Published in Free Radic Biol Med on June 04, 2010
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter. Proc Natl Acad Sci U S A (2010) 1.63
Carbon nanoparticles induce ceramide- and lipid raft-dependent signalling in lung epithelial cells: a target for a preventive strategy against environmentally-induced lung inflammation. Part Fibre Toxicol (2012) 0.96
The oxidative potential of differently charged silver and gold nanoparticles on three human lung epithelial cell types. J Nanobiotechnology (2015) 0.84
Feasibility of biomarker studies for engineered nanoparticles: what can be learned from air pollution research. J Occup Environ Med (2011) 0.83
Repeated PM2.5 exposure inhibits BEAS-2B cell P53 expression through ROS-Akt-DNMT3B pathway-mediated promoter hypermethylation. Oncotarget (2016) 0.81
Hypoxia induces connexin 43 dysregulation by modulating matrix metalloproteinases via MAPK signaling. Mol Cell Biochem (2013) 0.81
A work group report on ultrafine particles (American Academy of Allergy, Asthma & Immunology): Why ambient ultrafine and engineered nanoparticles should receive special attention for possible adverse health outcomes in human subjects. J Allergy Clin Immunol (2016) 0.81
Intracellular signal modulation by nanomaterials. Adv Exp Med Biol (2014) 0.78
Activation of Proinflammatory Responses in Cells of the Airway Mucosa by Particulate Matter: Oxidant- and Non-Oxidant-Mediated Triggering Mechanisms. Biomolecules (2015) 0.78
Cellular Response to Titanium Dioxide Nanoparticles in Intestinal Epithelial Caco-2 Cells is Dependent on Endocytosis-Associated Structures and Mediated by EGFR. Nanomaterials (Basel) (2017) 0.75
Oxidative stress and calcium signaling in the adverse effects of environmental particles (PM10). Free Radic Biol Med (2003) 2.28
Yeast Ataxin-7 links histone deubiquitination with gene gating and mRNA export. Nat Cell Biol (2008) 2.27
Lightening up the UV response by identification of the arylhydrocarbon receptor as a cytoplasmatic target for ultraviolet B radiation. Proc Natl Acad Sci U S A (2007) 2.08
Polybrominated diphenyl ethers induce developmental neurotoxicity in a human in vitro model: evidence for endocrine disruption. Environ Health Perspect (2010) 1.75
Inhaled particles and lung cancer. Part A: Mechanisms. Int J Cancer (2004) 1.73
Structural basis for assembly and activation of the heterotetrameric SAGA histone H2B deubiquitinase module. Cell (2010) 1.66
Endocytosis, oxidative stress and IL-8 expression in human lung epithelial cells upon treatment with fine and ultrafine TiO2: role of the specific surface area and of surface methylation of the particles. Toxicol Appl Pharmacol (2007) 1.61
Metal-rich ambient particles (particulate matter 2.5) cause airway inflammation in healthy subjects. Am J Respir Crit Care Med (2004) 1.59
Variation of the N-acetyltransferase 2 gene in a Romanian and a Kyrgyz population. Cancer Epidemiol Biomarkers Prev (2006) 1.38
Development of in vitro systems for nanotoxicology: methodological considerations. Crit Rev Toxicol (2009) 1.33
Neutrophils and respiratory tract DNA damage and mutagenesis: a review. Mutagenesis (2006) 1.30
The surface area rather than the surface coating determines the acute inflammatory response after instillation of fine and ultrafine TiO2 in the rat. Int J Hyg Environ Health (2002) 1.27
Activation of the inflammasome by amorphous silica and TiO2 nanoparticles in murine dendritic cells. Nanotoxicology (2010) 1.27
Hydroxyl radical generation by electron paramagnetic resonance as a new method to monitor ambient particulate matter composition. J Environ Monit (2003) 1.22
Science and government. An international framework to promote access to data. Science (2004) 1.19
Soluble metals as well as the insoluble particle fraction are involved in cellular DNA damage induced by particulate matter. Mol Cell Biochem (2002) 1.19
Transition metals in personal samples of PM2.5 and oxidative stress in human volunteers. Cancer Epidemiol Biomarkers Prev (2005) 1.19
Human neurospheres as three-dimensional cellular systems for developmental neurotoxicity testing. Environ Health Perspect (2009) 1.18
Analysis of the transcriptional regulation and molecular function of the aryl hydrocarbon receptor repressor in human cell lines. Drug Metab Dispos (2007) 1.16
Growth factors, cytokines and their receptors as downstream targets of arylhydrocarbon receptor (AhR) signaling pathways. Biochem Pharmacol (2008) 1.16
Effect of prolonged exposure to diesel engine exhaust on proinflammatory markers in different regions of the rat brain. Part Fibre Toxicol (2010) 1.15
Age-associated analysis of oxidative stress parameters in human plasma and erythrocytes. Free Radic Res (2006) 1.14
Head and neck squamous-cell cancer and its association with polymorphic enzymes of xenobiotic metabolism and repair. J Toxicol Environ Health A (2008) 1.14
The quercetin paradox. Toxicol Appl Pharmacol (2007) 1.14
Oxidant generation by particulate matter: from biologically effective dose to a promising, novel metric. Occup Environ Med (2007) 1.14
Inhaled particles and lung cancer, part B: paradigms and risk assessment. Int J Cancer (2004) 1.13
The compatible solute ectoine protects against nanoparticle-induced neutrophilic lung inflammation. Am J Respir Crit Care Med (2009) 1.08
Ultrafine carbon particles induce apoptosis and proliferation in rat lung epithelial cells via specific signaling pathways both using EGF-R. Am J Physiol Lung Cell Mol Physiol (2006) 1.05
Polychlorinated biphenyls disturb differentiation of normal human neural progenitor cells: clue for involvement of thyroid hormone receptors. Environ Health Perspect (2005) 1.04
Nuclear protein tyrosine phosphatase Shp-2 is one important negative regulator of nuclear export of telomerase reverse transcriptase. J Biol Chem (2008) 1.00
Expression profiling and genetic alterations of the selenoproteins GI-GPx and SePP in colorectal carcinogenesis. Nutr Cancer (2004) 1.00
Zinc oxide nanoparticles induce necrosis and apoptosis in macrophages in a p47phox- and Nrf2-independent manner. PLoS One (2013) 0.99
Recovery of neutrophil apoptosis by ectoine: a new strategy against lung inflammation. Eur Respir J (2012) 0.98
Contrasting macrophage activation by fine and ultrafine titanium dioxide particles is associated with different uptake mechanisms. Part Fibre Toxicol (2011) 0.98
The arylhydrocarbon receptor repressor (AhRR): structure, expression, and function. Biol Chem (2006) 0.98
The AhR-Nrf2 pathway in keratinocytes: on the road to chemoprevention? J Invest Dermatol (2012) 0.98
Inflammatory time course after quartz instillation: role of tumor necrosis factor-alpha and particle surface. Am J Respir Cell Mol Biol (2004) 0.97
Neutrophil-derived ROS contribute to oxidative DNA damage induction by quartz particles. Free Radic Biol Med (2010) 0.97
Associations of urban air particulate composition with inflammatory and cytotoxic responses in RAW 246.7 cell line. Inhal Toxicol (2009) 0.97
Peroxynitrite signaling: receptor tyrosine kinases and activation of stress-responsive pathways. Free Radic Biol Med (2002) 0.97
Carbon nanoparticles induce ceramide- and lipid raft-dependent signalling in lung epithelial cells: a target for a preventive strategy against environmentally-induced lung inflammation. Part Fibre Toxicol (2012) 0.96
Distinctive toxicity of TiO2 rutile/anatase mixed phase nanoparticles on Caco-2 cells. Chem Res Toxicol (2012) 0.96
Possible genotoxic mechanisms of nanoparticles: criteria for improved test strategies. Nanotoxicology (2010) 0.95
Creatine supplementation normalizes mutagenesis of mitochondrial DNA as well as functional consequences. J Invest Dermatol (2005) 0.94
Hydroxyl-radical-dependent DNA damage by ambient particulate matter from contrasting sampling locations. Environ Res (2005) 0.93
Infrared A radiation influences the skin fibroblast transcriptome: mechanisms and consequences. J Invest Dermatol (2010) 0.93
Neutrophils augment LPS-mediated pro-inflammatory signaling in human lung epithelial cells. Biochim Biophys Acta (2012) 0.93
Role of mitochondria in photoaging of human skin: the defective powerhouse model. J Investig Dermatol Symp Proc (2009) 0.93
Role of alcohol and genetic polymorphisms of CYP2E1 and ALDH2 in breast cancer development. Pharmacogenetics (2003) 0.93
A complex DNA-repeat structure within the Selenoprotein P promoter contains a functionally relevant polymorphism and is genetically unstable under conditions of mismatch repair deficiency. Eur J Hum Genet (2002) 0.93
Cutaneous effects of infrared radiation: from clinical observations to molecular response mechanisms. Photodermatol Photoimmunol Photomed (2003) 0.92
Aryl hydrocarbon receptor repressor (AhRR) function revisited: repression of CYP1 activity in human skin fibroblasts is not related to AhRR expression. J Invest Dermatol (2012) 0.92
Comparative evaluation of the effects of short-term inhalation exposure to diesel engine exhaust on rat lung and brain. Arch Toxicol (2010) 0.92
c-Src-mediated activation of Erk1/2 is a reaction of epithelial cells to carbon nanoparticle treatment and may be a target for a molecular preventive strategy. Biol Chem (2010) 0.92
Irradiation of GAPDH: a model for environmentally induced protein damage. Biol Chem (2007) 0.91
The crucial role of particle surface reactivity in respirable quartz-induced reactive oxygen/nitrogen species formation and APE/Ref-1 induction in rat lung. Respir Res (2005) 0.91
Tissue distribution and function of the Aryl hydrocarbon receptor repressor (AhRR) in C57BL/6 and Aryl hydrocarbon receptor deficient mice. Arch Toxicol (2006) 0.91
Distinct spectrum of mutations induced by crocidolite asbestos: clue for 8-hydroxydeoxyguanosine-dependent mutagenesis in vivo. Cancer Res (2002) 0.91
DNA damage in lung epithelial cells isolated from rats exposed to quartz: role of surface reactivity and neutrophilic inflammation. Carcinogenesis (2002) 0.90
Adaptation of topoisomerase I paralogs to nuclear and mitochondrial DNA. Nucleic Acids Res (2009) 0.90
Carbon nanoparticle-induced lung epithelial cell proliferation is mediated by receptor-dependent Akt activation. Am J Physiol Lung Cell Mol Physiol (2007) 0.90
A prevalent POLG CAG microsatellite length allele in humans and African great apes. Mamm Genome (2004) 0.89
Oxidant generation and toxicity of size-fractionated ambient particles in human lung epithelial cells. Environ Sci Technol (2010) 0.89
The proteasome is an integral part of solar ultraviolet a radiation-induced gene expression. J Biol Chem (2009) 0.87
ERK-dependent and -independent pathways trigger human neural progenitor cell migration. Toxicol Appl Pharmacol (2007) 0.87
Increase of inflammatory markers after indoor renovation activities: the LISA birth cohort study. Pediatr Allergy Immunol (2009) 0.87
Mutational uncoupling of the role of Sus1 in nuclear pore complex targeting of an mRNA export complex and histone H2B deubiquitination. J Biol Chem (2009) 0.87
Assessment of successful experiments and limitations of phytotechnologies: contaminant uptake, detoxification and sequestration, and consequences for food safety. Environ Sci Pollut Res Int (2009) 0.87
Surface-dependent quartz uptake by macrophages: potential role in pulmonary inflammation and lung clearance. Inhal Toxicol (2007) 0.86
Influence of simulated gastrointestinal conditions on particle-induced cytotoxicity and interleukin-8 regulation in differentiated and undifferentiated Caco-2 cells. Nanotoxicology (2012) 0.86
Formation of PAH-DNA adducts after in vivo and vitro exposure of rats and lung cells to different commercial carbon blacks. Toxicol Appl Pharmacol (2005) 0.85
beta1-integrin mediates asbestos-induced phosphorylation of AKT and ERK1/2 in a rat pleural mesothelial cell line. Oncogene (2003) 0.85
Evaluation of apoptosis induced by nanoparticles and fine particles in RAW 264.7 macrophages: facts and artefacts. Toxicol In Vitro (2011) 0.84
Particle induced toxicity in relation to transition metal and polycyclic aromatic hydrocarbon contents. Environ Sci Technol (2009) 0.84
Environmental arsenic exposure from a coal-burning power plant as a potential risk factor for nonmelanoma skin carcinoma: results from a case-control study in the district of Prievidza, Slovakia. Am J Epidemiol (2002) 0.84
Xenobiotic metabolism capacities of human skin in comparison with a 3D-epidermis model and keratinocyte-based cell culture as in vitro alternatives for chemical testing: phase II enzymes. Exp Dermatol (2012) 0.84
Mechanisms of neutrophil-induced DNA damage in respiratory tract epithelial cells. Mol Cell Biochem (2002) 0.84
Actin plays a crucial role in the phagocytosis and biological response to respirable quartz particles in macrophages. Arch Toxicol (2007) 0.84
The forkhead transcription factor FOXO4 sensitizes cancer cells to doxorubicin-mediated cytotoxicity. Carcinogenesis (2008) 0.83
Investigation of the cytotoxic and proinflammatory effects of cement dusts in rat alveolar macrophages. Chem Res Toxicol (2009) 0.83
Differential glucocorticoid effects on repair mechanisms and NF-kappaB activity in the intestinal epithelium. Regul Pept (2002) 0.83
Evaluation of cytotoxic effects and oxidative stress with hydroxyapatite dispersions of different physicochemical properties in rat NR8383 cells and primary macrophages. Toxicol In Vitro (2009) 0.83
Regulation of dioxin receptor function by different beta-carboline alkaloids. Arch Toxicol (2010) 0.83
Nitrite enhances neutrophil-induced DNA strand breakage in pulmonary epithelial cells by inhibition of myeloperoxidase. Carcinogenesis (2005) 0.82
Surface iron inhibits quartz-induced cytotoxic and inflammatory responses in alveolar macrophages. Chem Res Toxicol (2010) 0.82
Signal transduction pathways relevant for neoplastic effects of fibrous and non-fibrous particles. Mutat Res (2004) 0.82
Curcumin protects against cytotoxic and inflammatory effects of quartz particles but causes oxidative DNA damage in a rat lung epithelial cell line. Toxicol Appl Pharmacol (2007) 0.81
A comparative study of different in vitro lung cell culture systems to assess the most beneficial tool for screening the potential adverse effects of carbon nanotubes. Toxicol Sci (2013) 0.81
Role of the aryl hydrocarbon receptor in tobacco smoke extract-induced matrix metalloproteinase-1 expression. Exp Dermatol (2013) 0.81