Published in Peptides on June 15, 2010
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Structural insights into Bacillus thuringiensis Cry, Cyt and parasporin toxins. Toxins (Basel) (2014) 0.86
Bacillus thuringiensis subsp. israelensis and its dipteran-specific toxins. Toxins (Basel) (2014) 0.83
Dominant negative phenotype of Bacillus thuringiensis Cry1Ab, Cry11Aa and Cry4Ba mutants suggest hetero-oligomer formation among different Cry toxins. PLoS One (2011) 0.81
Transcriptional cellular responses in midgut tissue of Aedes aegypti larvae following intoxication with Cry11Aa toxin from Bacillus thuringiensis. BMC Genomics (2015) 0.81
Decreased toxicity of Bacillus thuringiensis subsp. israelensis to mosquito larvae after contact with leaf litter. Appl Environ Microbiol (2012) 0.79
Oligomerization is a key step in Cyt1Aa membrane insertion and toxicity but not necessary to synergize Cry11Aa toxicity in Aedes aegypti larvae. Environ Microbiol (2013) 0.78
Membrane binding and oligomer membrane insertion are necessary but insufficient for Bacillus thuringiensis Cyt1Aa toxicity. Peptides (2013) 0.78
The impact of strain diversity and mixed infections on the evolution of resistance to Bacillus thuringiensis. Proc Biol Sci (2013) 0.75
Improvement and efficient display of Bacillus thuringiensis toxins on M13 phages and ribosomes. AMB Express (2015) 0.75
Comparative Genomics of Bacillus thuringiensis Reveals a Path to Specialized Exploitation of Multiple Invertebrate Hosts. MBio (2017) 0.75
Mode of action of Bacillus thuringiensis Cry and Cyt toxins and their potential for insect control. Toxicon (2006) 3.27
Evaluation of synergism among Bacillus thuringiensis toxins. Appl Environ Microbiol (1992) 2.28
CytA enables CryIV endotoxins of Bacillus thuringiensis to overcome high levels of CryIV resistance in the mosquito, Culex quinquefasciatus. Proc Natl Acad Sci U S A (1997) 1.84
Crystal structure of the mosquito-larvicidal toxin Cry4Ba and its biological implications. J Mol Biol (2005) 1.75
Bacillus thuringiensis subsp. israelensis Cyt1Aa synergizes Cry11Aa toxin by functioning as a membrane-bound receptor. Proc Natl Acad Sci U S A (2005) 1.72
Synergism of mosquitocidal toxicity between CytA and CryIVD proteins using inclusions produced from cloned genes of Bacillus thuringiensis. Mol Microbiol (1994) 1.68
Signaling versus punching hole: How do Bacillus thuringiensis toxins kill insect midgut cells? Cell Mol Life Sci (2009) 1.67
How to cope with insect resistance to Bt toxins? Trends Biotechnol (2008) 1.58
A GPI-anchored alkaline phosphatase is a functional midgut receptor of Cry11Aa toxin in Aedes aegypti larvae. Biochem J (2006) 1.56
Structure of the mosquitocidal delta-endotoxin CytB from Bacillus thuringiensis sp. kyushuensis and implications for membrane pore formation. J Mol Biol (1996) 1.56
Anopheles gambiae cadherin AgCad1 binds the Cry4Ba toxin of Bacillus thuringiensis israelensis and a fragment of AgCad1 synergizes toxicity. Biochemistry (2008) 1.25
Introduction of Culex toxicity into Bacillus thuringiensis Cry4Ba by protein engineering. Appl Environ Microbiol (2003) 1.21
Aedes aegypti cadherin serves as a putative receptor of the Cry11Aa toxin from Bacillus thuringiensis subsp. israelensis. Biochem J (2009) 1.19
Bacillus thuringiensis ssp. israelensis Cyt1Aa enhances activity of Cry11Aa toxin by facilitating the formation of a pre-pore oligomeric structure. Cell Microbiol (2007) 1.17
Cytolytic toxin Cyt1A and its mechanism of membrane damage: data and hypotheses. Appl Environ Microbiol (2003) 1.15
Identification of a Bacillus thuringiensis Cry11Ba toxin-binding aminopeptidase from the mosquito, Anopheles quadrimaculatus. BMC Biochem (2006) 1.15
Cry11Aa toxin from Bacillus thuringiensis binds its receptor in Aedes aegypti mosquito larvae through loop alpha-8 of domain II. FEBS Lett (2005) 1.14
Identification and characterization of Aedes aegypti aminopeptidase N as a putative receptor of Bacillus thuringiensis Cry11A toxin. Insect Biochem Mol Biol (2009) 1.05
A 106-kDa aminopeptidase is a putative receptor for Bacillus thuringiensis Cry11Ba toxin in the mosquito Anopheles gambiae. Biochemistry (2008) 1.03
Cloning and epitope mapping of Cry11Aa-binding sites in the Cry11Aa-receptor alkaline phosphatase from Aedes aegypti. Biochemistry (2009) 0.95
Targeted mutagenesis of loop residues in the receptor-binding domain of the Bacillus thuringiensis Cry4Ba toxin affects larvicidal activity. FEMS Microbiol Lett (2005) 0.94
Toxicity and synergism in transgenic Escherichia coli expressing four genes from Bacillus thuringiensis subsp. israelensis. Environ Microbiol (2001) 0.89
Correlative effect on the toxicity of three surface-exposed loops in the receptor-binding domain of the Bacillus thuringiensis Cry4Ba toxin. FEMS Microbiol Lett (2009) 0.88
Mode of action of Bacillus thuringiensis Cry and Cyt toxins and their potential for insect control. Toxicon (2006) 3.27
Engineering modified Bt toxins to counter insect resistance. Science (2007) 2.58
RNA interference in Lepidoptera: an overview of successful and unsuccessful studies and implications for experimental design. J Insect Physiol (2010) 2.47
Bacillus thuringiensis: A story of a successful bioinsecticide. Insect Biochem Mol Biol (2011) 2.43
Structure, diversity, and evolution of protein toxins from spore-forming entomopathogenic bacteria. Annu Rev Genet (2003) 2.39
Bacillus thuringiensis insecticidal three-domain Cry toxins: mode of action, insect resistance and consequences for crop protection. FEMS Microbiol Rev (2012) 1.88
Cadherin-like receptor binding facilitates proteolytic cleavage of helix alpha-1 in domain I and oligomer pre-pore formation of Bacillus thuringiensis Cry1Ab toxin. FEBS Lett (2002) 1.86
Bacillus thuringiensis subsp. israelensis Cyt1Aa synergizes Cry11Aa toxin by functioning as a membrane-bound receptor. Proc Natl Acad Sci U S A (2005) 1.72
How to cope with insect resistance to Bt toxins? Trends Biotechnol (2008) 1.58
A GPI-anchored alkaline phosphatase is a functional midgut receptor of Cry11Aa toxin in Aedes aegypti larvae. Biochem J (2006) 1.56
Heliothis virescens and Manduca sexta lipid rafts are involved in Cry1A toxin binding to the midgut epithelium and subsequent pore formation. J Biol Chem (2002) 1.38
Single amino acid mutations in the cadherin receptor from Heliothis virescens affect its toxin binding ability to Cry1A toxins. J Biol Chem (2004) 1.35
Domain II loop 3 of Bacillus thuringiensis Cry1Ab toxin is involved in a "ping pong" binding mechanism with Manduca sexta aminopeptidase-N and cadherin receptors. J Biol Chem (2009) 1.32
Diversity of Bacillus thuringiensis strains from Latin America with insecticidal activity against different mosquito species. Appl Environ Microbiol (2003) 1.30
Role of alkaline phosphatase from Manduca sexta in the mechanism of action of Bacillus thuringiensis Cry1Ab toxin. J Biol Chem (2010) 1.29
Bacillus thuringiensis Cry1Ab mutants affecting oligomer formation are non-toxic to Manduca sexta larvae. J Biol Chem (2007) 1.27
Specific epitopes of domains II and III of Bacillus thuringiensis Cry1Ab toxin involved in the sequential interaction with cadherin and aminopeptidase-N receptors in Manduca sexta. J Biol Chem (2006) 1.24
Structural changes of the Cry1Ac oligomeric pre-pore from bacillus thuringiensis induced by N-acetylgalactosamine facilitates toxin membrane insertion. Biochemistry (2006) 1.23
Molecular basis for Bacillus thuringiensis Cry1Ab toxin specificity: two structural determinants in the Manduca sexta Bt-R1 receptor interact with loops alpha-8 and 2 in domain II of Cy1Ab toxin. Biochemistry (2003) 1.22
Aedes aegypti cadherin serves as a putative receptor of the Cry11Aa toxin from Bacillus thuringiensis subsp. israelensis. Biochem J (2009) 1.19
Efficacy of genetically modified Bt toxins against insects with different genetic mechanisms of resistance. Nat Biotechnol (2011) 1.19
Bacillus thuringiensis ssp. israelensis Cyt1Aa enhances activity of Cry11Aa toxin by facilitating the formation of a pre-pore oligomeric structure. Cell Microbiol (2007) 1.17
The mitogen-activated protein kinase p38 is involved in insect defense against Cry toxins from Bacillus thuringiensis. Insect Biochem Mol Biol (2009) 1.16
Cry11Aa toxin from Bacillus thuringiensis binds its receptor in Aedes aegypti mosquito larvae through loop alpha-8 of domain II. FEBS Lett (2005) 1.14
Evolution of Bacillus thuringiensis Cry toxins insecticidal activity. Microb Biotechnol (2012) 1.14
Enhancement of insecticidal activity of Bacillus thuringiensis Cry1A toxins by fragments of a toxin-binding cadherin correlates with oligomer formation. Peptides (2008) 1.13
Hydropathic complementarity determines interaction of epitope (869)HITDTNNK(876) in Manduca sexta Bt-R(1) receptor with loop 2 of domain II of Bacillus thuringiensis Cry1A toxins. J Biol Chem (2002) 1.10
Mode of action of mosquitocidal Bacillus thuringiensis toxins. Toxicon (2006) 1.09
Pore formation by Cry toxins. Adv Exp Med Biol (2010) 1.00
Tryptophan spectroscopy studies and black lipid bilayer analysis indicate that the oligomeric structure of Cry1Ab toxin from Bacillus thuringiensis is the membrane-insertion intermediate. Biochemistry (2004) 1.00
Cadherin, alkaline phosphatase, and aminopeptidase N as receptors of Cry11Ba toxin from Bacillus thuringiensis subsp. jegathesan in Aedes aegypti. Appl Environ Microbiol (2010) 0.98
An ADAM metalloprotease is a Cry3Aa Bacillus thuringiensis toxin receptor. Biochem Biophys Res Commun (2007) 0.97
Characterization of the mechanism of action of the genetically modified Cry1AbMod toxin that is active against Cry1Ab-resistant insects. Biochim Biophys Acta (2009) 0.95
A Bacillus thuringiensis S-layer protein involved in toxicity against Epilachna varivestis (Coleoptera: Coccinellidae). Appl Environ Microbiol (2006) 0.95
Cloning and epitope mapping of Cry11Aa-binding sites in the Cry11Aa-receptor alkaline phosphatase from Aedes aegypti. Biochemistry (2009) 0.95
Unfolding events in the water-soluble monomeric Cry1Ab toxin during transition to oligomeric pre-pore and membrane-inserted pore channel. J Biol Chem (2004) 0.95
Cyt toxins produced by Bacillus thuringiensis: a protein fold conserved in several pathogenic microorganisms. Peptides (2012) 0.95
Role of MAPK p38 in the cellular responses to pore-forming toxins. Peptides (2010) 0.93
Differential role of Manduca sexta aminopeptidase-N and alkaline phosphatase in the mode of action of Cry1Aa, Cry1Ab, and Cry1Ac toxins from Bacillus thuringiensis. Appl Environ Microbiol (2013) 0.93
Functional display of Bacillus thuringiensis Cry1Ac toxin on T7 phage. J Invertebr Pathol (2006) 0.93
Genetic variability of Spodoptera frugiperda Smith (Lepidoptera: Noctuidae) populations from Latin America is associated with variations in susceptibility to Bacillus thuringiensis cry toxins. Appl Environ Microbiol (2006) 0.92
A system for the directed evolution of the insecticidal protein from Bacillus thuringiensis. Mol Biotechnol (2007) 0.92
Dominant negative mutants of Bacillus thuringiensis Cry1Ab toxin function as anti-toxins: demonstration of the role of oligomerization in toxicity. PLoS One (2009) 0.91
An alpha-amylase is a novel receptor for Bacillus thuringiensis ssp. israelensis Cry4Ba and Cry11Aa toxins in the malaria vector mosquito Anopheles albimanus (Diptera: Culicidae). Environ Microbiol (2009) 0.90
Multiple receptors as targets of Cry toxins in mosquitoes. J Agric Food Chem (2011) 0.90
Modified Bacillus thuringiensis toxins and a hybrid B. thuringiensis strain counter greenhouse-selected resistance in Trichoplusia ni. Appl Environ Microbiol (2009) 0.89
Midgut GPI-anchored proteins with alkaline phosphatase activity from the cotton boll weevil (Anthonomus grandis) are putative receptors for the Cry1B protein of Bacillus thuringiensis. Insect Biochem Mol Biol (2010) 0.89
Comparative proteomic analysis of Aedes aegypti larval midgut after intoxication with Cry11Aa toxin from Bacillus thuringiensis. PLoS One (2012) 0.89
Pore formation activity of Cry1Ab toxin from Bacillus thuringiensis in an improved membrane vesicle preparation from Manduca sexta midgut cell microvilli. Biochim Biophys Acta (2002) 0.88
Single concentration tests show synergism among Bacillus thuringiensis subsp. israelensis toxins against the malaria vector mosquito Anopheles albimanus. J Invertebr Pathol (2010) 0.88
Cadherin binding is not a limiting step for Bacillus thuringiensis subsp. israelensis Cry4Ba toxicity to Aedes aegypti larvae. Biochem J (2012) 0.87
Defense and death responses to pore forming toxins. Biotechnol Genet Eng Rev (2010) 0.85
The amino- and carboxyl-terminal fragments of the Bacillus thuringensis Cyt1Aa toxin have differential roles in toxin oligomerization and pore formation. Biochemistry (2010) 0.84
Efficacy of genetically modified Bt toxins alone and in combinations against pink bollworm resistant to Cry1Ac and Cry2Ab. PLoS One (2013) 0.84
Oligomerization of Cry11Aa from Bacillus thuringiensis has an important role in toxicity against Aedes aegypti. Appl Environ Microbiol (2009) 0.84
Aedes aegypti alkaline phosphatase ALP1 is a functional receptor of Bacillus thuringiensis Cry4Ba and Cry11Aa toxins. Insect Biochem Mol Biol (2012) 0.83
Identification of distinct K+ channels in mouse spermatogenic cells and sperm. Zygote (2002) 0.83
Role of tryptophan residues in toxicity of Cry1Ab toxin from Bacillus thuringiensis. Appl Environ Microbiol (2006) 0.83
Assessment of cry1 gene contents of Bacillus thuringiensis strains by use of DNA microarrays. Appl Environ Microbiol (2005) 0.83
Structural and functional analysis of the pre-pore and membrane-inserted pore of Cry1Ab toxin. J Invertebr Pathol (2006) 0.82
Role of UPR pathway in defense response of Aedes aegypti against Cry11Aa toxin from Bacillus thuringiensis. Int J Mol Sci (2013) 0.81