Published in J Cell Sci on July 01, 2010
A CHOP-regulated microRNA controls rhodopsin expression. J Cell Biol (2011) 1.22
Overview of lipid peroxidation products and hepatic protein modification in alcoholic liver disease. Chem Biol Interact (2011) 1.21
Hrd1 suppresses Nrf2-mediated cellular protection during liver cirrhosis. Genes Dev (2014) 1.16
Induction of endoplasmic reticulum stress genes, BiP and chop, in genetic and environmental models of retinal degeneration. Invest Ophthalmol Vis Sci (2012) 1.05
Endoplasmic reticulum Ca2+ depletion activates XBP1 and controls terminal differentiation in keratinocytes and epidermis. Br J Dermatol (2010) 1.01
Transcriptional profiling of chondrodysplasia growth plate cartilage reveals adaptive ER-stress networks that allow survival but disrupt hypertrophy. PLoS One (2011) 1.00
Reactive Oxygen Species, Endoplasmic Reticulum Stress and Mitochondrial Dysfunction: The Link with Cardiac Arrhythmogenesis. Front Physiol (2016) 0.93
Mechanisms of radiation toxicity in transformed and non-transformed cells. Int J Mol Sci (2013) 0.92
Chaperoning osteogenesis: new protein-folding disease paradigms. Trends Cell Biol (2010) 0.89
Nonsegmental vitiligo and autoimmune mechanism. Dermatol Res Pract (2011) 0.89
New therapeutic targets in rare genetic skeletal diseases. Expert Opin Orphan Drugs (2015) 0.87
Endoplasmic reticulum stress in amelogenesis imperfecta and phenotypic rescue using 4-phenylbutyrate. Hum Mol Genet (2013) 0.87
A mathematical model of the unfolded protein stress response reveals the decision mechanism for recovery, adaptation and apoptosis. BMC Syst Biol (2013) 0.84
Rheb Inhibits Protein Synthesis by Activating the PERK-eIF2α Signaling Cascade. Cell Rep (2015) 0.83
Thyroglobulin From Molecular and Cellular Biology to Clinical Endocrinology. Endocr Rev (2015) 0.83
Matrix disruptions, growth, and degradation of cartilage with impaired sulfation. J Biol Chem (2012) 0.82
Intracellularly-retained decorin lacking the C-terminal ear repeat causes ER stress: a cell-based etiological mechanism for congenital stromal corneal dystrophy. Am J Pathol (2013) 0.81
Novel concepts on pregnancy clocks and alarms: redundancy and synergy in human parturition. Hum Reprod Update (2016) 0.81
A novel role for Tm7sf2 gene in regulating TNFα expression. PLoS One (2013) 0.80
Uterine endoplasmic reticulum stress and its unfolded protein response may regulate caspase 3 activation in the pregnant mouse uterus. PLoS One (2013) 0.80
Endoplasmic Reticulum Stress and Disrupted Neurogenesis in the Brain Are Associated with Cognitive Impairment and Depressive-Like Behavior after Spinal Cord Injury. J Neurotrauma (2016) 0.79
A trans-acting protein effect causes severe eye malformation in the Mp mouse. PLoS Genet (2013) 0.78
Loss of VHL in mesenchymal progenitors of the limb bud alters multiple steps of endochondral bone development. Dev Biol (2014) 0.77
N-octanoyl dopamine treatment of endothelial cells induces the unfolded protein response and results in hypometabolism and tolerance to hypothermia. PLoS One (2014) 0.76
Chondrocytes Derived From Mesenchymal Stromal Cells and Induced Pluripotent Cells of Patients With Familial Osteochondritis Dissecans Exhibit an Endoplasmic Reticulum Stress Response and Defective Matrix Assembly. Stem Cells Transl Med (2016) 0.75
New insights into the unfolded protein response in stem cells. Oncotarget (2016) 0.75
Mouse models of atherosclerosis: a historical perspective and recent advances. Lipids Health Dis (2017) 0.75
Pathogenesis and treatment of spine disease in the mucopolysaccharidoses. Mol Genet Metab (2016) 0.75
Allele-specific Col1a1 silencing reduces mutant collagen in fibroblasts from Brtl mouse, a model for classical osteogenesis imperfecta. Eur J Hum Genet (2013) 0.75
β Cells that Resist Immunological Attack Develop during Progression of Autoimmune Diabetes in NOD Mice. Cell Metab (2017) 0.75
Molecular analysis of Culex quinquefasciatus larvae responses to Lysinibacillus sphaericus Bin toxin. PLoS One (2017) 0.75
Keratin 12 missense mutation induces the unfolded protein response and apoptosis in Meesmann epithelial corneal dystrophy. Hum Mol Genet (2016) 0.75
Endoplasmic Reticulum Stress and Unfolded Protein Response in Cartilage Pathophysiology; Contributing Factors to Apoptosis and Osteoarthritis. Int J Mol Sci (2017) 0.75
HIV-1 Gp120 clade B/C induces a GRP78 driven cytoprotective mechanism in astrocytoma. Oncotarget (2017) 0.75
Genomic instability in laminopathy-based premature aging. Nat Med (2005) 4.54
Sox2 is required for sensory organ development in the mammalian inner ear. Nature (2005) 3.58
Sox18 induces development of the lymphatic vasculature in mice. Nature (2008) 2.91
Prevalence and pattern of lumbar magnetic resonance imaging changes in a population study of one thousand forty-three individuals. Spine (Phila Pa 1976) (2009) 2.56
Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea. Proc Natl Acad Sci U S A (2008) 2.52
Surviving endoplasmic reticulum stress is coupled to altered chondrocyte differentiation and function. PLoS Biol (2007) 1.82
The circadian clock in murine chondrocytes regulates genes controlling key aspects of cartilage homeostasis. Arthritis Rheum (2013) 1.82
The association of lumbar intervertebral disc degeneration on magnetic resonance imaging with body mass index in overweight and obese adults: a population-based study. Arthritis Rheum (2012) 1.77
SOX9 induces and maintains neural stem cells. Nat Neurosci (2010) 1.74
Complexes of matrilin-1 and biglycan or decorin connect collagen VI microfibrils to both collagen II and aggrecan. J Biol Chem (2003) 1.72
Premature arthritis is a distinct type II collagen phenotype. Arthritis Rheum (2010) 1.66
SOX9 elevation in the prostate promotes proliferation and cooperates with PTEN loss to drive tumor formation. Cancer Res (2010) 1.64
Genome-wide association study identifies NRG1 as a susceptibility locus for Hirschsprung's disease. Proc Natl Acad Sci U S A (2009) 1.56
Identification of factors influencing strand bias in oligonucleotide-mediated recombination in Escherichia coli. Nucleic Acids Res (2003) 1.56
Oncogenicity of the developmental transcription factor Sox9. Cancer Res (2012) 1.55
Autophagic elimination of misfolded procollagen aggregates in the endoplasmic reticulum as a means of cell protection. Mol Biol Cell (2009) 1.55
Dominant collagen VI mutations are a common cause of Ullrich congenital muscular dystrophy. Hum Mol Genet (2004) 1.51
Efficient and seamless DNA recombineering using a thymidylate synthase A selection system in Escherichia coli. Nucleic Acids Res (2005) 1.51
Regeneration of intervertebral disc by mesenchymal stem cells: potentials, limitations, and future direction. Eur Spine J (2006) 1.51
Exhaustion of nucleus pulposus progenitor cells with ageing and degeneration of the intervertebral disc. Nat Commun (2012) 1.36
Increased efficiency of oligonucleotide-mediated gene repair through slowing replication fork progression. Proc Natl Acad Sci U S A (2005) 1.26
Association of the Taq I allele in vitamin D receptor with degenerative disc disease and disc bulge in a Chinese population. Spine (Phila Pa 1976) (2006) 1.24
The TRP2 allele of COL9A2 is an age-dependent risk factor for the development and severity of intervertebral disc degeneration. Spine (Phila Pa 1976) (2005) 1.24
Association of the asporin D14 allele with lumbar-disc degeneration in Asians. Am J Hum Genet (2008) 1.22
Targeted induction of endoplasmic reticulum stress induces cartilage pathology. PLoS Genet (2009) 1.21
Global comparative transcriptome analysis of cartilage formation in vivo. BMC Dev Biol (2009) 1.18
Comprehensive profiling of cartilage extracellular matrix formation and maturation using sequential extraction and label-free quantitative proteomics. Mol Cell Proteomics (2010) 1.18
Genome-wide association study identifies a susceptibility locus for biliary atresia on 10q24.2. Hum Mol Genet (2010) 1.17
SOX9 governs differentiation stage-specific gene expression in growth plate chondrocytes via direct concomitant transactivation and repression. PLoS Genet (2011) 1.16
Molecular consequences of dominant Bethlem myopathy collagen VI mutations. Ann Neurol (2007) 1.15
Genetic polymorphisms associated with intervertebral disc degeneration. Spine J (2013) 1.15
Collagen VI glycine mutations: perturbed assembly and a spectrum of clinical severity. Ann Neurol (2008) 1.14
The developmental roles of the extracellular matrix: beyond structure to regulation. Cell Tissue Res (2009) 1.12
Bulldog dwarfism in Dexter cattle is caused by mutations in ACAN. Mamm Genome (2007) 1.11
Misfolding of collagen X chains harboring Schmid metaphyseal chondrodysplasia mutations results in aberrant disulfide bond formation, intracellular retention, and activation of the unfolded protein response. J Biol Chem (2005) 1.10
ADAMTS-1-knockout mice do not exhibit abnormalities in aggrecan turnover in vitro or in vivo. Arthritis Rheum (2005) 1.09
Injury-induced sequential transformation of notochordal nucleus pulposus to chondrogenic and fibrocartilaginous phenotype in the mouse. J Pathol (2009) 1.09
S100A8 and S100A9 in experimental osteoarthritis. Arthritis Res Ther (2010) 1.08
Structure and biology of the intervertebral disk in health and disease. Orthop Clin North Am (2011) 1.08
Mutations in TRPV4 cause an inherited arthropathy of hands and feet. Nat Genet (2011) 1.07
SNP rs11190870 near LBX1 is associated with adolescent idiopathic scoliosis in southern Chinese. J Hum Genet (2012) 1.07
Copy-number variations involving the IHH locus are associated with syndactyly and craniosynostosis. Am J Hum Genet (2010) 1.06
Effect of severity of intervertebral disc injury on mesenchymal stem cell-based regeneration. Connect Tissue Res (2008) 1.06
A mutation in Ihh that causes digit abnormalities alters its signalling capacity and range. Nature (2009) 1.06
Kinked collagen VI tetramers and reduced microfibril formation as a result of Bethlem myopathy and introduced triple helical glycine mutations. J Biol Chem (2001) 1.06
Genetic susceptibility of intervertebral disc degeneration among young Finnish adults. BMC Med Genet (2011) 1.05
COL10A1 nonsense and frame-shift mutations have a gain-of-function effect on the growth plate in human and mouse metaphyseal chondrodysplasia type Schmid. Hum Mol Genet (2007) 1.02
Differential and overlapping expression pattern of SOX2 and SOX9 in inner ear development. Gene Expr Patterns (2009) 1.02
Recurrent dominant mutations affecting two adjacent residues in the motor domain of the monomeric kinesin KIF22 result in skeletal dysplasia and joint laxity. Am J Hum Genet (2011) 1.02
Mesenchymal stem cells arrest intervertebral disc degeneration through chondrocytic differentiation and stimulation of endogenous cells. Mol Ther (2009) 1.01
A microarray approach for comparative expression profiling of the discrete maturation zones of mouse growth plate cartilage. Biochim Biophys Acta (2008) 1.01
Proteomic analysis of mouse growth plate cartilage. Proteomics (2006) 1.01
Changes in the chondrocyte and extracellular matrix proteome during post-natal mouse cartilage development. Mol Cell Proteomics (2011) 1.01
Transcriptional profiling of chondrodysplasia growth plate cartilage reveals adaptive ER-stress networks that allow survival but disrupt hypertrophy. PLoS One (2011) 1.00
NOA1 is an essential GTPase required for mitochondrial protein synthesis. Mol Biol Cell (2010) 1.00
Depletion of annexin A5, annexin A6, and collagen X causes no gross changes in matrix vesicle-mediated mineralization, but lack of collagen X affects hematopoiesis and the Th1/Th2 response. J Bone Miner Res (2012) 0.99
Why mice have lost genes for COL21A1, STK17A, GPR145 and AHRI: evidence for gene deletion at evolutionary breakpoints in the rodent lineage. Trends Genet (2004) 0.99
An externally fixed femoral fracture model for mice. J Orthop Res (2003) 0.99
Lumbar disc degeneration is linked to a carbohydrate sulfotransferase 3 variant. J Clin Invest (2013) 0.98
Expression of the Trp2 allele of COL9A2 is associated with alterations in the mechanical properties of human intervertebral discs. Spine (Phila Pa 1976) (2007) 0.98
Genetic association studies in lumbar disc degeneration: a systematic review. PLoS One (2012) 0.97
Cryopreserved intervertebral disc with injected bone marrow-derived stromal cells: a feasibility study using organ culture. Spine J (2010) 0.97
Competency for nonsense-mediated reduction in collagen X mRNA is specified by the 3' UTR and corresponds to the position of mutations in Schmid metaphyseal chondrodysplasia. Am J Hum Genet (2008) 0.97
Isolated Anxa5+/Sca-1+ perivascular cells from mouse meningeal vasculature retain their perivascular phenotype in vitro and in vivo. Exp Cell Res (2007) 0.96
Proteomic characterization of mouse cartilage degradation in vitro. Arthritis Rheum (2008) 0.96
The TATA-containing core promoter of the type II collagen gene (COL2A1) is the target of interferon-gamma-mediated inhibition in human chondrocytes: requirement for Stat1 alpha, Jak1 and Jak2. Biochem J (2003) 0.96
Label-Free Quantitative Proteomics Reveals Survival Mechanisms Developed by Hypertrophic Chondrocytes under ER Stress. J Proteome Res (2015) 0.95
Collagen X chains harboring Schmid metaphyseal chondrodysplasia NC1 domain mutations are selectively retained and degraded in stably transfected cells. J Biol Chem (2002) 0.95
Employing molecular genetics of chondrodysplasias to inform the study of osteoarthritis. Arthritis Rheum (2009) 0.94
Identification of genes with allelic imbalance on 6p associated with nasopharyngeal carcinoma in southern Chinese. PLoS One (2011) 0.94
Loss of procollagen IIA from the anterior mesendoderm disrupts the development of mouse embryonic forebrain. Dev Dyn (2010) 0.94
Cartilage intermediate layer protein 2 (CILP-2) is expressed in articular and meniscal cartilage and down-regulated in experimental osteoarthritis. J Biol Chem (2011) 0.93
The molecular and cellular basis of exostosis formation in hereditary multiple exostoses. Int J Exp Pathol (2008) 0.93
Fate of growth plate hypertrophic chondrocytes: death or lineage extension? Dev Growth Differ (2015) 0.93
Homeotic arm-to-leg transformation associated with genomic rearrangements at the PITX1 locus. Am J Hum Genet (2012) 0.92
Kif5b controls the localization of myofibril components for their assembly and linkage to the myotendinous junctions. Development (2013) 0.92
WARP is a novel multimeric component of the chondrocyte pericellular matrix that interacts with perlecan. J Biol Chem (2006) 0.92
Functional replication of the tendon tissue microenvironment by a bioimprinted substrate and the support of tenocytic differentiation of mesenchymal stem cells. Biomaterials (2012) 0.92
Collagen VI microfibril formation is abolished by an {alpha}2(VI) von Willebrand factor type A domain mutation in a patient with Ullrich congenital muscular dystrophy. J Biol Chem (2010) 0.91
Proteomic analysis of cartilage proteins. Methods (2008) 0.91