Published in Glia on August 15, 2010
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Genomic estimates of aneuploid content in glioblastoma multiforme and improved classification. Clin Cancer Res (2012) 1.06
A sphingosine kinase inhibitor combined with temozolomide induces glioblastoma cell death through accumulation of dihydrosphingosine and dihydroceramide, endoplasmic reticulum stress and autophagy. Cell Death Dis (2014) 0.96
Roles of sphingosine 1-phosphate on tumorigenesis. World J Biol Chem (2011) 0.89
Extracellular sphingosine-1-phosphate: a novel actor in human glioblastoma stem cell survival. PLoS One (2013) 0.84
Re-configuration of sphingolipid metabolism by oncogenic transformation. Biomolecules (2014) 0.83
Sphingosine and Sphingosine Kinase 1 Involvement in Endocytic Membrane Trafficking. J Biol Chem (2017) 0.75
Comparative analysis of the effects of a sphingosine kinase inhibitor to temozolomide and radiation treatment on glioblastoma cell lines. Cancer Biol Ther (2017) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth. Science (2011) 5.46
Thermotolerance requires refolding of aggregated proteins by substrate translocation through the central pore of ClpB. Cell (2004) 4.90
Enhancing macroautophagy protects against ischemia/reperfusion injury in cardiac myocytes. J Biol Chem (2006) 4.57
Monoclonal antibody specific for IDH1 R132H mutation. Acta Neuropathol (2009) 3.38
Ktu/PF13 is required for cytoplasmic pre-assembly of axonemal dyneins. Nature (2008) 3.28
Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2. Nat Cell Biol (2002) 3.24
Remodelling of VipA/VipB tubules by ClpV-mediated threading is crucial for type VI protein secretion. EMBO J (2009) 3.19
Characterization of R132H mutation-specific IDH1 antibody binding in brain tumors. Brain Pathol (2009) 2.77
Loss of nephrocystin-3 function can cause embryonic lethality, Meckel-Gruber-like syndrome, situs inversus, and renal-hepatic-pancreatic dysplasia. Am J Hum Genet (2008) 2.74
Imaging tumor-stroma interactions during chemotherapy reveals contributions of the microenvironment to resistance. Cancer Cell (2012) 2.61
Assessment of BRAF V600E mutation status by immunohistochemistry with a mutation-specific monoclonal antibody. Acta Neuropathol (2011) 2.53
Nuclear actin and myosin I are required for RNA polymerase I transcription. Nat Cell Biol (2004) 2.49
Construction and characterization of a fluorescently labeled infectious human immunodeficiency virus type 1 derivative. J Virol (2004) 2.24
The Mason-Pfizer monkey virus PPPY and PSAP motifs both contribute to virus release. J Virol (2003) 2.19
CCDC39 is required for assembly of inner dynein arms and the dynein regulatory complex and for normal ciliary motility in humans and dogs. Nat Genet (2010) 2.12
Deletions and point mutations of LRRC50 cause primary ciliary dyskinesia due to dynein arm defects. Am J Hum Genet (2009) 2.10
Specific targeting of tumor angiogenesis by RGD-conjugated ultrasmall superparamagnetic iron oxide particles using a clinical 1.5-T magnetic resonance scanner. Cancer Res (2007) 2.01
Homo- and heterodimerization of APP family members promotes intercellular adhesion. EMBO J (2005) 1.98
Modelling of cell killing due to sparsely ionizing radiation in normoxic and hypoxic conditions and an extension to high LET radiation. Int J Radiat Biol (2013) 1.98
ClpV, a unique Hsp100/Clp member of pathogenic proteobacteria. Biol Chem (2005) 1.92
Spheroid-based engineering of a human vasculature in mice. Nat Methods (2008) 1.90
Nephrocystin specifically localizes to the transition zone of renal and respiratory cilia and photoreceptor connecting cilia. J Am Soc Nephrol (2006) 1.79
The von Hippel-Lindau tumor suppressor protein controls ciliogenesis by orienting microtubule growth. J Cell Biol (2006) 1.66
Mutations in KIF7 link Joubert syndrome with Sonic Hedgehog signaling and microtubule dynamics. J Clin Invest (2011) 1.60
ADAM10-mediated cleavage of L1 adhesion molecule at the cell surface and in released membrane vesicles. FASEB J (2002) 1.58
STIL is required for centriole duplication in human cells. J Cell Sci (2012) 1.56
Molecular mechanism of signal perception and integration by the innate immune sensor retinoic acid-inducible gene-I (RIG-I). J Biol Chem (2011) 1.54
Cep164 mediates vesicular docking to the mother centriole during early steps of ciliogenesis. J Cell Biol (2012) 1.51
Concurrent detection of autolysosome formation and lysosomal degradation by flow cytometry in a high-content screen for inducers of autophagy. BMC Biol (2011) 1.51
Disruption of neuronal autophagy by infected microglia results in neurodegeneration. PLoS One (2008) 1.50
Multiple interactions between RNA polymerase I, TIF-IA and TAF(I) subunits regulate preinitiation complex assembly at the ribosomal gene promoter. EMBO Rep (2002) 1.48
Neph-Nephrin proteins bind the Par3-Par6-atypical protein kinase C (aPKC) complex to regulate podocyte cell polarity. J Biol Chem (2008) 1.43
Autophagy as a protective response to Bnip3-mediated apoptotic signaling in the heart. Autophagy (2006) 1.42
Artesunate activates mitochondrial apoptosis in breast cancer cells via iron-catalyzed lysosomal reactive oxygen species production. J Biol Chem (2010) 1.41
Microcephalin and pericentrin regulate mitotic entry via centrosome-associated Chk1. J Cell Biol (2009) 1.41
Molecular basis for the unique role of the AAA+ chaperone ClpV in type VI protein secretion. J Biol Chem (2011) 1.37
Phosphorylation by casein kinase 2 induces PACS-1 binding of nephrocystin and targeting to cilia. EMBO J (2005) 1.35
Autophagy-A double-edged sword in oncology. Int J Cancer (2009) 1.32
Analysis of prototype foamy virus particle-host cell interaction with autofluorescent retroviral particles. Retrovirology (2010) 1.32
Modulation of serines 17 and 24 in the LC3-interacting region of Bnip3 determines pro-survival mitophagy versus apoptosis. J Biol Chem (2012) 1.29
The LINC-less granulocyte nucleus. Eur J Cell Biol (2008) 1.26
NEPH2 is located at the glomerular slit diaphragm, interacts with nephrin and is cleaved from podocytes by metalloproteinases. J Am Soc Nephrol (2005) 1.19
Characterization of prototype foamy virus gag late assembly domain motifs and their role in particle egress and infectivity. J Virol (2005) 1.18
Novel functions of prototype foamy virus Gag glycine- arginine-rich boxes in reverse transcription and particle morphogenesis. J Virol (2010) 1.17
Unconventional secretion of fibroblast growth factor 2 is mediated by direct translocation across the plasma membrane of mammalian cells. J Biol Chem (2003) 1.17
Danger signaling protein HMGB1 induces a distinct form of cell death accompanied by formation of giant mitochondria. Cancer Res (2010) 1.16
Targeted localization of Inn1, Cyk3 and Chs2 by the mitotic-exit network regulates cytokinesis in budding yeast. J Cell Sci (2010) 1.14
Codon optimization of the human papillomavirus 11 (HPV 11) L1 gene leads to increased gene expression and formation of virus-like particles in mammalian epithelial cells. Virology (2004) 1.13
FXYD3 is overexpressed in pancreatic ductal adenocarcinoma and influences pancreatic cancer cell growth. Int J Cancer (2006) 1.12
Phosphorylation-dependent regulation of the F-BAR protein Hof1 during cytokinesis. Genes Dev (2011) 1.09
Autophagy mediates survival of pancreatic tumour-initiating cells in a hypoxic microenvironment. J Pathol (2012) 1.08
The enhancer of zeste homolog 2 gene contributes to cell proliferation and apoptosis resistance in renal cell carcinoma cells. Int J Cancer (2008) 1.08
Epigenetic upregulation of lncRNAs at 13q14.3 in leukemia is linked to the In Cis downregulation of a gene cluster that targets NF-kB. PLoS Genet (2013) 1.08
Initiation and maturation of cilia-generated flow in newborn and postnatal mouse airway. Am J Physiol Lung Cell Mol Physiol (2009) 1.07
The human granulocyte nucleus: Unusual nuclear envelope and heterochromatin composition. Eur J Cell Biol (2008) 1.06
Alzheimer beta-amyloid homodimers facilitate A beta fibrillization and the generation of conformational antibodies. J Biol Chem (2003) 1.04
TNF-alpha- and TRAIL-resistant glioma cells undergo autophagy-dependent cell death induced by activated microglia. Glia (2009) 1.04
Silica- and alkoxysilane-coated ultrasmall superparamagnetic iron oxide particles: a promising tool to label cells for magnetic resonance imaging. Langmuir (2007) 1.03
Through its nonstructural protein NS1, parvovirus H-1 induces apoptosis via accumulation of reactive oxygen species. J Virol (2010) 1.02
Replication vesicles are load- and choke-points in the hepatitis C virus lifecycle. PLoS Pathog (2013) 1.02
Modulation of MAPK pathways and cell cycle by replicating hepatitis B virus: factors contributing to hepatocarcinogenesis. J Hepatol (2007) 1.01
RGD-labeled USPIO inhibits adhesion and endocytotic activity of alpha v beta3-integrin-expressing glioma cells and only accumulates in the vascular tumor compartment. Radiology (2009) 1.01
NADPH oxidase activation by hyperglycaemia in cardiomyocytes is independent of glucose metabolism but requires SGLT1. Cardiovasc Res (2011) 1.01
The microtubule affinity regulating kinase MARK4 promotes axoneme extension during early ciliogenesis. J Cell Biol (2013) 1.01
Histone deacetylase 10 promotes autophagy-mediated cell survival. Proc Natl Acad Sci U S A (2013) 1.01
Reduction of PTEN and p27kip1 expression correlates with tumor grade in prostate cancer. Analysis in radical prostatectomy specimens and needle biopsies. Virchows Arch (2004) 1.00
Correct capsid assembly mediated by a conserved YXXLGL motif in prototype foamy virus Gag is essential for infectivity and reverse transcription of the viral genome. J Virol (2007) 1.00
Testing for anti-p53 antibodies increases the diagnostic sensitivity of conventional tumor markers. Int J Oncol (2006) 1.00
Microglia isolated from patients with glioma gain antitumor activities on poly (I:C) stimulation. Neuro Oncol (2011) 0.99
Intranucleolar sites of ribosome biogenesis defined by the localization of early binding ribosomal proteins. J Cell Biol (2007) 0.99
Regulation of enterocyte apoptosis by acyl-CoA synthetase 5 splicing. Gastroenterology (2007) 0.98
Anti-CD4-targeted gold nanoparticles induce specific contrast enhancement of peripheral lymph nodes in X-ray computed tomography of live mice. Nano Lett (2010) 0.98
Interaction of 14-3-3 protein with regulator of G protein signaling 7 is dynamically regulated by tumor necrosis factor-alpha. J Biol Chem (2002) 0.98
Circulating fibronectin affects bone matrix, whereas osteoblast fibronectin modulates osteoblast function. J Bone Miner Res (2010) 0.98
Incomplete nonsense-mediated decay of mutant lamin A/C mRNA provokes dilated cardiomyopathy and ventricular tachycardia. J Mol Med (Berl) (2007) 0.97
Orthoretroviral-like prototype foamy virus Gag-Pol expression is compatible with viral replication. Retrovirology (2011) 0.96
Autophagy and cell death signaling following dietary sulforaphane act independently of each other and require oxidative stress in pancreatic cancer. Int J Oncol (2011) 0.95
Multi-parametric analysis and modeling of relationships between mitochondrial morphology and apoptosis. PLoS One (2012) 0.95
Ubiquitination of the prototype foamy virus envelope glycoprotein leader peptide regulates subviral particle release. J Virol (2005) 0.94
N-terminal Gag domain required for foamy virus particle assembly and export. J Virol (2005) 0.94
Glutathione peroxidase 1 activity dictates the sensitivity of glioblastoma cells to oxidative stress. Glia (2012) 0.91
Hepatitis B virus overexpresses suppressor of cytokine signaling-3 (SOCS3) thereby contributing to severity of inflammation in the liver. Virus Res (2009) 0.91
E6/E7 expression of human papillomavirus type 20 (HPV-20) and HPV-27 influences proliferation and differentiation of the skin in UV-irradiated SKH-hr1 transgenic mice. J Virol (2006) 0.91
Antitumoral activity of parvovirus-mediated IL-2 and MCP-3/CCL7 delivery into human pancreatic cancer: implication of leucocyte recruitment. Cancer Immunol Immunother (2012) 0.90
Peptide aptamer-mediated inhibition of target proteins by sequestration into aggresomes. J Biol Chem (2006) 0.90
Enhanced immunogenicity of HPV 16 E7 fusion proteins in DNA vaccination. Virology (2002) 0.90
Expression of MAC30 protein is related to survival and biological variables in primary and metastatic colorectal cancers. Int J Oncol (2007) 0.90
Nup88 (karyoporin) in human malignant neoplasms and dysplasias: correlations of immunostaining of tissue sections, cytologic smears, and immunoblot analysis. Hum Pathol (2002) 0.90
IDH1 R132H mutation is a rare event in myeloproliferative neoplasms as determined by a mutation specific antibody. Haematologica (2010) 0.90
Expression of FXYD-3 is an independent prognostic factor in rectal cancer patients with preoperative radiotherapy. Int J Radiat Oncol Biol Phys (2009) 0.89
Functional characterization of mannose receptor expressed by immunocompetent mouse microglia. Glia (2003) 0.88
Subcellular mislocalization of mutant hepatitis B X proteins contributes to modulation of STAT/SOCS signaling in hepatocellular carcinoma. Intervirology (2009) 0.88
The novel actin/focal adhesion-associated protein MISP is involved in mitotic spindle positioning in human cells. Cell Cycle (2013) 0.88
BLOC1S2 interacts with the HIPPI protein and sensitizes NCH89 glioblastoma cells to apoptosis. Apoptosis (2008) 0.87