Published in Biophys J on July 21, 2010
Polymorphic structures of Alzheimer's β-amyloid globulomers. PLoS One (2011) 0.89
Opposing Effects of Cucurbit[7]uril and 1,2,3,4,6-Penta-O-galloyl-β-d-glucopyranose on Amyloid β25-35 Assembly. ACS Chem Neurosci (2015) 0.75
Molecular basis for the dissociation dynamics of protein A-immunoglobulin G1 complex. PLoS One (2013) 0.75
Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science (2003) 18.18
Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide. Nat Rev Mol Cell Biol (2007) 17.69
Knowledge-based protein secondary structure assignment. Proteins (1995) 14.08
Atomic structures of amyloid cross-beta spines reveal varied steric zippers. Nature (2007) 10.02
Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils. Science (2005) 8.86
PatchDock and SymmDock: servers for rigid and symmetric docking. Nucleic Acids Res (2005) 7.66
Soluble oligomers of the amyloid beta-protein impair synaptic plasticity and behavior. Behav Brain Res (2008) 5.29
Molecular structural basis for polymorphism in Alzheimer's beta-amyloid fibrils. Proc Natl Acad Sci U S A (2008) 4.84
Generalized born model with a simple smoothing function. J Comput Chem (2003) 4.36
Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases. J Biol Chem (2004) 4.33
Structural classification of toxic amyloid oligomers. J Biol Chem (2008) 4.16
Paradigm shifts in Alzheimer's disease and other neurodegenerative disorders: the emerging role of oligomeric assemblies. J Neurosci Res (2002) 3.79
Evidence of fibril-like β-sheet structures in a neurotoxic amyloid intermediate of Alzheimer's β-amyloid. Nat Struct Mol Biol (2007) 3.06
A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease. Proc Natl Acad Sci U S A (1994) 2.39
FireDock: a web server for fast interaction refinement in molecular docking. Nucleic Acids Res (2008) 2.39
Molecular dynamics simulations of spontaneous fibril formation by random-coil peptides. Proc Natl Acad Sci U S A (2004) 2.18
Annular protofibrils are a structurally and functionally distinct type of amyloid oligomer. J Biol Chem (2008) 2.04
Molecular dynamics simulations of Alzheimer's beta-amyloid protofilaments. J Mol Biol (2005) 1.99
Subcellular and metabolic examination of amyloid-beta peptides in Alzheimer disease pathogenesis: evidence for Abeta(25-35). Exp Neurol (2009) 1.75
Structural reorganisation and potential toxicity of oligomeric species formed during the assembly of amyloid fibrils. PLoS Comput Biol (2007) 1.71
Directed selection of a conformational antibody domain that prevents mature amyloid fibril formation by stabilizing Abeta protofibrils. Proc Natl Acad Sci U S A (2007) 1.68
Inhibition of toxicity in the beta-amyloid peptide fragment beta -(25-35) using N-methylated derivatives: a general strategy to prevent amyloid formation. J Biol Chem (2000) 1.44
Modeling the Alzheimer Abeta17-42 fibril architecture: tight intermolecular sheet-sheet association and intramolecular hydrated cavities. Biophys J (2007) 1.44
Role of water in mediating the assembly of Alzheimer amyloid-beta Abeta16-22 protofilaments. J Am Chem Soc (2008) 1.42
Structure determination of micelle-like intermediates in amyloid beta -protein fibril assembly by using small angle neutron scattering. Proc Natl Acad Sci U S A (2001) 1.41
Soluble amyloid beta-oligomers affect dielectric membrane properties by bilayer insertion and domain formation: implications for cell toxicity. Biophys J (2008) 1.36
Structural stability and dynamics of an amyloid-forming peptide GNNQQNY from the yeast prion sup-35. Biophys J (2006) 1.33
Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope. J Mol Biol (2008) 1.17
Dynamics of locking of peptides onto growing amyloid fibrils. Proc Natl Acad Sci U S A (2009) 1.15
Effect of dehydration on the aggregation kinetics of two amyloid peptides. J Phys Chem B (2009) 1.14
Residues 17-20 and 30-35 of beta-amyloid play critical roles in aggregation. J Neurosci Res (2004) 1.11
Annular structures as intermediates in fibril formation of Alzheimer Abeta17-42. J Phys Chem B (2008) 1.10
Solution structure of amyloid beta-peptide (25-35) in different media. J Med Chem (2004) 1.04
Effects of solvent on the structure of the Alzheimer amyloid-beta(25-35) peptide. Biophys J (2006) 1.04
Thermodynamics and dynamics of amyloid peptide oligomerization are sequence dependent. Proteins (2009) 1.03
A generic mechanism of emergence of amyloid protofilaments from disordered oligomeric aggregates. PLoS Comput Biol (2008) 1.02
Structures and thermodynamics of Alzheimer's amyloid-beta Abeta(16-35) monomer and dimer by replica exchange molecular dynamics simulations: implication for full-length Abeta fibrillation. J Phys Chem B (2009) 1.01
Evidence of the existence of micelles in the fibrillogenesis of beta-amyloid peptide. J Phys Chem B (2005) 0.99
Probing energetics of Abeta fibril elongation by molecular dynamics simulations. Biophys J (2009) 0.98
Probing the origins, diagnosis and treatment of amyloid diseases using antibodies. Biochimie (2004) 0.93
The stability of monomeric intermediates controls amyloid formation: Abeta25-35 and its N27Q mutant. Biophys J (2006) 0.87
A comparative study of beta-amyloid peptides Abeta1-42 and Abeta25-35 toxicity in organotypic hippocampal slice cultures. Neurochem Res (2008) 0.86
Molecular modeling of two distinct triangular oligomers in amyloid beta-protein. J Phys Chem B (2010) 0.86
Rapid aggregation and assembly in aqueous solution of A beta (25-35) peptide. J Biosci (2009) 0.85
Definition of amide protection factors for early kinetic intermediates in protein folding. Proc Natl Acad Sci U S A (1998) 0.84
Exploring interaction of beta-amyloid segment (25-35) with membrane models through paramagnetic probes. J Pept Sci (2006) 0.82
Oriented epitaxial growth of amyloid fibrils of the N27C mutant beta 25-35 peptide. Eur Biophys J (2008) 0.81
A beta 25-35 induces presynaptic changes in organotypic hippocampal slice cultures. Neurotoxicology (2008) 0.79
Effect of lysine-28 side-chain acetylation on the nanomechanical behavior of alzheimer amyloid beta25-35 fibrils. J Chem Inf Model (2005) 0.78
Large-scale sequence analysis of avian influenza isolates. Science (2006) 9.87
Rational design and characterization of a Rac GTPase-specific small molecule inhibitor. Proc Natl Acad Sci U S A (2004) 7.24
Modeling sample variables with an Experimental Factor Ontology. Bioinformatics (2010) 6.27
Patients' perception of hospital care in the United States. N Engl J Med (2008) 6.10
Modeling biomedical experimental processes with OBI. J Biomed Semantics (2010) 5.36
Pivotal role of dermal IL-17-producing γδ T cells in skin inflammation. Immunity (2011) 3.75
The structural biology of type II fatty acid biosynthesis. Annu Rev Biochem (2005) 3.69
Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21. Nat Genet (2009) 3.59
Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled. Mol Cell (2003) 3.06
Identification of a salmonellosis outbreak by means of molecular sequencing. N Engl J Med (2011) 2.81
Determinants of asthma after severe respiratory syncytial virus bronchiolitis. J Allergy Clin Immunol (2012) 2.27
Use of UpToDate and outcomes in US hospitals. J Hosp Med (2011) 2.19
3D MRI-based multicomponent FSI models for atherosclerotic plaques. Ann Biomed Eng (2004) 2.17
Electronic health records' limited successes suggest more targeted uses. Health Aff (Millwood) (2010) 2.17
Thermosensitive TRP channel pore turret is part of the temperature activation pathway. Proc Natl Acad Sci U S A (2010) 2.15
DNA-templated Ag nanocluster formation. J Am Chem Soc (2004) 2.13
Human epithelial cancers secrete immunoglobulin g with unidentified specificity to promote growth and survival of tumor cells. Cancer Res (2003) 2.00
Does affiliation of physician groups with one another produce higher quality primary care? J Gen Intern Med (2007) 1.93
Identification of a specific inhibitor of the dishevelled PDZ domain. Biochemistry (2005) 1.92
Local maximal stress hypothesis and computational plaque vulnerability index for atherosclerotic plaque assessment. Ann Biomed Eng (2005) 1.89
Sites of rupture in human atherosclerotic carotid plaques are associated with high structural stresses: an in vivo MRI-based 3D fluid-structure interaction study. Stroke (2009) 1.81
Airway remodeling measured by multidetector CT is increased in severe asthma and correlates with pathology. Chest (2008) 1.80
Electrochemical cues regulate assembly of the Frizzled/Dishevelled complex at the plasma membrane during planar epithelial polarization. Nat Cell Biol (2009) 1.80
The LRP5 high-bone-mass G171V mutation disrupts LRP5 interaction with Mesd. Mol Cell Biol (2004) 1.77
An antagonist of dishevelled protein-protein interaction suppresses beta-catenin-dependent tumor cell growth. Cancer Res (2007) 1.73
On the evolutionary history, population genetics and diversity among isolates of Salmonella Enteritidis PFGE pattern JEGX01.0004. PLoS One (2013) 1.69
Thermosensitive TRPV channel subunits coassemble into heteromeric channels with intermediate conductance and gating properties. J Gen Physiol (2007) 1.68
Assignment of orthologous genes via genome rearrangement. IEEE/ACM Trans Comput Biol Bioinform (2006) 1.66
Large movement in the C terminus of CLC-0 chloride channel during slow gating. Nat Struct Mol Biol (2006) 1.62
Multiple organ infection and the pathogenesis of SARS. J Exp Med (2005) 1.58
Distribution of lymphoid neoplasms in China: analysis of 4,638 cases according to the World Health Organization classification. Am J Clin Pathol (2012) 1.53
In Vivo/Ex Vivo MRI-Based 3D Non-Newtonian FSI Models for Human Atherosclerotic Plaques Compared with Fluid/Wall-Only Models. Comput Model Eng Sci (2007) 1.51
Amyopathic dermatomyositis or dermatomyositis-like skin disease: retrospective review of 16 cases with amyopathic dermatomyositis. Clin Rheumatol (2009) 1.47
GFP-based FRET analysis in live cells. Brain Res (2006) 1.46
Risk factors for late renal dysfunction after pediatric heart transplantation: a multi-institutional study. Pediatr Transplant (2011) 1.45
Models of beta-amyloid ion channels in the membrane suggest that channel formation in the bilayer is a dynamic process. Biophys J (2007) 1.44
Drug-target interaction prediction by learning from local information and neighbors. Bioinformatics (2012) 1.44
Crystal structures of the Dab homology domains of mouse disabled 1 and 2. J Biol Chem (2003) 1.43
Passive tumor targeting of renal-clearable luminescent gold nanoparticles: long tumor retention and fast normal tissue clearance. J Am Chem Soc (2013) 1.43
New structures help the modeling of toxic amyloidbeta ion channels. Trends Biochem Sci (2008) 1.43
Luminescent gold nanoparticles with efficient renal clearance. Angew Chem Int Ed Engl (2011) 1.41
Quantifying effects of plaque structure and material properties on stress distributions in human atherosclerotic plaques using 3D FSI models. J Biomech Eng (2005) 1.38
Introduction to the CSBio2014 special issue. J Bioinform Comput Biol (2015) 1.37
Key residues responsible for acyl carrier protein and beta-ketoacyl-acyl carrier protein reductase (FabG) interaction. J Biol Chem (2003) 1.36
The solution structure of acyl carrier protein from Mycobacterium tuberculosis. J Biol Chem (2002) 1.36
Characterization of the Kremen-binding site on Dkk1 and elucidation of the role of Kremen in Dkk-mediated Wnt antagonism. J Biol Chem (2008) 1.35
Effect of stenosis asymmetry on blood flow and artery compression: a three-dimensional fluid-structure interaction model. Ann Biomed Eng (2003) 1.34
Radiographic structural abnormalities associated with premature, natural hip-joint failure. J Bone Joint Surg Am (2011) 1.33
Systematic confirmation study of reported prostate cancer risk-associated single nucleotide polymorphisms in Chinese men. Cancer Sci (2011) 1.32
MALT lymphoma with t(14;18)(q32;q21)/IGH-MALT1 is characterized by strong cytoplasmic MALT1 and BCL10 expression. J Pathol (2005) 1.32
Structure-function based design of small molecule inhibitors targeting Rho family GTPases. Curr Top Med Chem (2006) 1.31
Protein adsorption on oligo(ethylene glycol)-terminated alkanethiolate self-assembled monolayers: The molecular basis for nonfouling behavior. J Phys Chem B (2005) 1.31
Electronic health records: use, barriers and satisfaction among physicians who care for black and Hispanic patients. J Eval Clin Pract (2008) 1.27
Multiple mechanisms for Wnt11-mediated repression of the canonical Wnt signaling pathway. J Biol Chem (2004) 1.27
Quantification of regional myocardial oxygenation by magnetic resonance imaging: validation with positron emission tomography. Circ Cardiovasc Imaging (2009) 1.27
Concurrent multimodality image segmentation by active contours for radiotherapy treatment planning. Med Phys (2007) 1.26
Strong resistance of phosphorylcholine self-assembled monolayers to protein adsorption: insights into nonfouling properties of zwitterionic materials. J Am Chem Soc (2005) 1.26
Graphene oxide stabilized polyethylene glycol for heat storage. Phys Chem Chem Phys (2012) 1.24
The crosstalk between EGF, IGF, and Insulin cell signaling pathways--computational and experimental analysis. BMC Syst Biol (2009) 1.24
Characterization of the Drosophila gene-switch system in aging studies: a cautionary tale. Aging Cell (2008) 1.23
Redirecting differentiation of hematopoietic progenitors by a transcription factor, GATA-2. Blood (2005) 1.23
In vivo IVUS-based 3-D fluid-structure interaction models with cyclic bending and anisotropic vessel properties for human atherosclerotic coronary plaque mechanical analysis. IEEE Trans Biomed Eng (2009) 1.23
MicroRNA-19 (miR-19) regulates tissue factor expression in breast cancer cells. J Biol Chem (2010) 1.23
PEGylation and zwitterionization: pros and cons in the renal clearance and tumor targeting of near-IR-emitting gold nanoparticles. Angew Chem Int Ed Engl (2013) 1.23
Sequence analysis of p53 response-elements suggests multiple binding modes of the p53 tetramer to DNA targets. Nucleic Acids Res (2007) 1.22
Fast mapping of myocardial blood flow with MR first-pass perfusion imaging. Magn Reson Med (2008) 1.22
Rational design and applications of a Rac GTPase-specific small molecule inhibitor. Methods Enzymol (2006) 1.22
Selective disruption of high sensitivity heat activation but not capsaicin activation of TRPV1 channels by pore turret mutations. J Gen Physiol (2012) 1.21
Does the Leapfrog program help identify high-quality hospitals? Jt Comm J Qual Patient Saf (2008) 1.21
Structural insight into the mechanisms of targeting and signaling of focal adhesion kinase. Mol Cell Biol (2002) 1.21
Hepatitis B virus X protein promotes liver cell proliferation via a positive cascade loop involving arachidonic acid metabolism and p-ERK1/2. Cell Res (2010) 1.19
Altered left ventricular geometry changes the border zone temporal distribution of stress in an experimental model of left ventricular aneurysm: a finite element model study. Circulation (2002) 1.18
3D MRI-based anisotropic FSI models with cyclic bending for human coronary atherosclerotic plaque mechanical analysis. J Biomech Eng (2009) 1.17
3D critical plaque wall stress is a better predictor of carotid plaque rupture sites than flow shear stress: An in vivo MRI-based 3D FSI study. J Biomech Eng (2010) 1.16
Intramyocardial injection of allogenic bone marrow-derived mesenchymal stem cells without immunosuppression preserves cardiac function in a porcine model of myocardial infarction. J Cardiovasc Pharmacol Ther (2005) 1.15
An experimental study on the ultimate strength of the adventitia and media of human atherosclerotic carotid arteries in circumferential and axial directions. J Biomech (2009) 1.15
Draft genome sequences of 21 Salmonella enterica serovar enteritidis strains. J Bacteriol (2012) 1.15
Replication and cumulative effects of GWAS-identified genetic variations for prostate cancer in Asians: a case-control study in the ChinaPCa consortium. Carcinogenesis (2011) 1.15
Improvement of quantification of myocardial first-pass perfusion mapping: a temporal and spatial wavelet denoising method. Magn Reson Med (2006) 1.15
Evidence of an emerging digital divide among hospitals that care for the poor. Health Aff (Millwood) (2009) 1.15
Interaction between the internal motif KTXXXI of Idax and mDvl PDZ domain. Biochem Biophys Res Commun (2004) 1.14
Near-infrared emitting radioactive gold nanoparticles with molecular pharmacokinetics. Angew Chem Int Ed Engl (2012) 1.14
The characteristics and performance of hospitals that care for elderly Hispanic Americans. Health Aff (Millwood) (2008) 1.13
Nanoparticle-free single molecule anti-stokes Raman spectroscopy. Phys Rev Lett (2005) 1.13
The third 20 amino acid repeat is the tightest binding site of APC for beta-catenin. J Mol Biol (2006) 1.13
Single-molecule optoelectronics. Acc Chem Res (2005) 1.13
Cardioprotective effect of fluvastatin on isoproterenol-induced myocardial infarction in rat. Eur J Pharmacol (2008) 1.12
Tongxinluo (Tong xin luo or Tong-xin-luo) capsule for unstable angina pectoris. Cochrane Database Syst Rev (2006) 1.11
Patient-specific artery shrinkage and 3D zero-stress state in multi-component 3D FSI models for carotid atherosclerotic plaques based on in vivo MRI data. Mol Cell Biomech (2009) 1.11
Molecular imaging of atherosclerotic plaque with (64)Cu-labeled natriuretic peptide and PET. J Nucl Med (2009) 1.09
Clinical manifestations of dermatomyositis and clinically amyopathic dermatomyositis patients with positive expression of anti-melanoma differentiation-associated gene 5 antibody. Arthritis Care Res (Hoboken) (2012) 1.08
Basal cell carcinoma does metastasize. Dermatol Online J (2008) 1.08
In vitro differentiation of mouse embryonic stem cells to hematopoietic cells on an OP9 stromal cell monolayer. Methods Enzymol (2003) 1.06
Structural features of the focal adhesion kinase-paxillin complex give insight into the dynamics of focal adhesion assembly. Protein Sci (2005) 1.06
Planar biaxial characterization of diseased human coronary and carotid arteries for computational modeling. J Biomech (2012) 1.05
EMMNet: sensor networking for electricity meter monitoring. Sensors (Basel) (2010) 1.05
Luminescent gold nanoparticles with pH-dependent membrane adsorption. J Am Chem Soc (2011) 1.04
Therapeutic effect of Fe2O3 nanoparticles combined with magnetic fluid hyperthermia on cultured liver cancer cells and xenograft liver cancers. J Nanosci Nanotechnol (2005) 1.04
Distinct regulatory mechanism of immunoglobulin gene transcription in epithelial cancer cells. Cell Mol Immunol (2010) 1.02