Published in Expert Rev Proteomics on August 01, 2010
Quality control of mitochondrial proteostasis. Cold Spring Harb Perspect Biol (2011) 1.55
Accumulation of Basic Amino Acids at Mitochondria Dictates the Cytotoxicity of Aberrant Ubiquitin. Cell Rep (2015) 1.54
Cell signaling and mitochondrial dynamics: Implications for neuronal function and neurodegenerative disease. Neurobiol Dis (2012) 1.05
Proteomics of protein post-translational modifications implicated in neurodegeneration. Transl Neurodegener (2014) 0.86
Ginkgo extract EGb 761(®) shields from slowly accumulating neurodegenerative-like changes in a newly developed cell culture model induced by the combined action of low doses of antimycin A1 and 2-deoxy-D-glucose. J Neural Transm (Vienna) (2011) 0.76
Drosophila as a potential model to ameliorate mutant Huntington-mediated cardiac amyloidosis. Rare Dis (2014) 0.75
In-depth phenotyping of lymphoblastoid cells suggests selective cellular vulnerability in Marinesco-Sjögren syndrome. Oncotarget (2017) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy (2007) 20.92
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Calreticulin exposure dictates the immunogenicity of cancer cell death. Nat Med (2006) 10.54
Ambra1 regulates autophagy and development of the nervous system. Nature (2007) 6.94
Mitotic phosphorylation of histone H3: spatio-temporal regulation by mammalian Aurora kinases. Mol Cell Biol (2002) 4.50
An immunosurveillance mechanism controls cancer cell ploidy. Science (2012) 4.35
Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells. J Clin Invest (2009) 3.23
AIF deficiency compromises oxidative phosphorylation. EMBO J (2004) 3.19
The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy. J Cell Biol (2010) 3.17
Transglutaminase 2: an enigmatic enzyme with diverse functions. Trends Biochem Sci (2002) 2.74
mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6. Nat Cell Biol (2013) 2.73
Mitochondrial BCL-2 inhibits AMBRA1-induced autophagy. EMBO J (2011) 1.68
Beclin1: a role in membrane dynamics and beyond. Autophagy (2012) 1.68
Gangliosides link the acidic sphingomyelinase-mediated induction of ceramide to 12-lipoxygenase-dependent apoptosis of neuroblastoma in response to fenretinide. J Natl Cancer Inst (2004) 1.64
Characterization of a new cancer-associated mutant of p53 with a missense mutation (K351N) in the tetramerization domain. Cell Cycle (2009) 1.57
Increasing melanoma cell death using inhibitors of protein disulfide isomerases to abrogate survival responses to endoplasmic reticulum stress. Cancer Res (2008) 1.50
Transglutaminase 2-/- mice reveal a phagocytosis-associated crosstalk between macrophages and apoptotic cells. Proc Natl Acad Sci U S A (2003) 1.48
Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV-1 envelope. EMBO J (2002) 1.42
Pro-apoptotic function of checkpoint kinase-2 in syncytia elicited by the HIV-1 envelope. Cell Cycle (2009) 1.41
Regulation of autophagy in mammals and its interplay with apoptosis. Cell Mol Life Sci (2010) 1.40
ESX-1 dependent impairment of autophagic flux by Mycobacterium tuberculosis in human dendritic cells. Autophagy (2012) 1.38
Cell death and autophagy: cytokines, drugs, and nutritional factors. Toxicology (2008) 1.31
Endoplasmic reticulum stress induces apoptosis by an apoptosome-dependent but caspase 12-independent mechanism. J Biol Chem (2005) 1.30
The splicing regulator Sam68 binds to a novel exonic splicing silencer and functions in SMN2 alternative splicing in spinal muscular atrophy. EMBO J (2010) 1.28
Extracellular ATP acts on P2Y2 purinergic receptors to facilitate HIV-1 infection. J Exp Med (2011) 1.22
Essential role of p53 phosphorylation by p38 MAPK in apoptosis induction by the HIV-1 envelope. J Exp Med (2005) 1.22
Nicotinic acid adenine dinucleotide phosphate (NAADP) regulates autophagy in cultured astrocytes. J Biol Chem (2011) 1.21
CREM-dependent transcription in male germ cells controlled by a kinesin. Science (2002) 1.20
GADD153 and 12-lipoxygenase mediate fenretinide-induced apoptosis of neuroblastoma. Cancer Res (2002) 1.16
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen. Proteomics (2009) 1.14
NF-kappaB and p53 are the dominant apoptosis-inducing transcription factors elicited by the HIV-1 envelope. J Exp Med (2004) 1.13
Proteomic analysis of human very low-density lipoprotein by two-dimensional gel electrophoresis and MALDI-TOF/TOF. Proteomics (2007) 1.10
AMBRA1 links autophagy to cell proliferation and tumorigenesis by promoting c-Myc dephosphorylation and degradation. Nat Cell Biol (2015) 1.09
Transglutaminase overexpression sensitizes neuronal cell lines to apoptosis by increasing mitochondrial membrane potential and cellular oxidative stress. J Neurochem (2002) 1.09
Transglutaminase 2 is involved in autophagosome maturation. Autophagy (2009) 1.08
A novel role for autophagy in neurodevelopment. Autophagy (2007) 1.07
Transglutaminase type II plays a protective role in hepatic injury. Am J Pathol (2003) 1.06
Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition. Clin Cancer Res (2011) 1.05
Fenretinide induces autophagic cell death in caspase-defective breast cancer cells. Autophagy (2008) 1.04
Tissue transglutaminase is a multifunctional BH3-only protein. J Biol Chem (2004) 1.04
Inhibition of HIV-1 replication in monocyte-derived macrophages by Mycobacterium tuberculosis. J Infect Dis (2004) 1.03
Immunogenic chemotherapy: discovery of a critical protein through proteomic analyses of tumor cells. Cancer Genomics Proteomics (2007) 1.03
"Tissue" transglutaminase contributes to the formation of disulphide bridges in proteins of mitochondrial respiratory complexes. Biochim Biophys Acta (2006) 1.02
Mechanisms of free-radical induction in relation to fenretinide-induced apoptosis of neuroblastoma. J Cell Biochem (2003) 1.01
Autophagy protects cells from HCV-induced defects in lipid metabolism. Gastroenterology (2011) 1.01
TG2 transamidating activity acts as a reostat controlling the interplay between apoptosis and autophagy. Amino Acids (2011) 1.00
The fragile X protein binds mRNAs involved in cancer progression and modulates metastasis formation. EMBO Mol Med (2013) 0.99
Production of fertile offspring from genetically infertile male mice. Proc Natl Acad Sci U S A (2004) 0.99
Transglutaminase type II is involved in the pathogenesis of endotoxic shock. J Immunol (2008) 0.98
Transcriptional control of the pvdS iron starvation sigma factor gene by the master regulator of sulfur metabolism CysB in Pseudomonas aeruginosa. Environ Microbiol (2010) 0.98
Genotype-dependent priming to self- and xeno-cannibalism in heterozygous and homozygous lymphoblasts from patients with Huntington's disease. J Neurochem (2006) 0.97
Why is autophagy important for melanoma? Molecular mechanisms and therapeutic implications. Semin Cancer Biol (2013) 0.97
Specific T cells restore the autophagic flux inhibited by Mycobacterium tuberculosis in human primary macrophages. J Infect Dis (2012) 0.96
Critical involvement of the ATM-dependent DNA damage response in the apoptotic demise of HIV-1-elicited syncytia. PLoS One (2008) 0.95
Mitochondrial apoptosis induced by the HIV-1 envelope. Ann N Y Acad Sci (2003) 0.94
Molecular mechanisms of fenretinide-induced apoptosis of neuroblastoma cells. Ann N Y Acad Sci (2004) 0.94
Activation of Vgamma9Vdelta2 T cells by non-peptidic antigens induces the inhibition of subgenomic HCV replication. Int Immunol (2005) 0.93
Reticulon-1C acts as a molecular switch between endoplasmic reticulum stress and genotoxic cell death pathway in human neuroblastoma cells. J Neurochem (2007) 0.93
p53-A pro-apoptotic signal transducer involved in AIDS. Biochem Biophys Res Commun (2005) 0.92
Transglutaminase type II is a key element in the regulation of the anti-inflammatory response elicited by apoptotic cell engulfment. J Immunol (2005) 0.90
Fenretinide: a p53-independent way to kill cancer cells. Biochem Biophys Res Commun (2005) 0.89
Glucosylceramide synthase and its functional interaction with RTN-1C regulate chemotherapeutic-induced apoptosis in neuroepithelioma cells. Cancer Res (2003) 0.88
EBV stimulates TLR- and autophagy-dependent pathways and impairs maturation in plasmacytoid dendritic cells: implications for viral immune escape. Eur J Immunol (2012) 0.88
Ambra1 knockdown in zebrafish leads to incomplete development due to severe defects in organogenesis. Autophagy (2013) 0.87