Systemic treatment with either cyclosporin A or methotrexate does not influence the T helper 1/T helper 2 balance in psoriatic patients.

PubWeight™: 1.00‹?› | Rank: Top 15%

🔗 View Article (PMID 15163892)

Published in J Clin Immunol on July 01, 2004

Authors

Rob J Rentenaar1, Vera M R Heydendael, Frank N J van Diepen, Menno A de Rie, Ineke J M ten Berge

Author Affiliations

1: Laboratory for Experimental Immunology, Academic Medical Center, Amsterdam, The Netherlands. r.j.rentenaar@amc.uva.nl

Articles cited by this

Immunologic basis of antigen-induced airway hyperresponsiveness. Annu Rev Immunol (1999) 5.51

ELAM-1 is an adhesion molecule for skin-homing T cells. Nature (1991) 5.12

Defective T cell differentiation in the absence of Jnk1. Science (1998) 4.40

Direct demonstration of cytokine synthesis heterogeneity among human memory/effector T cells by flow cytometry. Blood (1995) 3.12

The cutaneous lymphocyte antigen is a skin lymphocyte homing receptor for the vascular lectin endothelial cell-leukocyte adhesion molecule 1. J Exp Med (1991) 3.07

Brief report: clonal proliferation of type 2 helper T cells in a man with the hypereosinophilic syndrome. N Engl J Med (1994) 2.96

A unique phenotype of skin-associated lymphocytes in humans. Preferential expression of the HECA-452 epitope by benign and malignant T cells at cutaneous sites. Am J Pathol (1990) 2.84

Cyclosporine for plaque-type psoriasis. Results of a multidose, double-blind trial. N Engl J Med (1991) 2.66

Cutaneous lymphocyte antigen is a specialized form of PSGL-1 expressed on skin-homing T cells. Nature (1997) 2.56

The majority of epidermal T cells in Psoriasis vulgaris lesions can produce type 1 cytokines, interferon-gamma, interleukin-2, and tumor necrosis factor-alpha, defining TC1 (cytotoxic T lymphocyte) and TH1 effector populations: a type 1 differentiation bias is also measured in circulating blood T cells in psoriatic patients. J Invest Dermatol (1999) 2.31

Inhibitory function of two NFAT family members in lymphoid homeostasis and Th2 development. Immunity (1998) 2.16

Methotrexate versus cyclosporine in moderate-to-severe chronic plaque psoriasis. N Engl J Med (2003) 2.12

Impaired NFATc translocation and failure of Th2 development in Itk-deficient CD4+ T cells. Immunity (1999) 2.09

Response of psoriasis to a lymphocyte-selective toxin (DAB389IL-2) suggests a primary immune, but not keratinocyte, pathogenic basis. Nat Med (1995) 2.09

The pathogenesis of psoriasis: immunological facts and speculations. Immunol Today (1999) 2.08

Inflammatory skin diseases, T cells, and immune surveillance. N Engl J Med (1999) 1.93

Interleukin-4 therapy of psoriasis induces Th2 responses and improves human autoimmune disease. Nat Med (2002) 1.86

High endothelial differentiation in human lymphoid and inflammatory tissues defined by monoclonal antibody HECA-452. Am J Pathol (1988) 1.86

Immunosuppressive properties of methotrexate: apoptosis and clonal deletion of activated peripheral T cells. J Clin Invest (1998) 1.79

The effects of cyclosporin A on T lymphocyte and dendritic cell sub-populations in psoriasis. Br J Dermatol (1987) 1.53

A systematic review of five systemic treatments for severe psoriasis. Br J Dermatol (1997) 1.46

Predominance of "memory" T cells (CD4+, CDw29+) over "naive" T cells (CD4+, CD45R+) in both normal and diseased human skin. Arch Dermatol Res (1989) 1.29

Psoriasis--an index of disability. Clin Exp Dermatol (1987) 1.28

Relative contributions of human types 1 and 2 T-helper cell-derived eosinophilotrophic cytokines to development of eosinophilia. Blood (1993) 1.17

Lymphocytes and macrophages of the epidermis and dermis in lesional psoriatic skin, but not epidermal Langerhans cells, are depleted by treatment with cyclosporin A. Arch Dermatol Res (1989) 1.15

Intermittent short courses of cyclosporin (Neoral(R)) for psoriasis unresponsive to topical therapy: a 1-year multicentre, randomized study. The PISCES Study Group. Br J Dermatol (1999) 0.96

The effects of ultraviolet B treatment on the expression of adhesion molecules by circulating T lymphocytes in psoriasis. Br J Dermatol (2003) 0.83

Cutting edge: expression of the NF of activated T cells in eosinophils: regulation by IL-4 and IL-5. J Immunol (1999) 0.81

The technicon H*1--an automated hematology analyzer for today and tomorrow. Complete blood count parameters. Am J Clin Pathol (1987) 0.80

Effects of low dose methotrexate therapy on the concentration and the glycosylation of alpha 1-acid glycoprotein in the serum of patients with rheumatoid arthritis: a longitudinal study. J Rheumatol (1994) 0.78

Short-term cyclosporin monotherapy for chronic severe plaque-type psoriasis. Eur J Dermatol (1999) 0.76

Change of treatment from cyclosporin to mycophenolate mofetil in severe psoriasis. Br J Dermatol (2000) 0.75

Differential expression of interferon gamma by mitogen-stimulated peripheral blood mononuclear cells among Kuwaiti psoriasis patients. J Dermatol (1999) 0.75

Articles by these authors

Human CD8(+) T-cell differentiation in response to viruses. Nat Rev Immunol (2003) 2.23

Methotrexate versus cyclosporine in moderate-to-severe chronic plaque psoriasis. N Engl J Med (2003) 2.12

IL-7 receptor alpha chain expression distinguishes functional subsets of virus-specific human CD8+ T cells. Blood (2005) 1.95

Emergence of a CD4+CD28- granzyme B+, cytomegalovirus-specific T cell subset after recovery of primary cytomegalovirus infection. J Immunol (2004) 1.89

Hyposplenism: comparison of different methods for determining splenic function. Am J Hematol (2012) 1.69

Rapid CD8+ T cell repertoire focusing and selection of high-affinity clones into memory following primary infection with a persistent human virus: human cytomegalovirus. J Immunol (2007) 1.56

Differential usage of cellular niches by cytomegalovirus versus EBV- and influenza virus-specific CD8+ T cells. J Immunol (2006) 1.55

Molecular profiling of cytomegalovirus-induced human CD8+ T cell differentiation. J Clin Invest (2010) 1.50

CMV-specific CD8+ T-cell function is not impaired in chronic lymphocytic leukemia. Blood (2013) 1.49

c-ANCA as a serological pitfall. Lancet (2004) 1.46

Cytomegalovirus infection reduces telomere length of the circulating T cell pool. J Immunol (2010) 1.42

Strong selection of virus-specific cytotoxic CD4+ T-cell clones during primary human cytomegalovirus infection. Blood (2006) 1.40

CD103 is a marker for alloantigen-induced regulatory CD8+ T cells. J Immunol (2006) 1.33

Clinical and immunologic aspects of cytomegalovirus infection in solid organ transplant recipients. Transplantation (2005) 1.33

Serine proteases of the human immune system in health and disease. Mol Immunol (2010) 1.30

Human virus-specific CD8+ T cells: diversity specialists. Immunol Rev (2006) 1.24

Alefacept treatment in psoriatic arthritis: reduction of the effector T cell population in peripheral blood and synovial tissue is associated with improvement of clinical signs of arthritis. Arthritis Rheum (2002) 1.22

Properties of CD4(+) T cells in human cytomegalovirus infection. Hum Immunol (2004) 1.17

Rapamycin does not induce anergy but inhibits expansion and differentiation of alloreactive human T cells. Transplantation (2006) 1.16

Effectiveness of a 5-day external stenting protocol on urological complications after renal transplantation. World J Surg (2009) 1.14

Deactivation of endothelium and reduction in angiogenesis in psoriatic skin and synovium by low dose infliximab therapy in combination with stable methotrexate therapy: a prospective single-centre study. Arthritis Res Ther (2004) 1.09

Five-year follow-up of a randomized, prospective trial of topical methyl aminolevulinate photodynamic therapy vs surgery for nodular basal cell carcinoma. Arch Dermatol (2007) 1.06

Cytomegalovirus-induced effector T cells cause endothelial cell damage. Clin Vaccine Immunol (2012) 1.02

Human cytomegalovirus infection induces a rapid and sustained change in the expression of NK cell receptors on CD8+ T cells. J Immunol (2008) 1.01

Immune responses and prediction of major infection in patients undergoing transhiatal or transthoracic esophagectomy for cancer. Ann Surg (2003) 1.01

Cross-reactivity of cytomegalovirus-specific CD8+ T cells to allo-major histocompatibility complex class I molecules. Transplantation (2004) 1.01

Immune responsiveness in renal transplant recipients: mycophenolic acid severely depresses humoral immunity in vivo. Kidney Int (2002) 0.98

The value of estimated GFR in comparison to measured GFR for the assessment of renal function in adult patients with Fabry disease. Nephrol Dial Transplant (2010) 0.94

Alloantigen-induced regulatory CD8+CD103+ T cells. Hum Immunol (2008) 0.94

The inflammation and coagulation cross-talk in patients with systemic lupus erythematosus. Blood Coagul Fibrinolysis (2007) 0.94

Digital image analysis for the evaluation of the inflammatory infiltrate in psoriasis. Arch Dermatol Res (2005) 0.91

Induction and maintenance of CD8+ T cells specific for persistent viruses. Adv Exp Med Biol (2007) 0.91

A new subset of human naive CD8+ T cells defined by low expression of IL-7R alpha. J Immunol (2007) 0.90

Expression of chemokine receptor CXCR3 by lymphocytes and plasmacytoid dendritic cells in human psoriatic lesions. Arch Dermatol Res (2009) 0.89

The burden of psoriasis is not determined by disease severity only. J Investig Dermatol Symp Proc (2004) 0.89

Detection of soluble human granzyme K in vitro and in vivo. Eur J Immunol (2005) 0.89

Skewed maturation of virus-specific CTLs? Nat Immunol (2002) 0.89

Alefacept therapy reduces the effector T-cell population in lesional psoriatic epidermis. Arch Dermatol Res (2004) 0.88

B cells in cluster or in a scattered pattern do not correlate with clinical outcome of renal allograft rejection. Transplantation (2008) 0.88

Etanercept: an overview of dermatologic adverse events. Arch Dermatol (2011) 0.87

Costs of treatment in patients with moderate to severe plaque psoriasis: economic analysis in a randomized controlled comparison of methotrexate and cyclosporine. Arch Dermatol (2004) 0.86

Rapamycin enhances the number of alloantigen-induced human CD103+CD8+ regulatory T cells in vitro. Transplantation (2007) 0.86

Phenotypic and functional characterization of circulating polyomavirus BK VP1-specific CD8+ T cells in healthy adults. J Virol (2013) 0.86

Lymphocyte subsets and T(h)1/T(h)2 immune responses in patients with adenocarcinoma of the oesophagus or oesophagogastric junction: relation to pTNM stage and clinical outcome. Cancer Immunol Immunother (2003) 0.86

Intragraft FOXP3 protein or mRNA during acute renal allograft rejection correlates with inflammation, fibrosis, and poor renal outcome. Transplantation (2009) 0.86

Interleukin-17 positive cells accumulate in renal allografts during acute rejection and are independent predictors of worse graft outcome. Transpl Int (2011) 0.85

Is a selective splinted ureterocystostomy protocol feasible in renal transplantation? An analysis of 475 renal transplantations. Transpl Int (2006) 0.84

Interstitial pneumonitis caused by everolimus: a case-cohort study in renal transplant recipients. Transpl Int (2014) 0.84

Functional re-expression of CCR7 on CMV-specific CD8+ T cells upon antigenic stimulation. Int Immunol (2005) 0.84

Monitoring the T-cell receptor repertoire at single-clone resolution. PLoS One (2006) 0.84

Intragraft tubular vimentin and CD44 expression correlate with long-term renal allograft function and interstitial fibrosis and tubular atrophy. Transplantation (2010) 0.83

Expression of urokinase plasminogen activator and its receptor during acute renal allograft rejection. Kidney Int (2003) 0.83

CXCR5+CD4+ follicular helper T cells accumulate in resting human lymph nodes and have superior B cell helper activity. Int Immunol (2013) 0.83

Ultraviolet B radiation induces a transient appearance of IL-4+ neutrophils, which support the development of Th2 responses. J Immunol (2002) 0.83

Analysis of stem-cell-like properties of human CD161++IL-18Rα+ memory CD8+ T cells. Int Immunol (2012) 0.83

Expression of the chemokine receptor CCR5 in psoriasis and results of a randomized placebo controlled trial with a CCR5 inhibitor. Arch Dermatol Res (2007) 0.82

Identification of B cell defects using age-defined reference ranges for in vivo and in vitro B cell differentiation. J Immunol (2013) 0.82

Circulating lymphocyte subsets in different clinical situations after renal transplantation. Immunology (2012) 0.82

Blood and beyond: properties of circulating and tissue-resident human virus-specific αβ CD8(+) T cells. Eur J Immunol (2014) 0.82

SerpinB9 expression in human renal tubular epithelial cells is induced by triggering of the viral dsRNA sensors TLR3, MDA5 and RIG-I. Nephrol Dial Transplant (2011) 0.82

Differentiation of human alloreactive CD4+ and CD8+ T cells in vitro. Transplantation (2004) 0.81

Renal and urinary levels of endothelial protein C receptor correlate with acute renal allograft rejection. PLoS One (2013) 0.80

In situ demonstration of CD40- and CD154-positive cells in psoriatic lesions and keratinocyte production of chemokines by CD40 ligation in vitro. J Pathol (2004) 0.80

Risk of Pneumocystis jiroveci pneumonia in patients long after renal transplantation. Nephrol Dial Transplant (2011) 0.80

Maintenance immunosuppressive therapy with everolimus preserves humoral immune responses. Kidney Int (2010) 0.80

Memory functions in prednisone-treated kidney transplant patients. Clin Transplant (2005) 0.80

Everolimus-treated renal transplant recipients have a more robust CMV-specific CD8+ T-cell response compared with cyclosporine- or mycophenolate-treated patients. Transplantation (2013) 0.79

Rise in dermal CD11c+ dendritic cells associates with early-stage development of psoriatic lesions. Arch Dermatol Res (2012) 0.79

Differentiation of human alloreactive CD8(+) T cells in vitro. Immunology (2002) 0.78

UVB irradiation of normal human skin favors the development of type-2 T-cells in vivo and in primary dermal cell cultures. Photochem Photobiol (2002) 0.77

Triple infection with HIV-1, HTLV-1 and Strongyloides stercoralis, rendering CD4+ T-cell counts a misleading entity. Antivir Ther (2013) 0.77

Analysis of risk factors in psoriatic patients with methotrexate-induced increases in transaminase levels. Arch Dermatol (2004) 0.77

Mycophenolate mofetil inhibits T-cell proliferation in kidney transplant recipients without lowering intracellular dGTP and GTP. Transpl Int (2008) 0.77

A prospective, randomized, placebo-controlled study to identify biomarkers associated with active treatment in psoriatic arthritis: effects of adalimumab treatment on lesional and nonlesional skin. Dermatology (2012) 0.76

Effects of CD25 monoclonal antibody on proliferative and effector functions of alloactivated human T cells in vitro. Eur J Immunol (2004) 0.76

Treatment of Basal Cell Carcinoma Using a One-Stop-Shop With Reflectance Confocal Microscopy: Study Design and Protocol of a Randomized Controlled Multicenter Trial. JMIR Res Protoc (2015) 0.75

The efficacy of a health-related quality-of-life intervention during 48 weeks of biologic treatment of patients with moderate to severe psoriasis: study protocol for a multicenter randomized controlled trial. Trials (2012) 0.75

Cyclosporine versus everolimus: effects on the glomerulus. Clin Transplant (2013) 0.75

Implementation of Web-based Education for Patients with Chronic Skin Disease. Acta Derm Venereol (2016) 0.75

Patient-Reported Outcome Measurement in Clinical Dermatological Practice: Relevance and Feasibility of a Web-Based Portal. Dermatology (2015) 0.75

Cyclosporin A and methotrexate are equally effective in reducing T cell numbers in psoriatic skin lesions but have no consistent effect on IFN-gamma and IL-4 expression in psoriatic skin in situ. Arch Dermatol Res (2002) 0.75

Interferon-gamma increases monocyte HLA-DR expression without effects on glucose and fat metabolism in postoperative patients. J Appl Physiol (1985) (2003) 0.75

Impact of additional vascular reconstructions on survival of kidney transplants. Int Surg (2008) 0.75

A Web-based, educational, quality-of-life intervention for patients with a chronic skin disease: feasibility and acceptance in routine dermatological practice. Acta Derm Venereol (2015) 0.75

Reduction of different inflammatory cell types of the innate immune system in psoriatic skin during etanercept treatment. Exp Dermatol (2010) 0.75