Validity of the prodromal risk syndrome for first psychosis: findings from the North American Prodrome Longitudinal Study.

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Published in Schizophr Bull on April 21, 2009

Authors

Scott W Woods1, Jean Addington, Kristin S Cadenhead, Tyrone D Cannon, Barbara A Cornblatt, Robert Heinssen, Diana O Perkins, Larry J Seidman, Ming T Tsuang, Elaine F Walker, Thomas H McGlashan

Author Affiliations

1: PRIME Prodromal Research Clinic, Department of Psychiatry, Yale University School of Medicine, 34 Park Street, New Haven, CT 06519, USA. scott.woods@yale.edu

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Psychosocial treatment for first-episode psychosis: a research update. Am J Psychiatry (2005) 2.03

A randomized clinical trial of MK-0777 for the treatment of cognitive impairments in people with schizophrenia. Biol Psychiatry (2010) 1.99

Progressive brain structural changes mapped as psychosis develops in 'at risk' individuals. Schizophr Res (2009) 1.98

Implications for the neural basis of social cognition for the study of schizophrenia. Am J Psychiatry (2003) 1.98

Stability of functional impairment in patients with schizotypal, borderline, avoidant, or obsessive-compulsive personality disorder over two years. Psychol Med (2005) 1.97

Two-year stability and change of schizotypal, borderline, avoidant, and obsessive-compulsive personality disorders. J Consult Clin Psychol (2004) 1.96