Roderick J Flower

Author PubWeight™ 55.48‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis. Nature 2009 3.27
2 Aberrant inflammation and resistance to glucocorticoids in annexin 1-/- mouse. FASEB J 2002 2.13
3 Resolvin D1 limits polymorphonuclear leukocyte recruitment to inflammatory loci: receptor-dependent actions. Arterioscler Thromb Vasc Biol 2012 1.67
4 Annexin 1 and its bioactive peptide inhibit neutrophil-endothelium interactions under flow: indication of distinct receptor involvement. Blood 2005 1.62
5 Leukocyte antiadhesive actions of annexin 1: ALXR- and FPR-related anti-inflammatory mechanisms. Blood 2003 1.60
6 Cutting edge: Humanized nano-proresolving medicines mimic inflammation-resolution and enhance wound healing. J Immunol 2011 1.52
7 Spatial and temporal profiles for anti-inflammatory gene expression in leukocytes during a resolving model of peritonitis. J Immunol 2006 1.52
8 Ligand-specific conformational change of the G-protein-coupled receptor ALX/FPR2 determines proresolving functional responses. Proc Natl Acad Sci U S A 2013 1.49
9 Annexin 1-deficient neutrophils exhibit enhanced transmigration in vivo and increased responsiveness in vitro. J Leukoc Biol 2005 1.43
10 Modulation of inflammation and response to dexamethasone by Annexin 1 in antigen-induced arthritis. Arthritis Rheum 2004 1.39
11 NCX-1015, a nitric-oxide derivative of prednisolone, enhances regulatory T cells in the lamina propria and protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis in mice. Proc Natl Acad Sci U S A 2002 1.36
12 Dexamethasone induces rapid serine-phosphorylation and membrane translocation of annexin 1 in a human folliculostellate cell line via a novel nongenomic mechanism involving the glucocorticoid receptor, protein kinase C, phosphatidylinositol 3-kinase, and mitogen-activated protein kinase. Endocrinology 2003 1.28
13 Critical protective role for annexin 1 gene expression in the endotoxemic murine microcirculation. Am J Pathol 2005 1.27
14 Activation of the annexin 1 counter-regulatory circuit affords protection in the mouse brain microcirculation. FASEB J 2007 1.22
15 Annexin A1 regulates intestinal mucosal injury, inflammation, and repair. J Immunol 2008 1.18
16 Activation of melanocortin type 3 receptor as a molecular mechanism for adrenocorticotropic hormone efficacy in gouty arthritis. Arthritis Rheum 2002 1.15
17 Redundancy of a functional melanocortin 1 receptor in the anti-inflammatory actions of melanocortin peptides: studies in the recessive yellow (e/e) mouse suggest an important role for melanocortin 3 receptor. J Immunol 2003 1.13
18 Ligand-specific glucocorticoid receptor activation in human platelets. Blood 2005 1.12
19 Annexin-1 modulates T-cell activation and differentiation. Blood 2006 1.10
20 Annexin 1 cleavage in activated neutrophils: a pivotal role for proteinase 3. J Biol Chem 2007 1.10
21 An overview of the effects of annexin 1 on cells involved in the inflammatory process. Mem Inst Oswaldo Cruz 2005 1.08
22 Annexin-1 modulates repair of gastric mucosal injury. Am J Physiol Gastrointest Liver Physiol 2008 1.03
23 Evidence for an anti-inflammatory loop centered on polymorphonuclear leukocyte formyl peptide receptor 2/lipoxin A4 receptor and operative in the inflamed microvasculature. J Immunol 2011 1.00
24 Impaired T cell activation and increased Th2 lineage commitment in Annexin-1-deficient T cells. Eur J Immunol 2007 0.99
25 Functional and ultrastructural analysis of annexin A1 and its receptor in extravasating neutrophils during acute inflammation. Am J Pathol 2008 0.99
26 A vasculo-protective circuit centered on lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 operative in murine microcirculation. Blood 2013 0.98
27 Potent antiarthritic properties of a glucocorticoid derivative, NCX-1015, in an experimental model of arthritis. Proc Natl Acad Sci U S A 2002 0.97
28 Annexin 1, glucocorticoids, and the neuroendocrine-immune interface. Ann N Y Acad Sci 2006 0.97
29 Impaired phagocytic mechanism in annexin 1 null macrophages. Br J Pharmacol 2006 0.96
30 Annexin 1 and the regulation of endocrine function. Trends Endocrinol Metab 2004 0.96
31 A novel effect for annexin 1-derived peptide ac2-26: reduction of allergic inflammation in the rat. J Pharmacol Exp Ther 2005 0.95
32 Antiallergic cromones inhibit neutrophil recruitment onto vascular endothelium via annexin-A1 mobilization. Arterioscler Thromb Vasc Biol 2010 0.94
33 Attenuation of plasma annexin A1 in human obesity. FASEB J 2012 0.91
34 Treatment of inflammatory diseases by selective eicosanoid inhibition: a double-edged sword? Trends Pharmacol Sci 2007 0.90
35 Annexin A1 interaction with the FPR2/ALX receptor: identification of distinct domains and downstream associated signaling. J Biol Chem 2012 0.89
36 Stimulus-specific defect in the phagocytic pathways of annexin 1 null macrophages. Br J Pharmacol 2004 0.89
37 Annexin-1-deficient dendritic cells acquire a mature phenotype during differentiation. FASEB J 2008 0.88
38 Gene deletion reveals roles for annexin A1 in the regulation of lipolysis and IL-6 release in epididymal adipose tissue. Am J Physiol Endocrinol Metab 2006 0.87
39 Role of endogenous annexin-A1 in the regulation of thymocyte positive and negative selection. Cell Cycle 2010 0.87
40 Targeting the melanocortin receptor system for anti-stroke therapy. Trends Pharmacol Sci 2010 0.83
41 Paracetamol-induced hypothermia is independent of cannabinoids and transient receptor potential vanilloid-1 and is not mediated by AM404. Drug Metab Dispos 2011 0.83
42 Glucocorticoid receptor nitration leads to enhanced anti-inflammatory effects of novel steroid ligands. J Immunol 2003 0.82
43 Antiflammin-2 activates the human formyl-peptide receptor like 1. ScientificWorldJournal 2006 0.81
44 Endogenous annexin A1 counter-regulates bleomycin-induced lung fibrosis. BMC Immunol 2011 0.81
45 Investigation into the involvement of phospholipases A2 and map kinases in modulation of AA release and cell growth in A549 cells. Adv Exp Med Biol 2002 0.78
46 Anti-allergic drugs and the Annexin-A1 system. Pharmacol Rep 2010 0.76
47 The acute and chronic phases of chronic relapsing experimental autoimmune encephalomyelitis (CR EAE) are ameliorated by the peroxynitrite decomposition catalyst, 5,10,15,20-tetrakis(4-sulfonatophenyl)porphyrinatoiron (III) chloride, (FeTPPS). Eur J Pharmacol 2008 0.76
48 A comparative evaluation of the response to peroxynitrite by a brain endothelial cell line and control of the effects by drug targeting. Cell Mol Neurobiol 2009 0.75