Published in Ir J Med Sci on June 19, 2010
Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis. Nat Genet (1994) 4.40
Neutrophil elastase in respiratory epithelial lining fluid of individuals with cystic fibrosis induces interleukin-8 gene expression in a human bronchial epithelial cell line. J Clin Invest (1992) 2.62
A preliminary study of aerosolized recombinant human deoxyribonuclease I in the treatment of cystic fibrosis. N Engl J Med (1992) 2.57
Protease-antiprotease imbalance in the lungs of children with cystic fibrosis. Am J Respir Crit Care Med (1994) 2.26
Systemic deficiency of glutathione in cystic fibrosis. J Appl Physiol (1985) (1993) 1.88
Oxidation of either methionine 351 or methionine 358 in alpha 1-antitrypsin causes loss of anti-neutrophil elastase activity. J Biol Chem (2000) 1.82
Prepared for internship? Ir Med J (2009) 1.74
A hyoscine-resistant contraction of isolated chicken oesophagus in response to stimulation of parasymphathetic nerves. Br J Pharmacol (1969) 1.70
Some actions of histamine and 5-hydroxytryptamine on isolated chicken oesophagus. Br J Pharmacol Chemother (1968) 1.62
The SCID mouse: an experimental model for endometriosis. Hum Reprod (1999) 1.54
Expression of HCLCA1 in cystic fibrosis lungs is associated with mucus overproduction. Eur Respir J (2004) 1.54
Interleukin-8 up-regulation by neutrophil elastase is mediated by MyD88/IRAK/TRAF-6 in human bronchial epithelium. J Biol Chem (2001) 1.41
Effects of repeated days of intensified training on muscle glycogen and swimming performance. Med Sci Sports Exerc (1988) 1.41
Mood disturbance following increased training in swimmers. Med Sci Sports Exerc (1988) 1.35
Modification of nasal epithelial potential differences of individuals with cystic fibrosis consequent to local administration of a normal CFTR cDNA adenovirus gene transfer vector. Hum Gene Ther (1995) 1.34
Cathepsin B, L, and S cleave and inactivate secretory leucoprotease inhibitor. J Biol Chem (2001) 1.30
Association of IL-10 polymorphism with severity of illness in community acquired pneumonia. Thorax (2003) 1.28
Contraction of chicken rectum to nerve stimulation after blockade of sympathetic and parasympathetic transmission. Q J Exp Physiol Cogn Med Sci (1971) 1.25
Role of IL-18 in CD4+ T lymphocyte activation in sarcoidosis. J Immunol (2000) 1.17
Adrenoceptors of the chick rectum. Br J Pharmacol (1970) 1.12
Ambient pCO2 modulates intracellular pH, intracellular oxidant generation, and interleukin-8 secretion in human neutrophils. J Leukoc Biol (2002) 1.11
Influence of selected carbohydrate drinks on cycling performance and glycogen use. Med Sci Sports Exerc (1987) 1.10
Quantitative assessment of the epithelial and inflammatory cell populations in large airways of normals and individuals with cystic fibrosis. Am J Respir Crit Care Med (1996) 1.07
Increased elastase release by CF neutrophils is mediated by tumor necrosis factor-alpha and interleukin-8. Am J Physiol Lung Cell Mol Physiol (2000) 1.03
External versus internal approach to the removal of metallic intraocular foreign bodies. Retina (2000) 1.03
Recombinant secretory leukoprotease inhibitor augments glutathione levels in lung epithelial lining fluid. J Appl Physiol (1985) (1993) 1.02
Two case reports of pneumomediastinum. Ir J Med Sci (2007) 1.02
Prediction of heart rate and oxygen uptake during incremental and maximal exercise in healthy adults. Chest (1994) 1.02
The action of physostigmine and the distribution of cholinesterases in the chicken oesophagus. Br J Pharmacol Chemother (1968) 1.01
IL-6 release and airway administration of human CFR cDNA adenovirus vector. Nat Med (1995) 0.98
Alpha1-antitrypsin deficiency: biological answers to clinical questions. Am J Med Sci (2001) 0.97
Serum beta-endorphin levels during a graded exercise test to exhaustion. Med Sci Sports Exerc (1987) 0.97
Vitamin D receptor agonists inhibit pro-inflammatory cytokine production from the respiratory epithelium in cystic fibrosis. J Cyst Fibros (2011) 0.96
The role of secretory leucoprotease inhibitor in the resolution of inflammatory responses. Biochem Soc Trans (2007) 0.95
Alpha-1 antitrypsin deficiency: a conformational disease associated with lung and liver manifestations. J Inherit Metab Dis (2008) 0.95
Effects of carbohydrate ingestion on gastric emptying and exercise performance. Med Sci Sports Exerc (1988) 0.93
Improvements in exercise performance: effects of carbohydrate feedings and diet. J Appl Physiol (1985) (1987) 0.93
Glutathione aerosol suppresses lung epithelial surface inflammatory cell-derived oxidants in cystic fibrosis. J Appl Physiol (1985) (1999) 0.93
Effects of stimulation of the cervical vagus and descending oesophageal nerves on the alimentary tract of the domestic fowl. Zentralbl Veterinarmed A (1967) 0.92
Tissue-specific and androgen-repressible regulation of the rat dehydroepiandrosterone sulfotransferase gene promoter. J Biol Chem (1998) 0.92
Physiological responses to successive days of intense training in competitive swimmers. Med Sci Sports Exerc (1988) 0.92
Ulcerative terminal ileitis after BCG therapy for bladder carcinoma. Histopathology (2002) 0.92
Effect of 4 wk of deep water run training on running performance. Med Sci Sports Exerc (1997) 0.91
Pancreatic disease in AIDS--a review. J Clin Gastroenterol (1993) 0.91
Recombinant DNA-produced alpha 1-antitrypsin administered by aerosol augments lower respiratory tract antineutrophil elastase defenses in individuals with alpha 1-antitrypsin deficiency. J Clin Invest (1989) 0.91
A nerve-blocking action of MJ-1999. Br J Pharmacol (1969) 0.91
Determinants of success during triathlon competition. Res Q Exerc Sport (1989) 0.90
Anti-apoptotic effects of Z alpha1-antitrypsin in human bronchial epithelial cells. Eur Respir J (2009) 0.89
Intravenous recombinant secretory leukoprotease inhibitor augments antineutrophil elastase defense. J Appl Physiol (1985) (1992) 0.89
Effect of reduced training on muscular strength and endurance in competitive swimmers. Med Sci Sports Exerc (1987) 0.89
High concentrations of pepsin in bronchoalveolar lavage fluid from children with cystic fibrosis are associated with high interleukin-8 concentrations. Thorax (2010) 0.88
Molecular characterization of a glycosylphosphatidylinositol-linked ADP-ribosyltransferase from lymphocytes. Blood (1996) 0.87
Opioid receptor modulation of postexercise hypotension. Med Sci Sports Exerc (1992) 0.86
Normal values and ranges for ventilation and breathing pattern at maximal exercise. Chest (1991) 0.86
Development of predictive models for airflow obstruction in alpha-1-antitrypsin deficiency. Am J Epidemiol (2009) 0.86
Alpha-1-antitrypsin aerosolised augmentation abrogates neutrophil elastase-induced expression of cathepsin B and matrix metalloprotease 2 in vivo and in vitro. Thorax (2008) 0.86
Heritability of lung function in severe alpha-1 antitrypsin deficiency. Hum Hered (2008) 0.86
Effects of endurance training on selected parameters of immune function in elderly women. Gerontology (2000) 0.85
The Immediate Management of the Patient with Rupture: Open Versus Endovascular repair (IMPROVE) aneurysm trial--ISRCTN 48334791 IMPROVE trialists. Acta Chir Belg (2010) 0.84
Team Objective Structured Bedside Assessment (TOSBA): a novel and feasible way of providing formative teaching and assessment. Med Teach (2007) 0.83
Effects of intensified training and detraining on testicular function. Clin J Sport Med (1999) 0.83
Attitudes and perceptions of fitness professionals regarding obesity. J Community Health (2000) 0.83
Skin cauterisation marks on patients in Saudi Arabia. Lancet (1983) 0.82
The effect of training on the norepinephrine response at rest and during exercise in 5 degrees and 20 degrees C environments. J Sports Med Phys Fitness (1990) 0.82
A case of dapsone induced methaemoglobinaemia. Ir J Med Sci (2008) 0.82
Pleural fluid analysis: standstill or a work in progress? Pulm Med (2012) 0.81
Anti-proteinase 3 antibody activation of neutrophils can be inhibited by alpha1-antitrypsin. Am J Respir Cell Mol Biol (2001) 0.81
Persistant right lower lobe consolidation. Chest (2000) 0.81
Carbohydrate balance in competitive runners during successive days of intense training. J Appl Physiol (1985) (1988) 0.81
Influence of sodium bicarbonate on sprint performance: relationship to dosage. Med Sci Sports Exerc (1988) 0.81
An outreach programme for patients with an exacerbation of chronic obstructive pulmonary disease. Ir Med J (2003) 0.80
Evaluation of the need for endoscopy to identify low-risk patients presenting with an acute upper gastrointestinal bleed suitable for early discharge. Postgrad Med J (2007) 0.80
Altered intracellular pH regulation in neutrophils from patients with cystic fibrosis. Am J Physiol Lung Cell Mol Physiol (2000) 0.80
Tracheal deviation as a sign in ill patients: beware ipsilateral pathology. J Accid Emerg Med (1998) 0.80
Measurement of body composition changes with weight loss in postmenopausal women: comparison of methods. J Nutr Health Aging (2007) 0.80
Resistance exercise effects on plasma cortisol, testosterone and creatine kinase activity in anabolic-androgenic steroid users. Int J Sports Med (1990) 0.80
Demodex-associated bacterial proteins induce neutrophil activation. Br J Dermatol (2012) 0.79
Iron status and resting immune function in female collegiate swimmers. Int J Sport Nutr Exerc Metab (2000) 0.79
The effects of chondroitin sulfate supplementation on indices of muscle damage induced by eccentric arm exercise. J Sports Med Phys Fitness (2005) 0.79
Serum beta-endorphin and affective responses to graded exercise in young and elderly men. J Gerontol (1987) 0.79
Effects of reduced training on submaximal and maximal running responses. Int J Sports Med (1989) 0.78
Gene therapy for the respiratory manifestations of cystic fibrosis. Am J Respir Crit Care Med (1995) 0.78
Gastrointestinal and hepatic effects of Amanita phalloides ingestion. J Clin Gastroenterol (1992) 0.78
Influence of carbohydrate ingestion on counterregulatory hormones during prolonged exercise. Int J Sports Med (1990) 0.78
Actions of morphine and sympathomimetic amines on isolated chick oesophagus. East Afr Med J (1976) 0.78
A rare case of multiple bronchial artery aneurysms associated with a double aortic arch. Singapore Med J (2015) 0.78
Effects of hormone replacement therapy on selected indices of immune function in postmenopausal women. Gynecol Obstet Invest (2000) 0.78
Electrophysiologic actions of pirmenol in dogs with recent myocardial infarction. Am Heart J (1986) 0.78
Radiological abnormalities associated with Aspergillus colonization in a cystic fibrosis population. Eur J Radiol (2011) 0.78
Identification of patients with low-risk pulmonary embolism suitable for outpatient treatment using the pulmonary embolism severity index (PESI). Ir J Med Sci (2012) 0.78
Air quality impacts mortality in acute medical admissions. QJM (2013) 0.78
Resistive exercise blunts LPS-stimulated TNF-alpha and Il-1 beta. Int J Sports Med (2007) 0.77
Fibronectin does not enhance epidermal growth factor-mediated acceleration of corneal epithelial wound closure. Arch Ophthalmol (1989) 0.77
Serum haptoglobin and ferritin during a competitive running and swimming season. Int J Sports Med (1997) 0.77
The efficacy of furazolidone against experimental infections with Trypanosoma evansi in camels and mice in Sudan: comparisons with quinapyramine and suramin. Rev Elev Med Vet Pays Trop (1986) 0.77
Influence of acute submaximal exercise on T-lymphocyte suppressor cell function in healthy young men. Eur J Appl Physiol (2000) 0.77
Gastrointestinal obstruction due to Mycobacterium avium intracellulare associated with the acquired immunodeficiency syndrome. Am J Gastroenterol (1992) 0.76