Published in Neuroscientist on June 25, 2010
Glia and pain: is chronic pain a gliopathy? Pain (2013) 2.21
Palmitoylethanolamide, a naturally occurring disease-modifying agent in neuropathic pain. Inflammopharmacology (2013) 1.61
Dry needling - peripheral and central considerations. J Man Manip Ther (2011) 1.45
Neuronal and microglial mechanisms of neuropathic pain. Mol Brain (2011) 1.41
Traumatic brain injury, neuroinflammation, and post-traumatic headaches. Headache (2013) 1.19
Spinal TLR4 mediates the transition to a persistent mechanical hypersensitivity after the resolution of inflammation in serum-transferred arthritis. Pain (2011) 1.17
Vascular endothelial cells mediate mechanical stimulation-induced enhancement of endothelin hyperalgesia via activation of P2X2/3 receptors on nociceptors. J Neurosci (2013) 1.04
Pathophysiology of astroglial purinergic signalling. Purinergic Signal (2012) 1.03
The expression of spinal methyl-CpG-binding protein 2, DNA methyltransferases and histone deacetylases is modulated in persistent pain states. Mol Pain (2012) 1.00
Mast cells, glia and neuroinflammation: partners in crime? Immunology (2014) 0.99
Dynamic changes to the endocannabinoid system in models of chronic pain. Philos Trans R Soc Lond B Biol Sci (2012) 0.96
Stress-induced visceral pain: toward animal models of irritable-bowel syndrome and associated comorbidities. Front Psychiatry (2015) 0.96
New perspectives in the diagnosis and management of enteric neuropathies. Nat Rev Gastroenterol Hepatol (2013) 0.92
The effect of intrathecal administration of glial activation inhibitors on dorsal horn BDNF overexpression and hind paw mechanical allodynia in spinal nerve ligated rats. J Neural Transm (Vienna) (2011) 0.91
Mast cell-glia axis in neuroinflammation and therapeutic potential of the anandamide congener palmitoylethanolamide. Philos Trans R Soc Lond B Biol Sci (2012) 0.91
Behavioral evidence for the differential regulation of p-p38 MAPK and p-NF-κB in rats with trigeminal neuropathic pain. Mol Pain (2011) 0.90
Chemokine CCL2 and its receptor CCR2 in the medullary dorsal horn are involved in trigeminal neuropathic pain. J Neuroinflammation (2012) 0.89
Combination Drug Therapy for Pain following Chronic Spinal Cord Injury. Pain Res Treat (2012) 0.87
Estrogen in cycling rats alters gene expression in the temporomandibular joint, trigeminal ganglia and trigeminal subnucleus caudalis/upper cervical cord junction. J Cell Physiol (2011) 0.87
Role of spinal P2Y6 and P2Y11 receptors in neuropathic pain in rats: possible involvement of glial cells. Mol Pain (2014) 0.86
Benefits of exercise intervention in reducing neuropathic pain. Front Cell Neurosci (2014) 0.85
σ1 receptors activate astrocytes via p38 MAPK phosphorylation leading to the development of mechanical allodynia in a mouse model of neuropathic pain. Br J Pharmacol (2014) 0.84
CCL-1 in the spinal cord contributes to neuropathic pain induced by nerve injury. Cell Death Dis (2013) 0.84
Micronized palmitoylethanolamide reduces the symptoms of neuropathic pain in diabetic patients. Pain Res Treat (2014) 0.84
Kynurenic acid modulates experimentally induced inflammation in the trigeminal ganglion. J Headache Pain (2015) 0.83
Unraveling the pathogenesis of HIV peripheral neuropathy: insights from a simian immunodeficiency virus macaque model. ILAR J (2014) 0.81
Multivariate proteomic analysis of the cerebrospinal fluid of patients with peripheral neuropathic pain and healthy controls - a hypothesis-generating pilot study. J Pain Res (2015) 0.80
Extracellular microvesicles from astrocytes contain functional glutamate transporters: regulation by protein kinase C and cell activation. Front Cell Neurosci (2013) 0.80
The Emerging Role of Spinal Dynorphin in Chronic Pain: A Therapeutic Perspective. Annu Rev Pharmacol Toxicol (2016) 0.80
Neurochemical analysis of primary motor cortex in chronic low back pain. Brain Sci (2012) 0.80
Neuroinflammation and virus replication in the spinal cord of simian immunodeficiency virus-infected macaques. J Neuropathol Exp Neurol (2015) 0.80
Opioid administration following spinal cord injury: implications for pain and locomotor recovery. Exp Neurol (2013) 0.79
Evidence of both systemic inflammation and neuroinflammation in fibromyalgia patients, as assessed by a multiplex protein panel applied to the cerebrospinal fluid and to plasma. J Pain Res (2017) 0.78
Identification of cytokines and signaling proteins differentially regulated by sumatriptan/naproxen. Headache (2011) 0.78
Percept of the duration of a vibrotactile stimulus is altered by changing its amplitude. Front Syst Neurosci (2015) 0.78
Crosstalk between astrocytic CXCL12 and microglial CXCR4 contributes to the development of neuropathic pain. Mol Pain (2016) 0.77
ATP release mechanisms of endothelial cell-mediated stimulus-dependent hyperalgesia. J Pain (2014) 0.77
Ligustilide Ameliorates Inflammatory Pain and Inhibits TLR4 Upregulation in Spinal Astrocytes Following Complete Freund's Adjuvant Peripheral Injection. Cell Mol Neurobiol (2015) 0.77
Luteal serum BDNF and HSP70 levels in women with premenstrual dysphoric disorder. Eur Arch Psychiatry Clin Neurosci (2013) 0.76
Advances in cortical modulation of pain. J Pain Res (2013) 0.76
Perioperative nerve blockade: clues from the bench. Anesthesiol Res Pract (2011) 0.76
Minocycline attenuates bone cancer pain in rats by inhibiting NF-κB in spinal astrocytes. Acta Pharmacol Sin (2016) 0.76
Spinal Cord T-Cell Infiltration in the Rat Spared Nerve Injury Model: A Time Course Study. Int J Mol Sci (2016) 0.76
Toll-like receptor 4 contributes to chronic itch, alloknesis, and spinal astrocyte activation in male mice. Pain (2016) 0.76
A critical time window for the analgesic effect of central histamine in the partial sciatic ligation model of neuropathic pain. J Neuroinflammation (2016) 0.75
Retracted The novel therapeuthic targets in the treatment of chronic pain. Transl Med UniSa (2012) 0.75
Unconventional Role of Caspase-6 in Spinal Microglia Activation and Chronic Pain. Mediators Inflamm (2017) 0.75
Ganglionic GFAP (+) glial Gq-GPCR signaling enhances heart functions in vivo. JCI Insight (2017) 0.75
Radiologic and histological observations in experimental T1-T12 dorsal arthrodesis: A qualitative description of T1-T12 segment and other body parts involved, between prepubertal age and skeletal maturityxs. Indian J Orthop (2016) 0.75
Close encounters of the third kind: evidence for contact with TNF-alpha. Pain (2010) 0.75
Elevated levels of calcitonin gene-related peptide in upper spinal cord promotes sensitization of primary trigeminal nociceptive neurons. Neuroscience (2016) 0.75
Glial activation in the collagenase model of nociception associated with osteoarthritis. Mol Pain (2017) 0.75
The effect of psychological interventions on the prevention of chronic pain in adults: a systematic review protocol. Syst Rev (2017) 0.75
BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain. Nature (2005) 7.07
P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury. Nature (2003) 6.04
Pathological and protective roles of glia in chronic pain. Nat Rev Neurosci (2009) 5.53
The neuropathic pain triad: neurons, immune cells and glia. Nat Neurosci (2007) 5.38
GLIA: listening and talking to the synapse. Nat Rev Neurosci (2001) 4.67
Neuropathic pain and spinal microglia: a big problem from molecules in "small" glia. Trends Neurosci (2005) 4.01
Distinct roles of matrix metalloproteases in the early- and late-phase development of neuropathic pain. Nat Med (2008) 3.83
MAP kinase and pain. Brain Res Rev (2008) 3.75
p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain. J Neurosci (2003) 3.72
Inhibition of microglial activation attenuates the development but not existing hypersensitivity in a rat model of neuropathy. J Pharmacol Exp Ther (2003) 3.69
Minocycline attenuates mechanical allodynia and proinflammatory cytokine expression in rat models of pain facilitation. Pain (2005) 3.34
Satellite glial cells in sensory ganglia: from form to function. Brain Res Brain Res Rev (2005) 3.12
p38 MAPK, microglial signaling, and neuropathic pain. Mol Pain (2007) 2.72
JNK-induced MCP-1 production in spinal cord astrocytes contributes to central sensitization and neuropathic pain. J Neurosci (2009) 2.64
Activated microglia contribute to the maintenance of chronic pain after spinal cord injury. J Neurosci (2006) 2.60
Immune and glial cell factors as pain mediators and modulators. Exp Neurol (2005) 2.30
Murine models of inflammatory, neuropathic and cancer pain each generates a unique set of neurochemical changes in the spinal cord and sensory neurons. Neuroscience (2000) 2.28
Gliogenesis and glial pathology in depression. CNS Neurol Disord Drug Targets (2007) 2.26
Fractalkine (CX3CL1) and fractalkine receptor (CX3CR1) distribution in spinal cord and dorsal root ganglia under basal and neuropathic pain conditions. Eur J Neurosci (2004) 2.11
Altered expression and uptake activity of spinal glutamate transporters after nerve injury contribute to the pathogenesis of neuropathic pain in rats. J Neurosci (2003) 2.10
The effect of site and type of nerve injury on spinal glial activation and neuropathic pain behavior. Exp Neurol (1999) 1.98
Quantitative real-time RT-PCR assessment of spinal microglial and astrocytic activation markers in a rat model of neuropathic pain. Neurochem Int (2004) 1.95
TNF-alpha and TNF-alpha receptor type 1 upregulation in glia and neurons after peripheral nerve injury: studies in murine DRG and spinal cord. Spine (Phila Pa 1976) (2004) 1.93
Evidence that exogenous and endogenous fractalkine can induce spinal nociceptive facilitation in rats. Eur J Neurosci (2004) 1.89
Role of the CX3CR1/p38 MAPK pathway in spinal microglia for the development of neuropathic pain following nerve injury-induced cleavage of fractalkine. Brain Behav Immun (2006) 1.88
The involvement of glial cells in the development of morphine tolerance. Neurosci Res (2001) 1.87
Role of spinal microglia in rat models of peripheral nerve injury and inflammation. Eur J Pain (2006) 1.70
Acute peripheral inflammation induces moderate glial activation and spinal IL-1beta expression that correlates with pain behavior in the rat. Brain Res (1999) 1.70
Staining of glial fibrillary acidic protein (GFAP) in lumbar spinal cord increases following a sciatic nerve constriction injury. Brain Res (1991) 1.67
Intravenous paclitaxel administration in the rat induces a peripheral sensory neuropathy characterized by macrophage infiltration and injury to sensory neurons and their supporting cells. Exp Neurol (2006) 1.67
Partial peripheral nerve injury leads to activation of astroglia and microglia which parallels the development of allodynic behavior. Glia (1998) 1.58
An evolving cellular pathology occurs in dorsal root ganglia, peripheral nerve and spinal cord following intravenous administration of paclitaxel in the rat. Brain Res (2007) 1.49
Extracellular signal-regulated kinase-regulated microglia-neuron signaling by prostaglandin E2 contributes to pain after spinal cord injury. J Neurosci (2007) 1.49
Spinal glutamate uptake is critical for maintaining normal sensory transmission in rat spinal cord. Pain (2005) 1.44
Satellite glial cells in sensory ganglia: their possible contribution to inflammatory pain. Brain Behav Immun (2007) 1.41
Possible role of spinal astrocytes in maintaining chronic pain sensitization: review of current evidence with focus on bFGF/JNK pathway. Neuron Glia Biol (2006) 1.41
Spinal glial activation in a new rat model of bone cancer pain produced by prostate cancer cell inoculation of the tibia. Pain (2005) 1.37
NMDA Receptors in glia. Neuroscientist (2007) 1.33
Do glial cells control pain? Neuron Glia Biol (2007) 1.30
The problem of astrocyte identity. Neurochem Int (2004) 1.29
Satellite-cell-derived nerve growth factor and neurotrophin-3 are involved in noradrenergic sprouting in the dorsal root ganglia following peripheral nerve injury in the rat. Eur J Neurosci (1999) 1.29
Nerve conduction blockade in the sciatic nerve prevents but does not reverse the activation of p38 mitogen-activated protein kinase in spinal microglia in the rat spared nerve injury model. Anesthesiology (2007) 1.29
The liberation of fractalkine in the dorsal horn requires microglial cathepsin S. J Neurosci (2009) 1.26
Constitutive expression of CCR2 chemokine receptor and inhibition by MCP-1/CCL2 of GABA-induced currents in spinal cord neurones. J Neurochem (2005) 1.26
Stereological and somatotopic analysis of the spinal microglial response to peripheral nerve injury. Brain Behav Immun (2006) 1.24
Direct evidence for spinal cord microglia in the development of a neuropathic pain-like state in mice. J Neurochem (2006) 1.20
Brain-derived neurotrophic factor drives the changes in excitatory synaptic transmission in the rat superficial dorsal horn that follow sciatic nerve injury. J Physiol (2009) 1.19
New evidence for the involvement of spinal fractalkine receptor in pain facilitation and spinal glial activation in rat model of monoarthritis. Pain (2006) 1.17
MMPs initiate Schwann cell-mediated MBP degradation and mechanical nociception after nerve damage. Mol Cell Neurosci (2008) 1.16
Age-related changes in the spinal cord microglial and astrocytic response profile to nerve injury. Brain Behav Immun (2006) 1.15
Gliopathic pain: when satellite glial cells go bad. Neuroscientist (2009) 1.12
Activation of p38 mitogen-activated protein kinase in spinal microglia contributes to incision-induced mechanical allodynia. Anesthesiology (2009) 1.12
Cell-type specific activation of p38 and ERK mediates calcitonin gene-related peptide involvement in tolerance to morphine-induced analgesia. FASEB J (2009) 1.11
GFAP immunoreactivity in trigeminal ganglion satellite cells after tooth injury in rats. Exp Neurol (1995) 1.11
Dissociation of spinal microglia morphological activation and peripheral inflammation in inflammatory pain models. J Neuroimmunol (2007) 1.10
Differential activation of spinal cord glial cells in murine models of neuropathic and cancer pain. Eur J Pain (2008) 1.09
Brain derived neurotrophic factor (BDNF) contributes to the pain hypersensitivity following surgical incision in the rats. Mol Pain (2008) 1.05
Spinal cord histopathological alterations in a patient with longstanding complex regional pain syndrome. Brain Behav Immun (2008) 1.04
Morphological and electrophysiological changes in mouse dorsal root ganglia after partial colonic obstruction. Am J Physiol Gastrointest Liver Physiol (2005) 1.03
Neurotrophins from dorsal root ganglia trigger allodynia after spinal nerve injury in rats. Eur J Neurosci (2000) 1.03
Spinal cord glia and interleukin-1 do not appear to mediate persistent allodynia induced by intramuscular acidic saline in rats. J Pain (2006) 1.03
Metabotropic glutamate receptors in glial cells. Neurochem Res (2008) 1.02
The effect of activated microglia on astrogliosis parameters in astrocyte cultures. Brain Res (2006) 0.99
Chemokine network in the nervous system: a new target for pain relief. Curr Med Chem (2008) 0.98
Unilateral focal burn injury is followed by long-lasting bilateral allodynia and neuronal hyperexcitability in spinal cord dorsal horn. J Pain (2009) 0.98
Markers of nerve tissue injury in the cerebrospinal fluid in patients with lumbar disc herniation and sciatica. Spine (Phila Pa 1976) (1999) 0.97
Chronic pain-induced emotional dysfunction is associated with astrogliosis due to cortical delta-opioid receptor dysfunction. J Neurochem (2006) 0.96
Up-regulation of TNFalpha in DRG satellite cells following lumbar facet joint injury in rats. Eur Spine J (2006) 0.94
Trigeminal ganglion neuronal activity and glial fibrillary acidic protein immunoreactivity after inferior alveolar nerve crush in the adult rat. Pain (1997) 0.93
Neuropathic pain in aged rats: behavioral responses and astrocytic activation. Exp Brain Res (2001) 0.92
Effect of substance P on cytokine production by human astrocytic cells and blood mononuclear cells: characterization of novel tachykinin receptor antagonists. FEBS Lett (1996) 0.89
Chronic pain-induced astrocyte activation in the cingulate cortex with no change in neural or glial differentiation from neural stem cells in mice. Neurosci Lett (2007) 0.89
Delayed sympathetic dependence in the spared nerve injury (SNI) model of neuropathic pain. Mol Pain (2007) 0.89
GABA inhibits endozepine release from cultured rat astrocytes. Glia (1999) 0.86
Upregulation of the GABA-transporter GAT-1 in the spinal cord contributes to pain behaviour in experimental neuropathy. Neurosci Lett (2008) 0.86
Behavioural and morphological evidence for the involvement of glial cell activation in delta opioid receptor function: implications for the development of opioid tolerance. Mol Pain (2007) 0.84
Hyperalgesic effects of gamma-aminobutyric acid transporter I in mice. J Neurosci Res (2003) 0.82
Increased expression of gamma-aminobutyric acid transporters GAT-1 and GAT-3 in the spinal trigeminal nucleus after facial carrageenan injections. Pain (2001) 0.82
Somatostatin down-regulates the expression and release of endozepines from cultured rat astrocytes via distinct receptor subtypes. J Neurochem (2005) 0.81
GFAP and Fos immunoreactivity in lumbo-sacral spinal cord and medulla oblongata after chronic colonic inflammation in rats. World J Gastroenterol (2005) 0.81
PACAP stimulates biosynthesis and release of endozepines from rat astrocytes. Ann N Y Acad Sci (2006) 0.79
Serum S100beta protein in children with acute recurrent headache: a potentially useful marker for migraine. Headache (2005) 0.77
Systemic administration of propentofylline does not attenuate morphine tolerance in non-injured rodents. Neurosci Lett (2005) 0.76
Resolvins RvE1 and RvD1 attenuate inflammatory pain via central and peripheral actions. Nat Med (2010) 4.23
Distinct roles of matrix metalloproteases in the early- and late-phase development of neuropathic pain. Nat Med (2008) 3.83
p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain. J Neurosci (2003) 3.72
p38 MAPK, microglial signaling, and neuropathic pain. Mol Pain (2007) 2.72
JNK-induced MCP-1 production in spinal cord astrocytes contributes to central sensitization and neuropathic pain. J Neurosci (2009) 2.64
VGLUT2-dependent glutamate release from nociceptors is required to sense pain and suppress itch. Neuron (2010) 2.54
Phosphatidylinositol 3-kinase activates ERK in primary sensory neurons and mediates inflammatory heat hyperalgesia through TRPV1 sensitization. J Neurosci (2004) 2.41
Chemokines, neuronal-glial interactions, and central processing of neuropathic pain. Pharmacol Ther (2010) 2.27
Nociceptors are interleukin-1beta sensors. J Neurosci (2008) 2.26
Blocking caspase activity prevents transsynaptic neuronal apoptosis and the loss of inhibition in lamina II of the dorsal horn after peripheral nerve injury. J Neurosci (2005) 2.16
Suppression of inflammatory and neuropathic pain by uncoupling CRMP-2 from the presynaptic Ca²⁺ channel complex. Nat Med (2011) 2.11
Removal of GABAergic inhibition facilitates polysynaptic A fiber-mediated excitatory transmission to the superficial spinal dorsal horn. Mol Cell Neurosci (2003) 2.02
Role of the CX3CR1/p38 MAPK pathway in spinal microglia for the development of neuropathic pain following nerve injury-induced cleavage of fractalkine. Brain Behav Immun (2006) 1.88
Targeting astrocyte signaling for chronic pain. Neurotherapeutics (2010) 1.88
Toll-like receptor 7 mediates pruritus. Nat Neurosci (2010) 1.86
Macrophage proresolving mediator maresin 1 stimulates tissue regeneration and controls pain. FASEB J (2012) 1.86
Assessment and analysis of mechanical allodynia-like behavior induced by spared nerve injury (SNI) in the mouse. Pain (2006) 1.79
Chronic morphine induces downregulation of spinal glutamate transporters: implications in morphine tolerance and abnormal pain sensitivity. J Neurosci (2002) 1.78
A novel tool for the assessment of pain: validation in low back pain. PLoS Med (2009) 1.75
Disruption of ErbB receptor signaling in adult non-myelinating Schwann cells causes progressive sensory loss. Nat Neurosci (2003) 1.75
DRAGON: a member of the repulsive guidance molecule-related family of neuronal- and muscle-expressed membrane proteins is regulated by DRG11 and has neuronal adhesive properties. J Neurosci (2004) 1.64
Emerging role of Toll-like receptors in the control of pain and itch. Neurosci Bull (2012) 1.60
Development of neuropathic pain in the rat spared nerve injury model is not prevented by a peripheral nerve block. Anesthesiology (2003) 1.59
Resolving TRPV1- and TNF-α-mediated spinal cord synaptic plasticity and inflammatory pain with neuroprotectin D1. J Neurosci (2011) 1.58
Sodium channel beta2 subunits regulate tetrodotoxin-sensitive sodium channels in small dorsal root ganglion neurons and modulate the response to pain. J Neurosci (2006) 1.51
Neurokinin-1 receptor enhances TRPV1 activity in primary sensory neurons via PKCepsilon: a novel pathway for heat hyperalgesia. J Neurosci (2007) 1.50
Neuronal apoptosis associated with morphine tolerance: evidence for an opioid-induced neurotoxic mechanism. J Neurosci (2002) 1.47
c-Fos and pERK, which is a better marker for neuronal activation and central sensitization after noxious stimulation and tissue injury? Open Pain J (2009) 1.46
Hsp27 upregulation and phosphorylation is required for injured sensory and motor neuron survival. Neuron (2002) 1.46
Intracellular signaling in primary sensory neurons and persistent pain. Neurochem Res (2008) 1.44
TLR3 deficiency impairs spinal cord synaptic transmission, central sensitization, and pruritus in mice. J Clin Invest (2012) 1.44
Peripheral axonal injury results in reduced mu opioid receptor pre- and post-synaptic action in the spinal cord. Pain (2005) 1.41
Possible role of spinal astrocytes in maintaining chronic pain sensitization: review of current evidence with focus on bFGF/JNK pathway. Neuron Glia Biol (2006) 1.41
Recombinant adeno-associated virus serotype 6 (rAAV2/6)-mediated gene transfer to nociceptive neurons through different routes of delivery. Mol Pain (2009) 1.39
Computer-aided Discovery of a New Nav1.7 Inhibitor for Treatment of Pain and Itch. Anesthesiology (2020) 1.38
JAK-STAT3 pathway regulates spinal astrocyte proliferation and neuropathic pain maintenance in rats. Brain (2011) 1.34
TNF-α contributes to spinal cord synaptic plasticity and inflammatory pain: distinct role of TNF receptor subtypes 1 and 2. Pain (2010) 1.31
Endogenous tumor necrosis factor alpha (TNFalpha) requires TNF receptor type 2 to generate heat hyperalgesia in a mouse cancer model. J Neurosci (2008) 1.30
Do glial cells control pain? Neuron Glia Biol (2007) 1.30
Upregulation of the voltage-gated sodium channel beta2 subunit in neuropathic pain models: characterization of expression in injured and non-injured primary sensory neurons. J Neurosci (2005) 1.29
Nerve conduction blockade in the sciatic nerve prevents but does not reverse the activation of p38 mitogen-activated protein kinase in spinal microglia in the rat spared nerve injury model. Anesthesiology (2007) 1.29
Resolvin D2 is a potent endogenous inhibitor for transient receptor potential subtype V1/A1, inflammatory pain, and spinal cord synaptic plasticity in mice: distinct roles of resolvin D1, D2, and E1. J Neurosci (2011) 1.27
Peripheral noxious stimulation induces phosphorylation of the NMDA receptor NR1 subunit at the PKC-dependent site, serine-896, in spinal cord dorsal horn neurons. Eur J Neurosci (2004) 1.27
GDNF and NGF released by synthetic guidance channels support sciatic nerve regeneration across a long gap. Eur J Neurosci (2002) 1.25
Microglia: a promising target for treating neuropathic and postoperative pain, and morphine tolerance. J Formos Med Assoc (2011) 1.24
Upregulation of spinal cannabinoid-1-receptors following nerve injury enhances the effects of Win 55,212-2 on neuropathic pain behaviors in rats. Pain (2003) 1.22
Activation of JNK pathway in persistent pain. Neurosci Lett (2008) 1.19
Microglia and spinal cord synaptic plasticity in persistent pain. Neural Plast (2013) 1.17
Transcriptional and functional profiles of voltage-gated Na(+) channels in injured and non-injured DRG neurons in the SNI model of neuropathic pain. Mol Cell Neurosci (2007) 1.16
Antidepressants for the treatment of chronic pain. Drugs (2008) 1.14
Bradykinin enhances AMPA and NMDA receptor activity in spinal cord dorsal horn neurons by activating multiple kinases to produce pain hypersensitivity. J Neurosci (2008) 1.13
A feed-forward spinal cord glycinergic neural circuit gates mechanical allodynia. J Clin Invest (2013) 1.13
Activation of extracellular signal-regulated kinase in the anterior cingulate cortex contributes to the induction and expression of affective pain. J Neurosci (2009) 1.13
Extracellular caspase-6 drives murine inflammatory pain via microglial TNF-α secretion. J Clin Invest (2014) 1.12
Activation of p38 mitogen-activated protein kinase in spinal microglia contributes to incision-induced mechanical allodynia. Anesthesiology (2009) 1.12
Organization of intralaminar and translaminar neuronal connectivity in the superficial spinal dorsal horn. J Neurosci (2009) 1.11
Distinct ASIC currents are expressed in rat putative nociceptors and are modulated by nerve injury. J Physiol (2006) 1.10
Chemokine contribution to neuropathic pain: respective induction of CXCL1 and CXCR2 in spinal cord astrocytes and neurons. Pain (2013) 1.10
Bradykinin produces pain hypersensitivity by potentiating spinal cord glutamatergic synaptic transmission. J Neurosci (2005) 1.10
Spinal injection of TNF-α-activated astrocytes produces persistent pain symptom mechanical allodynia by releasing monocyte chemoattractant protein-1. Glia (2010) 1.09
Loss of NR1 subunit of NMDARs in primary sensory neurons leads to hyperexcitability and pain hypersensitivity: involvement of Ca(2+)-activated small conductance potassium channels. J Neurosci (2013) 1.09
Astrocytic CX43 hemichannels and gap junctions play a crucial role in development of chronic neuropathic pain following spinal cord injury. Glia (2012) 1.08
5,6-EET is released upon neuronal activity and induces mechanical pain hypersensitivity via TRPA1 on central afferent terminals. J Neurosci (2012) 1.03
Induction of CB1 cannabinoid receptor by inflammation in primary afferent neurons facilitates antihyperalgesic effect of peripheral CB1 agonist. Pain (2006) 1.03
Light touch induces ERK activation in superficial dorsal horn neurons after inflammation: involvement of spinal astrocytes and JNK signaling in touch-evoked central sensitization and mechanical allodynia. J Neurochem (2010) 1.00
Neuroprotectin/protectin D1 protects against neuropathic pain in mice after nerve trauma. Ann Neurol (2013) 1.00
Dysregulation of voltage-gated sodium channels by ubiquitin ligase NEDD4-2 in neuropathic pain. J Clin Invest (2013) 0.99
Is endogenous D-serine in the rostral anterior cingulate cortex necessary for pain-related negative affect? J Neurochem (2006) 0.97
New insights into the mechanisms of itch: are pain and itch controlled by distinct mechanisms? Pflugers Arch (2013) 0.97
Reverse transcription quantitative real-time polymerase chain reaction reference genes in the spared nerve injury model of neuropathic pain: validation and literature search. BMC Res Notes (2013) 0.96
Selective inhibition of JNK with a peptide inhibitor attenuates pain hypersensitivity and tumor growth in a mouse skin cancer pain model. Exp Neurol (2009) 0.94
Voltage-gated sodium channel expression in mouse DRG after SNI leads to re-evaluation of projections of injured fibers. Mol Pain (2014) 0.93
Resolvin E1 inhibits neuropathic pain and spinal cord microglial activation following peripheral nerve injury. J Neuroimmune Pharmacol (2012) 0.93
CXCL13 drives spinal astrocyte activation and neuropathic pain via CXCR5. J Clin Invest (2016) 0.92
β1- and β3- voltage-gated sodium channel subunits modulate cell surface expression and glycosylation of Nav1.7 in HEK293 cells. Front Cell Neurosci (2013) 0.92
Differential wiring of local excitatory and inhibitory synaptic inputs to islet cells in rat spinal lamina II demonstrated by laser scanning photostimulation. J Physiol (2007) 0.91
Different effects of opioid and cannabinoid receptor agonists on C-fiber-induced extracellular signal-regulated kinase activation in dorsal horn neurons in normal and spinal nerve-ligated rats. J Pharmacol Exp Ther (2005) 0.91
Peripheral inflammation induces up-regulation of TRPV2 expression in rat DRG. Pain (2005) 0.91
Treating triple-negative breast cancer by a combination of rapamycin and cyclophosphamide: an in vivo bioluminescence imaging study. Eur J Cancer (2010) 0.91