Proteome-wide dysregulation by PRA1 depletion delineates a role of PRA1 in lipid transport and cell migration.

PubWeight™: 0.80‹?›

🔗 View Article (PMC 3047168)

Published in Mol Cell Proteomics on June 30, 2010

Authors

Hao-Ping Liu1, Chih-Ching Wu, Hung-Yi Kao, Yi-Chuan Huang, Ying Liang, Chia-Chun Chen, Jau-Song Yu, Yu-Sun Chang

Author Affiliations

1: Molecular Medicine Research Center, Department of Medical Biotechnology and Laboratory Science, Graduate Institute of Biomedical Sciences, Chang Gung University, Tao-Yuan, Taiwan.

Articles cited by this

Functional rafts in cell membranes. Nature (1997) 38.89

Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search. Anal Chem (2002) 35.30

A statistical model for identifying proteins by tandem mass spectrometry. Anal Chem (2003) 29.58

A human protein-protein interaction network: a resource for annotating the proteome. Cell (2005) 18.97

Parts per million mass accuracy on an Orbitrap mass spectrometer via lock mass injection into a C-trap. Mol Cell Proteomics (2005) 10.60

Protein sensors for membrane sterols. Cell (2006) 8.62

Analysis and validation of proteomic data generated by tandem mass spectrometry. Nat Methods (2007) 5.10

Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers. Proc Natl Acad Sci U S A (1993) 4.56

Cellular cholesterol trafficking and compartmentalization. Nat Rev Mol Cell Biol (2008) 4.29

iTRAQ underestimation in simple and complex mixtures: "the good, the bad and the ugly". J Proteome Res (2009) 3.61

An assessment of software solutions for the analysis of mass spectrometry based quantitative proteomics data. J Proteome Res (2008) 3.36

Rab proteins mediate Golgi transport of caveola-internalized glycosphingolipids and correct lipid trafficking in Niemann-Pick C cells. J Clin Invest (2002) 3.13

Role of Rab9 GTPase in facilitating receptor recruitment by TIP47. Science (2001) 3.02

Peroxisome-proliferator-activated receptors and cancers: complex stories. Nat Rev Cancer (2004) 2.93

Integrin trafficking and the control of cell migration. Traffic (2006) 2.89

Latent membrane protein 1 of Epstein-Barr virus mimics a constitutively active receptor molecule. EMBO J (1997) 2.87

TIP47: a cargo selection device for mannose 6-phosphate receptor trafficking. Cell (1998) 2.76

Rab GTPases, intracellular traffic and disease. Trends Mol Med (2002) 2.72

Rab GTPases at a glance. J Cell Sci (2007) 2.68

Robust and sensitive iTRAQ quantification on an LTQ Orbitrap mass spectrometer. Mol Cell Proteomics (2008) 2.51

Endocytic recycling pathways: emerging regulators of cell migration. Curr Opin Cell Biol (2006) 2.48

SREBPs: the crossroads of physiological and pathological lipid homeostasis. Trends Endocrinol Metab (2008) 2.21

Yip3 catalyses the dissociation of endosomal Rab-GDI complexes. Nature (2003) 2.15

Vesicular and non-vesicular sterol transport in living cells. The endocytic recycling compartment is a major sterol storage organelle. J Biol Chem (2001) 2.07

The integrin alpha6beta4 functions in carcinoma cell migration on laminin-1 by mediating the formation and stabilization of actin-containing motility structures. J Cell Biol (1997) 2.03

The Epstein-Barr virus oncogene product, latent membrane protein 1, induces the downregulation of E-cadherin gene expression via activation of DNA methyltransferases. Proc Natl Acad Sci U S A (2002) 1.92

Intracellular cholesterol transport. Arterioscler Thromb Vasc Biol (2004) 1.75

PKCepsilon-mediated phosphorylation of vimentin controls integrin recycling and motility. EMBO J (2005) 1.75

Emerging role of RAB GTPases in cancer and human disease. Cancer Res (2005) 1.71

iTRAQ reagent-based quantitative proteomic analysis on a linear ion trap mass spectrometer. J Proteome Res (2007) 1.71

Caveolin-1 promotes tumor progression in an autochthonous mouse model of prostate cancer: genetic ablation of Cav-1 delays advanced prostate tumor development in tramp mice. J Biol Chem (2005) 1.59

Modulation of cellular cholesterol transport and homeostasis by Rab11. Mol Biol Cell (2002) 1.51

Caveolin-1-dependent beta1 integrin endocytosis is a critical regulator of fibronectin turnover. J Cell Sci (2008) 1.49

Epstein-Barr virus latent membrane protein 1: structure and functions. J Biomed Sci (2003) 1.49

Analysis of protein expression in cell microarrays: a tool for antibody-based proteomics. J Histochem Cytochem (2006) 1.45

Cholesterol movement in Niemann-Pick type C cells and in cells treated with amphiphiles. J Biol Chem (2000) 1.45

A web-based tool for in silico biomarker discovery based on tissue-specific protein profiles in normal and cancer tissues. Mol Cell Proteomics (2007) 1.43

Beta-catenin activates a coordinated expression of the proinvasive factors laminin-5 gamma2 chain and MT1-MMP in colorectal carcinomas. Int J Cancer (2004) 1.39

Receptor complementation and mutagenesis reveal SR-BI as an essential HCV entry factor and functionally imply its intra- and extra-cellular domains. PLoS Pathog (2009) 1.36

Cholesterol involvement in the pathogenesis of neurodegenerative diseases. Mol Cell Neurosci (2009) 1.35

Lasker Basic Medical Research Award. The machinery and principles of vesicle transport in the cell. Nat Med (2002) 1.35

Caveolin-1 and regulation of cellular cholesterol homeostasis. Am J Physiol Heart Circ Physiol (2006) 1.33

Sigma-1 receptors bind cholesterol and remodel lipid rafts in breast cancer cell lines. Cancer Res (2007) 1.32

Cancer cell-secreted proteomes as a basis for searching potential tumor markers: nasopharyngeal carcinoma as a model. Proteomics (2005) 1.32

Cholesterol accumulation sequesters Rab9 and disrupts late endosome function in NPC1-deficient cells. J Biol Chem (2006) 1.31

Isolation and characterization of a dual prenylated Rab and VAMP2 receptor. J Biol Chem (1997) 1.26

CD40 and LMP-1 both signal from lipid rafts but LMP-1 assembles a distinct, more efficient signaling complex. EMBO J (2001) 1.24

Effect of cholesterol depletion on exocytosis of alveolar type II cells. Am J Respir Cell Mol Biol (2006) 1.23

Telomerase immortalization upregulates Rab9 expression and restores LDL cholesterol egress from Niemann-Pick C1 late endosomes. J Lipid Res (2002) 1.22

PRA1 inhibits the extraction of membrane-bound rab GTPase by GDI1. J Biol Chem (2000) 1.20

Deficiency of niemann-pick type C-1 protein impairs release of human immunodeficiency virus type 1 and results in Gag accumulation in late endosomal/lysosomal compartments. J Virol (2009) 1.18

Intestinal epithelial restitution. Involvement of specific laminin isoforms and integrin laminin receptors in wound closure of a transformed model epithelium. Am J Pathol (1997) 1.17

Prenylated Rab acceptor protein is a receptor for prenylated small GTPases. J Biol Chem (2001) 1.17

Cellular mechanism of U18666A-mediated apoptosis in cultured murine cortical neurons: bridging Niemann-Pick disease type C and Alzheimer's disease. Cell Signal (2006) 1.16

Quantitative proteomic profiling of prostate cancer reveals a role for miR-128 in prostate cancer. Mol Cell Proteomics (2009) 1.13

A functional role for vimentin intermediate filaments in the metabolism of lipoprotein-derived cholesterol in human SW-13 cells. J Biol Chem (1992) 1.12

PRA isoforms are targeted to distinct membrane compartments. J Biol Chem (2000) 1.12

Interaction cloning and characterization of the cDNA encoding the human prenylated rab acceptor (PRA1). Biochem Biophys Res Commun (1999) 1.07

Integrin alpha 6 beta 4 promotes migration, invasion through Tiam1 upregulation, and subsequent Rac activation. Neoplasia (2008) 1.07

Niemann-Pick C1 protein regulates cholesterol transport to the trans-Golgi network and plasma membrane caveolae. J Lipid Res (2002) 1.06

Envelope glycoprotein cytoplasmic domains from diverse lentiviruses interact with the prenylated Rab acceptor. J Virol (2002) 1.05

Annexin A6-induced alterations in cholesterol transport and caveolin export from the Golgi complex. Traffic (2007) 1.05

Epstein-Barr virus latent membrane protein 1 (CAO) up-regulates VEGF and TGF alpha concomitant with hyperlasia, with subsequent up-regulation of p16 and MMP9. Cancer Res (2005) 1.01

Regulation of the association of alpha 6 beta 4 with vimentin intermediate filaments in endothelial cells. Exp Cell Res (2002) 0.98

Nuclear hormone receptors and cholesterol trafficking: the orphans find a new home. J Mol Med (Berl) (2002) 0.98

Self-assembly is important for TIP47 function in mannose 6-phosphate receptor transport. Traffic (2003) 0.97

Cholesterol controls lipid endocytosis through Rab11. Mol Biol Cell (2007) 0.96

Cranial neural crest recycle surface integrins in a substratum-dependent manner to promote rapid motility. J Cell Biol (2004) 0.94

Discovery of retinoblastoma-associated binding protein 46 as a novel prognostic marker for distant metastasis in nonsmall cell lung cancer by combined analysis of cancer cell secretome and pleural effusion proteome. J Proteome Res (2009) 0.94

PRA1 promotes the intracellular trafficking and NF-kappaB signaling of EBV latent membrane protein 1. EMBO J (2006) 0.92

Reproducibility of subjective immunohistochemical estrogen- and progesterone receptor determination in human endometrium. Pathol Res Pract (1993) 0.92

Peroxisome proliferator-activated receptor alpha controls cellular cholesterol trafficking in macrophages. J Lipid Res (2005) 0.92

Endosomal lipid accumulation in NPC1 leads to inhibition of PKC, hypophosphorylation of vimentin and Rab9 entrapment. Biol Cell (2009) 0.91

U18666A inhibits intracellular cholesterol transport and neurotransmitter release in human neuroblastoma cells. Neurochem Res (1999) 0.91

The Niemann-Pick C1 protein in recycling endosomes of presynaptic nerve terminals. J Lipid Res (2005) 0.90

Interactions of rotavirus VP4 spike protein with the endosomal protein Rab5 and the prenylated Rab acceptor PRA1. J Virol (2003) 0.89

Mesenchymal cells contribute to the synthesis and deposition of the laminin-5 gamma2 chain in the invasive front of oral squamous cell carcinoma. J Mol Histol (2007) 0.87

Decreased keratinocyte motility in skin wound on mice lacking the epidermal fatty acid binding protein gene. Mol Cell Biochem (2006) 0.83

The Epstein-Barr virus: a group 1 carcinogen? Virchows Arch (1999) 0.83

PRAF1: a Golgi complex transmembrane protein that interacts with viruses. Biochem Cell Biol (2006) 0.80

Overexpression of laminin-5 gamma2 chain in clear cell carcinoma of the ovary. Virchows Arch (2007) 0.80

Extra Rabs unsnarl a lipid traffic jam. Nat Med (2002) 0.77

Prenylated Rab acceptor 1 (PRA1) inhibits TCF/beta-catenin signaling by binding to beta-catenin. Biochem Biophys Res Commun (2006) 0.76

Articles by these authors

The role of stem cells in aging. Exp Hematol (2003) 2.13

The Epstein-Barr virus oncogene product, latent membrane protein 1, induces the downregulation of E-cadherin gene expression via activation of DNA methyltransferases. Proc Natl Acad Sci U S A (2002) 1.92

Characterization of Epstein-Barr virus miRNAome in nasopharyngeal carcinoma by deep sequencing. PLoS One (2010) 1.63

Genome-wide association study reveals multiple nasopharyngeal carcinoma-associated loci within the HLA region at chromosome 6p21.3. Am J Hum Genet (2009) 1.53

Candidate serological biomarkers for cancer identified from the secretomes of 23 cancer cell lines and the human protein atlas. Mol Cell Proteomics (2010) 1.52

DNA methylation of the Trip10 promoter accelerates mesenchymal stem cell lineage determination. Biochem Biophys Res Commun (2010) 1.52

Epstein-Barr virus latent membrane protein 1: structure and functions. J Biomed Sci (2003) 1.49

In vitro and in vivo studies of FePt nanoparticles for dual modal CT/MRI molecular imaging. J Am Chem Soc (2010) 1.41

Activation of DNA methyltransferase 1 by EBV LMP1 Involves c-Jun NH(2)-terminal kinase signaling. Cancer Res (2006) 1.38

JMJD5 regulates PKM2 nuclear translocation and reprograms HIF-1α-mediated glucose metabolism. Proc Natl Acad Sci U S A (2013) 1.34

Differences in clinical and laboratory characteristics and disease severity between children and adults with dengue virus infection in Taiwan, 2002. Trans R Soc Trop Med Hyg (2009) 1.33

Cancer cell-secreted proteomes as a basis for searching potential tumor markers: nasopharyngeal carcinoma as a model. Proteomics (2005) 1.32

Selective binding of mannose-encapsulated gold nanoparticles to type 1 pili in Escherichia coli. J Am Chem Soc (2002) 1.21

Cul4A is an oncogene in malignant pleural mesothelioma. J Cell Mol Med (2011) 1.21

Overexpression and elevated serum levels of phosphoglycerate kinase 1 in pancreatic ductal adenocarcinoma. Proteomics (2006) 1.20

Overexpression of CLIC1 in human gastric carcinoma and its clinicopathological significance. Proteomics (2007) 1.20

Leukemia inhibitory factor promotes nasopharyngeal carcinoma progression and radioresistance. J Clin Invest (2013) 1.19

Importin subunit alpha-2 is identified as a potential biomarker for non-small cell lung cancer by integration of the cancer cell secretome and tissue transcriptome. Int J Cancer (2011) 1.19

Epstein-Barr virus BZLF1 gene is activated by transforming growth factor-beta through cooperativity of Smads and c-Jun/c-Fos proteins. J Biol Chem (2002) 1.18

Congenic interval of CD45/Ly-5 congenic mice contains multiple genes that may influence hematopoietic stem cell engraftment. Blood (2009) 1.18

Anthranilic acid-based diamides derivatives incorporating aryl-isoxazoline pharmacophore as potential anticancer agents: design, synthesis and biological evaluation. Eur J Med Chem (2012) 1.18

Detection of rare mutant K-ras DNA in a single-tube reaction using peptide nucleic acid as both PCR clamp and sensor probe. Nucleic Acids Res (2006) 1.16

Chemokine receptor CXCR4 expression in hepatocellular carcinoma patients increases the risk of bone metastases and poor survival. BMC Cancer (2009) 1.16

Gefitinib alone or with concomitant whole brain radiotherapy for patients with brain metastasis from non-small-cell lung cancer: a retrospective study. Asian Pac J Cancer Prev (2012) 1.15

Targeted methylation of two tumor suppressor genes is sufficient to transform mesenchymal stem cells into cancer stem/initiating cells. Cancer Res (2011) 1.15

Mitochondrion-targeted photosensitizer enhances the photodynamic effect-induced mitochondrial dysfunction and apoptosis. Ann N Y Acad Sci (2005) 1.15

Curcumin prevents methylglyoxal-induced oxidative stress and apoptosis in mouse embryonic stem cells and blastocysts. J Cell Physiol (2005) 1.15

Tumour inflammasome-derived IL-1β recruits neutrophils and improves local recurrence-free survival in EBV-induced nasopharyngeal carcinoma. EMBO Mol Med (2012) 1.14

Quantitative relations of acoustic inertial cavitation with sonoporation and cell viability. Ultrasound Med Biol (2006) 1.14

Comparative and targeted proteomic analyses of urinary microparticles from bladder cancer and hernia patients. J Proteome Res (2012) 1.14

Adrenal cystic lesions: a clinicopathological analysis of 25 cases with proposed histogenesis and review of the literature. Endocr Pathol (2008) 1.14

Quantitative proteomics reveals regulation of karyopherin subunit alpha-2 (KPNA2) and its potential novel cargo proteins in nonsmall cell lung cancer. Mol Cell Proteomics (2012) 1.14

Discovery of novel bladder cancer biomarkers by comparative urine proteomics using iTRAQ technology. J Proteome Res (2010) 1.10

Contrast-agent-enhanced ultrasound thermal ablation. Ultrasound Med Biol (2006) 1.09

Identification of collapsin response mediator protein-2 as a potential marker of colorectal carcinoma by comparative analysis of cancer cell secretomes. Proteomics (2008) 1.09

Biological characteristics of fluorescent protein-expressing human hepatocellular carcinoma xenograft model in nude mice. Eur J Gastroenterol Hepatol (2008) 1.09

Subcellular localization of Photofrin determines the death phenotype of human epidermoid carcinoma A431 cells triggered by photodynamic therapy: when plasma membranes are the main targets. J Cell Physiol (2003) 1.07

Identification of MYO18A as a novel interacting partner of the PAK2/betaPIX/GIT1 complex and its potential function in modulating epithelial cell migration. Mol Biol Cell (2009) 1.07

Treatment strategies and prognostic factors of patients with primary germ cell tumors in the mediastinum. J Cancer Res Clin Oncol (2011) 1.06

Identification of PRDX4 and P4HA2 as metastasis-associated proteins in oral cavity squamous cell carcinoma by comparative tissue proteomics of microdissected specimens using iTRAQ technology. J Proteome Res (2011) 1.06

Disrupted topological organization in white matter structural networks in amnestic mild cognitive impairment: relationship to subtype. Radiology (2012) 1.06

miR-29 mediates TGFβ1-induced extracellular matrix synthesis through activation of PI3K-AKT pathway in human lung fibroblasts. J Cell Biochem (2013) 1.06

Quantitative analysis of multivalent interactions of carbohydrate-encapsulated gold nanoparticles with concanavalin A. Chem Commun (Camb) (2003) 1.05

Plasma Epstein-Barr virus DNA concentration and clearance rate as novel prognostic factors for metastatic nasopharyngeal carcinoma. Head Neck (2011) 1.04

Identification of potential bladder cancer markers in urine by abundant-protein depletion coupled with quantitative proteomics. J Proteomics (2013) 1.02

Curcumin inhibits UV irradiation-induced oxidative stress and apoptotic biochemical changes in human epidermoid carcinoma A431 cells. J Cell Biochem (2003) 1.02

Expression of matrix metalloproteinases MMP-2 and MMP-9 in gastric cancer and their relation to claudin-4 expression. Histol Histopathol (2008) 1.01

Inhibition of cell migration by autophosphorylated mammalian sterile 20-like kinase 3 (MST3) involves paxillin and protein-tyrosine phosphatase-PEST. J Biol Chem (2006) 1.01

A novel role for TNFAIP2: its correlation with invasion and metastasis in nasopharyngeal carcinoma. Mod Pathol (2010) 1.01

Macrophage inflammatory protein-3alpha is a novel serum marker for nasopharyngeal carcinoma detection and prediction of treatment outcomes. Clin Cancer Res (2008) 1.01

FeS2 nanocrystal ink as a catalytic electrode for dye-sensitized solar cells. Angew Chem Int Ed Engl (2013) 1.00

Comparison of membrane fraction proteomic profiles of normal and cancerous human colorectal tissues with gel-assisted digestion and iTRAQ labeling mass spectrometry. FEBS J (2010) 1.00

Efficient light harvesting by photon downconversion and light trapping in hybrid ZnS nanoparticles/Si nanotips solar cells. ACS Nano (2010) 1.00

Multiplexed quantification of 63 proteins in human urine by multiple reaction monitoring-based mass spectrometry for discovery of potential bladder cancer biomarkers. J Proteomics (2012) 0.99

Identification of candidate nasopharyngeal carcinoma serum biomarkers by cancer cell secretome and tissue transcriptome analysis: potential usage of cystatin A for predicting nodal stage and poor prognosis. Proteomics (2010) 0.99

Body loadings and health risk assessment of polychlorinated dibenzo-p-dioxins and dibenzofurans at an intensive electronic waste recycling site in China. Environ Sci Technol (2007) 0.99

Investigation of an outbreak of cutaneous anthrax in Banlu village, Lianyungang, China, 2012. Western Pac Surveill Response J (2012) 0.98

MicroRNA-376c inhibits cell proliferation and invasion in osteosarcoma by targeting to transforming growth factor-alpha. DNA Cell Biol (2013) 0.97

Identification of guanylate-binding protein 1 as a potential oral cancer marker involved in cell invasion using omics-based analysis. J Proteome Res (2011) 0.97

Overexpression of a secretory leukocyte protease inhibitor in human gastric cancer. Int J Cancer (2008) 0.97

Glutamate receptor, ionotropic, kainate 2 silencing by DNA hypermethylation possesses tumor suppressor function in gastric cancer. Int J Cancer (2010) 0.97

Epidemiology and clinical manifestations of children with macrolide-resistant Mycoplasma pneumoniae pneumonia in Taiwan. Pediatr Pulmonol (2012) 0.97

Characteristics and Prognostic Analysis of 69 Patients With Pulmonary Sarcomatoid Carcinoma. Am J Clin Oncol (2016) 0.97