Emerging interface between metabolic syndrome and asthma.

PubWeight™: 0.95‹?› | Rank: Top 15%

🔗 View Article (PMID 20656947)

Published in Am J Respir Cell Mol Biol on July 23, 2010

Authors

Anurag Agrawal1, Ulaganathan Mabalirajan, Tanveer Ahmad, Balaram Ghosh

Author Affiliations

1: Centre for Translational Research in Asthma & Lung disease, Institute of Genomics & Integrative Biology, Delhi, India. a.agrawal@igib.in

Articles citing this

Metabolic pathways in T cell fate and function. Trends Immunol (2012) 1.97

Obesity impairs apoptotic cell clearance in asthma. J Allergy Clin Immunol (2012) 0.98

Insulin resistance, metabolic syndrome, and lung function in US adolescents with and without asthma. J Allergy Clin Immunol (2015) 0.95

Loss-of-function of inositol polyphosphate-4-phosphatase reversibly increases the severity of allergic airway inflammation. Nat Commun (2012) 0.93

Insulin and the lung: connecting asthma and metabolic syndrome. J Allergy (Cairo) (2013) 0.89

PTP1B deficiency exacerbates inflammation and accelerates leukocyte trafficking in vivo. J Immunol (2011) 0.85

Mitochondrial dysfunction in metabolic syndrome and asthma. J Allergy (Cairo) (2013) 0.84

Vasomotor regulation of coronary microcirculation by oxidative stress: role of arginase. Front Immunol (2013) 0.83

Alveolar-capillary adaptation to chronic hypoxia in the fatty lung. Acta Physiol (Oxf) (2014) 0.81

Asthma and metabolic syndrome: Current knowledge and future perspectives. World J Clin Cases (2015) 0.80

Metabolic Syndrome Is Associated with Increased Oxo-Nitrative Stress and Asthma-Like Changes in Lungs. PLoS One (2015) 0.80

Multitracer stable isotope quantification of arginase and nitric oxide synthase activity in a mouse model of pseudomonas lung infection. Mediators Inflamm (2014) 0.79

Obesity induced by neonatal overfeeding worsens airway hyperresponsiveness and inflammation. PLoS One (2012) 0.79

Emerging Comorbidities in Adult Asthma: Risks, Clinical Associations, and Mechanisms. Mediators Inflamm (2016) 0.77

Obesity, metabolic syndrome, and airway disease: a bioenergetic problem? Immunol Allergy Clin North Am (2014) 0.77

Hyperinsulinemia adversely affects lung structure and function. Am J Physiol Lung Cell Mol Physiol (2016) 0.75

Metabolic consequences of snoring in adolescents and younger adults: a population study in Chile. Int J Obes (Lond) (2016) 0.75

Emerging concepts in smooth muscle contributions to airway structure and function: implications for health and disease. Am J Physiol Lung Cell Mol Physiol (2016) 0.75

The effect of obesity, weight gain, and weight loss on asthma inception and control. Curr Opin Allergy Clin Immunol (2016) 0.75

Articles by these authors

4-Nitro-N'-[(E)-3-pyridylmethyl-idene]benzohydrazide. Acta Crystallogr Sect E Struct Rep Online (2010) 3.17

4-Nitro-N'-[(1E,2E)-3-phenyl-prop-2-en-1-yl-idene]benzohydrazide. Acta Crystallogr Sect E Struct Rep Online (2010) 2.19

Posttranscriptional regulation of interleukin-10 expression by hsa-miR-106a. Proc Natl Acad Sci U S A (2009) 1.64

Let-7 microRNA-mediated regulation of IL-13 and allergic airway inflammation. J Allergy Clin Immunol (2011) 1.58

FoxP3+ regulatory T cells suppress effector T-cell function at pathologic site in miliary tuberculosis. Am J Respir Crit Care Med (2009) 1.43

Miro1 regulates intercellular mitochondrial transport & enhances mesenchymal stem cell rescue efficacy. EMBO J (2014) 1.37

Mitochondrial structural changes and dysfunction are associated with experimental allergic asthma. J Immunol (2008) 1.32

Genetic association of acidic mammalian chitinase with atopic asthma and serum total IgE levels. J Allergy Clin Immunol (2008) 1.20

Synapse microarray identification of small molecules that enhance synaptogenesis. Nat Commun (2011) 1.19

Crebinostat: a novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity. Neuropharmacology (2012) 1.18

MicroRNA-326 regulates profibrotic functions of transforming growth factor-β in pulmonary fibrosis. Am J Respir Cell Mol Biol (2014) 1.14

Bioisosteric heterocyclic versions of 7-{[2-(4-phenyl-piperazin-1-yl)ethyl]propylamino}-5,6,7,8-tetrahydronaphthalen-2-ol: identification of highly potent and selective agonists for dopamine D3 receptor with potent in vivo activity. J Med Chem (2008) 1.14

Glycyrrhizin alleviates experimental allergic asthma in mice. Int Immunopharmacol (2006) 1.12

Effect of Inhibiting Histone Deacetylase with Short-Chain Carboxylic Acids and Their Hydroxamic Acid Analogs on Vertebrate Development and Neuronal Chromatin. ACS Med Chem Lett (2010) 1.11

Further structure-activity relationships study of hybrid 7-{[2-(4-phenylpiperazin-1-yl)ethyl]propylamino}-5,6,7,8-tetrahydronaphthalen-2-ol analogues: identification of a high-affinity D3-preferring agonist with potent in vivo activity with long duration of action. J Med Chem (2007) 1.11

Association of TNF haplotypes with asthma, serum IgE levels, and correlation with serum TNF-alpha levels. Am J Respir Cell Mol Biol (2006) 1.11

Beneficial effects of high dose of L-arginine on airway hyperresponsiveness and airway inflammation in a murine model of asthma. J Allergy Clin Immunol (2010) 1.08

Simvastatin improves epithelial dysfunction and airway hyperresponsiveness: from asymmetric dimethyl-arginine to asthma. Am J Respir Cell Mol Biol (2010) 1.07

Curcumin attenuates allergen-induced airway hyperresponsiveness in sensitized guinea pigs. Biol Pharm Bull (2003) 1.07

Proinflammatory role of epithelial cell-derived exosomes in allergic airway inflammation. J Allergy Clin Immunol (2013) 1.05

Altered asymmetric dimethyl arginine metabolism in allergically inflamed mouse lungs. Am J Respir Cell Mol Biol (2009) 1.04

Polarized helper T cells in tubercular pleural effusion: phenotypic identity and selective recruitment. Eur J Immunol (2005) 1.03

Linoleic acid metabolite drives severe asthma by causing airway epithelial injury. Sci Rep (2013) 1.02

Isoliquiritigenin inhibits IkappaB kinase activity and ROS generation to block TNF-alpha induced expression of cell adhesion molecules on human endothelial cells. Biochem Pharmacol (2007) 0.99

Mepacrine inhibits subepithelial fibrosis by reducing the expression of arginase and TGF-beta1 in an extended subacute mouse model of allergic asthma. Am J Physiol Lung Cell Mol Physiol (2009) 0.99

Hypoxia response in asthma: differential modulation on inflammation and epithelial injury. Am J Respir Cell Mol Biol (2012) 0.98

D-161, a novel pyran-based triple monoamine transporter blocker: behavioral pharmacological evidence for antidepressant-like action. Eur J Pharmacol (2008) 0.97

TGFbeta1 haplotypes and asthma in Indian populations. J Allergy Clin Immunol (2005) 0.97

Apoptogenic effect of 7,8-diacetoxy-4-methylcoumarin and 7,8-diacetoxy-4-methylthiocoumarin in human lung adenocarcinoma cell line: role of NF-kappaB, Akt, ROS and MAP kinase pathway. Chem Biol Interact (2008) 0.96

Genetic polymorphisms in TNF genes and tuberculosis in North Indians. BMC Infect Dis (2010) 0.96

Association of inducible nitric oxide synthase with asthma severity, total serum immunoglobulin E and blood eosinophil levels. Thorax (2007) 0.96

Synthesis, screening and quantitative structure-activity relationship (QSAR) studies of some glutamine analogues for possible anticancer activity. Bioorg Med Chem (2002) 0.96

Antagonism of mmu-mir-106a attenuates asthma features in allergic murine model. J Appl Physiol (1985) (2012) 0.96

Suggestive evidence of association of C-159T functional polymorphism of the CD14 gene with atopic asthma in northern and northwestern Indian populations. Immunogenetics (2004) 0.95

7,8-Dihydroxy-4-methylcoumarin induces apoptosis of human lung adenocarcinoma cells by ROS-independent mitochondrial pathway through partial inhibition of ERK/MAPK signaling. FEBS Lett (2007) 0.94

Esculetin restores mitochondrial dysfunction and reduces allergic asthma features in experimental murine model. J Immunol (2009) 0.94

TRPV1 inhibition attenuates IL-13 mediated asthma features in mice by reducing airway epithelial injury. Int Immunopharmacol (2013) 0.93

Loss-of-function of inositol polyphosphate-4-phosphatase reversibly increases the severity of allergic airway inflammation. Nat Commun (2012) 0.93

L-arginine reduces mitochondrial dysfunction and airway injury in murine allergic airway inflammation. Int Immunopharmacol (2010) 0.91

SIRT1 protects against cigarette smoke-induced lung oxidative stress via a FOXO3-dependent mechanism. Am J Physiol Lung Cell Mol Physiol (2014) 0.91

Piperine inhibits TNF-alpha induced adhesion of neutrophils to endothelial monolayer through suppression of NF-kappaB and IkappaB kinase activation. Eur J Pharmacol (2007) 0.91

Piper longum Linn. Extract inhibits TNF-alpha-induced expression of cell adhesion molecules by inhibiting NF-kappaB activation and microsomal lipid peroxidation. Phytomedicine (2007) 0.90

Effects of vitamin E on mitochondrial dysfunction and asthma features in an experimental allergic murine model. J Appl Physiol (1985) (2009) 0.89

Th(2) immune response in patients with dengue during defervescence: preliminary evidence. Am J Trop Med Hyg (2005) 0.88

Decreased mRNA and Protein Expression of BDNF, NGF, and their Receptors in the Hippocampus from Suicide: An Analysis in Human Postmortem Brain. Clin Med Insights Pathol (2013) 0.88

12/15-lipoxygenase expressed in non-epithelial cells causes airway epithelial injury in asthma. Sci Rep (2013) 0.88

A hexanucleotide repeat upstream of eotaxin gene promoter is associated with asthma, serum total IgE and plasma eotaxin levels. J Med Genet (2007) 0.88

A comparative study of efficacy and safety of gabapentin versus amitriptyline as coanalgesics in patients receiving opioid analgesics for neuropathic pain in malignancy. Indian J Pharmacol (2013) 0.87

A common exonic variant of interleukin21 confers susceptibility to atopic asthma. Int Arch Allergy Immunol (2008) 0.86

Arylamine N-acetyltransferase gene polymorphisms: markers for atopic asthma, serum IgE and blood eosinophil counts. Pharmacogenomics (2006) 0.86

Novel thiocoumarins as inhibitors of TNF-alpha induced ICAM-1 expression on human umbilical vein endothelial cells (HUVECs) and microsomal lipid peroxidation. Bioorg Med Chem (2005) 0.86

Monoalkoxy BODIPYs--a fluorophore class for bioimaging. Bioconjug Chem (2014) 0.86

Resveratrol regulates antioxidant status, inhibits cytokine expression and restricts apoptosis in carbon tetrachloride induced rat hepatic injury. Oxid Med Cell Longev (2011) 0.86

Association of a chromosome 1q21 locus in close proximity to a late cornified envelope-like proline-rich 1 (LELP1) gene with total serum IgE levels. J Hum Genet (2007) 0.85

Lack of association of histamine-N-methyltransferase (HNMT) polymorphisms with asthma in the Indian population. J Hum Genet (2005) 0.85

Diferuloylmethane inhibits neutrophil infiltration and improves survival of mice in high-dose endotoxin shock. Shock (2003) 0.85

N-acetyltransferases as markers for asthma and allergic/atopic disorders. Curr Drug Metab (2008) 0.84

Mitochondrial dysfunction in metabolic syndrome and asthma. J Allergy (Cairo) (2013) 0.84

Ethyl gallate attenuates acute lung injury through Nrf2 signaling. Biochimie (2013) 0.83

Genetics of asthma: a molecular biologist perspective. Clin Mol Allergy (2009) 0.83

Novel aromatic ester from Piper longum and its analogues inhibit expression of cell adhesion molecules on endothelial cells. Biochemistry (2005) 0.83

Baicalein reduces airway injury in allergen and IL-13 induced airway inflammation. PLoS One (2013) 0.82

A genetic variation in inositol polyphosphate 4 phosphatase a enhances susceptibility to asthma. Am J Respir Crit Care Med (2008) 0.82

Signal transducer and activator of transcription 6 haplotypes and asthma in the Indian population. Am J Respir Cell Mol Biol (2004) 0.81

Association of IL4 gene polymorphisms with asthma in North Indians. Int Arch Allergy Immunol (2004) 0.81

Inducible nitric oxide synthase (iNOS): role in asthma pathogenesis. Indian J Biochem Biophys (2007) 0.81

Ultrastructural changes of airway in murine models of allergy and diet-induced metabolic syndrome. ISRN Allergy (2013) 0.81

Vanadium induces apoptosis and modulates the expressions of metallothionein, Ki-67 nuclear antigen, and p53 during 2-acetylaminofluorene-induced rat liver preneoplasia. J Cell Biochem (2005) 0.81

A novel (TG)n(GA)m repeat polymorphism 254 bp downstream of the mast cell chymase (CMA1) gene is associated with atopic asthma and total serum IgE levels. J Hum Genet (2005) 0.81

TCEB3C a putative tumor suppressor gene of small intestinal neuroendocrine tumors. Endocr Relat Cancer (2014) 0.81

Mepacrine alleviates airway hyperresponsiveness and airway inflammation in a mouse model of asthma. Int Immunopharmacol (2008) 0.81

Suppression of cell proliferation, induction of apoptosis and cell cycle arrest: chemopreventive activity of vanadium in vivo and in vitro. Int J Cancer (2007) 0.80

Genetic contribution of chemokine receptor 2 (CCR2) polymorphisms towards increased serum total IgE levels in Indian asthmatics. Genomics (2009) 0.80

Regulation of NF-κB activation through a novel PI-3K-independent and PKA/Akt-dependent pathway in human umbilical vein endothelial cells. PLoS One (2012) 0.80

Uteroglobin-related protein 1(UGRP1) gene polymorphisms and atopic asthma in the Indian population. Int Arch Allergy Immunol (2004) 0.80

Resveratrol attenuates experimental allergic asthma in mice by restoring inositol polyphosphate 4 phosphatase (INPP4A). Int Immunopharmacol (2012) 0.80

Exhaled nitric oxide estimation by a simple and efficient noninvasive technique and its utility as a marker of airway inflammation in mice. J Appl Physiol (1985) (2009) 0.80

Inhaled carbenoxolone prevents allergic airway inflammation and airway hyperreactivity in a mouse model of asthma. Int Arch Allergy Immunol (2008) 0.80

Fish oil regulates cell proliferation, protect DNA damages and decrease HER-2/neu and c-Myc protein expression in rat mammary carcinogenesis. Clin Nutr (2010) 0.80