) 4.60

A clinical approach for the diagnosis of diabetes mellitus: an analysis using glycosylated hemoglobin levels. Meta-analysis Research Group on the Diagnosis of Diabetes Using Glycated Hemoglobin Levels. JAMA (1996) 3.66

Cognitive deficits in unaffected first-degree relatives of schizophrenia patients: a meta-analytic review of putative endophenotypes. Schizophr Bull (2005) 3.36

North American Prodrome Longitudinal Study: a collaborative multisite approach to prodromal schizophrenia research. Schizophr Bull (2007) 3.28

Neurocognition in first-episode schizophrenia: a meta-analytic review. Neuropsychology (2009) 3.27

Premorbid IQ in schizophrenia: a meta-analytic review. Am J Psychiatry (2008) 3.27

The prodromal phase of first-episode psychosis: past and current conceptualizations. Schizophr Bull (1996) 3.07

Validity of the prodromal risk syndrome for first psychosis: findings from the North American Prodrome Longitudinal Study. Schizophr Bull (2009) 2.90

The schizophrenia prodrome revisited: a neurodevelopmental perspective. Schizophr Bull (2003) 2.67

The Continuous Performance Test, identical pairs version (CPT-IP): I. New findings about sustained attention in normal families. Psychiatry Res (1988) 2.61

Cognitive deficits in relatives of patients with schizophrenia: a meta-analysis. Schizophr Res (2004) 2.61

The Consortium on the Genetics of Schizophrenia: neurocognitive endophenotypes. Schizophr Bull (2006) 2.53

Information processing and attentional functioning in the developmental course of schizophrenic disorders. Schizophr Bull (1984) 2.48

Generalized and specific neurocognitive deficits in prodromal schizophrenia. Biol Psychiatry (2005) 2.43

Impact of the National Breast and Cervical Cancer Early Detection Program on mammography and Pap test utilization among white, Hispanic, and African American women: 1996-2000. Cancer (2007) 2.29

The pathophysiology of schizophrenia disorders: perspectives from the spectrum. Am J Psychiatry (2004) 1.91

Early detection and intervention with schizophrenia: rationale. Schizophr Bull (1996) 1.86

Memory impairments identified in people at ultra-high risk for psychosis who later develop first-episode psychosis. Am J Psychiatry (2005) 1.84

A longitudinal study of neurocognitive function in individuals at-risk for psychosis. Schizophr Res (2006) 1.81

Neurocognitive performance and functional disability in the psychosis prodrome. Schizophr Res (2006) 1.67

Impairment of olfactory identification ability in individuals at ultra-high risk for psychosis who later develop schizophrenia. Am J Psychiatry (2003) 1.67

Cure therapeutics and strategic prevention: raising the bar for mental health research. Mol Psychiatry (2006) 1.64

Childhood developmental abnormalities in schizophrenia: evidence from high-risk studies. Schizophr Res (2003) 1.60

Neuropsychological risk indicators for schizophrenia: a review of family studies. Schizophr Bull (1994) 1.55

Generalized and specific cognitive performance in clinical high-risk cohorts: a review highlighting potential vulnerability markers for psychosis. Schizophr Bull (2006) 1.54

Neuropsychological change in young people at high risk for schizophrenia: results from the first two neuropsychological assessments of the Edinburgh High Risk Study. Psychol Med (2000) 1.52

Neuropsychological status of subjects at high risk for a first episode of psychosis. Schizophr Res (2004) 1.42

The course of neurocognition and social functioning in individuals at ultra high risk for psychosis. Schizophr Bull (2007) 1.40

Left hippocampal volume as a vulnerability indicator for schizophrenia: a magnetic resonance imaging morphometric study of nonpsychotic first-degree relatives. Arch Gen Psychiatry (2002) 1.38

Neurocognitive indicators for a conversion to psychosis: comparison of patients in a potentially initial prodromal state who did or did not convert to a psychosis. Schizophr Res (2007) 1.38

Altered brain activation in dorsolateral prefrontal cortex in adolescents and young adults at genetic risk for schizophrenia: an fMRI study of working memory. Schizophr Res (2006) 1.35

Spatial working memory ability is a marker of risk-for-psychosis. Psychol Med (2003) 1.32

Neurocognitive deficits in the (putative) prodrome and first episode of psychosis. Schizophr Res (2007) 1.29

Cognitive performance in schizophrenia patients assessed before and following the first psychotic episode. Schizophr Res (2003) 1.26

Neuropsychological functioning in adolescents and young adults at genetic risk for schizophrenia and affective psychoses: results from the Harvard and Hillside Adolescent High Risk Studies. Schizophr Bull (2006) 1.26

Course of neurocognitive deficits in the prodrome and first episode of schizophrenia. Neuropsychology (2010) 1.22

The New York high risk project to the Hillside recognition and prevention (RAP) program. Am J Med Genet (2002) 1.21

Neuropsychological course in the prodrome and first episode of psychosis: findings from the PRIME North America Double Blind Treatment Study. Schizophr Res (2008) 1.20

Clinical and genetic high-risk strategies in understanding vulnerability to psychosis. Schizophr Res (2005) 1.16

An independent analysis of the Copenhagen sample of the Danish adoption study of schizophrenia. II. The relationship between schizotypal personality disorder and schizophrenia. Arch Gen Psychiatry (1981) 1.14

Schizophrenia and brain dysfunction: an integration of recent neurodiagnostic findings. Psychol Bull (1983) 1.13

Subjective and objective neuropsychological abnormalities in a psychosis prodrome clinic. Br J Psychiatry Suppl (2002) 1.13

Tests of executive functions in first-degree relatives of schizophrenic patients: a meta-analysis. Psychol Med (2005) 1.11

Neurocognitive functioning in subjects at risk for a first episode of psychosis compared with first- and multiple-episode schizophrenia. J Clin Exp Neuropsychol (2006) 1.10

Spatial working memory deficits in adolescents at clinical high risk for schizophrenia. Schizophr Res (2006) 1.06

Perceptual organization in first episode schizophrenia and ultra-high-risk states. Schizophr Res (2006) 1.06

Sustained attention in young people at high risk of psychosis does not predict transition to psychosis. Schizophr Res (2005) 1.02

Global attentional deviance as a marker of risk for schizophrenia: specificity and predictive validity. J Abnorm Psychol (1985) 1.02

Cognitive functions in prepsychotic patients. Prog Neuropsychopharmacol Biol Psychiatry (2005) 1.01

Neuropsychological deficits in individuals with an at risk mental state for psychosis - working memory as a potential trait marker. Schizophr Res (2007) 0.98

Neuropsychological and neurophysiological findings in individuals suspected to be at risk for schizophrenia: preliminary results from the Basel early detection of psychosis study - Früherkennung von Psychosen (FEPSY). Acta Psychiatr Scand (2003) 0.97

Memory tests in first-degree adult relatives of schizophrenic patients: a meta-analysis. Schizophr Res (2005) 0.96

Visual form perception: a comparison of individuals at high risk for psychosis, recent onset schizophrenia and chronic schizophrenia. Schizophr Res (2007) 0.91

The Palau Early Psychosis Study: neurocognitive functioning in high-risk adolescents. Schizophr Res (2006) 0.86

Fine motor function and neuropsychological deficits in individuals at risk for schizophrenia. Eur Arch Psychiatry Clin Neurosci (2005) 0.85

The neuropsychology of schizophrenia: a neurodevelopmental and case study approach. J Neuropsychiatry Clin Neurosci (1990) 0.81

Articles by these authors

Effectiveness of antipsychotic drugs in patients with chronic schizophrenia. N Engl J Med (2005) 28.99

Research domain criteria (RDoC): toward a new classification framework for research on mental disorders. Am J Psychiatry (2010) 16.89

Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study. Lancet (2009) 12.96

Prediction of psychosis in youth at high clinical risk: a multisite longitudinal study in North America. Arch Gen Psychiatry (2008) 9.54

The MATRICS Consensus Cognitive Battery, part 1: test selection, reliability, and validity. Am J Psychiatry (2008) 9.00

Prodromal assessment with the structured interview for prodromal syndromes and the scale of prodromal symptoms: predictive validity, interrater reliability, and training to reliability. Schizophr Bull (2003) 7.11

Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia. Am J Hum Genet (2003) 6.63

Practice guideline for the treatment of patients with schizophrenia, second edition. Am J Psychiatry (2004) 6.40

Microduplications of 16p11.2 are associated with schizophrenia. Nat Genet (2009) 6.13

Hyperactivity and hyperconnectivity of the default network in schizophrenia and in first-degree relatives of persons with schizophrenia. Proc Natl Acad Sci U S A (2009) 6.09

Persistent cannabis users show neuropsychological decline from childhood to midlife. Proc Natl Acad Sci U S A (2012) 5.67

Neurocognitive effects of antipsychotic medications in patients with chronic schizophrenia in the CATIE Trial. Arch Gen Psychiatry (2007) 5.64

A genome-wide investigation of SNPs and CNVs in schizophrenia. PLoS Genet (2009) 5.01

A summary of the FDA-NIMH-MATRICS workshop on clinical trial design for neurocognitive drugs for schizophrenia. Schizophr Bull (2005) 4.66

Prospective diagnosis of the initial prodrome for schizophrenia based on the Structured Interview for Prodromal Syndromes: preliminary evidence of interrater reliability and predictive validity. Am J Psychiatry (2002) 4.60

Approaching a consensus cognitive battery for clinical trials in schizophrenia: the NIMH-MATRICS conference to select cognitive domains and test criteria. Biol Psychiatry (2004) 4.46

Randomized, double-blind trial of olanzapine versus placebo in patients prodromally symptomatic for psychosis. Am J Psychiatry (2006) 4.18

The psychosis high-risk state: a comprehensive state-of-the-art review. JAMA Psychiatry (2013) 4.16

Mapping cortical change in Alzheimer's disease, brain development, and schizophrenia. Neuroimage (2004) 4.13

Effectiveness of clozapine versus olanzapine, quetiapine, and risperidone in patients with chronic schizophrenia who did not respond to prior atypical antipsychotic treatment. Am J Psychiatry (2006) 4.12

The MATRICS Consensus Cognitive Battery, part 2: co-norming and standardization. Am J Psychiatry (2008) 4.02

Cognition in schizophrenia: summary Nice Consultation Meeting 2012. Eur Neuropsychopharmacol (2013) 3.99

Antipsychotic drug effects on brain morphology in first-episode psychosis. Arch Gen Psychiatry (2005) 3.78

Cost-effectiveness of second-generation antipsychotics and perphenazine in a randomized trial of treatment for chronic schizophrenia. Am J Psychiatry (2006) 3.72

At clinical high risk for psychosis: outcome for nonconverters. Am J Psychiatry (2011) 3.66

The Collaborative Longitudinal Personality Disorders Study (CLPS): overview and implications. J Pers Disord (2005) 3.51

Plausibility and possible determinants of sudden "remissions" in borderline patients. Psychiatry (2003) 3.29

Functional co-primary measures for clinical trials in schizophrenia: results from the MATRICS Psychometric and Standardization Study. Am J Psychiatry (2008) 3.29

North American Prodrome Longitudinal Study: a collaborative multisite approach to prodromal schizophrenia research. Schizophr Bull (2007) 3.28

Neurocognition in first-episode schizophrenia: a meta-analytic review. Neuropsychology (2009) 3.27

Premorbid IQ in schizophrenia: a meta-analytic review. Am J Psychiatry (2008) 3.27

Effects of olanzapine, quetiapine, and risperidone on neurocognitive function in early psychosis: a randomized, double-blind 52-week comparison. Am J Psychiatry (2007) 3.21

Schizophrenia is a cognitive illness: time for a change in focus. JAMA Psychiatry (2013) 3.16

Preliminary findings for two new measures of social and role functioning in the prodromal phase of schizophrenia. Schizophr Bull (2007) 3.15

Association between a functional catechol O-methyltransferase gene polymorphism and schizophrenia: meta-analysis of case-control and family-based studies. Am J Psychiatry (2003) 3.12

Effectiveness of olanzapine, quetiapine, risperidone, and ziprasidone in patients with chronic schizophrenia following discontinuation of a previous atypical antipsychotic. Am J Psychiatry (2006) 3.12

Static and dynamic cognitive deficits in childhood preceding adult schizophrenia: a 30-year study. Am J Psychiatry (2010) 3.05

Functional impairment in patients with schizotypal, borderline, avoidant, or obsessive-compulsive personality disorder. Am J Psychiatry (2002) 2.99

Beyond hypofrontality: a quantitative meta-analysis of functional neuroimaging studies of working memory in schizophrenia. Hum Brain Mapp (2005) 2.93

Initial heritability analyses of endophenotypic measures for schizophrenia: the consortium on the genetics of schizophrenia. Arch Gen Psychiatry (2007) 2.91

Validity of the prodromal risk syndrome for first psychosis: findings from the North American Prodrome Longitudinal Study. Schizophr Bull (2009) 2.90

Prescription practices in the treatment of first-episode schizophrenia spectrum disorders: data from the national RAISE-ETP study. Am J Psychiatry (2014) 2.81

Effects of antipsychotic medications on psychosocial functioning in patients with chronic schizophrenia: findings from the NIMH CATIE study. Am J Psychiatry (2007) 2.75

Baseline neurocognitive deficits in the CATIE schizophrenia trial. Neuropsychopharmacology (2006) 2.70

Effectiveness of olanzapine, quetiapine, and risperidone in patients with chronic schizophrenia after discontinuing perphenazine: a CATIE study. Am J Psychiatry (2007) 2.68

Adolescent alcohol use is a risk factor for adult alcohol and drug dependence: evidence from a twin design. Psychol Med (2005) 2.66

The HMG-CoA reductase inhibitor lovastatin reverses the learning and attention deficits in a mouse model of neurofibromatosis type 1. Curr Biol (2005) 2.62

Social cognition in schizophrenia: an NIMH workshop on definitions, assessment, and research opportunities. Schizophr Bull (2008) 2.59

Hypomethylation of MB-COMT promoter is a major risk factor for schizophrenia and bipolar disorder. Hum Mol Genet (2006) 2.53

Neuropsychological decline in schizophrenia from the premorbid to the postonset period: evidence from a population-representative longitudinal study. Am J Psychiatry (2014) 2.51

Risk and protection in prodromal schizophrenia: ethical implications for clinical practice and future research. Schizophr Bull (2005) 2.50

Generalized and specific neurocognitive deficits in prodromal schizophrenia. Biol Psychiatry (2005) 2.43

Three potential susceptibility loci shown by a genome-wide scan for regions influencing the age at onset of mania. Am J Psychiatry (2004) 2.40

Hypermethylation of the reelin (RELN) promoter in the brain of schizophrenic patients: a preliminary report. Am J Med Genet B Neuropsychiatr Genet (2005) 2.34

Ten-year course of borderline personality disorder: psychopathology and function from the Collaborative Longitudinal Personality Disorders study. Arch Gen Psychiatry (2011) 2.33

Amygdala hyperreactivity in borderline personality disorder: implications for emotional dysregulation. Biol Psychiatry (2003) 2.31

Comparative gene expression analysis of blood and brain provides concurrent validation of SELENBP1 up-regulation in schizophrenia. Proc Natl Acad Sci U S A (2005) 2.29

Hierarchical genetic organization of human cortical surface area. Science (2012) 2.28

Efficacy and tolerability of olanzapine, quetiapine, and risperidone in the treatment of early psychosis: a randomized, double-blind 52-week comparison. Am J Psychiatry (2007) 2.22

Axis I and axis II disorders as predictors of prospective suicide attempts: findings from the collaborative longitudinal personality disorders study. J Abnorm Psychol (2003) 2.17

Cognitive effects of atypical antipsychotic medications in patients with Alzheimer's disease: outcomes from CATIE-AD. Am J Psychiatry (2011) 2.15

Psychiatric disorders from childhood to adulthood in 22q11.2 deletion syndrome: results from the International Consortium on Brain and Behavior in 22q11.2 Deletion Syndrome. Am J Psychiatry (2014) 2.15

Identification and treatment of a pineal region tumor in an adolescent with prodromal psychotic symptoms. Am J Psychiatry (2010) 2.12