Published in Toxicol Appl Pharmacol on June 01, 2005
The potential risks of nanomaterials: a review carried out for ECETOC. Part Fibre Toxicol (2006) 3.56
Carbon black nanoparticle instillation induces sustained inflammation and genotoxicity in mouse lung and liver. Part Fibre Toxicol (2012) 1.04
Pulmonary exposure to carbon black by inhalation or instillation in pregnant mice: effects on liver DNA strand breaks in dams and offspring. Nanotoxicology (2011) 1.02
Carbon nanoparticles induce ceramide- and lipid raft-dependent signalling in lung epithelial cells: a target for a preventive strategy against environmentally-induced lung inflammation. Part Fibre Toxicol (2012) 0.96
Translational toxicology in setting occupational exposure limits for dusts and hazard classification - a critical evaluation of a recent approach to translate dust overload findings from rats to humans. Part Fibre Toxicol (2015) 0.90
Health effects research and regulation of diesel exhaust: an historical overview focused on lung cancer risk. Inhal Toxicol (2012) 0.89
Biological effects of carbon black nanoparticles are changed by surface coating with polycyclic aromatic hydrocarbons. Part Fibre Toxicol (2017) 0.75
Safe handling of nanotechnology. Nature (2006) 7.25
Translocation of inhaled ultrafine manganese oxide particles to the central nervous system. Environ Health Perspect (2006) 3.16
Oxidative stress and calcium signaling in the adverse effects of environmental particles (PM10). Free Radic Biol Med (2003) 2.28
Ultrafine particle deposition in humans during rest and exercise. Inhal Toxicol (2003) 2.06
Non-alcoholic steatohepatitis: a non-invasive diagnosis by analysis of exhaled breath. J Hepatol (2012) 1.87
Size dependence of the translocation of inhaled iridium and carbon nanoparticle aggregates from the lung of rats to the blood and secondary target organs. Inhal Toxicol (2009) 1.78
Ultrafine particles in the urban air: to the respiratory tract--and beyond? Environ Health Perspect (2002) 1.76
Inhaled particles and lung cancer. Part A: Mechanisms. Int J Cancer (2004) 1.73
The influence of protein adsorption on nanoparticle association with cultured endothelial cells. Biomaterials (2008) 1.68
Efficient elimination of inhaled nanoparticles from the alveolar region: evidence for interstitial uptake and subsequent reentrainment onto airways epithelium. Environ Health Perspect (2007) 1.65
Meeting report: hazard assessment for nanoparticles--report from an interdisciplinary workshop. Environ Health Perspect (2007) 1.64
Does Nanoparticle Activity Depend upon Size and Crystal Phase? Nanotoxicology (2008) 1.62
Endocytosis, oxidative stress and IL-8 expression in human lung epithelial cells upon treatment with fine and ultrafine TiO2: role of the specific surface area and of surface methylation of the particles. Toxicol Appl Pharmacol (2007) 1.61
Concept of assessing nanoparticle hazards considering nanoparticle dosemetric and chemical/biological response metrics. J Toxicol Environ Health A (2010) 1.61
Metal-rich ambient particles (particulate matter 2.5) cause airway inflammation in healthy subjects. Am J Respir Crit Care Med (2004) 1.59
Interlaboratory evaluation of rodent pulmonary responses to engineered nanomaterials: the NIEHS Nano GO Consortium. Environ Health Perspect (2013) 1.52
Correlating physico-chemical with toxicological properties of nanoparticles: the present and the future. ACS Nano (2010) 1.49
Pulmonary function, diffusing capacity, and inflammation in healthy and asthmatic subjects exposed to ultrafine particles. Inhal Toxicol (2004) 1.45
Inhalation of ultrafine particles alters blood leukocyte expression of adhesion molecules in humans. Environ Health Perspect (2006) 1.44
Ultrafine particle deposition in subjects with asthma. Environ Health Perspect (2004) 1.40
Development of in vitro systems for nanotoxicology: methodological considerations. Crit Rev Toxicol (2009) 1.33
Neutrophils and respiratory tract DNA damage and mutagenesis: a review. Mutagenesis (2006) 1.30
Effects of subchronically inhaled carbon black in three species. I. Retention kinetics, lung inflammation, and histopathology. Toxicol Sci (2005) 1.30
The rat ear vein model for investigating in vivo thrombogenicity of ultrafine particles (UFP). Toxicol Sci (2005) 1.29
The surface area rather than the surface coating determines the acute inflammatory response after instillation of fine and ultrafine TiO2 in the rat. Int J Hyg Environ Health (2002) 1.27
Activation of the inflammasome by amorphous silica and TiO2 nanoparticles in murine dendritic cells. Nanotoxicology (2010) 1.27
Effects of exposure to ultrafine carbon particles in healthy subjects and subjects with asthma. Res Rep Health Eff Inst (2004) 1.25
Equivalent titanium dioxide nanoparticle deposition by intratracheal instillation and whole body inhalation: the effect of dose rate on acute respiratory tract inflammation. Part Fibre Toxicol (2014) 1.24
Hydroxyl radical generation by electron paramagnetic resonance as a new method to monitor ambient particulate matter composition. J Environ Monit (2003) 1.22
Translocation and effects of ultrafine particles outside of the lung. Clin Occup Environ Med (2006) 1.20
Soluble metals as well as the insoluble particle fraction are involved in cellular DNA damage induced by particulate matter. Mol Cell Biochem (2002) 1.19
Transition metals in personal samples of PM2.5 and oxidative stress in human volunteers. Cancer Epidemiol Biomarkers Prev (2005) 1.19
Changes in deceleration capacity of heart rate and heart rate variability induced by ambient air pollution in individuals with coronary artery disease. Part Fibre Toxicol (2010) 1.16
Effect of prolonged exposure to diesel engine exhaust on proinflammatory markers in different regions of the rat brain. Part Fibre Toxicol (2010) 1.15
The quercetin paradox. Toxicol Appl Pharmacol (2007) 1.14
Oxidant generation by particulate matter: from biologically effective dose to a promising, novel metric. Occup Environ Med (2007) 1.14
Inhaled particles and lung cancer, part B: paradigms and risk assessment. Int J Cancer (2004) 1.13
Surface modification of quartz inhibits toxicity, particle uptake, and oxidative DNA damage in human lung epithelial cells. Chem Res Toxicol (2002) 1.12
Continued controversy on chrysotile biopersistence. Int J Occup Environ Health (2011) 1.12
Concepts of nanoparticle dose metric and response metric. Environ Health Perspect (2007) 1.12
The origin, fate, and health effects of combustion by-products: a research framework. Environ Health Perspect (2002) 1.10
Nanotoxicology: in vitro-in vivo dosimetry. Environ Health Perspect (2012) 1.09
Ultrafine carbon particles induce apoptosis and proliferation in rat lung epithelial cells via specific signaling pathways both using EGF-R. Am J Physiol Lung Cell Mol Physiol (2006) 1.05
Systemic effects of inhaled ultrafine particles in two compromised, aged rat strains. Inhal Toxicol (2004) 1.04
Recirculating air filtration significantly reduces exposure to airborne nanoparticles. Environ Health Perspect (2008) 1.03
Activation of pulmonary dendritic cells and Th2-type inflammatory responses on instillation of engineered, environmental diesel emission source or ambient air pollutant particles in vivo. J Innate Immun (2010) 1.03
Validation of an LDH assay for assessing nanoparticle toxicity. Toxicology (2011) 1.03
ECG parameters and exposure to carbon ultrafine particles in young healthy subjects. Inhal Toxicol (2009) 1.02
Induction of chemokines by low-dose intratracheal silica is reduced in TNFR I (p55) null mice. Toxicol Sci (2003) 1.01
A nanoparticle dispersion method for in vitro and in vivo nanotoxicity study. Nanotoxicology (2010) 1.00
Zinc oxide nanoparticles induce necrosis and apoptosis in macrophages in a p47phox- and Nrf2-independent manner. PLoS One (2013) 0.99
On-road exposure to highway aerosols. 2. Exposures of aged, compromised rats. Inhal Toxicol (2004) 0.98
Contrasting macrophage activation by fine and ultrafine titanium dioxide particles is associated with different uptake mechanisms. Part Fibre Toxicol (2011) 0.98
Inflammatory time course after quartz instillation: role of tumor necrosis factor-alpha and particle surface. Am J Respir Cell Mol Biol (2004) 0.97
Early postnatal exposure to ultrafine particulate matter air pollution: persistent ventriculomegaly, neurochemical disruption, and glial activation preferentially in male mice. Environ Health Perspect (2014) 0.97
Comparing inhaled ultrafine versus fine zinc oxide particles in healthy adults: a human inhalation study. Am J Respir Crit Care Med (2005) 0.97
Associations of urban air particulate composition with inflammatory and cytotoxic responses in RAW 246.7 cell line. Inhal Toxicol (2009) 0.97
Neutrophil-derived ROS contribute to oxidative DNA damage induction by quartz particles. Free Radic Biol Med (2010) 0.97
Distinctive toxicity of TiO2 rutile/anatase mixed phase nanoparticles on Caco-2 cells. Chem Res Toxicol (2012) 0.96
Possible genotoxic mechanisms of nanoparticles: criteria for improved test strategies. Nanotoxicology (2010) 0.95
Hydroxyl-radical-dependent DNA damage by ambient particulate matter from contrasting sampling locations. Environ Res (2005) 0.93
Neutrophils augment LPS-mediated pro-inflammatory signaling in human lung epithelial cells. Biochim Biophys Acta (2012) 0.93
Cytogenetic analysis of buccal cells from shoe-workers and pathology and anatomy laboratory workers exposed to n-hexane, toluene, methyl ethyl ketone and formaldehyde. Biomarkers (2002) 0.93
Nanoparticle (NP) uptake by type I alveolar epithelial cells and their oxidant stress response. Nanotoxicology (2009) 0.92
Comparative evaluation of the effects of short-term inhalation exposure to diesel engine exhaust on rat lung and brain. Arch Toxicol (2010) 0.92
Developmental exposure to concentrated ambient particles and preference for immediate reward in mice. Environ Health Perspect (2012) 0.92
The crucial role of particle surface reactivity in respirable quartz-induced reactive oxygen/nitrogen species formation and APE/Ref-1 induction in rat lung. Respir Res (2005) 0.91
Application of an informatics-based decision-making framework and process to the assessment of radiation safety in nanotechnology. Health Phys (2015) 0.91
DNA damage in lung epithelial cells isolated from rats exposed to quartz: role of surface reactivity and neutrophilic inflammation. Carcinogenesis (2002) 0.90
Short-term effects of air pollution: a panel study of blood markers in patients with chronic pulmonary disease. Part Fibre Toxicol (2009) 0.90
Effects of on-road highway aerosol exposures on autonomic responses in aged, spontaneously hypertensive rats. Inhal Toxicol (2007) 0.90
Extraction and quantification of carbon nanotubes in biological matrices with application to rat lung tissue. ACS Nano (2013) 0.89
Oxidant generation and toxicity of size-fractionated ambient particles in human lung epithelial cells. Environ Sci Technol (2010) 0.89
Reactive oxygen species as mediators of membrane-dependent signaling induced by ultrafine particles. Free Radic Biol Med (2010) 0.88
Time course of lung retention and toxicity of inhaled particles: short-term exposure to nano-Ceria. Arch Toxicol (2014) 0.88
Increase of inflammatory markers after indoor renovation activities: the LISA birth cohort study. Pediatr Allergy Immunol (2009) 0.87
Surface-dependent quartz uptake by macrophages: potential role in pulmonary inflammation and lung clearance. Inhal Toxicol (2007) 0.86
Impact of ambient air pollution on the differential white blood cell count in patients with chronic pulmonary disease. Inhal Toxicol (2010) 0.86
Endotoxin potentiates ozone-induced pulmonary chemokine and inflammatory responses. Exp Lung Res (2002) 0.86
Assessing the relevance of in vitro studies in nanotoxicology by examining correlations between in vitro and in vivo data. Toxicology (2012) 0.86
Influence of simulated gastrointestinal conditions on particle-induced cytotoxicity and interleukin-8 regulation in differentiated and undifferentiated Caco-2 cells. Nanotoxicology (2012) 0.86
Oxidant-induced DNA damage by quartz in alveolar epithelial cells. Mutat Res (2002) 0.86
Incorporation of particle size differences between animal studies and human workplace aerosols for deriving exposure limit values. Regul Toxicol Pharmacol (2010) 0.85
Evaluation of apoptosis induced by nanoparticles and fine particles in RAW 264.7 macrophages: facts and artefacts. Toxicol In Vitro (2011) 0.84
Actin plays a crucial role in the phagocytosis and biological response to respirable quartz particles in macrophages. Arch Toxicol (2007) 0.84
Mechanisms of neutrophil-induced DNA damage in respiratory tract epithelial cells. Mol Cell Biochem (2002) 0.84
Particle induced toxicity in relation to transition metal and polycyclic aromatic hydrocarbon contents. Environ Sci Technol (2009) 0.84
Investigation of the cytotoxic and proinflammatory effects of cement dusts in rat alveolar macrophages. Chem Res Toxicol (2009) 0.83
Evaluation of cytotoxic effects and oxidative stress with hydroxyapatite dispersions of different physicochemical properties in rat NR8383 cells and primary macrophages. Toxicol In Vitro (2009) 0.83
Nitrite enhances neutrophil-induced DNA strand breakage in pulmonary epithelial cells by inhibition of myeloperoxidase. Carcinogenesis (2005) 0.82
Surface iron inhibits quartz-induced cytotoxic and inflammatory responses in alveolar macrophages. Chem Res Toxicol (2010) 0.82
Curcumin protects against cytotoxic and inflammatory effects of quartz particles but causes oxidative DNA damage in a rat lung epithelial cell line. Toxicol Appl Pharmacol (2007) 0.81
A comparative study of different in vitro lung cell culture systems to assess the most beneficial tool for screening the potential adverse effects of carbon nanotubes. Toxicol Sci (2013) 0.81
Toxicology of ambient particulate matter. EXS (2012) 0.79
Inhibition of the mitochondrial respiratory chain function abrogates quartz induced DNA damage in lung epithelial cells. Mutat Res (2006) 0.79
Decreased levels of lipid peroxidation-induced DNA damage in the onset of atherogenesis in apolipoprotein E deficient mice. Mutat Res (2007) 0.79
Relation between stressful life events, neuropeptides and cytokines: results from the LISA birth cohort study. Pediatr Allergy Immunol (2008) 0.79
Particles which may occur in food or food packaging can exert cytotoxicity and (oxidative) DNA damage in target cells of the human intestine. Nanotoxicology (2010) 0.78