Published in Metabolism on June 30, 2010
The association between metabolic syndrome and the risk of prostate cancer, high-grade prostate cancer, advanced prostate cancer, prostate cancer-specific mortality and biochemical recurrence. J Exp Clin Cancer Res (2013) 1.08
Sex-specific mouse liver gene expression: genome-wide analysis of developmental changes from pre-pubertal period to young adulthood. Biol Sex Differ (2012) 0.98
Pleiotropy between genetic markers of obesity and risk of prostate cancer. Cancer Epidemiol Biomarkers Prev (2013) 0.78
Effects of Pueraria lobata Root Ethanol Extract on Adipogenesis and Lipogenesis During 3T3-L1 Differentiation into Adipocytes. Toxicol Res (2015) 0.77
Transcription factor TIP27 regulates glucose homeostasis and insulin sensitivity in a PI3-kinase/Akt-dependent manner in mice. Int J Obes (Lond) (2015) 0.76
JAZF1/SUZ12 gene fusion in endometrial stromal sarcomas. Orphanet J Rare Dis (2016) 0.75
Are genetic variations the most important risk factors for development of hepatocellular carcinoma? J Gastroenterol (2015) 0.75
Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle. J Biol Chem (2002) 9.76
The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation. Immunity (2008) 7.60
Mutations in SYNGAP1 in autosomal nonsyndromic mental retardation. N Engl J Med (2009) 3.88
Hyperspectral remote sensing of foliar nitrogen content. Proc Natl Acad Sci U S A (2012) 3.87
Direct measure of the de novo mutation rate in autism and schizophrenia cohorts. Am J Hum Genet (2010) 3.69
Meta-analysis of traditional Chinese patent medicine for ischemic stroke. Stroke (2007) 3.46
Commensal bacteria regulate Toll-like receptor 3-dependent inflammation after skin injury. Nat Med (2009) 3.32
Steatosis and liver cancer in transgenic mice expressing the structural and nonstructural proteins of hepatitis C virus. Gastroenterology (2002) 3.02
A five-microRNA signature identified from genome-wide serum microRNA expression profiling serves as a fingerprint for gastric cancer diagnosis. Eur J Cancer (2010) 2.84
Cell cycle regulation in the postmitotic neuron: oxymoron or new biology? Nat Rev Neurosci (2007) 2.75
Apatinib for chemotherapy-refractory advanced metastatic gastric cancer: results from a randomized, placebo-controlled, parallel-arm, phase II trial. J Clin Oncol (2013) 2.69
Aging-associated reductions in AMP-activated protein kinase activity and mitochondrial biogenesis. Cell Metab (2007) 2.64
Chinese physicians and their smoking knowledge, attitudes, and practices. Am J Prev Med (2007) 2.32
Methods of the International Tobacco Control (ITC) China Survey. Tob Control (2009) 2.30
BRAF inhibition increases tumor infiltration by T cells and enhances the antitumor activity of adoptive immunotherapy in mice. Clin Cancer Res (2012) 2.28
PD-1 blockade enhances T-cell migration to tumors by elevating IFN-γ inducible chemokines. Cancer Res (2012) 2.23
The ubiquitin ligase RNF5 regulates antiviral responses by mediating degradation of the adaptor protein MITA. Immunity (2009) 2.21
Safety of blind percutaneous liver biopsy in obese children: a retrospective analysis. J Clin Gastroenterol (2010) 2.12
Insulin acutely decreases hepatic fatty acid synthase activity. Cell Metab (2005) 1.99
Neural synchronization during face-to-face communication. J Neurosci (2012) 1.99
Blockade of EphA receptor tyrosine kinase activation inhibits vascular endothelial cell growth factor-induced angiogenesis. Mol Cancer Res (2002) 1.96
Tissue inhibitor of metalloproteinase-3 downregulation in lymphangioleiomyomatosis: potential consequence of abnormal serum response factor expression. Am J Respir Cell Mol Biol (2003) 1.93
CEACAM1 regulates insulin clearance in liver. Nat Genet (2002) 1.92
Forecasting global generation of obsolete personal computers. Environ Sci Technol (2010) 1.89
Extensive DNA damage-induced sumoylation contributes to replication and repair and acts in addition to the mec1 checkpoint. Mol Cell (2012) 1.70
The Relationship between auxin transport and maize branching. Plant Physiol (2008) 1.68
Findings from 2010 Global Adult Tobacco Survey: implementation of MPOWER policy in China. Biomed Environ Sci (2010) 1.65
Acupoint-specific fMRI patterns in human brain. Neurosci Lett (2005) 1.57
Surgical technical performance scores are predictors of late mortality and unplanned reinterventions in infants after cardiac surgery. J Thorac Cardiovasc Surg (2012) 1.57
Down-regulation of myeloid cell leukemia-1 through inhibiting Erk/Pin 1 pathway by sorafenib facilitates chemosensitization in breast cancer. Cancer Res (2008) 1.56
Phase I study of aurora A kinase inhibitor MLN8237 in advanced solid tumors: safety, pharmacokinetics, pharmacodynamics, and bioavailability of two oral formulations. Clin Cancer Res (2012) 1.56
Transforming growth factor-beta (TGF- 1) down-regulates Notch3 in fibroblasts to promote smooth muscle gene expression. J Biol Chem (2007) 1.52
Effect of intravenous proton pump inhibitor regimens and timing of endoscopy on clinical outcomes of peptic ulcer bleeding. J Gastroenterol Hepatol (2012) 1.51
Systematic review of the effectiveness of hyperbaric oxygenation therapy in the management of chronic diabetic foot ulcers. Mayo Clin Proc (2013) 1.50
Demethylation of TNFSF7 contributes to CD70 overexpression in CD4+ T cells from patients with systemic sclerosis. Clin Immunol (2012) 1.48
Clinical analysis of salivary gland tumor cases in West China in past 50 years. Oral Oncol (2007) 1.48
Genetic sophistication of human complement components C4A and C4B and RP-C4-CYP21-TNX (RCCX) modules in the major histocompatibility complex. Am J Hum Genet (2002) 1.47
Association of TLR4 gene non-missense single nucleotide polymorphisms with rheumatoid arthritis in Chinese Han population. Rheumatol Int (2012) 1.45
Posttreatment plasma VEGF levels may be associated with the overall survival of patients with advanced non-small cell lung cancer treated with bevacizumab plus chemotherapy. Med Oncol (2011) 1.44
Retracted Meta-analysis of the effect of percutaneous coronary intervention on chronic total coronary occlusions. J Cardiothorac Surg (2014) 1.43
Experimental realization of self-guiding unidirectional electromagnetic edge states. Phys Rev Lett (2011) 1.42
Expression changes of ionic channels in early phase of cultured rat atrial myocytes induced by rapid pacing. J Cardiothorac Surg (2013) 1.42
Population-based survey of secondhand smoke exposure in China. Biomed Environ Sci (2010) 1.40
Potential benefits of co-transplanting autologous adult stem cells together with human embryonic stem cells or their differentiated derivatives. Ann Clin Lab Sci (2005) 1.39
Activation of the nonreceptor protein tyrosine kinase Ack by multiple extracellular stimuli. Proc Natl Acad Sci U S A (2006) 1.37
Electrophilic tuning of the chemoprotective natural product sulforaphane. Proc Natl Acad Sci U S A (2010) 1.37
Microsaccadic efficacy and contribution to foveal and peripheral vision. J Neurosci (2012) 1.36
Ephrin-B1 transduces signals to activate integrin-mediated migration, attachment and angiogenesis. J Cell Sci (2002) 1.36
Targeted expression of BikDD eradicates pancreatic tumors in noninvasive imaging models. Cancer Cell (2007) 1.35
Severe epilepsy resulting from genetic interaction between Scn2a and Kcnq2. Hum Mol Genet (2006) 1.34
Reprogramming of EBV-immortalized B-lymphocyte cell lines into induced pluripotent stem cells. Blood (2011) 1.34
Integrative metabolic regulation of peripheral tissue fatty acid oxidation by the SRC kinase family member Fyn. Cell Metab (2007) 1.34
Inflammation and diabetic retinal microvascular complications. J Cardiovasc Dis Res (2011) 1.33
Structural and functional analysis of VQ motif-containing proteins in Arabidopsis as interacting proteins of WRKY transcription factors. Plant Physiol (2012) 1.32
Nuclear localization of Cdk5 is a key determinant in the postmitotic state of neurons. Proc Natl Acad Sci U S A (2008) 1.31
Phase II study of MLN8237 (alisertib), an investigational Aurora A kinase inhibitor, in patients with platinum-resistant or -refractory epithelial ovarian, fallopian tube, or primary peritoneal carcinoma. Gynecol Oncol (2012) 1.31
Inhibition of VEGF-dependent multistage carcinogenesis by soluble EphA receptors. Neoplasia (2003) 1.30
Urea-induced ROS generation causes insulin resistance in mice with chronic renal failure. J Clin Invest (2009) 1.27
Transduction of tumor-specific T cells with CXCR2 chemokine receptor improves migration to tumor and antitumor immune responses. Clin Cancer Res (2010) 1.27
Protein-protein interactions in the regulation of WRKY transcription factors. Mol Plant (2013) 1.26
Advancing cell biology and functional genomics in maize using fluorescent protein-tagged lines. Plant Physiol (2009) 1.25
Effects of culture conditions and bone morphogenetic protein 2 on extent of chondrogenesis from human embryonic stem cells. Stem Cells (2007) 1.25
A spontaneous mutation involving Kcnq2 (Kv7.2) reduces M-current density and spike frequency adaptation in mouse CA1 neurons. J Neurosci (2006) 1.24
Association study of genetic variants in eight genes/loci with type 2 diabetes in a Han Chinese population. BMC Med Genet (2010) 1.24
Circulating betatrophin levels are increased in patients with type 2 diabetes and associated with insulin resistance. J Clin Endocrinol Metab (2015) 1.24
Architecture of the Smc5/6 Complex of Saccharomyces cerevisiae Reveals a Unique Interaction between the Nse5-6 Subcomplex and the Hinge Regions of Smc5 and Smc6. J Biol Chem (2009) 1.23
NSAIDs prevent, but do not reverse, neuronal cell cycle reentry in a mouse model of Alzheimer disease. J Clin Invest (2009) 1.23
High-fat diet-induced adipocyte cell death occurs through a cyclophilin D intrinsic signaling pathway independent of adipose tissue inflammation. Diabetes (2011) 1.22
Plasma FGF-21 levels in type 2 diabetic patients with ketosis. Diabetes Res Clin Pract (2008) 1.21
Urine podocyte mRNAs, proteinuria, and progression in human glomerular diseases. J Am Soc Nephrol (2013) 1.20
Climate shaped the worldwide distribution of human mitochondrial DNA sequence variation. Proc Biol Sci (2009) 1.20
Loss of has-miR-337-3p expression is associated with lymph node metastasis of human gastric cancer. J Exp Clin Cancer Res (2013) 1.19
The high and low molecular weight forms of hyaluronan have distinct effects on CD44 clustering. J Biol Chem (2012) 1.18
A high-throughput screening system for Arabidopsis transcription factors and its application to Med25-dependent transcriptional regulation. Mol Plant (2011) 1.18
SUMOylation regulates telomere length homeostasis by targeting Cdc13. Nat Struct Mol Biol (2011) 1.17
Loss of viability during freeze-thaw of intact and adherent human embryonic stem cells with conventional slow-cooling protocols is predominantly due to apoptosis rather than cellular necrosis. J Biomed Sci (2005) 1.17
Association between metabolic syndrome and risk of stroke: a meta-analysis of cohort studies. Cerebrovasc Dis (2008) 1.16
The genus Epimedium: an ethnopharmacological and phytochemical review. J Ethnopharmacol (2011) 1.16
Canine distemper outbreak in rhesus monkeys, China. Emerg Infect Dis (2011) 1.14
Incidence and risk factors for venous thromboembolism in critically ill children after trauma. J Trauma (2010) 1.14
Concern Directing stem cells into the keratinocyte lineage in vitro. Exp Dermatol (2005) 1.12
WU and KI polyomavirus present in the respiratory tract of children, but not in immunocompetent adults. J Clin Virol (2008) 1.12
A rostrocaudal muscular dystrophy caused by a defect in choline kinase beta, the first enzyme in phosphatidylcholine biosynthesis. J Biol Chem (2005) 1.12
IL-2 therapy promotes suppressive ICOS+ Treg expansion in melanoma patients. J Clin Invest (2014) 1.12
Antitumor activity of selective MEK1/2 inhibitor AZD6244 in combination with PI3K/mTOR inhibitor BEZ235 in gefitinib-resistant NSCLC xenograft models. J Exp Clin Cancer Res (2014) 1.12
Genetic and epidemiologic characterization of HIV-1 infection In Liaoning Province, China. J Acquir Immune Defic Syndr (2010) 1.11
Tonoplast calcium sensors CBL2 and CBL3 control plant growth and ion homeostasis through regulating V-ATPase activity in Arabidopsis. Cell Res (2012) 1.11
Chiral Brønsted acid-catalyzed direct asymmetric Mannich reaction. J Am Chem Soc (2007) 1.10
Large conductance, Ca2+-activated K+ channels (BKCa) and arteriolar myogenic signaling. FEBS Lett (2010) 1.10
An efficient synthesis of hydantoins via sustainable integration of coupled domino processes. Org Lett (2010) 1.10
Spatial distribution and mechanical function of elastin in resistance arteries: a role in bearing longitudinal stress. Arterioscler Thromb Vasc Biol (2011) 1.09
Isoprenoid biosynthesis as a drug target: bisphosphonate inhibition of Escherichia coli K12 growth and synergistic effects of fosmidomycin. J Med Chem (2006) 1.09
Determining the one, two, three, or four long and short loci of human complement C4 in a major histocompatibility complex haplotype encoding C4A or C4B proteins. Am J Hum Genet (2002) 1.09
Chemoresistance to gemcitabine in hepatoma cells induces epithelial-mesenchymal transition and involves activation of PDGF-D pathway. Oncotarget (2013) 1.09
Phase I study of MLN8237--investigational Aurora A kinase inhibitor--in relapsed/refractory multiple myeloma, non-Hodgkin lymphoma and chronic lymphocytic leukemia. Invest New Drugs (2013) 1.09
Studies of aberrant phyllotaxy1 mutants of maize indicate complex interactions between auxin and cytokinin signaling in the shoot apical meristem. Plant Physiol (2009) 1.09