Published in Autophagy on January 24, 2013
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy (2016) 7.05
AMBRA1 links autophagy to cell proliferation and tumorigenesis by promoting c-Myc dephosphorylation and degradation. Nat Cell Biol (2014) 2.06
Autophagy is essential for cardiac morphogenesis during vertebrate development. Autophagy (2014) 0.90
Correlative light and electron microscopy imaging of autophagy in a zebrafish infection model. Autophagy (2014) 0.80
Morpholino treatment improves muscle function and pathology of Pitx1 transgenic mice. Mol Ther (2013) 0.76
Manipulating galectin expression in zebrafish (Danio rerio). Methods Mol Biol (2015) 0.76
Zebrafish ambra1a and ambra1b knockdown impairs skeletal muscle development. PLoS One (2014) 0.76
Ambra1 spatially regulates Src activity and Src/FAK-mediated cancer cell invasion via trafficking networks. Elife (2017) 0.75
Mitophagy and Alzheimer's Disease: Cellular and Molecular Mechanisms. Trends Neurosci (2017) 0.75
Studying Autophagy in Zebrafish. Cells (2017) 0.75
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res (1994) 392.47
RAxML-VI-HPC: maximum likelihood-based phylogenetic analyses with thousands of taxa and mixed models. Bioinformatics (2006) 87.59
The rapid generation of mutation data matrices from protein sequences. Comput Appl Biosci (1992) 44.38
Stages of embryonic development of the zebrafish. Dev Dyn (1995) 42.72
Autophagy in the pathogenesis of disease. Cell (2008) 34.68
Autophagy fights disease through cellular self-digestion. Nature (2008) 33.83
The role of autophagy during the early neonatal starvation period. Nature (2004) 22.40
Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice. J Cell Biol (2005) 18.60
Network organization of the human autophagy system. Nature (2010) 11.38
High-resolution in situ hybridization to whole-mount zebrafish embryos. Nat Protoc (2008) 10.25
Potential therapeutic applications of autophagy. Nat Rev Drug Discov (2007) 8.56
Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages. Nat Cell Biol (2009) 7.35
Ambra1 regulates autophagy and development of the nervous system. Nature (2007) 6.94
p53 activation by knockdown technologies. PLoS Genet (2007) 6.85
The role of autophagy in mammalian development: cell makeover rather than cell death. Dev Cell (2008) 4.25
From 2R to 3R: evidence for a fish-specific genome duplication (FSGD). Bioessays (2005) 3.91
A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos. Cell (1993) 3.90
The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy. J Cell Biol (2010) 3.17
Aggregate-prone proteins are cleared from the cytosol by autophagy: therapeutic implications. Curr Top Dev Biol (2006) 3.02
Autophagy is defective in collagen VI muscular dystrophies, and its reactivation rescues myofiber degeneration. Nat Med (2010) 3.01
Subfunction partitioning, the teleost radiation and the annotation of the human genome. Trends Genet (2004) 2.71
Genome evolution and biodiversity in teleost fish. Heredity (Edinb) (2005) 2.65
Autophagy in yeast: a review of the molecular machinery. Cell Struct Funct (2002) 2.09
Automated identification of conserved synteny after whole-genome duplication. Genome Res (2009) 2.05
Mammalian macroautophagy at a glance. J Cell Sci (2009) 1.78
Zebrafish angiogenesis: a new model for drug screening. Angiogenesis (1999) 1.74
Expression of zebrafish goosecoid and no tail gene products in wild-type and mutant no tail embryos. Development (1994) 1.57
Assaying autophagic activity in transgenic GFP-Lc3 and GFP-Gabarap zebrafish embryos. Autophagy (2009) 1.57
Autophagy, a guardian against neurodegeneration. Semin Cell Dev Biol (2010) 1.45
Regulation of autophagy in mammals and its interplay with apoptosis. Cell Mol Life Sci (2010) 1.40
Differential regulation of chordin expression domains in mutant zebrafish. Dev Biol (1997) 1.27
Proteolysis of Ambra1 during apoptosis has a role in the inhibition of the autophagic pro-survival response. Cell Death Differ (2012) 1.08
The role of autophagy during development in higher eukaryotes. Traffic (2010) 0.97
Atg14L and Rubicon: yin and yang of Beclin 1-mediated autophagy control. Autophagy (2009) 0.90
Expression pattern and functions of autophagy-related gene atg5 in zebrafish organogenesis. Autophagy (2011) 0.90
Aging and TOR: interwoven in the fabric of life. Cell Mol Life Sci (2010) 0.87
Interplay between autophagy and apoptosis in the development of Danio rerio follicles and the effects of a probiotic. Reprod Fertil Dev (2013) 0.84
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy (2007) 20.92
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Calreticulin exposure dictates the immunogenicity of cancer cell death. Nat Med (2006) 10.54
Ambra1 regulates autophagy and development of the nervous system. Nature (2007) 6.94
Mitotic phosphorylation of histone H3: spatio-temporal regulation by mammalian Aurora kinases. Mol Cell Biol (2002) 4.50
An immunosurveillance mechanism controls cancer cell ploidy. Science (2012) 4.35
Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells. J Clin Invest (2009) 3.23
AIF deficiency compromises oxidative phosphorylation. EMBO J (2004) 3.19
The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy. J Cell Biol (2010) 3.17
Transglutaminase 2: an enigmatic enzyme with diverse functions. Trends Biochem Sci (2002) 2.74
mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6. Nat Cell Biol (2013) 2.73
Mitochondrial BCL-2 inhibits AMBRA1-induced autophagy. EMBO J (2011) 1.68
Beclin1: a role in membrane dynamics and beyond. Autophagy (2012) 1.68
Gangliosides link the acidic sphingomyelinase-mediated induction of ceramide to 12-lipoxygenase-dependent apoptosis of neuroblastoma in response to fenretinide. J Natl Cancer Inst (2004) 1.64
Characterization of a new cancer-associated mutant of p53 with a missense mutation (K351N) in the tetramerization domain. Cell Cycle (2009) 1.57
Increasing melanoma cell death using inhibitors of protein disulfide isomerases to abrogate survival responses to endoplasmic reticulum stress. Cancer Res (2008) 1.50
Transglutaminase 2-/- mice reveal a phagocytosis-associated crosstalk between macrophages and apoptotic cells. Proc Natl Acad Sci U S A (2003) 1.48
Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV-1 envelope. EMBO J (2002) 1.42
Pro-apoptotic function of checkpoint kinase-2 in syncytia elicited by the HIV-1 envelope. Cell Cycle (2009) 1.41
Regulation of autophagy in mammals and its interplay with apoptosis. Cell Mol Life Sci (2010) 1.40
ESX-1 dependent impairment of autophagic flux by Mycobacterium tuberculosis in human dendritic cells. Autophagy (2012) 1.38
Cell death and autophagy: cytokines, drugs, and nutritional factors. Toxicology (2008) 1.31
Endoplasmic reticulum stress induces apoptosis by an apoptosome-dependent but caspase 12-independent mechanism. J Biol Chem (2005) 1.30
Identification of reptilian genes encoding hair keratin-like proteins suggests a new scenario for the evolutionary origin of hair. Proc Natl Acad Sci U S A (2008) 1.29
The splicing regulator Sam68 binds to a novel exonic splicing silencer and functions in SMN2 alternative splicing in spinal muscular atrophy. EMBO J (2010) 1.28
Evolution of hard proteins in the sauropsid integument in relation to the cornification of skin derivatives in amniotes. J Anat (2009) 1.25
Extracellular ATP acts on P2Y2 purinergic receptors to facilitate HIV-1 infection. J Exp Med (2011) 1.22
Essential role of p53 phosphorylation by p38 MAPK in apoptosis induction by the HIV-1 envelope. J Exp Med (2005) 1.22
Nicotinic acid adenine dinucleotide phosphate (NAADP) regulates autophagy in cultured astrocytes. J Biol Chem (2011) 1.21
CREM-dependent transcription in male germ cells controlled by a kinesin. Science (2002) 1.20
GADD153 and 12-lipoxygenase mediate fenretinide-induced apoptosis of neuroblastoma. Cancer Res (2002) 1.16
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen. Proteomics (2009) 1.14
Microbial manipulations to improve fish health and production--a Mediterranean perspective. Fish Shellfish Immunol (2010) 1.14
NF-kappaB and p53 are the dominant apoptosis-inducing transcription factors elicited by the HIV-1 envelope. J Exp Med (2004) 1.13
Proteomic analysis of human very low-density lipoprotein by two-dimensional gel electrophoresis and MALDI-TOF/TOF. Proteomics (2007) 1.10
AMBRA1 links autophagy to cell proliferation and tumorigenesis by promoting c-Myc dephosphorylation and degradation. Nat Cell Biol (2015) 1.09
Transglutaminase overexpression sensitizes neuronal cell lines to apoptosis by increasing mitochondrial membrane potential and cellular oxidative stress. J Neurochem (2002) 1.09
Transglutaminase 2 is involved in autophagosome maturation. Autophagy (2009) 1.08
A novel role for autophagy in neurodevelopment. Autophagy (2007) 1.07
Transglutaminase type II plays a protective role in hepatic injury. Am J Pathol (2003) 1.06
Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition. Clin Cancer Res (2011) 1.05
Tissue transglutaminase is a multifunctional BH3-only protein. J Biol Chem (2004) 1.04
Fenretinide induces autophagic cell death in caspase-defective breast cancer cells. Autophagy (2008) 1.04
Inhibition of HIV-1 replication in monocyte-derived macrophages by Mycobacterium tuberculosis. J Infect Dis (2004) 1.03
Immunogenic chemotherapy: discovery of a critical protein through proteomic analyses of tumor cells. Cancer Genomics Proteomics (2007) 1.03
"Tissue" transglutaminase contributes to the formation of disulphide bridges in proteins of mitochondrial respiratory complexes. Biochim Biophys Acta (2006) 1.02
Mechanisms of free-radical induction in relation to fenretinide-induced apoptosis of neuroblastoma. J Cell Biochem (2003) 1.01
Autophagy protects cells from HCV-induced defects in lipid metabolism. Gastroenterology (2011) 1.01
Laticifers in Camptotheca acuminata Decne: distribution and structure. Protoplasma (2005) 1.01
TG2 transamidating activity acts as a reostat controlling the interplay between apoptosis and autophagy. Amino Acids (2011) 1.00
The fragile X protein binds mRNAs involved in cancer progression and modulates metastasis formation. EMBO Mol Med (2013) 0.99
Production of fertile offspring from genetically infertile male mice. Proc Natl Acad Sci U S A (2004) 0.99
Transglutaminase type II is involved in the pathogenesis of endotoxic shock. J Immunol (2008) 0.98
Transcriptional control of the pvdS iron starvation sigma factor gene by the master regulator of sulfur metabolism CysB in Pseudomonas aeruginosa. Environ Microbiol (2010) 0.98
Genotype-dependent priming to self- and xeno-cannibalism in heterozygous and homozygous lymphoblasts from patients with Huntington's disease. J Neurochem (2006) 0.97
Why is autophagy important for melanoma? Molecular mechanisms and therapeutic implications. Semin Cancer Biol (2013) 0.97
Specific T cells restore the autophagic flux inhibited by Mycobacterium tuberculosis in human primary macrophages. J Infect Dis (2012) 0.96
Hard cornification in reptilian epidermis in comparison to cornification in mammalian epidermis. Exp Dermatol (2007) 0.96
Phylogeny of betanodaviruses and molecular evolution of their RNA polymerase and coat proteins. Mol Phylogenet Evol (2006) 0.96
Effect of dietary probiotics on clownfish: a molecular approach to define how lactic acid bacteria modulate development in a marine fish. Am J Physiol Regul Integr Comp Physiol (2009) 0.95
Critical involvement of the ATM-dependent DNA damage response in the apoptotic demise of HIV-1-elicited syncytia. PLoS One (2008) 0.95
Hard (Beta-)keratins in the epidermis of reptiles: composition, sequence, and molecular organization. J Proteome Res (2007) 0.94
Mitochondrial apoptosis induced by the HIV-1 envelope. Ann N Y Acad Sci (2003) 0.94
Molecular mechanisms of fenretinide-induced apoptosis of neuroblastoma cells. Ann N Y Acad Sci (2004) 0.94
Activation of Vgamma9Vdelta2 T cells by non-peptidic antigens induces the inhibition of subgenomic HCV replication. Int Immunol (2005) 0.93