Focus on molecules: syndecan-1.

A thermo-responsive protein treatment for dry eyes. J Control Release (2014) 0.76

Requirement of heparan sulfate for bFGF-mediated fibroblast growth and myoblast differentiation. Science (1991) 5.64

Molecular cloning of syndecan, an integral membrane proteoglycan. J Cell Biol (1989) 2.88

Syndecan-1 regulates alphavbeta3 and alphavbeta5 integrin activation during angiogenesis and is blocked by synstatin, a novel peptide inhibitor. J Exp Med (2009) 1.83

Heparanase deglycanation of syndecan-1 is required for binding of the epithelial-restricted prosecretory mitogen lacritin. J Cell Biol (2006) 1.62

The syndecan-1 ectodomain regulates alphavbeta3 integrin activity in human mammary carcinoma cells. J Cell Biol (2004) 1.91

Essential and separable roles for Syndecan-3 and Syndecan-4 in skeletal muscle development and regeneration. Genes Dev (2004) 1.89

Syndecans in tumor cell adhesion and signaling. Reprod Biol Endocrinol (2004) 1.88

Syndecan-1 regulates alphavbeta3 and alphavbeta5 integrin activation during angiogenesis and is blocked by synstatin, a novel peptide inhibitor. J Exp Med (2009) 1.83

HSulf-1 and HSulf-2 are potent inhibitors of myeloma tumor growth in vivo. J Biol Chem (2005) 1.66

Heparanase deglycanation of syndecan-1 is required for binding of the epithelial-restricted prosecretory mitogen lacritin. J Cell Biol (2006) 1.62

Heparanase-enhanced shedding of syndecan-1 by myeloma cells promotes endothelial invasion and angiogenesis. Blood (2010) 1.61

Spatial and temporal expression of heparan sulfate in mouse development regulates FGF and FGF receptor assembly. J Cell Biol (2003) 1.55

Syndecan-1 regulates alphavbeta5 integrin activity in B82L fibroblasts. J Cell Sci (2006) 1.39

Syndecan-1-mediated cell spreading requires signaling by alphavbeta3 integrins in human breast carcinoma cells. Exp Cell Res (2003) 1.36

Heparan sulfate-related oligosaccharides in ternary complex formation with fibroblast growth factors 1 and 2 and their receptors. J Biol Chem (2006) 1.35

Restricted epithelial proliferation by lacritin via PKCalpha-dependent NFAT and mTOR pathways. J Cell Biol (2006) 1.33

The lacrimal gland transcriptome is an unusually rich source of rare and poorly characterized gene transcripts. Invest Ophthalmol Vis Sci (2005) 1.27

A polymer scaffold for protein oligomerization. J Am Chem Soc (2004) 1.11

Lacritin and other new proteins of the lacrimal functional unit. Exp Eye Res (2008) 1.08

Lacritin, a novel human tear glycoprotein, promotes sustained basal tearing and is well tolerated. Invest Ophthalmol Vis Sci (2011) 1.06

Syndecan-1 couples the insulin-like growth factor-1 receptor to inside-out integrin activation. J Cell Sci (2010) 1.06

Interaction of syndecan and alpha6beta4 integrin cytoplasmic domains: regulation of ErbB2-mediated integrin activation. J Biol Chem (2010) 1.01

Syndecan-1 transmembrane and extracellular domains have unique and distinct roles in cell spreading. J Biol Chem (2003) 0.98

ald of Mycobacterium tuberculosis encodes both the alanine dehydrogenase and the putative glycine dehydrogenase. J Bacteriol (2011) 0.97

Exposure of cryptic domains in the alpha 1-chain of laminin-1 by elastase stimulates macrophages urokinase and matrix metalloproteinase-9 expression. J Biol Chem (2002) 0.96

Syndecan-1 accumulates in lysosomes of poorly differentiated breast carcinoma cells. Matrix Biol (2003) 0.95

Fibroblast growth factor receptor-1 mediates the inhibition of endothelial cell proliferation and the promotion of skeletal myoblast differentiation by SPARC: a role for protein kinase A. J Cell Biochem (2003) 0.94

Regulation of fibroblast growth factor-2 activity by human ovarian cancer tumor endothelium. Clin Cancer Res (2005) 0.92

Lacritin rescues stressed epithelia via rapid forkhead box O3 (FOXO3)-associated autophagy that restores metabolism. J Biol Chem (2013) 0.91

Cell-surface heparan sulfate proteoglycans potentiate chordin antagonism of bone morphogenetic protein signaling and are necessary for cellular uptake of chordin. J Biol Chem (2004) 0.91

Syndecan-1 ectodomain regulates matrix-dependent signaling in human breast carcinoma cells. Exp Cell Res (2004) 0.89

Targeting of heparanase-modified syndecan-1 by prosecretory mitogen lacritin requires conserved core GAGAL plus heparan and chondroitin sulfate as a novel hybrid binding site that enhances selectivity. J Biol Chem (2013) 0.87

Tissue transglutaminase is a negative regulator of monomeric lacritin bioactivity. Invest Ophthalmol Vis Sci (2013) 0.87

Lacritin and the tear proteome as natural replacement therapy for dry eye. Exp Eye Res (2013) 0.87

Tear lacritin levels by age, sex, and time of day in healthy adults. Invest Ophthalmol Vis Sci (2012) 0.86

Organogenesis of the exocrine gland. Dev Biol (2004) 0.84

Detection of prosecretory mitogen lacritin in nonprimate tears primarily as a C-terminal-like fragment. Invest Ophthalmol Vis Sci (2012) 0.84

Dry eye and designer ophthalmics. Optom Vis Sci (2008) 0.84

Mutational analysis of the respiratory nitrate transporter NarK2 of Mycobacterium tuberculosis. PLoS One (2012) 0.83

Transmembrane and extracellular domains of syndecan-1 have distinct functions in regulating lung epithelial migration and adhesion. J Biol Chem (2012) 0.83

Cytoprotective effect of lacritin on human corneal epithelial cells exposed to benzalkonium chloride in vitro. Curr Eye Res (2014) 0.82

Focus on molecules: lacritin. Exp Eye Res (2007) 0.82

Human genome search in celiac disease: mutated gliadin T-cell-like epitope in two human proteins promotes T-cell activation. J Mol Biol (2002) 0.80

Purification and characterization of a recombinant Yersinia pestis V-F1 "Reversed" fusion protein for use as a new subunit vaccine against plague. Protein Expr Purif (2010) 0.79

Yersinia pestis outer membrane type III secretion protein YscC: expression, purification, characterization, and induction of specific antiserum. Protein Expr Purif (2005) 0.78

Conserved regional 3' grouping of rare codons in the coding sequence of ocular prosecretory mitogen lacritin. Invest Ophthalmol Vis Sci (2013) 0.77

Genetic separation of the human lacritin gene ("LACRT") and triple A (Allgrove) syndrome on 12q13. Adv Exp Med Biol (2002) 0.76

Focus on molecules: heparanase. Exp Eye Res (2010) 0.75