Dopamine D1 receptors, regulation of gene expression in the brain, and neurodegeneration.

PubWeight™: 0.98‹?› | Rank: Top 15%

🔗 View Article (PMC 3803153)

Published in CNS Neurol Disord Drug Targets on November 01, 2010

Authors

Jean Lud Cadet1, Subramaniam Jayanthi, Michael T McCoy, Genevieve Beauvais, Ning Sheng Cai

Author Affiliations

1: Molecular Neuropsychiatry Research Branch, DHHS/NIH/NIDA Intramural Research Program, Baltimore, MD 21224, USA. jcadet@intra.nida.nih.gov

Articles citing this

CREB phosphorylation regulates striatal transcriptional responses in the self-administration model of methamphetamine addiction in the rat. Neurobiol Dis (2013) 1.10

Chronic methamphetamine exposure suppresses the striatal expression of members of multiple families of immediate early genes (IEGs) in the rat: normalization by an acute methamphetamine injection. Psychopharmacology (Berl) (2011) 1.06

Methamphetamine causes differential alterations in gene expression and patterns of histone acetylation/hypoacetylation in the rat nucleus accumbens. PLoS One (2012) 1.06

Methamphetamine downregulates striatal glutamate receptors via diverse epigenetic mechanisms. Biol Psychiatry (2013) 1.04

Involvement of dopamine receptors in binge methamphetamine-induced activation of endoplasmic reticulum and mitochondrial stress pathways. PLoS One (2011) 0.96

Stimulation of the D5 dopamine receptor acidifies the lysosomal pH of retinal pigmented epithelial cells and decreases accumulation of autofluorescent photoreceptor debris. J Neurochem (2012) 0.96

Transcriptional and epigenetic substrates of methamphetamine addiction and withdrawal: evidence from a long-access self-administration model in the rat. Mol Neurobiol (2014) 0.89

Chronic methamphetamine abuse and corticostriatal deficits revealed by neuroimaging. Brain Res (2014) 0.87

Dopamine Receptors and Neurodegeneration. Aging Dis (2015) 0.83

Dopamine signaling promotes the xenobiotic stress response and protein homeostasis. EMBO J (2016) 0.82

Genome-wide profiling identifies a subset of methamphetamine (METH)-induced genes associated with METH-induced increased H4K5Ac binding in the rat striatum. BMC Genomics (2013) 0.82

DRD2 and DRD4 genes related to cognitive deficits in HIV-infected adults who abuse alcohol. Behav Brain Funct (2015) 0.78

Methamphetamine addiction: involvement of CREB and neuroinflammatory signaling pathways. Psychopharmacology (Berl) (2016) 0.78

Enhanced upregulation of CRH mRNA expression in the nucleus accumbens of male rats after a second injection of methamphetamine given thirty days later. PLoS One (2014) 0.77

Differential effects of binge methamphetamine injections on the mRNA expression of histone deacetylases (HDACs) in the rat striatum. Neurotoxicology (2014) 0.77

Increased expression of proenkephalin and prodynorphin mRNAs in the nucleus accumbens of compulsive methamphetamine taking rats. Sci Rep (2016) 0.75

CAMKII-conditional deletion of histone deacetylase 2 potentiates acute methamphetamine-induced expression of immediate early genes in the mouse nucleus accumbens. Sci Rep (2015) 0.75

Dopamine helps worms deal with stress. EMBO J (2016) 0.75

Pridopidine activates neuroprotective pathways impaired in Huntington Disease. Hum Mol Genet (2016) 0.75

A Dopamine Receptor genetic variant enhances perceptual speed in cognitive healthy subjects. Alzheimers Dement (N Y) (2017) 0.75

Articles cited by this

(truncated to the top 100)

AP-1 as a regulator of cell life and death. Nat Cell Biol (2002) 10.10

Dopamine receptors: from structure to function. Physiol Rev (1998) 8.90

Cocaine receptors on dopamine transporters are related to self-administration of cocaine. Science (1987) 6.58

Structural plasticity associated with exposure to drugs of abuse. Neuropharmacology (2004) 6.08

Dopamine neuron systems in the brain: an update. Trends Neurosci (2007) 4.44

The basal ganglia and adaptive motor control. Science (1994) 4.27

Dopamine-sensitive adenylate cyclase in caudate nucleus of rat brain, and its similarity to the "dopamine receptor". Proc Natl Acad Sci U S A (1972) 4.03

Anatomical and physiological plasticity of dendritic spines. Annu Rev Neurosci (2007) 3.75

Opposing patterns of signaling activation in dopamine D1 and D2 receptor-expressing striatal neurons in response to cocaine and haloperidol. J Neurosci (2008) 3.50

Golf: an olfactory neuron specific-G protein involved in odorant signal transduction. Science (1989) 3.33

The basal ganglia: learning new tricks and loving it. Curr Opin Neurobiol (2005) 3.28

Mice deficient in G(olf) are anosmic. Neuron (1998) 3.00

Inducibility and negative autoregulation of CREM: an alternative promoter directs the expression of ICER, an early response repressor. Cell (1993) 2.84

Neurotransmitters and neuromodulators in the basal ganglia. Trends Neurosci (1990) 2.83

Methamphetamine toxicity and messengers of death. Brain Res Rev (2009) 2.69

Inositol trisphosphate and calcium signalling mechanisms. Biochim Biophys Acta (2008) 2.66

NAB2, a corepressor of NGFI-A (Egr-1) and Krox20, is induced by proliferative and differentiative stimuli. Mol Cell Biol (1996) 2.51

D1-D2 dopamine receptor heterooligomers with unique pharmacology are coupled to rapid activation of Gq/11 in the striatum. Proc Natl Acad Sci U S A (2006) 2.48

Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1. Nature (1991) 2.41

Oxidative pathways for catecholamines in the genesis of neuromelanin and cytotoxic quinones. Mol Pharmacol (1978) 2.37

Dopamine D1 and D2 receptor Co-activation generates a novel phospholipase C-mediated calcium signal. J Biol Chem (2004) 2.32

Roles for nigrostriatal--not just mesocorticolimbic--dopamine in reward and addiction. Trends Neurosci (2009) 2.09

Targeting the dopamine D1 receptor in schizophrenia: insights for cognitive dysfunction. Psychopharmacology (Berl) (2004) 2.06

Electron microscopic analysis of D1 and D2 dopamine receptor proteins in the dorsal striatum and their synaptic relationships with motor corticostriatal afferents. J Neurosci (1995) 1.91

The neurobiology of cocaine addiction. Sci Pract Perspect (2005) 1.90

Molecular diversity of the dopamine receptors. Annu Rev Pharmacol Toxicol (1993) 1.89

Molecular cloning and expression of a D1 dopamine receptor linked to adenylyl cyclase activation. Proc Natl Acad Sci U S A (1990) 1.87

Cocaine-induced intracellular signaling and gene expression are oppositely regulated by the dopamine D1 and D3 receptors. J Neurosci (2004) 1.80

Autoxidation versus covalent binding of quinones as the mechanism of toxicity of dopamine, 6-hydroxydopamine, and related compounds toward C1300 neuroblastoma cells in vitro. Mol Pharmacol (1978) 1.79

Quantitative autoradiographic localization of the D1 and D2 subtypes of dopamine receptors in rat brain. J Neurosci (1986) 1.76

Molecular cloning and expression of the gene for a human D1 dopamine receptor. Nature (1990) 1.75

G(olf) and Gs in rat basal ganglia: possible involvement of G(olf) in the coupling of dopamine D1 receptor with adenylyl cyclase. J Neurosci (1993) 1.66

Calcineurin: a central controller of signalling in eukaryotes. EMBO Rep (2004) 1.65

Dopamine-sensitive adenyl cyclase: possible role in synaptic transmission. Science (1971) 1.65

Dopamine-sensitive adenylate cyclase in mammalian brain: a possible site of action of antipsychotic drugs. Proc Natl Acad Sci U S A (1974) 1.63

Amphetamine regulates gene expression in rat striatum via transcription factor CREB. J Neurosci (1994) 1.61

Regional, cellular, and subcellular variations in the distribution of D1 and D5 dopamine receptors in primate brain. J Neurosci (1995) 1.61

Free radicals and the pathobiology of brain dopamine systems. Neurochem Int (1998) 1.60

Calcineurin/NFAT-induced up-regulation of the Fas ligand/Fas death pathway is involved in methamphetamine-induced neuronal apoptosis. Proc Natl Acad Sci U S A (2005) 1.59

Egr transcription factors in the nervous system. Neurochem Int (1997) 1.56

c-Fos facilitates the acquisition and extinction of cocaine-induced persistent changes. J Neurosci (2006) 1.55

Attention-deficit-hyperactivity disorder: an update. Pharmacotherapy (2009) 1.53

Dopamine receptor genes: new tools for molecular psychiatry. J Psychiatry Neurosci (1992) 1.53

A complex program of striatal gene expression induced by dopaminergic stimulation. J Neurosci (1998) 1.47

SKF83959 selectively regulates phosphatidylinositol-linked D1 dopamine receptors in rat brain. J Neurochem (2003) 1.46

NR4A1, 2, 3--an orphan nuclear hormone receptor family involved in cell apoptosis and carcinogenesis. Histol Histopathol (2006) 1.43

Methamphetamine induces neuronal apoptosis via cross-talks between endoplasmic reticulum and mitochondria-dependent death cascades. FASEB J (2004) 1.39

Relationship of neuroleptic drug effects at brain dopamine, serotonin, alpha-adrenergic, and histamine receptors to clinical potency. Am J Psychiatry (1980) 1.38

Egr-1 induces the expression of its corepressor nab2 by activation of the nab2 promoter thereby establishing a negative feedback loop. J Biol Chem (2005) 1.38

Dopamine receptors--physiological understanding to therapeutic intervention potential. Pharmacol Ther (1999) 1.38

Localization of D1 dopamine receptor mRNA in brain supports a role in cognitive, affective, and neuroendocrine aspects of dopaminergic neurotransmission. Proc Natl Acad Sci U S A (1991) 1.38

Stimulation of a dopamine D1 receptor enhances inositol phosphates formation in rat brain. J Pharmacol Exp Ther (1990) 1.37

Induction of inducible cAMP early repressor expression in nucleus accumbens by stress or amphetamine increases behavioral responses to emotional stimuli. J Neurosci (2006) 1.35

The dopamine D1 receptor is a critical mediator for cocaine-induced gene expression. J Neurochem (2002) 1.34

AP-1 proteins in the adult brain: facts and fiction about effectors of neuroprotection and neurodegeneration. Oncogene (2001) 1.31

The neurochemical circuitry of schizophrenia. Pharmacopsychiatry (2006) 1.31

A comprehensive analysis of the distribution of FGF-2 and FGFR1 in the rat brain. Brain Res (1995) 1.30

NFAT signaling in neural development and axon growth. Int J Dev Neurosci (2007) 1.30

High level calcineurin activity predisposes neuronal cells to apoptosis. J Biol Chem (1999) 1.28

Expression of striatal D1 dopamine receptors coupled to inositol phosphate production and Ca2+ mobilization in Xenopus oocytes. Proc Natl Acad Sci U S A (1990) 1.27

Differential loss of striatal projection systems in Huntington's disease: a quantitative immunohistochemical study. J Chem Neuroanat (2004) 1.27

Subdivisions of the dopamine-containing A8-A9-A10 complex identified by their differential mesostriatal innervation of striosomes and extrastriosomal matrix. Neuroscience (1987) 1.27

Striatal D1 and D2 dopamine receptor loss in asymptomatic mutation carriers of Huntington's disease. Ann Neurol (1996) 1.23

Methamphetamine-induced cell death: selective vulnerability in neuronal subpopulations of the striatum in mice. Neuroscience (2006) 1.23

Inhibition of the dopamine D1 receptor signaling by PSD-95. J Biol Chem (2007) 1.21

Autoradiographic localization of D1 dopamine receptors in the rat brain with [3H]SCH 23390. Brain Res (1986) 1.21

Norepinephrine and dopamine as learning signals. Neural Plast (2004) 1.20

Dopaminergic neurons. Int J Biochem Cell Biol (2004) 1.19

The history of dopamine and levodopa in the treatment of Parkinson's disease. Mov Disord (2008) 1.19

Dopamine receptor-mediated Ca(2+) signaling in striatal medium spiny neurons. J Biol Chem (2004) 1.18

Dopamine D1 and D2 receptor gene expression in the striatum in Huntington's disease. Ann Neurol (1997) 1.18

Methamphetamine causes differential regulation of pro-death and anti-death Bcl-2 genes in the mouse neocortex. FASEB J (2001) 1.17

Dopamine induces apoptosis through an oxidation-involved SAPK/JNK activation pathway. J Biol Chem (1998) 1.17

Evidence for the coupling of Gq protein to D1-like dopamine sites in rat striatum: possible role in dopamine-mediated inositol phosphate formation. Mol Pharmacol (1995) 1.16

Dynamic regulation of NGFI-A (zif268, egr1) gene expression in the striatum. J Neurosci (1992) 1.15

G(olf)alpha mediates dopamine D1 receptor signaling. J Neurosci (2000) 1.12

The role of neurotensin in central nervous system pathophysiology: what is the evidence? J Psychiatry Neurosci (2006) 1.10

Making a neuron: Cdk5 in embryonic and adult neurogenesis. Trends Neurosci (2009) 1.08

Identification of differentially regulated transcripts in mouse striatum following methamphetamine treatment--an oligonucleotide microarray approach. J Neurochem (2004) 1.07

Methamphetamine induces dopamine D1 receptor-dependent endoplasmic reticulum stress-related molecular events in the rat striatum. PLoS One (2009) 1.06

Neurotensin: role in psychiatric and neurological diseases. Peptides (2006) 1.05

Dopamine D1 receptor activation induces tau phosphorylation via cdk5 and GSK3 signaling pathways. Neuropharmacology (2009) 1.05

Dopamine-induced apoptosis is mediated by oxidative stress and Is enhanced by cyanide in differentiated PC12 cells. J Neurochem (2000) 1.04

Toxicity of dopamine to striatal neurons in vitro and potentiation of cell death by a mitochondrial inhibitor. J Neurochem (1998) 1.04

Methamphetamine- and trauma-induced brain injuries: comparative cellular and molecular neurobiological substrates. Biol Psychiatry (2009) 1.04

Differential effects of D1 and D2 dopamine receptor antagonists on acute amphetamine- or methamphetamine-induced up-regulation of zif/268 mRNA expression in rat forebrain. J Neurochem (1995) 1.04

Stimulated D(1) dopamine receptors couple to multiple Galpha proteins in different brain regions. J Neurochem (2001) 1.04

Activation of transcription factor genes in striatum by cocaine: role of both serotonin and dopamine systems. J Pharmacol Exp Ther (1993) 1.04

Dopamine and glutamate agonists stimulate neuron-specific expression of Fos-like protein in the striatum. J Neurophysiol (1992) 1.03

Amphetamine-induced dopamine release in the rat striatum: an in vivo microdialysis study. J Neurochem (1988) 1.03

Cocaine: an in vivo microdialysis evaluation of its acute action on dopamine transmission in rat striatum. Synapse (1989) 1.03

Comparison of the distribution of D-1 and D-2 dopamine receptors in the rat brain. J Chem Neuroanat (1989) 1.03

Molecular aspects of neuropeptide regulation and function in the corpus striatum and nucleus accumbens. Brain Res Brain Res Rev (1994) 1.03

A single injection of amphetamine or methamphetamine induces dynamic alterations in c-fos, zif/268 and preprodynorphin messenger RNA expression in rat forebrain. Neuroscience (1995) 1.02

Dopamine regulates brain-derived neurotrophic factor (BDNF) expression in cultured embryonic mouse striatal cells. Neuroreport (2001) 1.00

Topographic organization of ascending dopaminergic projections. Ann N Y Acad Sci (1988) 1.00

D1 dopamine receptor mediates dopamine-induced cytotoxicity via the ERK signal cascade. J Biol Chem (2004) 0.98

Neuropeptide Y protects against methamphetamine-induced neuronal apoptosis in the mouse striatum. J Neurosci (2005) 0.98

Basic research on dopamine in Parkinson's disease and the discovery of the nigrostriatal dopamine pathway: the view of an eyewitness. Neurodegener Dis (2008) 0.98

Methamphetamine causes coordinate regulation of Src, Cas, Crk, and the Jun N-terminal kinase-Jun pathway. Mol Pharmacol (2002) 0.97

Articles by these authors

Neurotoxicity of substituted amphetamines: molecular and cellular mechanisms. Neurotox Res (2007) 1.77

Speed kills: cellular and molecular bases of methamphetamine-induced nerve terminal degeneration and neuronal apoptosis. FASEB J (2003) 1.68

Calcineurin/NFAT-induced up-regulation of the Fas ligand/Fas death pathway is involved in methamphetamine-induced neuronal apoptosis. Proc Natl Acad Sci U S A (2005) 1.59

Methamphetamine self-administration is associated with persistent biochemical alterations in striatal and cortical dopaminergic terminals in the rat. PLoS One (2010) 1.22

Methamphetamine-induced neuronal apoptosis involves the activation of multiple death pathways. Review. Neurotox Res (2005) 1.14

CREB phosphorylation regulates striatal transcriptional responses in the self-administration model of methamphetamine addiction in the rat. Neurobiol Dis (2013) 1.10

Chronic methamphetamine exposure suppresses the striatal expression of members of multiple families of immediate early genes (IEGs) in the rat: normalization by an acute methamphetamine injection. Psychopharmacology (Berl) (2011) 1.06

Methamphetamine causes differential alterations in gene expression and patterns of histone acetylation/hypoacetylation in the rat nucleus accumbens. PLoS One (2012) 1.06

Methamphetamine induces dopamine D1 receptor-dependent endoplasmic reticulum stress-related molecular events in the rat striatum. PLoS One (2009) 1.06

Methamphetamine induces apoptosis in an immortalized rat striatal cell line by activating the mitochondrial cell death pathway. Neuropharmacology (2002) 1.03

Methamphetamine preconditioning alters midbrain transcriptional responses to methamphetamine-induced injury in the rat striatum. PLoS One (2009) 1.02

Methamphetamine administration causes death of dopaminergic neurons in the mouse olfactory bulb. Biol Psychiatry (2006) 1.02

Methamphetamine causes coordinate regulation of Src, Cas, Crk, and the Jun N-terminal kinase-Jun pathway. Mol Pharmacol (2002) 0.97

Methamphetamine preconditioning: differential protective effects on monoaminergic systems in the rat brain. Neurotox Res (2009) 0.97

Involvement of dopamine receptors in binge methamphetamine-induced activation of endoplasmic reticulum and mitochondrial stress pathways. PLoS One (2011) 0.96

Mice with partial deficiency of c-Jun show attenuation of methamphetamine-induced neuronal apoptosis. Mol Pharmacol (2002) 0.93

Differential effects of methamphetamine and SCH23390 on the expression of members of IEG families of transcription factors in the rat striatum. Brain Res (2010) 0.89

Transcriptional and epigenetic substrates of methamphetamine addiction and withdrawal: evidence from a long-access self-administration model in the rat. Mol Neurobiol (2014) 0.89

Analysis of ecstasy (MDMA)-induced transcriptional responses in the rat cortex. FASEB J (2002) 0.87

Methamphetamine preconditioning causes differential changes in striatal transcriptional responses to large doses of the drug. Dose Response (2010) 0.86

Epigenetic landscape of amphetamine and methamphetamine addiction in rodents. Epigenetics (2015) 0.83

Methamphetamine-induced dopamine-independent alterations in striatal gene expression in the 6-hydroxydopamine hemiparkinsonian rats. PLoS One (2010) 0.83

Distinct gene expression signatures in the striata of wild-type and heterozygous c-fos knockout mice following methamphetamine administration: evidence from cDNA array analyses. Synapse (2002) 0.83

High-dose fenfluramine administration decreases serotonin transporter binding, but not serotonin transporter protein levels, in rat forebrain. Synapse (2003) 0.82

Altered gene expression in pulmonary tissue of tryptophan hydroxylase-1 knockout mice: implications for pulmonary arterial hypertension. PLoS One (2011) 0.82

Genome-wide profiling identifies a subset of methamphetamine (METH)-induced genes associated with METH-induced increased H4K5Ac binding in the rat striatum. BMC Genomics (2013) 0.82

Epigenetics of methamphetamine-induced changes in glutamate function. Neuropsychopharmacology (2013) 0.80

Serial analysis of gene expression in the rat striatum following methamphetamine administration. Ann N Y Acad Sci (2006) 0.78

cDNA array analysis of gene expression profiles in the striata of wild-type and Cu/Zn superoxide dismutase transgenic mice treated with neurotoxic doses of amphetamine. FASEB J (2002) 0.76

Substituted amphetamines that produce long-term serotonin depletion in rat brain ("neurotoxicity") do not decrease serotonin transporter protein expression. Ann N Y Acad Sci (2004) 0.76