Published in Mol Syst Biol on July 13, 2010
KaiC intersubunit communication facilitates robustness of circadian rhythms in cyanobacteria. Nat Commun (2013) 1.52
The cyanobacterial circadian system: from biophysics to bioevolution. Annu Rev Biophys (2011) 1.39
Flexibility of the C-terminal, or CII, ring of KaiC governs the rhythm of the circadian clock of cyanobacteria. Proc Natl Acad Sci U S A (2011) 1.14
Network balance via CRY signalling controls the Arabidopsis circadian clock over ambient temperatures. Mol Syst Biol (2013) 1.07
Combined SAXS/EM based models of the S. elongatus post-translational circadian oscillator and its interactions with the output His-kinase SasA. PLoS One (2011) 1.05
CryoEM and molecular dynamics of the circadian KaiB-KaiC complex indicates that KaiB monomers interact with KaiC and block ATP binding clefts. J Mol Biol (2013) 1.00
Insight into cyanobacterial circadian timing from structural details of the KaiB-KaiC interaction. Proc Natl Acad Sci U S A (2014) 0.97
Metabolic compensation and circadian resilience in prokaryotic cyanobacteria. Annu Rev Biochem (2014) 0.89
Daily rhythms in the cyanobacterium synechococcus elongatus probed by high-resolution mass spectrometry-based proteomics reveals a small defined set of cyclic proteins. Mol Cell Proteomics (2014) 0.88
Generic temperature compensation of biological clocks by autonomous regulation of catalyst concentration. Proc Natl Acad Sci U S A (2012) 0.88
Nature of KaiB-KaiC binding in the cyanobacterial circadian oscillator. Cell Cycle (2013) 0.87
Loop-loop interactions regulate KaiA-stimulated KaiC phosphorylation in the cyanobacterial KaiABC circadian clock. Biochemistry (2013) 0.84
Mixtures of opposing phosphorylations within hexamers precisely time feedback in the cyanobacterial circadian clock. Proc Natl Acad Sci U S A (2014) 0.83
Quantifying the rhythm of KaiB-C interaction for in vitro cyanobacterial circadian clock. PLoS One (2012) 0.81
Intricate protein-protein interactions in the cyanobacterial circadian clock. J Biol Chem (2014) 0.80
Revealing a two-loop transcriptional feedback mechanism in the cyanobacterial circadian clock. PLoS Comput Biol (2013) 0.79
Discrete gene replication events drive coupling between the cell cycle and circadian clocks. Proc Natl Acad Sci U S A (2016) 0.79
An arginine tetrad as mediator of input-dependent and input-independent ATPases in the clock protein KaiC. Acta Crystallogr D Biol Crystallogr (2014) 0.77
Crystal Structure of the CTP1L Endolysin Reveals How Its Activity Is Regulated by a Secondary Translation Product. J Biol Chem (2015) 0.76
Architecture and mechanism of the central gear in an ancient molecular timer. J R Soc Interface (2017) 0.75
Toward Multiscale Models of Cyanobacterial Growth: A Modular Approach. Front Bioeng Biotechnol (2016) 0.75
A thermodynamically consistent model of the post-translational Kai circadian clock. PLoS Comput Biol (2017) 0.75
Protein measurement with the Folin phenol reagent. J Biol Chem (1951) 1743.91
Expression of a gene cluster kaiABC as a circadian feedback process in cyanobacteria. Science (1998) 7.38
Reconstitution of circadian oscillation of cyanobacterial KaiC phosphorylation in vitro. Science (2005) 7.28
Design principles of biochemical oscillators. Nat Rev Mol Cell Biol (2008) 4.55
No transcription-translation feedback in circadian rhythm of KaiC phosphorylation. Science (2004) 4.47
KaiA-stimulated KaiC phosphorylation in circadian timing loops in cyanobacteria. Proc Natl Acad Sci U S A (2002) 4.10
Resilient circadian oscillator revealed in individual cyanobacteria. Nature (2004) 3.84
Ordered phosphorylation governs oscillation of a three-protein circadian clock. Science (2007) 3.78
Cyanobacterial circadian clockwork: roles of KaiA, KaiB and the kaiBC promoter in regulating KaiC. EMBO J (2003) 3.47
ON THE MECHANISM OF TEMPERATURE INDEPENDENCE IN A BIOLOGICAL CLOCK. Proc Natl Acad Sci U S A (1957) 3.22
Nucleotide binding and autophosphorylation of the clock protein KaiC as a circadian timing process of cyanobacteria. Proc Natl Acad Sci U S A (2000) 3.17
Native mass spectrometry: a bridge between interactomics and structural biology. Nat Methods (2008) 3.11
Role of KaiC phosphorylation in the circadian clock system of Synechococcus elongatus PCC 7942. Proc Natl Acad Sci U S A (2004) 3.03
A sequential program of dual phosphorylation of KaiC as a basis for circadian rhythm in cyanobacteria. EMBO J (2007) 2.83
Cyanobacterial circadian pacemaker: Kai protein complex dynamics in the KaiC phosphorylation cycle in vitro. Mol Cell (2006) 2.56
Circadian clock protein KaiC forms ATP-dependent hexameric rings and binds DNA. Proc Natl Acad Sci U S A (2002) 2.50
Identification of key phosphorylation sites in the circadian clock protein KaiC by crystallographic and mutagenetic analyses. Proc Natl Acad Sci U S A (2004) 2.43
Elucidating the ticking of an in vitro circadian clockwork. PLoS Biol (2007) 2.19
Crystal structure of the C-terminal clock-oscillator domain of the cyanobacterial KaiA protein. Nat Struct Mol Biol (2004) 2.08
Improving the performance of a quadrupole time-of-flight instrument for macromolecular mass spectrometry. Anal Chem (2006) 2.06
Dual KaiC-based oscillations constitute the circadian system of cyanobacteria. Genes Dev (2008) 1.95
Crystal structure of circadian clock protein KaiA from Synechococcus elongatus. J Biol Chem (2004) 1.73
Autonomous synchronization of the circadian KaiC phosphorylation rhythm. Nat Struct Mol Biol (2007) 1.54
An allosteric model of circadian KaiC phosphorylation. Proc Natl Acad Sci U S A (2007) 1.53
Functioning and robustness of a bacterial circadian clock. Mol Syst Biol (2007) 1.46
Hourglass model for a protein-based circadian oscillator. Phys Rev Lett (2006) 1.43
Circadian rhythmicity by autocatalysis. PLoS Comput Biol (2006) 1.32
Unraveling the molecular basis of subunit specificity in P pilus assembly by mass spectrometry. Proc Natl Acad Sci U S A (2008) 1.14
Monomer-shuffling and allosteric transition in KaiC circadian oscillation. PLoS One (2007) 1.14
Nonparametric entrainment of the in vitro circadian phosphorylation rhythm of cyanobacterial KaiC by temperature cycle. Proc Natl Acad Sci U S A (2009) 1.12
The minimum information about a proteomics experiment (MIAPE). Nat Biotechnol (2007) 10.24
Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling. Nature (2011) 6.09
Structural basis for CRISPR RNA-guided DNA recognition by Cascade. Nat Struct Mol Biol (2011) 6.02
Multiplex peptide stable isotope dimethyl labeling for quantitative proteomics. Nat Protoc (2009) 4.61
RNA-guided complex from a bacterial immune system enhances target recognition through seed sequence interactions. Proc Natl Acad Sci U S A (2011) 4.58
The CRAPome: a contaminant repository for affinity purification-mass spectrometry data. Nat Methods (2013) 4.34
Selective isolation at the femtomole level of phosphopeptides from proteolytic digests using 2D-NanoLC-ESI-MS/MS and titanium oxide precolumns. Anal Chem (2004) 4.06
Recommendations from the 2008 International Summit on Proteomics Data Release and Sharing Policy: the Amsterdam principles. J Proteome Res (2009) 3.77
The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markers. EMBO J (2012) 3.70
Genome sequence of the cyanobacterium Prochlorococcus marinus SS120, a nearly minimal oxyphototrophic genome. Proc Natl Acad Sci U S A (2003) 3.55
A high-quality catalog of the Drosophila melanogaster proteome. Nat Biotechnol (2007) 3.34
Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis. Mol Cell Proteomics (2007) 3.33
Phosphorylation dynamics during early differentiation of human embryonic stem cells. Cell Stem Cell (2009) 3.03
Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complex. Cell (2012) 3.03
Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors. Nature (2012) 2.76
The generating function of CID, ETD, and CID/ETD pairs of tandem mass spectra: applications to database search. Mol Cell Proteomics (2010) 2.64
Regulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7. J Cell Biol (2008) 2.56
GATA-1 forms distinct activating and repressive complexes in erythroid cells. EMBO J (2005) 2.56
MSQuant, an open source platform for mass spectrometry-based quantitative proteomics. J Proteome Res (2010) 2.40
Sequential waves of functionally related proteins are expressed when B cells prepare for antibody secretion. Immunity (2003) 2.40
Next-generation proteomics: towards an integrative view of proteome dynamics. Nat Rev Genet (2012) 2.39
Metabolic labeling of C. elegans and D. melanogaster for quantitative proteomics. Nat Biotechnol (2003) 2.37
The fluxes through glycolytic enzymes in Saccharomyces cerevisiae are predominantly regulated at posttranscriptional levels. Proc Natl Acad Sci U S A (2007) 2.36
Genome-wide expression dynamics of a marine virus and host reveal features of co-evolution. Nature (2007) 2.27
Lipid II is an intrinsic component of the pore induced by nisin in bacterial membranes. J Biol Chem (2003) 2.26
GMP synthetase stimulates histone H2B deubiquitylation by the epigenetic silencer USP7. Mol Cell (2005) 2.21
Differential targeting of two distinct SWI/SNF-related Drosophila chromatin-remodeling complexes. Mol Cell Biol (2004) 2.18
Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. Anal Chem (2009) 2.10
The PRoteomics IDEntification (PRIDE) Converter 2 framework: an improved suite of tools to facilitate data submission to the PRIDE database and the ProteomeXchange consortium. Mol Cell Proteomics (2012) 2.10
Improving the performance of a quadrupole time-of-flight instrument for macromolecular mass spectrometry. Anal Chem (2006) 2.06
Phosphopeptide fragmentation and analysis by mass spectrometry. J Mass Spectrom (2009) 2.04
A quest for human and mouse embryonic stem cell-specific proteins. Mol Cell Proteomics (2006) 2.04
Mass spectrometry-based proteomics and network biology. Annu Rev Biochem (2012) 2.02
An internal antisense RNA regulates expression of the photosynthesis gene isiA. Proc Natl Acad Sci U S A (2006) 1.95
A large synthetic peptide and phosphopeptide reference library for mass spectrometry-based proteomics. Nat Biotechnol (2013) 1.93
Improved peptide identification by targeted fragmentation using CID, HCD and ETD on an LTQ-Orbitrap Velos. J Proteome Res (2011) 1.93
Severe acute respiratory syndrome coronavirus (SARS-CoV) infection inhibition using spike protein heptad repeat-derived peptides. Proc Natl Acad Sci U S A (2004) 1.89
Munc13-4 is an effector of rab27a and controls secretion of lysosomes in hematopoietic cells. Mol Biol Cell (2004) 1.85
A central role for TFIID in the pluripotent transcription circuitry. Nature (2013) 1.82
The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/β-catenin coactivators essential for intestinal homeostasis. PLoS Biol (2010) 1.81
Donor-strand exchange in chaperone-assisted pilus assembly proceeds through a concerted beta strand displacement mechanism. Mol Cell (2006) 1.81
Highly robust, automated, and sensitive online TiO2-based phosphoproteomics applied to study endogenous phosphorylation in Drosophila melanogaster. J Proteome Res (2007) 1.80
Monitoring macromolecular complexes involved in the chaperonin-assisted protein folding cycle by mass spectrometry. Nat Methods (2005) 1.79
Ion mobility mass spectrometry of proteins and protein assemblies. Chem Soc Rev (2009) 1.77
Activation of FoxM1 during G2 requires cyclin A/Cdk-dependent relief of autorepression by the FoxM1 N-terminal domain. Mol Cell Biol (2008) 1.67
High-sensitivity Orbitrap mass analysis of intact macromolecular assemblies. Nat Methods (2012) 1.67
High-resolution mass spectrometry of viral assemblies: molecular composition and stability of dimorphic hepatitis B virus capsids. Proc Natl Acad Sci U S A (2008) 1.64
Native protein mass spectrometry: from intact oligomers to functional machineries. Curr Opin Chem Biol (2004) 1.61
Human Ccr4-Not complexes contain variable deadenylase subunits. Biochem J (2009) 1.61
An experimental correction for arginine-to-proline conversion artifacts in SILAC-based quantitative proteomics. Nat Methods (2007) 1.59
Dis3-like 1: a novel exoribonuclease associated with the human exosome. EMBO J (2010) 1.57
Triplex protein quantification based on stable isotope labeling by peptide dimethylation applied to cell and tissue lysates. Proteomics (2008) 1.54
Complement is activated by IgG hexamers assembled at the cell surface. Science (2014) 1.52
Interrogating viral capsid assembly with ion mobility-mass spectrometry. Nat Chem (2010) 1.47
Proteome analysis of yeast response to various nutrient limitations. Mol Syst Biol (2006) 1.47
Functioning and robustness of a bacterial circadian clock. Mol Syst Biol (2007) 1.46
Straightforward ladder sequencing of peptides using a Lys-N metalloendopeptidase. Nat Methods (2008) 1.46
The quantitative proteomes of human-induced pluripotent stem cells and embryonic stem cells. Mol Syst Biol (2011) 1.44
Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium. Mol Syst Biol (2012) 1.44
Quantitative proteomics by metabolic labeling of model organisms. Mol Cell Proteomics (2009) 1.42
Structure of the yeast vacuolar ATPase. J Biol Chem (2008) 1.41
Comprehensive analysis of the secreted proteins of the parasite Haemonchus contortus reveals extensive sequence variation and differential immune recognition. J Biol Chem (2003) 1.41
Native tandem and ion mobility mass spectrometry highlight structural and modular similarities in clustered-regularly-interspaced shot-palindromic-repeats (CRISPR)-associated protein complexes from Escherichia coli and Pseudomonas aeruginosa. Mol Cell Proteomics (2012) 1.40
RNA polymerase I contains a TFIIF-related DNA-binding subcomplex. Mol Cell (2010) 1.40
Cooperative action of NC2 and Mot1p to regulate TATA-binding protein function across the genome. Genes Dev (2008) 1.38
Toward a comprehensive characterization of a human cancer cell phosphoproteome. J Proteome Res (2012) 1.37
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis. Immunol Cell Biol (2010) 1.37
Quantifying origins of cell-to-cell variations in gene expression. Biophys J (2008) 1.36
Species-specific determinants in the IgG CH3 domain enable Fab-arm exchange by affecting the noncovalent CH3-CH3 interaction strength. J Immunol (2011) 1.34
Chaperonin complexes monitored by ion mobility mass spectrometry. J Am Chem Soc (2009) 1.33
Toward full peptide sequence coverage by dual fragmentation combining electron-transfer and higher-energy collision dissociation tandem mass spectrometry. Anal Chem (2012) 1.32
On terminal alkynes that can react with active-site cysteine nucleophiles in proteases. J Am Chem Soc (2013) 1.32
The diversity of cyanobacterial metabolism: genome analysis of multiple phototrophic microorganisms. BMC Genomics (2012) 1.32
Large-scale quantitative assessment of different in-solution protein digestion protocols reveals superior cleavage efficiency of tandem Lys-C/trypsin proteolysis over trypsin digestion. J Proteome Res (2012) 1.32
The phosphoproteomics data explosion. Curr Opin Chem Biol (2009) 1.30
Role of translational coupling in robustness of bacterial chemotaxis pathway. PLoS Biol (2009) 1.28
Targeted analysis of protein termini. J Proteome Res (2007) 1.28
Profiling of N-acetylated protein termini provides in-depth insights into the N-terminal nature of the proteome. Mol Cell Proteomics (2010) 1.28
Determination of stoichiometry and conformational changes in the first step of the P22 tail assembly. J Mol Biol (2008) 1.27
In-depth qualitative and quantitative profiling of tyrosine phosphorylation using a combination of phosphopeptide immunoaffinity purification and stable isotope dimethyl labeling. Mol Cell Proteomics (2009) 1.27
cGMP-binding prepares PKG for substrate binding by disclosing the C-terminal domain. J Mol Biol (2007) 1.27
Stoichiometry of the peripheral stalk subunits E and G of yeast V1-ATPase determined by mass spectrometry. J Biol Chem (2007) 1.26
Norwalk virus assembly and stability monitored by mass spectrometry. Mol Cell Proteomics (2010) 1.26
Endogenous phosphatidylcholine and a long spacer ligand stabilize the lipid-binding groove of CD1b. EMBO J (2006) 1.26
Small RNAs establish delays and temporal thresholds in gene expression. Biophys J (2008) 1.24
Differential oxidation of protein-tyrosine phosphatases. J Biol Chem (2004) 1.24
Thermal robustness of signaling in bacterial chemotaxis. Cell (2011) 1.23
Mass spectrometric analysis of the Schistosoma mansoni tegumental sub-proteome. J Proteome Res (2005) 1.23
Coupled activation and degradation of eEF2K regulates protein synthesis in response to genotoxic stress. Sci Signal (2012) 1.23
Tandem mass spectrometry of intact GroEL-substrate complexes reveals substrate-specific conformational changes in the trans ring. J Am Chem Soc (2006) 1.22
Plasma membrane proteomics of human embryonic stem cells and human embryonal carcinoma cells. J Proteome Res (2008) 1.22
Proteome-wide protein concentrations in the human heart. Mol Biosyst (2010) 1.21
Stability and shape of hepatitis B virus capsids in vacuo. Angew Chem Int Ed Engl (2008) 1.20
High precision platelet releasate definition by quantitative reversed protein profiling--brief report. Arterioscler Thromb Vasc Biol (2013) 1.20
Structural biology of RNA polymerase III: mass spectrometry elucidates subcomplex architecture. Structure (2007) 1.19
Structural studies on flavin reductase PheA2 reveal binding of NAD in an unusual folded conformation and support novel mechanism of action. J Biol Chem (2003) 1.18
Neuron specific Rab4 effector GRASP-1 coordinates membrane specialization and maturation of recycling endosomes. PLoS Biol (2010) 1.18
Experimental and computational analysis of transcriptional start sites in the cyanobacterium Prochlorococcus MED4. Nucleic Acids Res (2003) 1.18