Published in J Am Chem Soc on July 07, 2010
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The dynamic character of the BCL2 promoter i-motif provides a mechanism for modulation of gene expression by compounds that bind selectively to the alternative DNA hairpin structure. J Am Chem Soc (2014) 1.06
Tertiary DNA structure in the single-stranded hTERT promoter fragment unfolds and refolds by parallel pathways via cooperative or sequential events. J Am Chem Soc (2012) 1.02
Structural and mechanical properties of individual human telomeric G-quadruplexes in molecularly crowded solutions. Nucleic Acids Res (2013) 0.96
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Direct observation of the three-state folding of a single protein molecule. Science (2005) 4.48
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Direct observation of hierarchical folding in single riboswitch aptamers. Science (2008) 3.22
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The importance of negative superhelicity in inducing the formation of G-quadruplex and i-motif structures in the c-Myc promoter: implications for drug targeting and control of gene expression. J Med Chem (2009) 2.03
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Human telomeric DNA forms parallel-stranded intramolecular G-quadruplex in K+ solution under molecular crowding condition. J Am Chem Soc (2007) 1.40
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Thermal probing of E. coli RNA polymerase off-pathway mechanisms. J Mol Biol (2008) 1.29
Duplex dissociation of telomere DNAs induced by molecular crowding. J Am Chem Soc (2004) 1.29
Single-molecule conformational analysis of G-quadruplex formation in the promoter DNA duplex of the proto-oncogene c-kit. J Am Chem Soc (2007) 1.25
Structure of a two-G-tetrad intramolecular G-quadruplex formed by a variant human telomeric sequence in K+ solution: insights into the interconversion of human telomeric G-quadruplex structures. Nucleic Acids Res (2009) 1.25
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ILPR G-quadruplexes formed in seconds demonstrate high mechanical stabilities. J Am Chem Soc (2009) 1.15
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Identification of two human nuclear proteins that recognise the cytosine-rich strand of human telomeres in vitro. Nucleic Acids Res (2000) 1.12
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The i-motif in the bcl-2 P1 promoter forms an unexpectedly stable structure with a unique 8:5:7 loop folding pattern. J Am Chem Soc (2009) 1.04
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Thermodynamics of i-tetraplex formation in the nuclease hypersensitive element of human c-myc promoter. Biochem Biophys Res Commun (2004) 1.02
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A direct and nondestructive approach to determine the folding structure of the I-motif DNA secondary structure by NMR. J Am Chem Soc (2009) 0.83
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Tunable c-MYC LNA i-motif. Chem Commun (Camb) (2009) 0.76
A single-molecule platform for investigation of interactions between G-quadruplexes and small-molecule ligands. Nat Chem (2011) 1.43
Thermal probing of E. coli RNA polymerase off-pathway mechanisms. J Mol Biol (2008) 1.29
An RNA G-quadruplex is essential for cap-independent translation initiation in human VEGF IRES. J Am Chem Soc (2010) 1.27
Investigations of bivalent antibody binding on fluid-supported phospholipid membranes: the effect of hapten density. J Am Chem Soc (2003) 1.27
ILPR G-quadruplexes formed in seconds demonstrate high mechanical stabilities. J Am Chem Soc (2009) 1.15
Intramolecular folding in three tandem guanine repeats of human telomeric DNA. Chem Commun (Camb) (2012) 1.15
An unusually stable G-quadruplex within the 5'-UTR of the MT3 matrix metalloproteinase mRNA represses translation in eukaryotic cells. Biochemistry (2009) 1.10
Replication protein A unfolds G-quadruplex structures with varying degrees of efficiency. J Phys Chem B (2012) 1.02
Tertiary DNA structure in the single-stranded hTERT promoter fragment unfolds and refolds by parallel pathways via cooperative or sequential events. J Am Chem Soc (2012) 1.02
The porphyrin TmPyP4 unfolds the extremely stable G-quadruplex in MT3-MMP mRNA and alleviates its repressive effect to enhance translation in eukaryotic cells. Nucleic Acids Res (2012) 0.97
Long-loop G-quadruplexes are misfolded population minorities with fast transition kinetics in human telomeric sequences. J Am Chem Soc (2013) 0.97
Structural and mechanical properties of individual human telomeric G-quadruplexes in molecularly crowded solutions. Nucleic Acids Res (2013) 0.96
Direct experimental evidence for quadruplex-quadruplex interaction within the human ILPR. Nucleic Acids Res (2009) 0.94
Non-B DNA structures show diverse conformations and complex transition kinetics comparable to RNA or proteins--a perspective from mechanical unfolding and refolding experiments. Chem Rec (2013) 0.92
G-quadruplex and i-motif are mutually exclusive in ILPR double-stranded DNA. Biophys J (2012) 0.91
Click chemistry assisted single-molecule fingerprinting reveals a 3D biomolecular folding funnel. J Am Chem Soc (2012) 0.91
Probing the mechanism of aqueous two-phase system formation for alpha-elastin on-chip. J Am Chem Soc (2003) 0.89
Mechanochemical properties of individual human telomeric RNA (TERRA) G-quadruplexes. Chembiochem (2013) 0.85
Single-molecule mechanochemical sensing using DNA origami nanostructures. Angew Chem Int Ed Engl (2014) 0.84
Intravesical antisense therapy for cystitis using TAT-peptide nucleic acid conjugates. Mol Pharm (2006) 0.84
Interaction of G-quadruplexes in the full-length 3' human telomeric overhang. J Am Chem Soc (2014) 0.83
Direct quantification of loop interaction and π-π stacking for G-quadruplex stability at the submolecular level. J Am Chem Soc (2014) 0.82
Pyrosequencing analysis of bacterial community and assembly in activated sludge samples from different geographic regions in China. Appl Microbiol Biotechnol (2014) 0.82
Detection of single nucleotide polymorphism using tension-dependent stochastic behavior of a single-molecule template. J Am Chem Soc (2011) 0.81
Dual binding of an antibody and a small molecule increases the stability of TERRA G-quadruplex. Angew Chem Int Ed Engl (2014) 0.80
ILPR repeats adopt diverse G-quadruplex conformations that determine insulin binding. Biopolymers (2010) 0.79
Intramolecular folding in human ILPR fragment with three C-rich repeats. PLoS One (2012) 0.79
Quantification of topological coupling between DNA superhelicity and G-quadruplex formation. J Am Chem Soc (2014) 0.79
Dissecting cooperative communications in a protein with a high-throughput single-molecule scalpel. Chemphyschem (2014) 0.77
Chemical and colloidal analyses of natural seep water collected from the exploratory studies facility inside Yucca Mountain, Nevada, USA. Environ Geochem Health (2007) 0.76
Divalent cation-aided identification of physico-chemical properties of metal ions that stabilize RNA g-quadruplexes. Biopolymers (2015) 0.76
Yoctoliter thermometry for single-molecule investigations: a generic bead-on-a-tip temperature-control module. Angew Chem Int Ed Engl (2014) 0.76
Controlled particle collision leads to direct observation of docking and fusion of lipid droplets in an optical trap. Langmuir (2014) 0.76
An Independently folding RNA G-quadruplex domain directly recruits the 40S ribosomal subunit. Biochemistry (2015) 0.76
A library screening approach identifies naturally occurring RNA sequences for a G-quadruplex binding ligand. Chem Commun (Camb) (2014) 0.76
Rationally induced RNA:DNA G-quadruplex structures elicit an anticancer effect by inhibiting endogenous eIF-4E expression. Biochemistry (2014) 0.75
Single-molecule measurements of the binding between small molecules and DNA aptamers. Anal Chem (2012) 0.75
Effects of 17β-estradiol on emissions of greenhouse gases in simulative natural water body. Environ Toxicol Chem (2015) 0.75
Correction to DNA translocation by human uracil DNA glycosylase: role of DNA phosphate charge. Biochemistry (2013) 0.75
Intermediates stabilized by tryptophan pairs exist in trpzip Beta-hairpins. Biochemistry (2014) 0.75
Incorporating layer- and local-scale heterogeneities in numerical simulation of unsaturated flow and tracer transport. J Contam Hydrol (2008) 0.75