PubRank

Todd Waldman

Author PubWeight™ 54.70‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Mutational inactivation of STAG2 causes aneuploidy in human cancer. Science 2011 5.04
2 Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors. EMBO Mol Med 2009 4.68
3 Mutational inactivation of PTPRD in glioblastoma multiforme and malignant melanoma. Cancer Res 2008 2.55
4 Pharmacologic inhibition of cyclin-dependent kinases 4 and 6 arrests the growth of glioblastoma multiforme intracranial xenografts. Cancer Res 2010 2.41
5 Activation of p53-dependent growth suppression in human cells by mutations in PTEN or PIK3CA. Mol Cell Biol 2006 2.34
6 Frequent truncating mutations of STAG2 in bladder cancer. Nat Genet 2013 2.20
7 Integrated genomic analyses identify ERRFI1 and TACC3 as glioblastoma-targeted genes. Oncotarget 2010 1.88
8 Oncogenic beta-catenin is required for bone morphogenetic protein 4 expression in human cancer cells. Cancer Res 2002 1.82
9 The metastasis-associated gene S100A4 is a novel target of beta-catenin/T-cell factor signaling in colon cancer. Gastroenterology 2006 1.73
10 Identification of p18 INK4c as a tumor suppressor gene in glioblastoma multiforme. Cancer Res 2008 1.65
11 Suppression of tumorigenesis and activation of Wnt signaling by bone morphogenetic protein 4 in human cancer cells. Cancer Biol Ther 2004 1.56
12 PTEN gene targeting reveals a radiation-induced size checkpoint in human cancer cells. Cancer Res 2004 1.49
13 B-Raf is dispensable for K-Ras-mediated oncogenesis in human cancer cells. Cancer Res 2004 1.46
14 Radiation-induced Akt activation modulates radioresistance in human glioblastoma cells. Radiat Oncol 2009 1.42
15 Heat shock protein Hsp72 controls oncogene-induced senescence pathways in cancer cells. Mol Cell Biol 2008 1.37
16 p16-Cdk4-Rb axis controls sensitivity to a cyclin-dependent kinase inhibitor PD0332991 in glioblastoma xenograft cells. Neuro Oncol 2012 1.32
17 Deletion of PTEN promotes tumorigenic signaling, resistance to anoikis, and altered response to chemotherapeutic agents in human mammary epithelial cells. Cancer Res 2009 1.29
18 Oncogenic mutations of PIK3CA in human cancers. Curr Top Microbiol Immunol 2010 1.27
19 Proof-of-principle: oncogenic beta-catenin is a valid molecular target for the development of pharmacological inhibitors. Mol Cancer Ther 2002 1.23
20 Sample type bias in the analysis of cancer genomes. Cancer Res 2009 1.22
21 Conspirators in a capital crime: co-deletion of p18INK4c and p16INK4a/p14ARF/p15INK4b in glioblastoma multiforme. Cancer Res 2008 1.19
22 Cooperative interactions of BRAFV600E kinase and CDKN2A locus deficiency in pediatric malignant astrocytoma as a basis for rational therapy. Proc Natl Acad Sci U S A 2012 1.15
23 Mechanistic analysis of a DNA damage-induced, PTEN-dependent size checkpoint in human cells. Mol Cell Biol 2011 1.11
24 Epitope tagging of endogenous genes in diverse human cell lines. Nucleic Acids Res 2008 1.09
25 Transformation of mammary epithelial cells by 3-phosphoinositide- dependent protein kinase-1 activates beta-catenin and c-Myc, and down-regulates caveolin-1. Cancer Res 2003 1.09
26 IDH1(R132) mutation identified in one human melanoma metastasis, but not correlated with metastases to the brain. Biochem Biophys Res Commun 2010 1.08
27 Activated PI3K signaling as an endogenous inducer of p53 in human cancer. Cell Cycle 2007 0.97
28 Glioblastoma cells containing mutations in the cohesin component STAG2 are sensitive to PARP inhibition. Mol Cancer Ther 2013 0.93
29 NHERFs, NEP, MAGUKs, and more: interactions that regulate PTEN. J Cell Biochem 2007 0.93
30 Interaction of the BMPR-IA tumor suppressor with a developmentally relevant splicing factor. Biochem Biophys Res Commun 2004 0.90
31 Identification of mutant K-Ras-dependent phenotypes using a panel of isogenic cell lines. J Biol Chem 2012 0.90
32 Up-regulation of fibroblast growth factor-binding protein, by beta-catenin during colon carcinogenesis. Cancer Res 2003 0.88
33 Lack of inherited mutations of PTPRD in familial melanoma and melanoma-astrocytoma syndrome. Pigment Cell Melanoma Res 2009 0.82
34 A high-throughput screen with isogenic PTEN+/+ and PTEN-/- cells identifies CID1340132 as a novel compound that induces apoptosis in PTEN and PIK3CA mutant human cancer cells. J Biomol Screen 2011 0.81
35 Mutational and functional analysis of the tumor-suppressor PTPRD in human melanoma. Hum Mutat 2014 0.78
36 'Cables' suspends cancer in mice. Cancer Biol Ther 2005 0.77
37 Human somatic cell knockouts reveal determinants of sensitivity and resistance to proteasome inhibitor PS-341. Cancer Biol Ther 2003 0.75