Published in Age (Dordr) on July 02, 2010
Midlife muscle strength and human longevity up to age 100 years: a 44-year prospective study among a decedent cohort. Age (Dordr) (2011) 1.25
The genetic pleiotropy of musculoskeletal aging. Front Physiol (2012) 0.85
The genetics of bone mass and susceptibility to bone diseases. Nat Rev Rheumatol (2016) 0.82
Androgen receptor polyglutamine repeat number: models of selection and disease susceptibility. Evol Appl (2012) 0.78
Interaction between bone and muscle in older persons with mobility limitations. Curr Pharm Des (2014) 0.77
Association of Serum Klotho with Loss of Bone Mineral Density and Fracture Risk in Older Adults. J Am Geriatr Soc (2016) 0.75
PREDICTIVE MODELING OF HOSPITAL READMISSION RATES USING ELECTRONIC MEDICAL RECORD-WIDE MACHINE LEARNING: A CASE-STUDY USING MOUNT SINAI HEART FAILURE COHORT. Pac Symp Biocomput (2016) 0.75
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Sci U S A (2009) 54.68
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science (2007) 51.70
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science (2007) 43.16
A common allele on chromosome 9 associated with coronary heart disease. Science (2007) 20.37
A common variant on chromosome 9p21 affects the risk of myocardial infarction. Science (2007) 18.96
Genome-wide association analysis identifies 20 loci that influence adult height. Nat Genet (2008) 16.92
Mutation of the mouse klotho gene leads to a syndrome resembling ageing. Nature (1997) 13.77
Vitamin D deficiency and risk of cardiovascular disease. Circulation (2008) 13.39
Osteoporosis prevention, diagnosis, and therapy. JAMA (2001) 12.60
Intake of vitamin D and risk of type 1 diabetes: a birth-cohort study. Lancet (2001) 10.29
Caloric restriction delays disease onset and mortality in rhesus monkeys. Science (2009) 9.84
Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium: Design of prospective meta-analyses of genome-wide association studies from 5 cohorts. Circ Cardiovasc Genet (2009) 8.42
Vitamin D supplementation and total mortality: a meta-analysis of randomized controlled trials. Arch Intern Med (2007) 7.87
Fall prevention with supplemental and active forms of vitamin D: a meta-analysis of randomised controlled trials. BMJ (2009) 7.64
Common variants in the GDF5-UQCC region are associated with variation in human height. Nat Genet (2008) 7.31
Age, Gene/Environment Susceptibility-Reykjavik Study: multidisciplinary applied phenomics. Am J Epidemiol (2007) 7.06
Bivariate quantitative trait linkage analysis: pleiotropy versus co-incident linkages. Genet Epidemiol (1997) 6.08
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet (2009) 5.81
Testosterone therapy in adult men with androgen deficiency syndromes: an endocrine society clinical practice guideline. J Clin Endocrinol Metab (2006) 5.58
Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies. Nat Genet (2009) 5.32
The heritability of human longevity: a population-based study of 2872 Danish twin pairs born 1870-1900. Hum Genet (1996) 4.90
Leg muscle mass and composition in relation to lower extremity performance in men and women aged 70 to 79: the health, aging and body composition study. J Am Geriatr Soc (2002) 4.55
Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes. Nat Genet (2005) 4.44
Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size. PLoS Genet (2009) 4.24
Bone mass and the risk of breast cancer among postmenopausal women. N Engl J Med (1997) 3.96
Osteocalcin and matrix Gla protein: vitamin K-dependent proteins in bone. Physiol Rev (1989) 3.87
Serum 25-hydroxyvitamin D and colon cancer: eight-year prospective study. Lancet (1989) 3.77
The human phenome project. Nat Genet (2003) 3.75
Skeletal muscle strength as a predictor of all-cause mortality in healthy men. J Gerontol A Biol Sci Med Sci (2002) 3.56
Meta-analysis of age-related gene expression profiles identifies common signatures of aging. Bioinformatics (2009) 3.50
Handgrip strength and cause-specific and total mortality in older disabled women: exploring the mechanism. J Am Geriatr Soc (2003) 3.30
Cumulative biological risk and socio-economic differences in mortality: MacArthur studies of successful aging. Soc Sci Med (2004) 3.11
Joint multipoint linkage analysis of multivariate qualitative and quantitative traits. I. Likelihood formulation and simulation results. Am J Hum Genet (1999) 2.88
Collaborative meta-analysis: associations of 150 candidate genes with osteoporosis and osteoporotic fracture. Ann Intern Med (2009) 2.80
Osteoarthritis of finger joints in Finns aged 30 or over: prevalence, determinants, and association with mortality. Ann Rheum Dis (2003) 2.75
Vitamin D supplementation in early childhood and risk of type 1 diabetes: a systematic review and meta-analysis. Arch Dis Child (2008) 2.70
Physiological factors associated with falls in older community-dwelling women. J Am Geriatr Soc (1994) 2.69
Successful aging. Am J Psychiatry (2001) 2.68
Vitamin D status predicts physical performance and its decline in older persons. J Clin Endocrinol Metab (2007) 2.68
Frailty, fitness and late-life mortality in relation to chronological and biological age. BMC Geriatr (2002) 2.63
Frailty index as a measure of biological age in a Chinese population. J Gerontol A Biol Sci Med Sci (2005) 2.58
Sarcopenia: its assessment, etiology, pathogenesis, consequences and future perspectives. J Nutr Health Aging (2008) 2.54
The genetics of aging. Annu Rev Genomics Hum Genet (2001) 2.48
Ten years of life: Is it a matter of choice? Arch Intern Med (2001) 2.43
Prospective study of dietary protein intake and risk of hip fracture in postmenopausal women. Am J Clin Nutr (1999) 2.41
Phenomics: the systematic study of phenotypes on a genome-wide scale. Neuroscience (2009) 2.38
Effects of a short-term vitamin D and calcium supplementation on body sway and secondary hyperparathyroidism in elderly women. J Bone Miner Res (2000) 2.36
Bone loss and the progression of abdominal aortic calcification over a 25 year period: the Framingham Heart Study. Calcif Tissue Int (2001) 2.34
Genome-wide association with bone mass and geometry in the Framingham Heart Study. BMC Med Genet (2007) 2.32
Serum osteocalcin level is associated with glucose metabolism and atherosclerosis parameters in type 2 diabetes mellitus. J Clin Endocrinol Metab (2008) 2.30
Longevity is moderately heritable in a sample of Danish twins born 1870-1880. J Gerontol (1993) 2.30
Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study. BMC Med Genet (2007) 2.25
Vitamin D and breast cancer risk: the NHANES I Epidemiologic follow-up study, 1971-1975 to 1992. National Health and Nutrition Examination Survey. Cancer Epidemiol Biomarkers Prev (1999) 2.24
In situ detection of 1,25-dihydroxyvitamin D3 receptor in human skeletal muscle tissue. Histochem J (2001) 2.24
"Anti-aging" is an oxymoron. J Gerontol A Biol Sci Med Sci (2004) 2.23
Differential genetic effects of ESR1 gene polymorphisms on osteoporosis outcomes. JAMA (2004) 2.20
Association between insulin-like growth factor I and bone mineral density in older women and men: the Framingham Heart Study. J Clin Endocrinol Metab (1998) 2.14
Association between estrogen receptor alpha gene variation and cardiovascular disease. JAMA (2003) 2.10
Skeletal muscle mass and muscle strength in relation to lower-extremity performance in older men and women. J Am Geriatr Soc (2000) 1.99
Comparing the human and chimpanzee genomes: searching for needles in a haystack. Genome Res (2005) 1.95
Osteoarthritis in the carpometacarpal joint of the thumb. Prevalence and associations with disability and mortality. J Bone Joint Surg Am (2004) 1.94
Heritability of body composition measured by DXA in the diabetes heart study. Obes Res (2005) 1.94
Body fat and skeletal muscle mass in relation to physical disability in very old men and women of the Framingham Heart Study. J Gerontol A Biol Sci Med Sci (1998) 1.92
Genetic influences on muscle strength, lean body mass, and bone mineral density: a twin study. J Bone Miner Res (1997) 1.91
Vitamin D receptor expression in human muscle tissue decreases with age. J Bone Miner Res (2004) 1.89
Progression of aortic calcification is associated with metacarpal bone loss during menopause: a population-based longitudinal study. Arterioscler Thromb Vasc Biol (2000) 1.87
Skeletal muscle and mortality results from the InCHIANTI Study. J Gerontol A Biol Sci Med Sci (2009) 1.86
CHIP deficiency decreases longevity, with accelerated aging phenotypes accompanied by altered protein quality control. Mol Cell Biol (2008) 1.82
Calcium, vitamin D, and the occurrence of colorectal cancer among women. J Natl Cancer Inst (1996) 1.81
A polymorphism in the gene for IGF-I: functional properties and risk for type 2 diabetes and myocardial infarction. Diabetes (2001) 1.76
The genetic influence on radiographic osteoarthritis is site specific at the hand, hip and knee. Rheumatology (Oxford) (2009) 1.73
Genetic determinants of human health span and life span: progress and new opportunities. PLoS Genet (2007) 1.70
Defining the phenotype in human genetic studies: forward genetics and reverse phenotyping. Hum Hered (2004) 1.68
A modular network model of aging. Mol Syst Biol (2007) 1.68
Skeletal muscle fiber quality in older men and women. Am J Physiol Cell Physiol (2000) 1.66
A meta-analysis of four genome-wide association studies of survival to age 90 years or older: the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. J Gerontol A Biol Sci Med Sci (2010) 1.65
Age-related decreases in insulin-like growth factor-I and transforming growth factor-beta in femoral cortical bone from both men and women: implications for bone loss with aging. J Clin Endocrinol Metab (1994) 1.63
The heritability of testosterone: a study of Dutch adolescent twins and their parents. Behav Genet (1998) 1.59
Recent results: biomarkers of aging. Exp Gerontol (2006) 1.58
Disentangling the genetic determinants of human aging: biological age as an alternative to the use of survival measures. J Gerontol A Biol Sci Med Sci (2005) 1.50
A physiologic index of comorbidity: relationship to mortality and disability. J Gerontol A Biol Sci Med Sci (2008) 1.48
Hand grip strength: a phenotype suitable for identifying genetic variants affecting mid- and late-life physical functioning. Genet Epidemiol (2002) 1.46
Osteocalcin levels in diabetic subjects. Calcif Tissue Int (1989) 1.45
Factors that influence peak bone mass formation: a study of calcium balance and the inheritance of bone mass in adolescent females. Am J Clin Nutr (1990) 1.43
Heritability of body size and muscle strength in young adulthood: a study of one million Swedish men. Genet Epidemiol (2008) 1.41
Evidence for familial aggregation of hand, hip, and spine but not knee osteoarthritis in siblings with multiple joint involvement: the GARP study. Ann Rheum Dis (2004) 1.39
Do genetic factors explain associations between muscle strength, lean mass, and bone density? A twin study. Am J Physiol (1996) 1.33
Testosterone action on skeletal muscle. Curr Opin Clin Nutr Metab Care (2004) 1.32
Bone mineral density is a predictor of survival. Calcif Tissue Int (1998) 1.32
Assessment of biological age using a profile of physical parameters. J Gerontol (1980) 1.29
Heritability of maximal isometric muscle strength in older female twins. J Appl Physiol (1985) (2003) 1.27
Powerful bivariate genome-wide association analyses suggest the SOX6 gene influencing both obesity and osteoporosis phenotypes in males. PLoS One (2009) 1.26
Cdc42 GTPase-activating protein deficiency promotes genomic instability and premature aging-like phenotypes. Proc Natl Acad Sci U S A (2007) 1.25
Severity of upper and lower extremity functional limitation: scale development and validation with self-report and performance-based measures of physical function. WHAS Research Group. Women's Health and Aging Study. J Gerontol B Psychol Sci Soc Sci (2001) 1.24
Influence of age, sex, and insulin on osteoblast function: osteoblast dysfunction in diabetes mellitus. J Clin Endocrinol Metab (1995) 1.24
A method for identifying biomarkers of aging and constructing an index of biological age in humans. J Gerontol A Biol Sci Med Sci (2007) 1.23
Patterns and correlates of muscle strength loss in older women. Gerontology (2006) 1.21
Androgen receptor CAG repeat polymorphism is associated with fat-free mass in men. J Appl Physiol (1985) (2004) 1.17
Genome screen for a combined bone phenotype using principal component analysis: the Framingham study. Bone (2004) 1.17
Differential anabolic effects of testosterone and amino acid feeding in older men. J Clin Endocrinol Metab (2003) 1.16