Published in Mol Cell Biol on June 14, 2010
SUMO1-dependent modulation of SERCA2a in heart failure. Nature (2011) 1.89
Differential roles for MBD2 and MBD3 at methylated CpG islands, active promoters and binding to exon sequences. Nucleic Acids Res (2013) 1.16
Metastasis-associated protein 1/nucleosome remodeling and histone deacetylase complex in cancer. Cancer Res (2012) 1.15
Identification of hundreds of novel UPF1 target transcripts by direct determination of whole transcriptome stability. RNA Biol (2012) 1.13
MicroRNA expression signature in human abdominal aortic aneurysms. BMC Med Genomics (2012) 1.09
The proto-oncoprotein FBI-1 interacts with MBD3 to recruit the Mi-2/NuRD-HDAC complex and BCoR and to silence p21WAF/CDKN1A by DNA methylation. Nucleic Acids Res (2013) 0.94
Hypermethylated in cancer 1 (HIC1) recruits polycomb repressive complex 2 (PRC2) to a subset of its target genes through interaction with human polycomb-like (hPCL) proteins. J Biol Chem (2012) 0.93
The receptor tyrosine kinase EphA2 is a direct target gene of hypermethylated in cancer 1 (HIC1). J Biol Chem (2011) 0.93
Interferon gamma (IFN-γ) disrupts energy expenditure and metabolic homeostasis by suppressing SIRT1 transcription. Nucleic Acids Res (2011) 0.92
Loss of Hypermethylated in Cancer 1 (HIC1) in breast cancer cells contributes to stress-induced migration and invasion through β-2 adrenergic receptor (ADRB2) misregulation. J Biol Chem (2011) 0.89
Critical role of zinc finger protein 521 in the control of growth, clonogenicity and tumorigenic potential of medulloblastoma cells. Oncotarget (2013) 0.86
Role of MTA1 in cancer progression and metastasis. Cancer Metastasis Rev (2014) 0.86
DNA double-strand breaks lead to activation of hypermethylated in cancer 1 (HIC1) by SUMOylation to regulate DNA repair. J Biol Chem (2013) 0.85
Deciphering HIC1 control pathways to reveal new avenues in cancer therapeutics. Expert Opin Ther Targets (2013) 0.84
Dynamic modification of the ETS transcription factor PEA3 by sumoylation and p300-mediated acetylation. Nucleic Acids Res (2011) 0.83
HBP1-mediated transcriptional regulation of DNA methyltransferase 1 and its impact on cell senescence. Mol Cell Biol (2012) 0.81
Signification of Hypermethylated in Cancer 1 (HIC1) as Tumor Suppressor Gene in Tumor Progression. Cancer Microenviron (2012) 0.81
ATP-dependent chromatin remodeling complexes as novel targets for cancer therapy. Adv Cancer Res (2014) 0.80
Protein Kinase C-Mediated Phosphorylation of BCL11B at Serine 2 Negatively Regulates Its Interaction with NuRD Complexes during CD4+ T-Cell Activation. Mol Cell Biol (2016) 0.77
HIC1 interacts with and modulates the activity of STAT3. Cell Cycle (2013) 0.76
Signal Transduction Mechanisms of Alcoholic Fatty Liver Disease: Emerging Role of Lipin-1. Curr Mol Pharmacol (2015) 0.76
The BTB-containing protein Kctd15 is SUMOylated in vivo. PLoS One (2013) 0.76
HIC1 controls cellular- and HIV-1- gene transcription via interactions with CTIP2 and HMGA1. Sci Rep (2016) 0.75
Comparative analysis of TCDD-induced AhR-mediated gene expression in human, mouse and rat primary B cells. Toxicol Appl Pharmacol (2016) 0.75
HIC1 (hypermethylated in cancer 1) SUMOylation is dispensable for DNA repair but is essential for the apoptotic DNA damage response (DDR) to irreparable DNA double-strand breaks (DSBs). Oncotarget (2016) 0.75
HIC1 Expression Distinguishes Intestinal Carcinomas Sensitive to Chemotherapy. Transl Oncol (2016) 0.75
Hypermethylated in cancer 1(HIC1) suppresses non-small cell lung cancer progression by targeting interleukin-6/Stat3 pathway. Oncotarget (2016) 0.75
The transcriptional repressor HIC1 regulates intestinal immune homeostasis. Mucosal Immunol (2017) 0.75
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New functional activities for the p21 family of CDK inhibitors. Genes Dev (1997) 6.97
Coordinated histone modifications mediated by a CtBP co-repressor complex. Nature (2003) 6.48
The NuRD component Mbd3 is required for pluripotency of embryonic stem cells. Nat Cell Biol (2006) 5.74
The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts. EMBO J (1999) 5.44
CDK inhibitors: cell cycle regulators and beyond. Dev Cell (2008) 5.07
Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses. Cell (2005) 5.04
Nutrient availability regulates SIRT1 through a forkhead-dependent pathway. Science (2004) 4.61
Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells. Nat Cell Biol (2008) 4.30
Targeting histone deacetylase complexes via KRAB-zinc finger proteins: the PHD and bromodomains of KAP-1 form a cooperative unit that recruits a novel isoform of the Mi-2alpha subunit of NuRD. Genes Dev (2001) 4.25
Identification of a SUMO-binding motif that recognizes SUMO-modified proteins. Proc Natl Acad Sci U S A (2004) 4.19
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The human Mi-2/NuRD complex and gene regulation. Oncogene (2007) 3.76
Specification of SUMO1- and SUMO2-interacting motifs. J Biol Chem (2006) 3.59
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Modification with SUMO. A role in transcriptional regulation. EMBO Rep (2003) 3.25
MTA3 and the Mi-2/NuRD complex regulate cell fate during B lymphocyte differentiation. Cell (2004) 3.12
MBD2/NuRD and MBD3/NuRD, two distinct complexes with different biochemical and functional properties. Mol Cell Biol (2006) 3.05
Acetylation inactivates the transcriptional repressor BCL6. Nat Genet (2002) 3.00
SUMO promotes HDAC-mediated transcriptional repression. Mol Cell (2004) 2.97
Mi-2/NuRD: multiple complexes for many purposes. Biochim Biophys Acta (2004) 2.86
Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage. Nat Cell Biol (2006) 2.85
SIRT1 sumoylation regulates its deacetylase activity and cellular response to genotoxic stress. Nat Cell Biol (2007) 2.47
p53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3. Nat Med (1995) 2.47
Transcriptional regulation by C-terminal binding proteins. Int J Biochem Cell Biol (2007) 2.28
Q2ChIP, a quick and quantitative chromatin immunoprecipitation assay, unravels epigenetic dynamics of developmentally regulated genes in human carcinoma cells. Stem Cells (2007) 2.10
Retracted Metabolic regulation of SIRT1 transcription via a HIC1:CtBP corepressor complex. Proc Natl Acad Sci U S A (2007) 2.09
Metastasis tumor antigens, an emerging family of multifaceted master coregulators. J Biol Chem (2006) 2.00
Emerging roles of MTA family members in human cancers. Semin Oncol (2003) 1.99
The ups and downs of SIRT1. Trends Biochem Sci (2008) 1.97
Direct binding of CoREST1 to SUMO-2/3 contributes to gene-specific repression by the LSD1/CoREST1/HDAC complex. Mol Cell (2009) 1.81
Heterozygous disruption of Hic1 predisposes mice to a gender-dependent spectrum of malignant tumors. Nat Genet (2003) 1.77
BCL6 programs lymphoma cells for survival and differentiation through distinct biochemical mechanisms. Blood (2007) 1.72
Keeping things quiet: roles of NuRD and Sin3 co-repressor complexes during mammalian development. Int J Biochem Cell Biol (2008) 1.71
An acetylation/deacetylation-SUMOylation switch through a phylogenetically conserved psiKXEP motif in the tumor suppressor HIC1 regulates transcriptional repression activity. Mol Cell Biol (2007) 1.69
Acetylation of nuclear hormone receptor-interacting protein RIP140 regulates binding of the transcriptional corepressor CtBP. Mol Cell Biol (2001) 1.61
Retracted Requirement for chromatin-remodeling complex in novel tumor suppressor HIC1-mediated transcriptional repression and growth control. Oncogene (2008) 1.59
Progressive loss of SIRT1 with cell cycle withdrawal. Aging Cell (2006) 1.54
Analysis of the expression of cell cycle regulators in Ewing cell lines: EWS-FLI-1 modulates p57KIP2and c-Myc expression. Oncogene (2001) 1.53
B-cell lymphoma 6 and the molecular pathogenesis of diffuse large B-cell lymphoma. Curr Opin Hematol (2008) 1.47
Human cyclin D1 encodes a labile nuclear protein whose synthesis is directly induced by growth factors and suppressed by cyclic AMP. J Cell Sci (1993) 1.46
Cooperation between the Hic1 and Ptch1 tumor suppressors in medulloblastoma. Genes Dev (2008) 1.42
CtBP is an essential corepressor for BCL6 autoregulation. Mol Cell Biol (2008) 1.41
p57KIP2: "Kip"ing the cell under control. Mol Cancer Res (2009) 1.39
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MBD3, a component of the NuRD complex, facilitates chromatin alteration and deposition of epigenetic marks. Mol Cell Biol (2008) 1.36
The human candidate tumor suppressor gene HIC1 recruits CtBP through a degenerate GLDLSKK motif. Mol Cell Biol (2002) 1.34
A conserved 12-amino acid motif in Sall1 recruits the nucleosome remodeling and deacetylase corepressor complex. J Biol Chem (2006) 1.30
Mice deficient in the candidate tumor suppressor gene Hic1 exhibit developmental defects of structures affected in the Miller-Dieker syndrome. Hum Mol Genet (2000) 1.26
HIC1 interacts with a specific subunit of SWI/SNF complexes, ARID1A/BAF250A. Biochem Biophys Res Commun (2009) 1.26
The tumor suppressor gene HIC1 (hypermethylated in cancer 1) is a sequence-specific transcriptional repressor: definition of its consensus binding sequence and analysis of its DNA binding and repressive properties. J Biol Chem (2004) 1.25
Hypermethylation of HIC-1 and 17p allelic loss in medulloblastoma. Cancer Res (2002) 1.23
Sumoylation of poly(ADP-ribose) polymerase 1 inhibits its acetylation and restrains transcriptional coactivator function. FASEB J (2009) 1.15
SUMOylation attenuates the function of PGC-1alpha. J Biol Chem (2009) 1.14
HIC1 (Hypermethylated in Cancer 1) epigenetic silencing in tumors. Int J Biochem Cell Biol (2008) 1.13
SUMO engages multiple corepressors to regulate chromatin structure and transcription. Epigenetics (2009) 1.13
Characterization of the human p57KIP2 gene: alternative splicing, insertion/deletion polymorphisms in VNTR sequences in the coding region, and mutational analysis. Hum Genet (1996) 1.09
The zinc finger and C-terminal domains of MTA proteins are required for FOG-2-mediated transcriptional repression via the NuRD complex. J Mol Cell Cardiol (2007) 1.08
Identification of the p53 family-responsive element in the promoter region of the tumor suppressor gene hypermethylated in cancer 1. Oncogene (2006) 1.06
A potential tumor suppressor role for Hic1 in breast cancer through transcriptional repression of ephrin-A1. Oncogene (2010) 1.06
A phosphomimetic mutation in the Sall1 repression motif disrupts recruitment of the nucleosome remodeling and deacetylase complex and repression of Gbx2. J Biol Chem (2007) 1.03
Identification in the human candidate tumor suppressor gene HIC-1 of a new major alternative TATA-less promoter positively regulated by p53. J Biol Chem (2000) 1.02
Scavenger chemokine (CXC motif) receptor 7 (CXCR7) is a direct target gene of HIC1 (hypermethylated in cancer 1). J Biol Chem (2009) 1.01
Cellular regulation of SIRT1. Curr Pharm Des (2009) 0.93
A L225A substitution in the human tumour suppressor HIC1 abolishes its interaction with the corepressor CtBP. FEBS J (2006) 0.89
Repressed by a NuRD. Nat Cell Biol (2006) 0.88
The tumor suppressor gene hypermethylated in cancer 1 is transcriptionally regulated by E2F1. Mol Cancer Res (2009) 0.88
Implication of HIC1 (Hypermethylated In Cancer 1) in the DNA damage response. Bull Cancer (2009) 0.84
KEPE--a motif frequently superimposed on sumoylation sites in metazoan chromatin proteins and transcription factors. Bioinformatics (2008) 0.84
Retracted Metabolic regulation of SIRT1 transcription via a HIC1:CtBP corepressor complex. Proc Natl Acad Sci U S A (2007) 2.09
H19 mRNA-like noncoding RNA promotes breast cancer cell proliferation through positive control by E2F1. J Biol Chem (2005) 2.04
An acetylation/deacetylation-SUMOylation switch through a phylogenetically conserved psiKXEP motif in the tumor suppressor HIC1 regulates transcriptional repression activity. Mol Cell Biol (2007) 1.69
A topological mechanism for TRF2-enhanced strand invasion. Nat Struct Mol Biol (2007) 1.65
The human candidate tumor suppressor gene HIC1 recruits CtBP through a degenerate GLDLSKK motif. Mol Cell Biol (2002) 1.34
The transcription factor encyclopedia. Genome Biol (2012) 1.28
HIC1 interacts with a specific subunit of SWI/SNF complexes, ARID1A/BAF250A. Biochem Biophys Res Commun (2009) 1.26
The tumor suppressor gene HIC1 (hypermethylated in cancer 1) is a sequence-specific transcriptional repressor: definition of its consensus binding sequence and analysis of its DNA binding and repressive properties. J Biol Chem (2004) 1.25
Egfl7 promotes tumor escape from immunity by repressing endothelial cell activation. Cancer Res (2011) 1.20
Ubiquitin-specific protease-like 1 (USPL1) is a SUMO isopeptidase with essential, non-catalytic functions. EMBO Rep (2012) 1.15
Differential proteomic analysis of human glioblastoma and neural stem cells reveals HDGF as a novel angiogenic secreted factor. Stem Cells (2012) 1.14
HIC1 (Hypermethylated in Cancer 1) epigenetic silencing in tumors. Int J Biochem Cell Biol (2008) 1.13
TRF2 inhibits a cell-extrinsic pathway through which natural killer cells eliminate cancer cells. Nat Cell Biol (2013) 1.12
A SUMOylation-dependent pathway regulates SIRT1 transcription and lung cancer metastasis. J Natl Cancer Inst (2013) 1.04
Scavenger chemokine (CXC motif) receptor 7 (CXCR7) is a direct target gene of HIC1 (hypermethylated in cancer 1). J Biol Chem (2009) 1.01
Expression of Egfl7 correlates with low-grade invasive lesions in human breast cancer. Int J Oncol (2013) 0.95
Identification of a second G-C-rich promoter conserved in the human, murine and rat tumor suppressor genes HIC1. Oncogene (2004) 0.94
The receptor tyrosine kinase EphA2 is a direct target gene of hypermethylated in cancer 1 (HIC1). J Biol Chem (2011) 0.93
Hypermethylated in cancer 1 (HIC1) recruits polycomb repressive complex 2 (PRC2) to a subset of its target genes through interaction with human polycomb-like (hPCL) proteins. J Biol Chem (2012) 0.93
The tumor suppressor HIC1 (hypermethylated in cancer 1) is O-GlcNAc glycosylated. Eur J Biochem (2004) 0.92
Loss of Hypermethylated in Cancer 1 (HIC1) in breast cancer cells contributes to stress-induced migration and invasion through β-2 adrenergic receptor (ADRB2) misregulation. J Biol Chem (2011) 0.89
TRF2 controls telomeric nucleosome organization in a cell cycle phase-dependent manner. PLoS One (2012) 0.89
A L225A substitution in the human tumour suppressor HIC1 abolishes its interaction with the corepressor CtBP. FEBS J (2006) 0.89
The tumor suppressor gene hypermethylated in cancer 1 is transcriptionally regulated by E2F1. Mol Cancer Res (2009) 0.88
Functional characterization of human Polycomb-like 3 isoforms identifies them as components of distinct EZH2 protein complexes. Biochem J (2011) 0.86
DNA double-strand breaks lead to activation of hypermethylated in cancer 1 (HIC1) by SUMOylation to regulate DNA repair. J Biol Chem (2013) 0.85
Identification and developmental expression of the zebrafish orthologue of the tumor suppressor gene HIC1. Biochim Biophys Acta (2004) 0.85
Deciphering HIC1 control pathways to reveal new avenues in cancer therapeutics. Expert Opin Ther Targets (2013) 0.84
Implication of HIC1 (Hypermethylated In Cancer 1) in the DNA damage response. Bull Cancer (2009) 0.84
[Chromosome arm 17p13.3: could HIC1 be the one ?]. Med Sci (Paris) (2006) 0.80
Identification of p21 (CIP1/WAF1) as a direct target gene of HIC1 (Hypermethylated In Cancer 1). Biochem Biophys Res Commun (2012) 0.80
Generation of two modified mouse alleles of the Hic1 tumor suppressor gene. Genesis (2011) 0.79
Molecular dissection of the interaction between HIC1 and SIRT1. Biochem Biophys Res Commun (2012) 0.78
The Reelin receptors ApoER2 and VLDLR are direct target genes of HIC1 (Hypermethylated In Cancer 1). Biochem Biophys Res Commun (2013) 0.76
HIC1 interacts with and modulates the activity of STAT3. Cell Cycle (2013) 0.76
[Epigenetics and cancer]. Med Sci (Paris) (2005) 0.75
Arginine 469 is a pivotal residue for the Hsc70-GlcNAc-binding property. Biochem Biophys Res Commun (2010) 0.75