New paraherquamide antibiotics with anthelmintic activity.

PubWeight™: 1.17‹?› | Rank: Top 10%

🔗 View Article (PMID 2061192)

Published in J Antibiot (Tokyo) on May 01, 1991

Authors

S E Blanchflower1, R M Banks, J R Everett, B R Manger, C Reading

Author Affiliations

1: SmithKline Beecham Animal Health, Tadworth, Surrey, England.

Articles citing this

Isolation of notoamide E, a key precursor in the biosynthesis of prenylated indole alkaloids in a marine-derived fungus, Aspergillus sp. J Am Chem Soc (2009) 1.32

Fungal origins of the bicyclo[2.2.2]diazaoctane ring system of prenylated indole alkaloids. J Nat Prod (2012) 1.19

Biochemical characterization of NotB as an FAD-dependent oxidase in the biosynthesis of notoamide indole alkaloids. J Am Chem Soc (2011) 1.06

Biosynthetic studies of the notoamides: isotopic synthesis of stephacidin A and incorporation into notoamide B and sclerotiamide. Org Lett (2011) 1.00

Synthesis of notoamide J: a potentially pivotal intermediate in the biosynthesis of several prenylated indole alkaloids. J Org Chem (2010) 0.93

Studies on the Biosynthesis of the Stephacidin and Notoamide Natural Products: A Stereochemical and Genetic Conundrum. Isr J Chem (2011) 0.86

Natural products synthesis: enabling tools to penetrate Nature's secrets of biogenesis and biomechanism. J Org Chem (2011) 0.85

Marine Indole Alkaloids. Mar Drugs (2015) 0.82

Utilizing DART mass spectrometry to pinpoint halogenated metabolites from a marine invertebrate-derived fungus. J Org Chem (2011) 0.81

Studies on Paraherquamide Biosynthesis: Synthesis of Deuterium-Labeled 7-Hydroxy-Pre-Paraherquamide, a Putative Precursor of Paraherquamides A, E & F. Tetrahedron (2009) 0.79

Detection of VM55599 and preparaherquamide from Aspergillus japonicus and Penicillium fellutanum: biosynthetic implications. J Nat Prod (2008) 0.78

Rapid access to spirocyclic oxindole alkaloids: application of the asymmetric palladium-catalyzed [3 + 2] trimethylenemethane cycloaddition. J Am Chem Soc (2013) 0.77

Studies Towards Paraherquamides E & F and Related C-labeled Putative Biosynthetic Intermediates: Stereocontrolled Synthesis of the α-Alkyl-β-Methylproline Ring System. Tetrahedron (2008) 0.76

Paraherquamide e. Acta Crystallogr Sect E Struct Rep Online (2010) 0.75

Articles by these authors

Clavulanic acid: a beta-lactamase-inhiting beta-lactam from Streptomyces clavuligerus. Antimicrob Agents Chemother (1977) 11.58

Naturally-occurring beta-lactamase inhibitors with antibacterial activity. J Antibiot (Tokyo) (1976) 6.48

The inhibition of staphylococcal beta-lactamase by clavulanic acid. Biochem J (1979) 2.30

Transplantation with selected autologous peripheral blood CD34+Thy1+ hematopoietic stem cells (HSCs) in multiple myeloma: impact of HSC dose on engraftment, safety, and immune reconstitution. Exp Hematol (2000) 1.77

beta-Lactamases of Branhamella catarrhalis and their inhibition by clavulanic acid. Antimicrob Agents Chemother (1982) 1.65

Assay of amoxicillin and clavulanic acid, the components of Augmentin, in biological fluids with high-performance liquid chromatography. Antimicrob Agents Chemother (1982) 1.50

The effects of base sequence and dangling bases on the stability of short ribonucleic acid duplexes. Nucleic Acids Symp Ser (1980) 1.42

Holomycin and an antibiotic (MM 19290) related to tunicamycin, metabolites of Streptomyces clavuligerus. J Antibiot (Tokyo) (1979) 1.38

Novel anthelmintic metabolites from an Aspergillus species; the aspergillimides. J Antibiot (Tokyo) (1997) 1.31

The inhibition of beta-lactamases from gram-negative bacteria by clavulanic acid. Biochem J (1981) 1.28

Improved quantitation of minimal residual disease in multiple myeloma using real-time polymerase chain reaction and plasmid-DNA complementarity determining region III standards. Cancer Res (1998) 1.23

Further novel metabolites of the paraherquamide family. J Antibiot (Tokyo) (1993) 1.10

Sensitivity to carbenicillin and ticarcillin, and the beta-lactamases of Pseudomonas aeruginosa in the UK in 1978-79. J Clin Pathol (1980) 1.02

Production of metal dependent beta-lactamases by clinical strains of Bacteroides fragilis isolated before 1987. J Antimicrob Chemother (1996) 1.00

The effects of clavulanic acid and sulbactam on beta-lactamase biosynthesis. J Antimicrob Chemother (1988) 0.97

Inhibition of the beta-lactamases of Branhamella catarrhalis by clavulanic acid and other inhibitors. Drugs (1986) 0.96

High resolution 1H NMR spectroscopic studies on dynamic biochemical processes in incubated human seminal fluid samples. Biochim Biophys Acta (1998) 0.94

A new orally bioavailable synthetic androstene inhibits collagen-induced arthritis in the mouse: androstene hormones as regulators of regulatory T cells. Ann N Y Acad Sci (2007) 0.92

Prostatodynia--physiological characteristics and rational management with muscle relaxants. Br J Urol (1981) 0.91

Adjuvant therapy of melanoma with interferon-alpha-2b is associated with mania and bipolar syndromes. Cancer (2000) 0.88

Familial intraocular malignant melanoma: a case report. Cancer (1978) 0.88

Collection, tumor contamination, and engraftment kinetics of highly purified hematopoietic progenitor cells to support high dose therapy in multiple myeloma. Blood (1998) 0.88

HE3286: a novel synthetic steroid as an oral treatment for autoimmune disease. Ann N Y Acad Sci (2009) 0.87

Inhibition of androstenediol-dependent LNCaP tumour growth by 17alpha-ethynyl-5alpha-androstane-3alpha, 17beta-diol (HE3235). Br J Cancer (2009) 0.86

Adults mourning suicide: self-reported concerns about bereavement, needs for assistance, and help-seeking behavior. Death Stud (2000) 0.86

Thiotepa, busulfan, and cyclophosphamide: a new preparative regimen for autologous marrow or blood stem cell transplantation in high-risk multiple myeloma. Blood (1993) 0.85

Beta-lactamase stability of temocillin. Drugs (1985) 0.85

A novel series of milbemycin antibiotics from Streptomyces strain E225. I. Discovery, fermentation and anthelmintic activity. J Antibiot (Tokyo) (1989) 0.84

Polyclonal hematopoiesis in interferon-induced cytogenetic remissions of chronic myelogenous leukemia. Blood (1992) 0.83

Effect of deoxyribonucleic acid ploidy status on survival of patients with carcinoma of the endometrium. Surg Gynecol Obstet (1992) 0.83

Real-time t(11;14) and t(14;18) PCR assays provide sensitive and quantitative assessments of minimal residual disease (MRD). Leukemia (1999) 0.82

Reproducible pneumonia in gnotobiotic piglets induced with broth cultures of Mycoplasma hyopneumoniae and the effect of animal passage on virulence. Res Vet Sci (1984) 0.82

Chemical-exchange and paramagnetic T2 relaxation agents for water suppression in spin-echo proton nuclear magnetic resonance spectroscopy of biological fluids. Anal Chem (1987) 0.82

Differentiation and maturation of growth factor expanded human hematopoietic progenitors assessed by multidimensional flow cytometry. Leukemia (1992) 0.82

A microassay for the determination of iodide and its application to the measurement of the iodination of proteins and the catalytic activities of iodo compounds. Anal Biochem (1989) 0.82

Synthesis and anthelmintic activity of a series of pyrazino[2,1-a][2]benzazepine derivatives. J Med Chem (1989) 0.81

High-resolution magnetic resonance imaging of arthritic pathology in the rat knee. Skeletal Radiol (1994) 0.81

The pattern of peripheral blood leucocyte changes in mice infected with Nematospiroides dubius. J Helminthol (1985) 0.81

27-O-demethylrapamycin, an immunosuppressant compound produced by a new strain of Streptomyces hygroscopicus. J Antibiot (Tokyo) (1995) 0.80

Anti-inflammatory and immune regulatory properties of 5-androsten-3beta, 17beta-diol (HE2100), and synthetic analogue HE3204: implications for treatment of autoimmune diseases. Ann N Y Acad Sci (2005) 0.80

Therapeutic significance of nocardicin A stimulation of phagocyte function in experimental Pseudomonas aeruginosa infection. Br J Exp Pathol (1983) 0.80

Parameters for the calculation of proton NMR chemical shifts of oligoribonucleotides. J Biomol Struct Dyn (1985) 0.80

Nursery outbreak of scalded-skin syndrome. Scarlatiniform rash due to phage group I Staphylococcus aureus. Am J Dis Child (1976) 0.80

A novel series of milbemycin antibiotics from Streptomyces strain E225. II. Isolation, characterization, structure elucidation and solution conformations. J Antibiot (Tokyo) (1990) 0.79

Improved PCR sequencing with formamide. Trends Genet (1992) 0.79

Cytokine-mobilized peripheral blood CD34+Thy-1+Lin- human hematopoietic stem cells as target cells for transplantation-based gene therapy. Leukemia (1995) 0.78

The beta-lactamase stability of amoxycillin with the beta-lactamase inhibitor, clavulanic acid. J Antimicrob Chemother (1983) 0.78

1H-NMR spectroscopy of biofluids and the investigation of xenobiotic-induced changes in liver biochemistry. J Pharm Biomed Anal (1990) 0.77

Leukemic burden in subpopulations of CD34+ cells isolated from the mobilized peripheral blood of alpha-interferon-resistant or -intolerant patients with chronic myeloid leukemia. Blood (1996) 0.77

Impact of frequency range and input impedance on airway-tissue separation implied from transfer impedance. J Appl Physiol (1985) (1993) 0.77

Induction of the beta-lactamases of a strain of Pseudomonas aeruginosa, Morganella morganii and Enterobacter cloacae. J Antimicrob Chemother (1987) 0.77

Molecular analysis of retroviral transduction in chronic myelogenous leukemia. Hum Gene Ther (1991) 0.77

Graft failure and graft-vs-host disease after subtotal T-cell-depleted marrow transplantation: correlations with marrow hematopoietic and lymphoid subsets. Prog Clin Biol Res (1994) 0.76

Clustering in Hodgkin's disease. Lancet (1973) 0.76

High resolution 1H NMR spectroscopic studies of the metabolism and excretion of ampicillin in rats and amoxycillin in rats and man. J Pharm Pharmacol (1994) 0.76

CD2 expression and the PML-RAR gene. Blood (1993) 0.75

Efficacy of epsiprantel against Echinococcus granulosus infections in dogs. Res Vet Sci (1990) 0.75

Hydatid disease screening: Sanpete County, Utah, 1971-1976. Am J Trop Med Hyg (1978) 0.75

Psychophysiological reactivity in migraine following biofeedback. Headache (1984) 0.75

Visualisation of subchondral erosion in rat monoarticular arthritis by magnetic resonance imaging. Skeletal Radiol (1995) 0.75

Use of two retroviral markers to test relative contribution of marrow and peripheral blood autologous cells to recovery after preparative therapy. The University of Texas M.D. Anderson Cancer Center. Division of Medicine. Hum Gene Ther (1993) 0.75

Letter: Down's syndrome, leukaemia and maternal thiamine deficiency. Med J Aust (1976) 0.75

19F NMR spectroscopy study of the metabolites of flucloxacillin in rat urine. J Pharm Pharmacol (1985) 0.75

Sympathetic nervous system and dysfunction of the lower urinary tract. Clin Sci (Lond) (1986) 0.75

The effects of clavulanic acid sulbactam on induction of class 1 beta-lactamase. J Chemother (1989) 0.75

Hot flushes are induced by thermogenic stimuli. Br J Urol (1989) 0.75

Imagery in phobic subjects: a psychophysiological study. Behav Res Ther (1985) 0.75

Biological characterization of stem cell present in mobilized peripheral blood of CML patients. Bone Marrow Transplant (1994) 0.75

Letter: Latent pernicious anaemia. Med J Aust (1975) 0.75

Further novel milbemycin antibiotics from Streptomyces sp. E225. Fermentation, isolation and structure elucidation. J Antibiot (Tokyo) (1996) 0.75

Segmental motion in pseudomonic acid A: a carbon-13 spin-lattice relaxation time study at two field strengths. J Antibiot (Tokyo) (1984) 0.75

Genetic therapy of human neoplastic disease. J Hematother (1993) 0.75

Device-dependent activity estimation and decay correction of radionuclide mixtures with application to Tc-94m PET studies. Med Phys (2001) 0.75

The inhibition of bacterial beta-lactamases by some monocyclic beta-lactams. J Antibiot (Tokyo) (1982) 0.75

Nearest-neighbor and next-nearest-neighbor effects in the proton NMR spectra of the oligoribonucleotides ApGpX and CpApX. Biopolymers (1980) 0.75

Combination chemotherapy and radiation therapy. The medical management of epidural spinal cord compression from testicular cancer. Arch Intern Med (1986) 0.75

On-line liquid chromatography coupled with high field NMR and mass spectrometry (LC-NMR-MS): a new technique for drug metabolite structure elucidation. J Pharm Biomed Anal (1997) 0.75

Individualizing health education in the TVA. Health Educ (1976) 0.75

Activation of class I HLA expression by TNF-alpha and gamma-interferon is mediated through protein kinase C-dependent pathway in CML cell lines. Br J Haematol (1991) 0.75

Molecular approaches to purging of chronic myelogenous leukemia marrow in autologous transplantation. Prog Clin Biol Res (1992) 0.75

Isothiourea derivatives of 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole with broad-spectrum anthelmintic activity. J Med Chem (1987) 0.75

Current studies on hydatid disease in Utah. Proc Annu Meet U S Anim Health Assoc (1974) 0.75

The content of tumor DNA as an indicator of prognosis in patients with T1N0M0 and T2N0M0 carcinoma of the breast. Surgery (1989) 0.75

T-cell-depleted autologous marrow fails to prevent acute graft-versus-host disease after allogeneic marrow transplantation for lymphoblastic lymphoma. Transplant Proc (1992) 0.75

Epsiprantel, a new tapeworm remedy. Preliminary efficacy studies in dogs and cats. Br Vet J (1989) 0.75

In vitro and in vivo efficacy of epsiprantel against Echinococcus granulosus. Res Vet Sci (1991) 0.75

Biofeedback control of migraine: a pilot study. Br J Soc Clin Psychol (1976) 0.75

The degradation of temocillin, a 6 alpha-methoxypenicillin, and identification of the major degradation products. J Pharm Pharmacol (1986) 0.75

Molecular approaches to the diagnosis and treatment of cancer. Stem Cells (1993) 0.75

Geology of the Central Portion of the Queen Maud Range, Transantarctic Mountains. Science (1965) 0.75

Structural elucidation of a novel erythromycin, 13-cyclopentyl-13-desethyl-erythromycin B, from a recombinant Saccharopolyspora erythraea strain, NRRL 2338 pIG/1. J Antibiot (Tokyo) (1999) 0.75

Phase I study of immunotherapy of hepatic metastases of colorectal carcinoma by direct gene transfer. Hum Gene Ther (1994) 0.75