Published in Mol Immunol on May 26, 2010
Proteolytic networks in cancer. Trends Cell Biol (2011) 2.10
PAR2 absence completely rescues inflammation and ichthyosis caused by altered CAP1/Prss8 expression in mouse skin. Nat Commun (2011) 1.09
Systems-level analysis of proteolytic events in increased vascular permeability and complement activation in skin inflammation. Sci Signal (2013) 1.06
Identification and function of proteolysis regulators in seminal fluid. Mol Reprod Dev (2012) 1.02
PAR1 contributes to influenza A virus pathogenicity in mice. J Clin Invest (2012) 1.00
Proteinase 3-dependent caspase-3 cleavage modulates neutrophil death and inflammation. J Clin Invest (2014) 0.95
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JNK2 promotes endothelial cell alignment under flow. PLoS One (2011) 0.89
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Amblyomma americanum tick saliva serine protease inhibitor 6 is a cross-class inhibitor of serine proteases and papain-like cysteine proteases that delays plasma clotting and inhibits platelet aggregation. Insect Mol Biol (2013) 0.84
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Inhibition of neutrophil elastase attenuates airway hyperresponsiveness and inflammation in a mouse model of secondary allergen challenge: neutrophil elastase inhibition attenuates allergic airway responses. Respir Res (2013) 0.83
Optimization of N-benzoylindazole derivatives as inhibitors of human neutrophil elastase. J Med Chem (2013) 0.82
Tryptogalinin is a tick Kunitz serine protease inhibitor with a unique intrinsic disorder. PLoS One (2013) 0.80
Using the water signal to detect invisible exchanging protons in the catalytic triad of a serine protease. J Biomol NMR (2011) 0.80
Mast Cell Proteases and Inflammation. Drug Discov Today Dis Models (2011) 0.80
Neonatal phytoestrogen exposure alters oviduct mucosal immune response to pregnancy and affects preimplantation embryo development in the mouse. Biol Reprod (2012) 0.79
Cathepsin G induces cell aggregation of human breast cancer MCF-7 cells via a 2-step mechanism: catalytic site-independent binding to the cell surface and enzymatic activity-dependent induction of the cell aggregation. Mediators Inflamm (2012) 0.79
A monoclonal antibody (MCPR3-7) interfering with the activity of proteinase 3 by an allosteric mechanism. J Biol Chem (2013) 0.79
Profiling spermatogenic failure in adult testes bearing Sox9-deficient Sertoli cells identifies genes involved in feminization, inflammation and stress. Reprod Biol Endocrinol (2010) 0.78
Molecular characterization of serine protease inhibitor isoform 3, SmSPI, from Schistosoma mansoni. Parasitol Res (2016) 0.76
Involvement of Kallikrein-Related Peptidases in Normal and Pathologic Processes. Dis Markers (2015) 0.76
Cinnoline derivatives as human neutrophil elastase inhibitors. J Enzyme Inhib Med Chem (2015) 0.76
Global endometrial transcriptomic profiling: transient immune activation precedes tissue proliferation and repair in healthy beef cows. BMC Genomics (2012) 0.76
Alpha-1 antitrypsin is markedly decreased following pulmonary F. tularensis challenge. Front Cell Infect Microbiol (2011) 0.76
Reciprocal modulation of surface expression of annexin A2 in a human umbilical vein endothelial cell-derived cell line by eicosapentaenoic acid and docosahexaenoic acid. PLoS One (2014) 0.76
The interplay of extracellular matrix and microbiome in urothelial bladder cancer. Nat Rev Urol (2015) 0.76
Protease-activated receptor 4 deficiency offers cardioprotection after acute ischemia reperfusion injury. J Mol Cell Cardiol (2015) 0.76
Selective depletion of tumour suppressors Deleted in Colorectal Cancer (DCC) and neogenin by environmental and endogenous serine proteases: linking diet and cancer. BMC Cancer (2016) 0.75
Plasma levels of alpha-1-antichymotrypsin are elevated in patients with chronic heart failure, but are of limited prognostic value. Neth Heart J (2014) 0.75
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Ecotin-like ISP of L. major promastigotes fine-tunes macrophage phagocytosis by limiting the pericellular release of bradykinin from surface-bound kininogens: a survival strategy based on the silencing of proinflammatory G-protein coupled kinin B2 and B1 receptors. Mediators Inflamm (2014) 0.75
Human lymph-node CD8(+) T cells display an altered phenotype during systemic autoimmunity. Clin Transl Immunology (2016) 0.75
Purification and Characterization of a Novel Kazal-Type Trypsin Inhibitor from the Leech of Hirudinaria manillensis. Toxins (Basel) (2016) 0.75
Comparison between the collagen intensity and mast cell density in the lingual muscles and myocardium of autopsied chronic chagasic and nonchagasic patients. Parasitol Res (2012) 0.75
Effects of the neutrophil elastase inhibitor EL-17 in rat adjuvant-induced arthritis. Rheumatology (Oxford) (2016) 0.75
Synthesis and Pharmacological Evaluation of Indole Derivatives as Deaza Analogues of Potent Human Neutrophil Elastase Inhibitors. Drug Dev Res (2016) 0.75
Insulin-like growth factor-1 signaling is responsible for cathepsin G-induced aggregation of breast cancer MCF-7 cells. Cancer Sci (2017) 0.75
Fungal biomarker discovery by integration of classifiers. BMC Genomics (2017) 0.75
Characterization of new human CD20 monoclonal antibodies with potent cytolytic activity against non-Hodgkin lymphomas. Blood (2004) 3.38
Hereditary and acquired angioedema: problems and progress: proceedings of the third C1 esterase inhibitor deficiency workshop and beyond. J Allergy Clin Immunol (2004) 3.07
Elevated nucleosome levels in systemic inflammation and sepsis. Crit Care Med (2003) 2.76
Human CD8(+) T-cell differentiation in response to viruses. Nat Rev Immunol (2003) 2.23
Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences. Blood (2013) 2.14
IL-7 receptor alpha chain expression distinguishes functional subsets of virus-specific human CD8+ T cells. Blood (2005) 1.95
Emergence of a CD4+CD28- granzyme B+, cytomegalovirus-specific T cell subset after recovery of primary cytomegalovirus infection. J Immunol (2004) 1.89
Inflammatory markers in AD and MCI patients with different biomarker profiles. Neurobiol Aging (2008) 1.82
Hyposplenism: comparison of different methods for determining splenic function. Am J Hematol (2012) 1.69
Activation of protein C following infusion of protein C concentrate in children with severe meningococcal sepsis and purpura fulminans: a randomized, double-blinded, placebo-controlled, dose-finding study. Crit Care Med (2003) 1.68
Cell-derived microparticles in synovial fluid from inflamed arthritic joints support coagulation exclusively via a factor VII-dependent mechanism. Arthritis Rheum (2002) 1.67
Disseminated intravascular coagulation in sepsis. Chest (2005) 1.64
Serum levels of mannose-binding lectin and the risk of future coronary artery disease in apparently healthy men and women. Arterioscler Thromb Vasc Biol (2006) 1.62
C-reactive protein and the risk of cardiovascular mortality. Am J Med (2003) 1.62
Rapid CD8+ T cell repertoire focusing and selection of high-affinity clones into memory following primary infection with a persistent human virus: human cytomegalovirus. J Immunol (2007) 1.56
Differential usage of cellular niches by cytomegalovirus versus EBV- and influenza virus-specific CD8+ T cells. J Immunol (2006) 1.55
Anti-inflammatory effects of a p38 mitogen-activated protein kinase inhibitor during human endotoxemia. J Immunol (2002) 1.51
Molecular profiling of cytomegalovirus-induced human CD8+ T cell differentiation. J Clin Invest (2010) 1.50
CMV-specific CD8+ T-cell function is not impaired in chronic lymphocytic leukemia. Blood (2013) 1.49
Functional characterization of the lectin pathway of complement in human serum. Mol Immunol (2003) 1.48
c-ANCA as a serological pitfall. Lancet (2004) 1.46
Self-administration of C1-inhibitor concentrate in patients with hereditary or acquired angioedema caused by C1-inhibitor deficiency. J Allergy Clin Immunol (2006) 1.46
CD27 defines phenotypically and functionally different human NK cell subsets. J Immunol (2008) 1.44
Sticky signaling--adhesion class G protein-coupled receptors take the stage. Sci Signal (2013) 1.42
Cytomegalovirus infection reduces telomere length of the circulating T cell pool. J Immunol (2010) 1.42
Strong selection of virus-specific cytotoxic CD4+ T-cell clones during primary human cytomegalovirus infection. Blood (2006) 1.40
Hemostatic markers in healthy postmenopausal women during intranasal and oral hormone therapy: a randomized trial. Menopause (2008) 1.39
The epidermal growth factor-like domains of the human EMR2 receptor mediate cell attachment through chondroitin sulfate glycosaminoglycans. Blood (2003) 1.37
C-reactive protein levels and coronary artery disease incidence and mortality in apparently healthy men and women: the EPIC-Norfolk prospective population study 1993-2003. Atherosclerosis (2005) 1.36
Complement-mediated ischemia-reperfusion injury: lessons learned from animal and clinical studies. Ann Surg (2009) 1.36
IL-8 plasma concentrations and the risk of future coronary artery disease in apparently healthy men and women: the EPIC-Norfolk prospective population study. Arterioscler Thromb Vasc Biol (2004) 1.35
Recombinant human C1-inhibitor for the treatment of acute angioedema attacks in patients with hereditary angioedema. J Allergy Clin Immunol (2010) 1.35
CD103 is a marker for alloantigen-induced regulatory CD8+ T cells. J Immunol (2006) 1.33
Clinical and immunologic aspects of cytomegalovirus infection in solid organ transplant recipients. Transplantation (2005) 1.33
AUC-guided dosing of tacrolimus prevents progressive systemic overexposure in renal transplant recipients. Kidney Int (2005) 1.30
The EGF-TM7 family: a postgenomic view. Immunogenetics (2003) 1.27
Human virus-specific CD8+ T cells: diversity specialists. Immunol Rev (2006) 1.24
F4/80 and the related adhesion-GPCRs. Eur J Immunol (2011) 1.20
Granzyme B, a novel mediator of allergic inflammation: its induction and release in blood basophils and human asthma. Blood (2006) 1.19
Properties of CD4(+) T cells in human cytomegalovirus infection. Hum Immunol (2004) 1.17
Rapamycin does not induce anergy but inhibits expansion and differentiation of alloreactive human T cells. Transplantation (2006) 1.16
GITR triggering induces expansion of both effector and regulatory CD4+ T cells in vivo. J Immunol (2009) 1.15
Effectiveness of a 5-day external stenting protocol on urological complications after renal transplantation. World J Surg (2009) 1.14
The epidermal growth factor-seven transmembrane (EGF-TM7) receptor CD97 is required for neutrophil migration and host defense. J Immunol (2004) 1.14
C1-inhibitor in patients with severe sepsis and septic shock: beneficial effect on renal dysfunction. Crit Care Med (2002) 1.14
P-selectin- and CD63-exposing platelet microparticles reflect platelet activation in peripheral arterial disease and myocardial infarction. Clin Chem (2006) 1.13
The role of cytokines in activation of coagulation and fibrinolysis in dengue shock syndrome. Thromb Haemost (2002) 1.12
Differential expression of HIV-1 interfering factors in monocyte-derived macrophages stimulated with polarizing cytokines or interferons. Sci Rep (2012) 1.12
Expression levels of apoptosis-related proteins predict clinical outcome in anaplastic large cell lymphoma. Blood (2002) 1.11
Ligation of the adhesion-GPCR EMR2 regulates human neutrophil function. FASEB J (2007) 1.11
Elevated plasma levels of the long pentraxin, pentraxin 3, in severe dengue virus infections. J Med Virol (2005) 1.10
Expression and regulation of CD97 in colorectal carcinoma cell lines and tumor tissues. Am J Pathol (2002) 1.09
Advancement of mesenchymal stem cell therapy in solid organ transplantation (MISOT). Transplantation (2010) 1.07
TAFI and PAI-1 levels in human sepsis. Thromb Res (2005) 1.07
Serum levels of type II secretory phospholipase A2 and the risk of future coronary artery disease in apparently healthy men and women: the EPIC-Norfolk Prospective Population Study. Arterioscler Thromb Vasc Biol (2005) 1.06
Phenotyping primary human microglia: tight regulation of LPS responsiveness. Glia (2012) 1.06
Detection of a soluble form of BACE-1 in human cerebrospinal fluid by a sensitive activity assay. Clin Chem (2006) 1.05
Regulation of complement activation by C-reactive protein: targeting of the inhibitory activity of C4b-binding protein. J Immunol (2006) 1.05
Human mast cells produce and release the cytotoxic lymphocyte associated protease granzyme B upon activation. Mol Immunol (2007) 1.05
Evidence that complement protein C1q interacts with C-reactive protein through its globular head region. J Immunol (2006) 1.05
The human EGF-TM7 family member EMR2 is a heterodimeric receptor expressed on myeloid cells. J Leukoc Biol (2002) 1.04
Proteolytic cleavage of the EMR2 receptor requires both the extracellular stalk and the GPS motif. FEBS Lett (2003) 1.03
Expression of the inhibitory CD200 receptor is associated with alternative macrophage activation. J Innate Immun (2009) 1.03
Association of mannose-binding lectin genotype with cardiovascular abnormalities in Kawasaki disease. Lancet (2003) 1.02
Cytomegalovirus-induced effector T cells cause endothelial cell damage. Clin Vaccine Immunol (2012) 1.02
Molecular comparison of calcineurin inhibitor-induced fibrogenic responses in protocol renal transplant biopsies. J Am Soc Nephrol (2006) 1.02
Activated complement components and complement activator molecules on the surface of cell-derived microparticles in patients with rheumatoid arthritis and healthy individuals. Ann Rheum Dis (2007) 1.01
Human cytomegalovirus infection induces a rapid and sustained change in the expression of NK cell receptors on CD8+ T cells. J Immunol (2008) 1.01
Immune responses and prediction of major infection in patients undergoing transhiatal or transthoracic esophagectomy for cancer. Ann Surg (2003) 1.01
An unusual mode of concerted evolution of the EGF-TM7 receptor chimera EMR2. FASEB J (2006) 1.01
Cross-reactivity of cytomegalovirus-specific CD8+ T cells to allo-major histocompatibility complex class I molecules. Transplantation (2004) 1.01
Cytokine patterns during dengue shock syndrome. Eur Cytokine Netw (2003) 1.01
Administration of C1 inhibitor reduces neutrophil activation in patients with sepsis. Clin Diagn Lab Immunol (2003) 1.00
Expression of the largest CD97 and EMR2 isoforms on leukocytes facilitates a specific interaction with chondroitin sulfate on B cells. J Leukoc Biol (2004) 1.00
Systemic treatment with either cyclosporin A or methotrexate does not influence the T helper 1/T helper 2 balance in psoriatic patients. J Clin Immunol (2004) 1.00
Mouse Hobit is a homolog of the transcriptional repressor Blimp-1 that regulates NKT cell effector differentiation. Nat Immunol (2012) 0.99
Immune responsiveness in renal transplant recipients: mycophenolic acid severely depresses humoral immunity in vivo. Kidney Int (2002) 0.98
CSF neurofilaments in frontotemporal dementia compared with early onset Alzheimer's disease and controls. Dement Geriatr Cogn Disord (2007) 0.97
The human EGF-TM7 receptor EMR3 is a marker for mature granulocytes. J Leukoc Biol (2006) 0.97
Shear stress-dependent downregulation of the adhesion-G protein-coupled receptor CD97 on circulating leukocytes upon contact with its ligand CD55. J Immunol (2013) 0.97
Rituximab-induced elimination of acquired angioedema due to C1-inhibitor deficiency. Am J Med (2006) 0.96
Analysis of CD97 expression and manipulation: antibody treatment but not gene targeting curtails granulocyte migration. J Immunol (2008) 0.96
BACE1 activity in cerebrospinal fluid and its relation to markers of AD pathology. J Alzheimers Dis (2010) 0.95
Structural and functional aspects of C1-inhibitor. Immunobiology (2002) 0.95
Untreated rejection in 6-month protocol biopsies is not associated with fibrosis in serial biopsies or with loss of graft function. J Am Soc Nephrol (2006) 0.95
C-reactive protein activates complement in infarcted human myocardium. Am J Pathol (2003) 0.94
Alloantigen-induced regulatory CD8+CD103+ T cells. Hum Immunol (2008) 0.94
The value of estimated GFR in comparison to measured GFR for the assessment of renal function in adult patients with Fabry disease. Nephrol Dial Transplant (2010) 0.94
CD97, but not its closely related EGF-TM7 family member EMR2, is expressed on gastric, pancreatic, and esophageal carcinomas. Am J Clin Pathol (2002) 0.94
Complement activation by necrotic cells in normal plasma environment compares to that by late apoptotic cells and involves predominantly IgM. Eur J Immunol (2004) 0.94
Inhibition of coagulation, fibrinolysis, and endothelial cell activation by a p38 mitogen-activated protein kinase inhibitor during human endotoxemia. Blood (2003) 0.94
The inflammation and coagulation cross-talk in patients with systemic lupus erythematosus. Blood Coagul Fibrinolysis (2007) 0.94
Interleukin-7: a key mediator in T cell-driven autoimmunity, inflammation, and tissue destruction. Curr Pharm Des (2012) 0.93
Impaired fibrinolysis in the pathogenesis of dengue hemorrhagic fever. J Med Virol (2002) 0.93