Published in Biochemistry on December 29, 2010
Contribution of S-layer proteins to the mosquitocidal activity of Lysinibacillus sphaericus. PLoS One (2014) 0.89
Structural insights into Bacillus thuringiensis Cry, Cyt and parasporin toxins. Toxins (Basel) (2014) 0.86
Bacillus thuringiensis subsp. israelensis and its dipteran-specific toxins. Toxins (Basel) (2014) 0.83
Oligomerization is a key step in Cyt1Aa membrane insertion and toxicity but not necessary to synergize Cry11Aa toxicity in Aedes aegypti larvae. Environ Microbiol (2013) 0.78
The elimination of DNA from the Cry toxin-DNA complex is a necessary step in the mode of action of the Cry8 toxin. PLoS One (2013) 0.76
Bacillus thuringiensis Cyt2Aa2 toxin disrupts cell membranes by forming large protein aggregates. Biosci Rep (2016) 0.75
Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa. Anal Biochem (1987) 59.79
Bacillus thuringiensis and its pesticidal crystal proteins. Microbiol Mol Biol Rev (1998) 13.47
Bacillus thuringiensis var israelensis crystal delta-endotoxin: effects on insect and mammalian cells in vitro and in vivo. J Cell Sci (1983) 4.85
Construction of cloning vectors for Bacillus thuringiensis. Gene (1991) 4.58
Mechanism of action of Bacillus thuringiensis var israelensis insecticidal delta-endotoxin. FEBS Lett (1983) 2.72
Structure, diversity, and evolution of protein toxins from spore-forming entomopathogenic bacteria. Annu Rev Genet (2003) 2.39
Oligomerization triggers binding of a Bacillus thuringiensis Cry1Ab pore-forming toxin to aminopeptidase N receptor leading to insertion into membrane microdomains. Biochim Biophys Acta (2004) 2.37
Comparative toxicity of Bacillus thuringiensis var. israelensis crystal proteins in vivo and in vitro. J Gen Microbiol (1988) 2.30
Evaluation of synergism among Bacillus thuringiensis toxins. Appl Environ Microbiol (1992) 2.28
A 20-kilodalton protein preserves cell viability and promotes CytA crystal formation during sporulation in Bacillus thuringiensis. J Bacteriol (1993) 1.95
Bacillus thuringiensis subsp. israelensis Cyt1Aa synergizes Cry11Aa toxin by functioning as a membrane-bound receptor. Proc Natl Acad Sci U S A (2005) 1.72
Synergism of mosquitocidal toxicity between CytA and CryIVD proteins using inclusions produced from cloned genes of Bacillus thuringiensis. Mol Microbiol (1994) 1.68
Structure of the mosquitocidal delta-endotoxin CytB from Bacillus thuringiensis sp. kyushuensis and implications for membrane pore formation. J Mol Biol (1996) 1.56
A cytolytic delta-endotoxin from Bacillus thuringiensis var. israelensis forms cation-selective channels in planar lipid bilayers. FEBS Lett (1989) 1.39
Domain II loop 3 of Bacillus thuringiensis Cry1Ab toxin is involved in a "ping pong" binding mechanism with Manduca sexta aminopeptidase-N and cadherin receptors. J Biol Chem (2009) 1.32
Bacillus thuringiensis ssp. israelensis Cyt1Aa enhances activity of Cry11Aa toxin by facilitating the formation of a pre-pore oligomeric structure. Cell Microbiol (2007) 1.17
Cytolytic toxin Cyt1A and its mechanism of membrane damage: data and hypotheses. Appl Environ Microbiol (2003) 1.15
Binding and aggregation of the 25-kilodalton toxin of Bacillus thuringiensis subsp. israelensis to cell membranes and alteration by monoclonal antibodies and amino acid modifiers. Appl Environ Microbiol (1989) 1.14
Role of toxin activation on binding and pore formation activity of the Bacillus thuringiensis Cry3 toxins in membranes of Leptinotarsa decemlineata (Say). Biochim Biophys Acta (2004) 1.12
A broad-spectrum cytolytic toxin from Bacillus thuringiensis var. kyushuensis. Proc Biol Sci (1992) 1.02
Membrane pore architecture of a cytolytic toxin from Bacillus thuringiensis. Biochem J (2000) 1.01
Bacillus thuringiensis cytolytic toxin associates specifically with its synthetic helices A and C in the membrane bound state. Implications for the assembly of oligomeric transmembrane pores. Biochemistry (1997) 1.00
Biochemical characterization of Bacillus thuringiensis cytolytic toxins in association with a phospholipid bilayer. Biochem J (1999) 0.99
Cyt1Aa protein of bacillus thuringiensis is toxic to the cottonwood leaf beetle, chrysomela scripta, and suppresses high levels of resistance to Cry3Aa Appl Environ Microbiol (1998) 0.97
Characterization of the mechanism of action of the genetically modified Cry1AbMod toxin that is active against Cry1Ab-resistant insects. Biochim Biophys Acta (2009) 0.95
A detergent-like mechanism of action of the cytolytic toxin Cyt1A from Bacillus thuringiensis var. israelensis. Biochemistry (2005) 0.93
High-resolution crystal structure of activated Cyt2Ba monomer from Bacillus thuringiensis subsp. israelensis. J Mol Biol (2008) 0.92
Investigation of the pore-forming mechanism of a cytolytic delta-endotoxin from Bacillus thuringiensis. Biochem J (2003) 0.90
Amino acid substitutions in alphaA and alphaC of Cyt2Aa2 alter hemolytic activity and mosquito-larvicidal specificity. J Biotechnol (2007) 0.89
Functional domains of a pore-forming cardiotoxic protein, volvatoxin A2. J Biol Chem (2003) 0.85
Isolation and partial characterization of three lethal and hemolytic toxins from the sea anemone Actinia cari. Toxicon (1982) 0.78
Mode of action of Bacillus thuringiensis Cry and Cyt toxins and their potential for insect control. Toxicon (2006) 3.27
Engineering modified Bt toxins to counter insect resistance. Science (2007) 2.58
RNA interference in Lepidoptera: an overview of successful and unsuccessful studies and implications for experimental design. J Insect Physiol (2010) 2.47
Bacillus thuringiensis: A story of a successful bioinsecticide. Insect Biochem Mol Biol (2011) 2.43
Structure, diversity, and evolution of protein toxins from spore-forming entomopathogenic bacteria. Annu Rev Genet (2003) 2.39
Sindbis virus induces transport processes and alters expression of innate immunity pathway genes in the midgut of the disease vector, Aedes aegypti. Insect Biochem Mol Biol (2005) 1.98
Bacillus thuringiensis insecticidal three-domain Cry toxins: mode of action, insect resistance and consequences for crop protection. FEMS Microbiol Rev (2012) 1.88
Cadherin-like receptor binding facilitates proteolytic cleavage of helix alpha-1 in domain I and oligomer pre-pore formation of Bacillus thuringiensis Cry1Ab toxin. FEBS Lett (2002) 1.86
Bacillus thuringiensis subsp. israelensis Cyt1Aa synergizes Cry11Aa toxin by functioning as a membrane-bound receptor. Proc Natl Acad Sci U S A (2005) 1.72
How to cope with insect resistance to Bt toxins? Trends Biotechnol (2008) 1.58
Blood meal induces global changes in midgut gene expression in the disease vector, Aedes aegypti. Insect Biochem Mol Biol (2003) 1.57
A GPI-anchored alkaline phosphatase is a functional midgut receptor of Cry11Aa toxin in Aedes aegypti larvae. Biochem J (2006) 1.56
Deletion of the ecdysis-triggering hormone gene leads to lethal ecdysis deficiency. Development (2002) 1.42
Heliothis virescens and Manduca sexta lipid rafts are involved in Cry1A toxin binding to the midgut epithelium and subsequent pore formation. J Biol Chem (2002) 1.38
P-type Na+/K+-ATPase and V-type H+-ATPase expression patterns in the osmoregulatory organs of larval and adult mosquito Aedes aegypti. J Exp Biol (2006) 1.36
Single amino acid mutations in the cadherin receptor from Heliothis virescens affect its toxin binding ability to Cry1A toxins. J Biol Chem (2004) 1.35
Domain II loop 3 of Bacillus thuringiensis Cry1Ab toxin is involved in a "ping pong" binding mechanism with Manduca sexta aminopeptidase-N and cadherin receptors. J Biol Chem (2009) 1.32
Diversity of Bacillus thuringiensis strains from Latin America with insecticidal activity against different mosquito species. Appl Environ Microbiol (2003) 1.30
Role of alkaline phosphatase from Manduca sexta in the mechanism of action of Bacillus thuringiensis Cry1Ab toxin. J Biol Chem (2010) 1.29
Bacillus thuringiensis Cry1Ab mutants affecting oligomer formation are non-toxic to Manduca sexta larvae. J Biol Chem (2007) 1.27
Specific epitopes of domains II and III of Bacillus thuringiensis Cry1Ab toxin involved in the sequential interaction with cadherin and aminopeptidase-N receptors in Manduca sexta. J Biol Chem (2006) 1.24
Structural changes of the Cry1Ac oligomeric pre-pore from bacillus thuringiensis induced by N-acetylgalactosamine facilitates toxin membrane insertion. Biochemistry (2006) 1.23
Molecular basis for Bacillus thuringiensis Cry1Ab toxin specificity: two structural determinants in the Manduca sexta Bt-R1 receptor interact with loops alpha-8 and 2 in domain II of Cy1Ab toxin. Biochemistry (2003) 1.22
Mimetics of caloric restriction include agonists of lipid-activated nuclear receptors. J Biol Chem (2004) 1.21
Aedes aegypti cadherin serves as a putative receptor of the Cry11Aa toxin from Bacillus thuringiensis subsp. israelensis. Biochem J (2009) 1.19
Inactivation of the polycomb group protein Ring1B unveils an antiproliferative role in hematopoietic cell expansion and cooperation with tumorigenesis associated with Ink4a deletion. Mol Cell Biol (2007) 1.19
Efficacy of genetically modified Bt toxins against insects with different genetic mechanisms of resistance. Nat Biotechnol (2011) 1.19
Characterization of a HKT-type transporter in rice as a general alkali cation transporter. Plant J (2002) 1.18
Bacillus thuringiensis ssp. israelensis Cyt1Aa enhances activity of Cry11Aa toxin by facilitating the formation of a pre-pore oligomeric structure. Cell Microbiol (2007) 1.17
The mitogen-activated protein kinase p38 is involved in insect defense against Cry toxins from Bacillus thuringiensis. Insect Biochem Mol Biol (2009) 1.16
Cry11Aa toxin from Bacillus thuringiensis binds its receptor in Aedes aegypti mosquito larvae through loop alpha-8 of domain II. FEBS Lett (2005) 1.14
Evolution of Bacillus thuringiensis Cry toxins insecticidal activity. Microb Biotechnol (2012) 1.14
Enhancement of insecticidal activity of Bacillus thuringiensis Cry1A toxins by fragments of a toxin-binding cadherin correlates with oligomer formation. Peptides (2008) 1.13
Hydropathic complementarity determines interaction of epitope (869)HITDTNNK(876) in Manduca sexta Bt-R(1) receptor with loop 2 of domain II of Bacillus thuringiensis Cry1A toxins. J Biol Chem (2002) 1.10
Mode of action of mosquitocidal Bacillus thuringiensis toxins. Toxicon (2006) 1.09
Identification and characterization of Aedes aegypti aminopeptidase N as a putative receptor of Bacillus thuringiensis Cry11A toxin. Insect Biochem Mol Biol (2009) 1.05
Gene expression changes induced in mouse liver by di(2-ethylhexyl) phthalate. Toxicol Appl Pharmacol (2002) 1.01
Pore formation by Cry toxins. Adv Exp Med Biol (2010) 1.00
Tryptophan spectroscopy studies and black lipid bilayer analysis indicate that the oligomeric structure of Cry1Ab toxin from Bacillus thuringiensis is the membrane-insertion intermediate. Biochemistry (2004) 1.00
NHE8 mediates amiloride-sensitive Na+/H+ exchange across mosquito Malpighian tubules and catalyzes Na+ and K+ transport in reconstituted proteoliposomes. Am J Physiol Renal Physiol (2007) 1.00
Molecular cloning and function of ecdysis-triggering hormones in the silkworm Bombyx mori. J Exp Biol (2002) 0.98
Cadherin, alkaline phosphatase, and aminopeptidase N as receptors of Cry11Ba toxin from Bacillus thuringiensis subsp. jegathesan in Aedes aegypti. Appl Environ Microbiol (2010) 0.98
An ADAM metalloprotease is a Cry3Aa Bacillus thuringiensis toxin receptor. Biochem Biophys Res Commun (2007) 0.97
Binding of Bacillus thuringiensis subsp. israelensis Cry4Ba to Cyt1Aa has an important role in synergism. Peptides (2010) 0.96
Characterization of the mechanism of action of the genetically modified Cry1AbMod toxin that is active against Cry1Ab-resistant insects. Biochim Biophys Acta (2009) 0.95
A Bacillus thuringiensis S-layer protein involved in toxicity against Epilachna varivestis (Coleoptera: Coccinellidae). Appl Environ Microbiol (2006) 0.95
Cloning and epitope mapping of Cry11Aa-binding sites in the Cry11Aa-receptor alkaline phosphatase from Aedes aegypti. Biochemistry (2009) 0.95
Unfolding events in the water-soluble monomeric Cry1Ab toxin during transition to oligomeric pre-pore and membrane-inserted pore channel. J Biol Chem (2004) 0.95
Cyt toxins produced by Bacillus thuringiensis: a protein fold conserved in several pathogenic microorganisms. Peptides (2012) 0.95
Epoxygenated fatty acids and soluble epoxide hydrolase inhibition: novel mediators of pain reduction. J Agric Food Chem (2010) 0.94
Maintenance of undifferentiated state and self-renewal of embryonic neural stem cells by Polycomb protein Ring1B. Stem Cells (2009) 0.94