Published in Stem Cells on September 01, 2010
Translating dosage compensation to trisomy 21. Nature (2013) 1.75
Altered hematopoiesis in trisomy 21 as revealed through in vitro differentiation of isogenic human pluripotent cells. Proc Natl Acad Sci U S A (2012) 1.62
Genetic and epigenetic stability of human pluripotent stem cells. Nat Rev Genet (2012) 1.38
Human pluripotent stem cells: applications and challenges in neurological diseases. Front Physiol (2012) 1.31
Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21. EMBO Mol Med (2013) 1.30
Pluripotent stem cells in disease modelling and drug discovery. Nat Rev Mol Cell Biol (2016) 1.24
Deficits in human trisomy 21 iPSCs and neurons. Proc Natl Acad Sci U S A (2013) 1.07
Genomic analysis of hESC pedigrees identifies de novo mutations and enables determination of the timing and origin of mutational events. Cell Rep (2013) 0.90
Generation of disease-specific induced pluripotent stem cells from patients with different karyotypes of Down syndrome. Stem Cell Res Ther (2012) 0.84
TeratoScore: Assessing the Differentiation Potential of Human Pluripotent Stem Cells by Quantitative Expression Analysis of Teratomas. Stem Cell Reports (2015) 0.83
Constitutional trisomy 8 mosaicism as a model for epigenetic studies of aneuploidy. Epigenetics Chromatin (2013) 0.81
Registration of human embryonic stem cell lines: Korea, 2010. Osong Public Health Res Perspect (2011) 0.80
Gene expression analysis of induced pluripotent stem cells from aneuploid chromosomal syndromes. BMC Genomics (2013) 0.80
Non-coding RNAs in pluripotency and neural differentiation of human pluripotent stem cells. Front Genet (2014) 0.80
Gene expression changes in the MAPK pathway in both Fragile X and Down syndrome human neural progenitor cells. Am J Stem Cells (2012) 0.79
Tumor Budding, Micropapillary Pattern, and Polyploidy Giant Cancer Cells in Colorectal Cancer: Current Status and Future Prospects. Stem Cells Int (2016) 0.77
The Effect of Prolonged Culture of Chromosomally Abnormal Human Embryos on The Rate of Diploid Cells. Int J Fertil Steril (2015) 0.77
Epigenetic changes in the developing brain: Effects on behavior. Proc Natl Acad Sci U S A (2015) 0.76
Analysis of chromosomal aberrations and recombination by allelic bias in RNA-Seq. Nat Commun (2016) 0.75
Molecular Characterization of Down Syndrome Embryonic Stem Cells Reveals a Role for RUNX1 in Neural Differentiation. Stem Cell Reports (2016) 0.75
Triploid human embryonic stem cells derived from tripronuclear zygotes displayed pluripotency and trophoblast differentiation ability similar to the diploid human embryonic stem cells. J Reprod Dev (2016) 0.75
Modeling Developmental and Tumorigenic Aspects of Trilateral Retinoblastoma via Human Embryonic Stem Cells. Stem Cell Reports (2017) 0.75
Characterization of human embryonic stem cell lines by the International Stem Cell Initiative. Nat Biotechnol (2007) 9.36
Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures. Cell Stem Cell (2009) 8.62
UHRF1 plays a role in maintaining DNA methylation in mammalian cells. Science (2007) 7.90
Identification and classification of chromosomal aberrations in human induced pluripotent stem cells. Cell Stem Cell (2010) 7.16
Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage. Nat Biotechnol (2011) 3.97
Developmental programming of CpG island methylation profiles in the human genome. Nat Struct Mol Biol (2009) 3.96
Epigenetic memory and preferential lineage-specific differentiation in induced pluripotent stem cells derived from human pancreatic islet beta cells. Cell Stem Cell (2011) 3.73
Impact of tobacco control policies and mass media campaigns on monthly adult smoking prevalence. Am J Public Health (2008) 3.72
The tumorigenicity of human embryonic and induced pluripotent stem cells. Nat Rev Cancer (2011) 3.42
High-resolution DNA analysis of human embryonic stem cell lines reveals culture-induced copy number changes and loss of heterozygosity. Nat Biotechnol (2010) 3.21
Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells. Cell Stem Cell (2010) 3.08
Bone marrow-derived stem cells initiate pancreatic regeneration. Nat Biotechnol (2003) 3.02
Developmental study of fragile X syndrome using human embryonic stem cells derived from preimplantation genetically diagnosed embryos. Cell Stem Cell (2007) 2.87
Large-scale analysis reveals acquisition of lineage-specific chromosomal aberrations in human adult stem cells. Cell Stem Cell (2011) 2.71
Ethics. The ISSCR guidelines for human embryonic stem cell research. Science (2007) 2.62
Characterization of the expression of MHC proteins in human embryonic stem cells. Proc Natl Acad Sci U S A (2002) 2.53
Transcript annotation in FANTOM3: mouse gene catalog based on physical cDNAs. PLoS Genet (2006) 2.48
The tumorigenicity of human embryonic stem cells. Adv Cancer Res (2008) 2.32
Vitamin D insufficiency is associated with challenge-proven food allergy in infants. J Allergy Clin Immunol (2013) 2.31
Overexpression of NANOG in human ES cells enables feeder-free growth while inducing primitive ectoderm features. Development (2006) 2.27
The feasibility of voluntary counselling and HIV testing for pregnant women using community volunteers in Zimbabwe. Int J STD AIDS (2005) 2.27
Human embryonic stem cells and their differentiated derivatives are less susceptible to immune rejection than adult cells. Stem Cells (2005) 2.24
Guidelines for the diagnosis and management of cow's milk protein allergy in infants. Arch Dis Child (2007) 2.19
Residential radon and lung cancer--detailed results of a collaborative analysis of individual data on 7148 persons with lung cancer and 14,208 persons without lung cancer from 13 epidemiologic studies in Europe. Scand J Work Environ Health (2006) 2.18
Modeling for Lesch-Nyhan disease by gene targeting in human embryonic stem cells. Stem Cells (2004) 2.07
Selective elimination of human pluripotent stem cells by an oleate synthesis inhibitor discovered in a high-throughput screen. Cell Stem Cell (2013) 2.02
Clone- and gene-specific aberrations of parental imprinting in human induced pluripotent stem cells. Stem Cells (2009) 1.98
Selective ablation of human embryonic stem cells expressing a "suicide" gene. Stem Cells (2003) 1.75
Persistent and relapsing babesiosis in immunocompromised patients. Clin Infect Dis (2008) 1.71
Comparison of defined culture systems for feeder cell free propagation of human embryonic stem cells. In Vitro Cell Dev Biol Anim (2010) 1.70
Allergenicity assessment of genetically modified crops--what makes sense? Nat Biotechnol (2008) 1.67
WorfDB: the Caenorhabditis elegans ORFeome Database. Nucleic Acids Res (2003) 1.65
Assessing the safety of stem cell therapeutics. Cell Stem Cell (2011) 1.60
Differentiation and isolation of hepatic-like cells from human embryonic stem cells. Differentiation (2004) 1.53
The distribution and development of handedness for manual gestures in captive chimpanzees (Pan troglodytes). Psychol Sci (2005) 1.52
Increasing melanoma cell death using inhibitors of protein disulfide isomerases to abrogate survival responses to endoplasmic reticulum stress. Cancer Res (2008) 1.50
Temporal gene expression during differentiation of human embryonic stem cells and embryoid bodies. Hum Reprod (2004) 1.49
The management of early breast carcinoma before and after the introduction of clinical practice guidelines. Cancer (2004) 1.47
GoArrays: highly dynamic and efficient microarray probe design. Bioinformatics (2004) 1.44
Gene trap as a tool for genome annotation and analysis of X chromosome inactivation in human embryonic stem cells. Nucleic Acids Res (2004) 1.39
Changes in the management of ductal carcinoma in situ before the release of clinical practice recommendations in Australia: the case in Victoria. ANZ J Surg (2006) 1.39
The anti-apoptotic gene survivin contributes to teratoma formation by human embryonic stem cells. Nat Biotechnol (2009) 1.39
Derivation of euploid human embryonic stem cells from aneuploid embryos. Stem Cells (2008) 1.38
Genetic analysis of the role of the reprogramming gene LIN-28 in human embryonic stem cells. Stem Cells (2009) 1.30
Copy number variant analysis of human embryonic stem cells. Stem Cells (2008) 1.29
Meta-analysis of the heterogeneity of X chromosome inactivation in human pluripotent stem cells. Stem Cell Res (2010) 1.27
Quality control: Genome maintenance in pluripotent stem cells. J Cell Biol (2014) 1.27
The immunogenicity of human embryonic stem-derived cells. Trends Biotechnol (2004) 1.25
Dietary prevention of allergic diseases in infants and small children. Pediatr Allergy Immunol (2008) 1.24
Long-term inhibition of the glucagon receptor with a monoclonal antibody in mice causes sustained improvement in glycemic control, with reversible alpha-cell hyperplasia and hyperglucagonemia. J Pharmacol Exp Ther (2009) 1.22
The tumorigenicity of diploid and aneuploid human pluripotent stem cells. Cell Cycle (2009) 1.17
Targeted inhibition of calpain reduces myocardial hypertrophy and fibrosis in mouse models of type 1 diabetes. Diabetes (2011) 1.15
Taurine supplementation of a low protein diet fed to rat dams normalizes the vascularization of the fetal endocrine pancreas. J Nutr (2003) 1.15
Dietary prevention of allergic diseases in infants and small children. Part III: Critical review of published peer-reviewed observational and interventional studies and final recommendations. Pediatr Allergy Immunol (2004) 1.15
Variations of X chromosome inactivation occur in early passages of female human embryonic stem cells. PLoS One (2010) 1.13
Immunologic and chemical targeting of the tight-junction protein Claudin-6 eliminates tumorigenic human pluripotent stem cells. Nat Commun (2013) 1.12
Fibroblast growth factor 4 and its novel splice isoform have opposing effects on the maintenance of human embryonic stem cell self-renewal. Stem Cells (2008) 1.11
Virtual karyotyping of pluripotent stem cells on the basis of their global gene expression profiles. Nat Protoc (2013) 1.11
Ending inequities in access to effective pain relief? Lancet (2010) 1.09
From skin biopsy to neurons through a pluripotent intermediate under Good Manufacturing Practice protocols. Stem Cells Transl Med (2011) 1.07
Expanding the boundaries of embryonic stem cells. Cell Stem Cell (2012) 1.06
Dietary prevention of allergic diseases in infants and small children. Part II. Evaluation of methods in allergy prevention studies and sensitization markers. Definitions and diagnostic criteria of allergic diseases. Pediatr Allergy Immunol (2004) 1.06
The International Stem Cell Initiative: toward benchmarks for human embryonic stem cell research. Nat Biotechnol (2005) 1.06
Human embryonic stem cells as a cellular model for human disorders. Mol Cell Endocrinol (2006) 1.05
Chimpanzee (Pan troglodytes) intentional communication is not contingent upon food. Anim Cogn (2005) 1.03
Association between exposure to workplace secondhand smoke and reported respiratory and sensory symptoms: cross-sectional study. J Occup Environ Med (2003) 1.03
Publishing SNP genotypes of human embryonic stem cell lines: policy statement of the International Stem Cell Forum Ethics Working Party. Stem Cell Rev (2011) 1.02
Genomic stability in reprogramming. Curr Opin Genet Dev (2012) 1.02
Studying early lethality of 45,XO (Turner's syndrome) embryos using human embryonic stem cells. PLoS One (2009) 1.02
A molecular view on pluripotent stem cells. FEBS Lett (2002) 1.02
Reducing inequities in cancer care: the role of cancer registries. Cancer (2009) 1.01
High prevalence of evolutionarily conserved and species-specific genomic aberrations in mouse pluripotent stem cells. Stem Cells (2012) 1.01
Muscle Research and Gene Ontology: New standards for improved data integration. BMC Med Genomics (2009) 1.01
Study of hepatocyte differentiation using embryonic stem cells. J Cell Biochem (2005) 1.01
Disruption of mesodermal enhancers for Igf2 in the minute mutant. Development (2002) 1.00
Clonal analysis of human embryonic stem cell differentiation into teratomas. Stem Cells (2007) 1.00
Application of 6,7-indole aryne cycloaddition and Pd(0)-catalyzed Suzuki-Miyaura and Buchwald-Hartwig cross-coupling reactions for the preparation of annulated indole libraries. ACS Comb Sci (2011) 1.00
Integration and differentiation of human embryonic stem cells transplanted to the chick embryo. Dev Dyn (2002) 0.99
Long-term ovarian function and fertility after heterotopic autotransplantation of cryobanked human ovarian tissue: 8-year experience in cancer patients. Fertil Steril (2008) 0.98
Molecular analysis of LEFTY-expressing cells in early human embryoid bodies. Stem Cells (2006) 0.98
Coherent movement of cell layers during wound healing by image correlation spectroscopy. Biophys J (2009) 0.98
Molecular analysis of FMR1 reactivation in fragile-X induced pluripotent stem cells and their neuronal derivatives. J Mol Cell Biol (2012) 0.96
Improving adherence to surveillance and screening recommendations for people with colorectal cancer and their first degree relatives: a randomized controlled trial. BMC Cancer (2012) 0.96
Human embryonic stem cells as a model for early human development. Best Pract Res Clin Obstet Gynaecol (2004) 0.95