Published in J Biol Chem on July 22, 2010
Divergent roles of Smad3 and PI3-kinase in murine adriamycin nephropathy indicate distinct mechanisms of proteinuria and fibrogenesis. Kidney Int (2012) 1.66
Integrin-mediated type II TGF-β receptor tyrosine dephosphorylation controls SMAD-dependent profibrotic signaling. J Clin Invest (2014) 1.59
Matrix-dependent perturbation of TGFβ signaling and disease. FEBS Lett (2012) 1.31
Beta 1 integrin predicts survival in breast cancer: a clinicopathological and immunohistochemical study. Diagn Pathol (2012) 1.17
Cell-matrix adhesion of podocytes in physiology and disease. Nat Rev Nephrol (2013) 1.02
Podocyte injury-driven intracapillary plasminogen activator inhibitor type 1 accelerates podocyte loss via uPAR-mediated β1-integrin endocytosis. Am J Physiol Renal Physiol (2015) 0.92
Lung-specific loss of the laminin α3 subunit confers resistance to mechanical injury. J Cell Sci (2011) 0.89
Serine-204 in the linker region of Smad3 mediates the collagen-I response to TGF-β in a cell phenotype-specific manner. Exp Cell Res (2013) 0.83
Serial non-invasive monitoring of renal disease following immune-mediated injury using near-infrared optical imaging. PLoS One (2012) 0.79
Expression and activity of Rac1 is negatively affected in the dehydroepiandrosterone induced polycystic ovary of mouse. J Ovarian Res (2014) 0.79
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The phosphatidylinositol 3-kinase/Akt pathway enhances Smad3-stimulated mesangial cell collagen I expression in response to transforming growth factor-beta1. J Biol Chem (2003) 1.79
Beta1 integrin expression by podocytes is required to maintain glomerular structural integrity. Dev Biol (2008) 1.59
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alpha(v)beta(3) Integrin interacts with the transforming growth factor beta (TGFbeta) type II receptor to potentiate the proliferative effects of TGFbeta1 in living human lung fibroblasts. J Biol Chem (2004) 1.41
Microfilament-dependent movement of the beta3 integrin subunit within focal contacts of endothelial cells. FASEB J (2002) 1.34
Lack of integrin alpha1beta1 leads to severe glomerulosclerosis after glomerular injury. Am J Pathol (2004) 1.33
Transforming growth factor-beta switches the pattern of integrins expressed in MG-63 human osteosarcoma cells and causes a selective loss of cell adhesion to laminin. J Biol Chem (1989) 1.30
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Transforming growth factor beta1 induces alphavbeta3 integrin expression in human lung fibroblasts via a beta3 integrin-, c-Src-, and p38 MAPK-dependent pathway. J Biol Chem (2008) 1.20
FAK-dependent regulation of myofibroblast differentiation. FASEB J (2006) 1.17
Glomerular injury is exacerbated in diabetic integrin alpha1-null mice. Kidney Int (2006) 1.15
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Rac1 promotes TGF-beta-stimulated mesangial cell type I collagen expression through a PI3K/Akt-dependent mechanism. Am J Physiol Renal Physiol (2009) 1.06
Cross talk between beta(1) and alpha(V) integrins: beta(1) affects beta(3) mRNA stability. Mol Biol Cell (2001) 1.06
MAP-kinase activity necessary for TGFbeta1-stimulated mesangial cell type I collagen expression requires adhesion-dependent phosphorylation of FAK tyrosine 397. J Cell Sci (2007) 1.06
De novo expression of the integrin alpha5beta1 regulates alphavbeta3-mediated adhesion and migration on fibrinogen. J Biol Chem (2003) 1.00
Direct action of platelet activating factor (PAF) induces eosinophil accumulation and enhances expression of PAF receptors in conjunctivitis. Mol Vis (2005) 0.91
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Arg-Gly-Asp-Ser (RGDS) peptide stimulates transforming growth factor beta1 transcription and secretion through integrin activation. FASEB J (2003) 0.86
Cell adhesion molecules and the glomerulopathies. Am J Med (1999) 0.84
beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium. Cancer Cell (2002) 5.56
A simplified laminin nomenclature. Matrix Biol (2005) 3.81
A proposed taxonomy for the podocytopathies: a reassessment of the primary nephrotic diseases. Clin J Am Soc Nephrol (2007) 3.23
Cross-talk between ERK MAP kinase and Smad signaling pathways enhances TGF-beta-dependent responses in human mesangial cells. FASEB J (2003) 2.15
The phosphatidylinositol 3-kinase/Akt pathway enhances Smad3-stimulated mesangial cell collagen I expression in response to transforming growth factor-beta1. J Biol Chem (2003) 1.79
Divergent roles of Smad3 and PI3-kinase in murine adriamycin nephropathy indicate distinct mechanisms of proteinuria and fibrogenesis. Kidney Int (2012) 1.66
The vimentin cytoskeleton regulates focal contact size and adhesion of endothelial cells subjected to shear stress. J Cell Sci (2003) 1.59
Integrin beta4 regulates migratory behavior of keratinocytes by determining laminin-332 organization. J Biol Chem (2006) 1.55
Dynamic relationship of focal contacts and hemidesmosome protein complexes in live cells. J Invest Dermatol (2010) 1.52
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Recruitment of vimentin to the cell surface by beta3 integrin and plectin mediates adhesion strength. J Cell Sci (2009) 1.48
It's a Smad world: regulation of TGF-beta signaling in the kidney. J Am Soc Nephrol (2002) 1.39
The role of internalization in transforming growth factor beta1-induced Smad2 association with Smad anchor for receptor activation (SARA) and Smad2-dependent signaling in human mesangial cells. J Biol Chem (2004) 1.39
Tubulointerstitial injury and the progression of chronic kidney disease. Pediatr Nephrol (2011) 1.37
Microfilament-dependent movement of the beta3 integrin subunit within focal contacts of endothelial cells. FASEB J (2002) 1.34
Complex interactions between the laminin alpha 4 subunit and integrins regulate endothelial cell behavior in vitro and angiogenesis in vivo. Proc Natl Acad Sci U S A (2002) 1.31
Estrogens and the vascular endothelium. Ann N Y Acad Sci (2002) 1.31
Plakoglobin suppresses keratinocyte motility through both cell-cell adhesion-dependent and -independent mechanisms. Proc Natl Acad Sci U S A (2005) 1.29
The slingshot family of phosphatases mediates Rac1 regulation of cofilin phosphorylation, laminin-332 organization, and motility behavior of keratinocytes. J Biol Chem (2007) 1.27
Compositional differences between infant and adult human corneal basement membranes. Invest Ophthalmol Vis Sci (2007) 1.25
Wound healing is defective in mice lacking tetraspanin CD151. J Invest Dermatol (2006) 1.22
Smad3 and PKCdelta mediate TGF-beta1-induced collagen I expression in human mesangial cells. Am J Physiol Renal Physiol (2003) 1.22
Intermediate filament associated proteins. Adv Protein Chem (2005) 1.19
Laminin deposition in the extracellular matrix: a complex picture emerges. J Cell Sci (2009) 1.14
Laminin-332-integrin interaction: a target for cancer therapy? Curr Med Chem (2008) 1.11
The role of alpha3beta1 integrin in determining the supramolecular organization of laminin-5 in the extracellular matrix of keratinocytes. Exp Cell Res (2003) 1.09
Hemidesmosomes and focal contact proteins: functions and cross-talk in keratinocytes, bullous diseases and wound healing. J Dermatol Sci (2011) 1.09
Hemidesmosome protein dynamics in live epithelial cells. Cell Motil Cytoskeleton (2003) 1.08
BPAG1e maintains keratinocyte polarity through beta4 integrin-mediated modulation of Rac1 and cofilin activities. Mol Biol Cell (2009) 1.08
Plakoglobin regulates cell motility through Rho- and fibronectin-dependent Src signaling. J Cell Sci (2010) 1.08
Interdependence of HIF-1α and TGF-β/Smad3 signaling in normoxic and hypoxic renal epithelial cell collagen expression. Am J Physiol Renal Physiol (2011) 1.07
The barrier function of skin: how to keep a tight lid on water loss. Trends Cell Biol (2002) 1.06
Rac1 promotes TGF-beta-stimulated mesangial cell type I collagen expression through a PI3K/Akt-dependent mechanism. Am J Physiol Renal Physiol (2009) 1.06
MAP-kinase activity necessary for TGFbeta1-stimulated mesangial cell type I collagen expression requires adhesion-dependent phosphorylation of FAK tyrosine 397. J Cell Sci (2007) 1.06
Laminin-332 and -511 in skin. Exp Dermatol (2008) 1.02
Cell phenotype-specific down-regulation of Smad3 involves decreased gene activation as well as protein degradation. J Biol Chem (2007) 1.00
Role of SARA (SMAD anchor for receptor activation) in maintenance of epithelial cell phenotype. J Biol Chem (2009) 0.99
TGF-beta receptor-binding proteins: complex interactions. Cell Signal (2006) 0.98
α6β4 integrin, a master regulator of expression of integrins in human keratinocytes. J Biol Chem (2012) 0.95
Laminin-311 (Laminin-6) fiber assembly by type I-like alveolar cells. J Histochem Cytochem (2006) 0.94
A role for anti-BP180 autoantibodies in chronic rhinosinusitis. Laryngoscope (2013) 0.94
Cytoskeletal rearrangement and signal transduction in TGF-beta1-stimulated mesangial cell collagen accumulation. J Am Soc Nephrol (2003) 0.93
Hypoxia-inducible factor-2α and TGF-β signaling interact to promote normoxic glomerular fibrogenesis. Am J Physiol Renal Physiol (2013) 0.93
Type XVII collagen regulates lamellipod stability, cell motility, and signaling to Rac1 by targeting bullous pemphigoid antigen 1e to alpha6beta4 integrin. J Biol Chem (2011) 0.93
Crucial role of the specificity-determining loop of the integrin beta4 subunit in the binding of cells to laminin-5 and outside-in signal transduction. J Biol Chem (2003) 0.92
High ambient glucose enhances sensitivity to TGF-beta1 via extracellular signal--regulated kinase and protein kinase Cdelta activities in human mesangial cells. J Am Soc Nephrol (2004) 0.92
Laminin-511, inducer of hair growth, is down-regulated and its suppressor in hair growth, laminin-332 up-regulated in chemotherapy-induced alopecia. J Dermatol Sci (2010) 0.92
Stretch-induced activation of AMP kinase in the lung requires dystroglycan. Am J Respir Cell Mol Biol (2008) 0.91
Fibronectin expression determines skin cell motile behavior. J Invest Dermatol (2011) 0.91
Spatial and temporal control of laminin-332 (5) and -511 (10) expression during induction of anagen hair growth. J Histochem Cytochem (2006) 0.91
TGF-β/Smad3 activates mammalian target of rapamycin complex-1 to promote collagen production by increasing HIF-1α expression. Am J Physiol Renal Physiol (2013) 0.91
Caspase proteolysis of the integrin beta4 subunit disrupts hemidesmosome assembly, promotes apoptosis, and inhibits cell migration. J Biol Chem (2006) 0.91
Lung-specific loss of the laminin α3 subunit confers resistance to mechanical injury. J Cell Sci (2011) 0.89
Loss of adhesion-regulated proteinase production is correlated with invasive activity in oral squamous cell carcinoma. Cancer (2002) 0.89
Transdominant regulation of integrin function: mechanisms of crosstalk. Cell Signal (2009) 0.88
Adhesion and migration, the diverse functions of the laminin alpha3 subunit. Dermatol Clin (2010) 0.88
Actinin-4 in keratinocytes regulates motility via an effect on lamellipodia stability and matrix adhesions. FASEB J (2012) 0.86
Hypoxia regulates PDGF-B interactions between glomerular capillary endothelial and mesangial cells. Kidney Int (2005) 0.86
Integrin cross-talk in endothelial cells is regulated by protein kinase A and protein phosphatase 1. J Biol Chem (2008) 0.86
17 beta-estradiol transiently disrupts adherens junctions in endothelial cells. FASEB J (2005) 0.85
RACK1 binds to Smad3 to modulate transforming growth factor-beta1-stimulated alpha2(I) collagen transcription in renal tubular epithelial cells. J Biol Chem (2006) 0.84
A dystroglycan/plectin scaffold mediates mechanical pathway bifurcation in lung epithelial cells. J Biol Chem (2010) 0.83
14-3-3zeta/tau heterodimers regulate Slingshot activity in migrating keratinocytes. Biochem Biophys Res Commun (2009) 0.82
Function of laminins and laminin-binding integrins in gingival epithelial cell adhesion. J Periodontol (2002) 0.82
Bullous pemphigoid IgG induces BP180 internalization via a macropinocytic pathway. Am J Pathol (2013) 0.82
Plectin-containing, centrally localized focal adhesions exert traction forces in primary lung epithelial cells. J Cell Sci (2013) 0.80
High ambient glucose augments angiotensin II-induced proinflammatory gene mRNA expression in human mesangial cells: effects of valsartan and simvastatin. Am J Nephrol (2009) 0.79
Phosphatidylinositol 3-kinase and Rab5 GTPase inversely regulate the Smad anchor for receptor activation (SARA) protein independently of transforming growth factor-β1. J Biol Chem (2012) 0.79
Myosin-mediated cytoskeleton contraction and Rho GTPases regulate laminin-5 matrix assembly. Cell Motil Cytoskeleton (2004) 0.79
Identification of a novel family of laminin N-terminal alternate splice isoforms: structural and functional characterization. J Biol Chem (2009) 0.79
TGFβ receptor I transactivation mediates stretch-induced Pak1 activation and CTGF upregulation in mesangial cells. J Cell Sci (2013) 0.78
Laminin-332 and α3β1 integrin-supported migration of bronchial epithelial cells is modulated by fibronectin. Am J Respir Cell Mol Biol (2013) 0.78
Reduction of contamination of epithelial cultures by fibroblasts. CSH Protoc (2008) 0.77
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Fluorescently tagged laminin subunits facilitate analyses of the properties, assembly and processing of laminins in live and fixed lung epithelial cells and keratinocytes. Matrix Biol (2008) 0.76
Flii control: balancing migration and adhesion. J Invest Dermatol (2009) 0.76
14-3-3 sigma isoform interacts with the cytoplasmic domain of the transmembrane BP180 in keratinocytes. J Cell Physiol (2007) 0.76
Lung-specific loss of α3 laminin worsens bleomycin-induced pulmonary fibrosis. Am J Respir Cell Mol Biol (2015) 0.75
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