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Methylation of histone H3R2 by PRMT6 and H3K4 by an MLL complex are mutually exclusive.
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Nature
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2007
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Toward a unified nomenclature for mammalian ADP-ribosyltransferases.
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Trends Biochem Sci
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2010
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3.32
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3
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Substrate-assisted catalysis by PARP10 limits its activity to mono-ADP-ribosylation.
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Mol Cell
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2008
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4
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Stimulation of c-MYC transcriptional activity and acetylation by recruitment of the cofactor CBP.
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EMBO Rep
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2003
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2.21
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5
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The gamma 2 subunit of GABA(A) receptors is required for maintenance of receptors at mature synapses.
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Mol Cell Neurosci
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2003
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2.18
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6
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The gamma2 subunit of GABA(A) receptors is a substrate for palmitoylation by GODZ.
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J Neurosci
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2004
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2.07
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The ins and outs of MYC regulation by posttranslational mechanisms.
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J Biol Chem
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2006
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The c-MYC oncoprotein, the NAMPT enzyme, the SIRT1-inhibitor DBC1, and the SIRT1 deacetylase form a positive feedback loop.
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Proc Natl Acad Sci U S A
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2011
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The GDP-GTP exchange factor collybistin: an essential determinant of neuronal gephyrin clustering.
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J Neurosci
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2004
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1.75
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10
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GODZ-mediated palmitoylation of GABA(A) receptors is required for normal assembly and function of GABAergic inhibitory synapses.
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J Neurosci
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2006
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11
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The regulation of SIRT2 function by cyclin-dependent kinases affects cell motility.
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J Cell Biol
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12
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SIRT2 regulates NF-κB dependent gene expression through deacetylation of p65 Lys310.
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J Cell Sci
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2010
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Macrodomain-containing proteins are new mono-ADP-ribosylhydrolases.
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Nat Struct Mol Biol
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2013
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GABAergic control of adult hippocampal neurogenesis in relation to behavior indicative of trait anxiety and depression states.
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J Neurosci
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2007
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1.41
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15
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Enzymatic site-specific functionalization of protein methyltransferase substrates with alkynes for click labeling.
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Angew Chem Int Ed Engl
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2010
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1.37
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16
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Phosphorylation by Cdk2 is required for Myc to repress Ras-induced senescence in cotransformation.
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Proc Natl Acad Sci U S A
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2009
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1.36
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17
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Distinct gamma2 subunit domains mediate clustering and synaptic function of postsynaptic GABAA receptors and gephyrin.
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J Neurosci
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2005
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1.36
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18
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A balanced chromosomal translocation disrupting ARHGEF9 is associated with epilepsy, anxiety, aggression, and mental retardation.
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Hum Mutat
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2009
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1.32
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19
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PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation.
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Oncogene
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2005
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1.30
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20
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CD73/ecto-5'-nucleotidase protects against vascular inflammation and neointima formation.
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Circulation
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2006
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1.27
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21
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Signaling by IL-31 and functional consequences.
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Eur J Cell Biol
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2011
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1.25
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22
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Regulation of the transcription factor FOXM1c by Cyclin E/CDK2.
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FEBS Lett
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2006
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1.16
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23
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A human T-cell lymphotropic virus type 1 enhancer of Myc transforming potential stabilizes Myc-TIP60 transcriptional interactions.
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Mol Cell Biol
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2005
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1.15
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24
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GABAergic terminals are required for postsynaptic clustering of dystrophin but not of GABA(A) receptors and gephyrin.
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J Neurosci
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2002
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1.10
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25
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The protein kinase DYRK1A phosphorylates the splicing factor SF3b1/SAP155 at Thr434, a novel in vivo phosphorylation site.
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BMC Biochem
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2006
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1.10
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26
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The human trithorax protein hASH2 functions as an oncoprotein.
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Cancer Res
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2008
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1.08
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27
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The transcription factor Yin Yang 1 is an activator of BACE1 expression.
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J Neurochem
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2006
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1.08
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28
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ARTD10 substrate identification on protein microarrays: regulation of GSK3β by mono-ADP-ribosylation.
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Cell Commun Signal
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2013
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1.08
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A selenium-based click AdoMet analogue for versatile substrate labeling with wild-type protein methyltransferases.
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Chembiochem
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2012
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1.07
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SH3TC2, a protein mutant in Charcot-Marie-Tooth neuropathy, links peripheral nerve myelination to endosomal recycling.
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Brain
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2010
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1.06
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31
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Macrodomain-containing proteins: regulating new intracellular functions of mono(ADP-ribosyl)ation.
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Nat Rev Mol Cell Biol
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2013
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IL-31 regulates differentiation and filaggrin expression in human organotypic skin models.
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J Allergy Clin Immunol
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2011
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1.02
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Regulation of NF-κB signalling by the mono-ADP-ribosyltransferase ARTD10.
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Nat Commun
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2013
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1.01
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34
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Learning how to read ADP-ribosylation.
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Cell
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2009
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A peptide-based target screen implicates the protein kinase CK2 in the global regulation of caspase signaling.
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Sci Signal
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2011
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0.98
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Recognition of mono-ADP-ribosylated ARTD10 substrates by ARTD8 macrodomains.
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Structure
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2013
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0.97
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Cytokines and the skin barrier.
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Int J Mol Sci
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2013
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YY1 binding to a subset of p53 DNA-target sites regulates p53-dependent transcription.
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Biochem Biophys Res Commun
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2004
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Caspase-dependent regulation and subcellular redistribution of the transcriptional modulator YY1 during apoptosis.
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Mol Cell Biol
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2005
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Dynamic subcellular localization of the mono-ADP-ribosyltransferase ARTD10 and interaction with the ubiquitin receptor p62.
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Cell Commun Signal
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2012
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Regulation of sirtuin function by posttranslational modifications.
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Front Pharmacol
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Expanding functions of intracellular resident mono-ADP-ribosylation in cell physiology.
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FEBS J
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The transcription factor YY1 is a substrate for Polo-like kinase 1 at the G2/M transition of the cell cycle.
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PLoS One
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2011
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H3K4 dimethylation in hepatocellular carcinoma is rare compared with other hepatobiliary and gastrointestinal carcinomas and correlates with expression of the methylase Ash2 and the demethylase LSD1.
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Hum Pathol
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2009
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Progress in the function and regulation of ADP-Ribosylation.
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Sci Signal
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2011
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Activity-based assay for human mono-ADP-ribosyltransferases ARTD7/PARP15 and ARTD10/PARP10 aimed at screening and profiling inhibitors.
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Eur J Pharm Sci
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2013
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Repression of in vivo growth of Myc/Ras transformed tumor cells by Mad1.
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Oncogene
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2002
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Y-box protein 1 mediates PDGF-B effects in mesangioproliferative glomerular disease.
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49
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Mad1 function in cell proliferation and transcriptional repression is antagonized by cyclin E/CDK2.
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J Biol Chem
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2005
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Revisiting a selection of target genes for the hematopoietic transcription factor c-Myb using chromatin immunoprecipitation and c-Myb knockdown.
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2007
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Targeted inactivation of a developmentally regulated neural plectin isoform (plectin 1c) in mice leads to reduced motor nerve conduction velocity.
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J Biol Chem
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2009
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Autoradiographic imaging of altered synaptic alphabetagamma2 and extrasynaptic alphabeta GABAA receptors in a genetic mouse model of anxiety.
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Neurochem Int
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2004
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Caspase-dependent cleavage of the mono-ADP-ribosyltransferase ARTD10 interferes with its pro-apoptotic function.
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FEBS J
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Regulation of the MAD1 promoter by G-CSF.
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Nucleic Acids Res
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Phosphorylation of the transcription factor YY1 by CK2α prevents cleavage by caspase 7 during apoptosis.
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Mol Cell Biol
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2011
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Knockdown of GABA(A) receptor signaling in GnRH neurons has minimal effects upon fertility.
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Endocrinology
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Overlap of the gene encoding the novel poly(ADP-ribose) polymerase Parp10 with the plectin 1 gene and common use of exon sequences.
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Genomics
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2005
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Caspase-8-mediated PAR-4 cleavage is required for TNFα-induced apoptosis.
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Paradox of sonic hedgehog (SHH) transcriptional regulation: Alternative transcription initiation overrides the effect of downstream promoter DNA methylation.
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2011
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Yersinia enterocolitica YopT and Clostridium difficile toxin B induce expression of GILZ in epithelial cells.
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Inhibition of apoptosis by MAD1 is mediated by repression of the PTEN tumor suppressor gene.
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Function and regulation of the mono-ADP-ribosyltransferase ARTD10.
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Characterization of a human TSPY promoter.
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Cytokines and inflammation.
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TGFβ1 enhances MAD1 expression and stimulates promoter-bound Pol II phosphorylation: basic functions of C/EBP, SP and SMAD3 transcription factors.
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BMC Mol Biol
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IL-31 expression by inflammatory cells is preferentially elevated in atopic dermatitis.
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Acta Derm Venereol
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