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1
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Restricting excessive cardiac action potential and QT prolongation: a vital role for IKs in human ventricular muscle.
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Circulation
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2005
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Simulation of the undiseased human cardiac ventricular action potential: model formulation and experimental validation.
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PLoS Comput Biol
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2011
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3.21
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3
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Role of IKur in controlling action potential shape and contractility in the human atrium: influence of chronic atrial fibrillation.
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Circulation
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2004
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1.77
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4
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Functional modulation of the transient outward current Ito by KCNE beta-subunits and regional distribution in human non-failing and failing hearts.
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Cardiovasc Res
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2006
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1.62
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A multiscale investigation of repolarization variability and its role in cardiac arrhythmogenesis.
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Biophys J
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6
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Deranged sodium to sudden death.
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J Physiol
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2015
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7
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Left-to-right atrial inward rectifier potassium current gradients in patients with paroxysmal versus chronic atrial fibrillation.
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Circ Arrhythm Electrophysiol
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2010
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1.49
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8
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A new severe acute necrotizing pancreatitis model induced by L-ornithine in rats.
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Crit Care Med
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2008
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1.48
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9
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Interaction of different potassium channels in cardiac repolarization in dog ventricular preparations: role of repolarization reserve.
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Br J Pharmacol
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2002
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1.44
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10
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Effects of SEA0400 and KB-R7943 on Na+/Ca2+ exchange current and L-type Ca2+ current in canine ventricular cardiomyocytes.
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Naunyn Schmiedebergs Arch Pharmacol
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2005
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11
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Mutations in sodium channel β-subunit SCN3B are associated with early-onset lone atrial fibrillation.
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Cardiovasc Res
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2010
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1.38
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12
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Slow delayed rectifier potassium current (IKs) and the repolarization reserve.
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Ann Noninvasive Electrocardiol
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2007
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1.25
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13
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Does small-conductance calcium-activated potassium channel contribute to cardiac repolarization?
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J Mol Cell Cardiol
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2009
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14
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Systems approach to understanding electromechanical activity in the human heart: a national heart, lung, and blood institute workshop summary.
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Circulation
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2008
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1.17
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15
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Ionic mechanisms limiting cardiac repolarization reserve in humans compared to dogs.
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J Physiol
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2013
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1.17
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16
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Heterogeneous Connexin43 distribution in heart failure is associated with dispersed conduction and enhanced susceptibility to ventricular arrhythmias.
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Eur J Heart Fail
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2010
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1.15
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17
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Mechanisms of ventricular rate adaptation as a predictor of arrhythmic risk.
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Am J Physiol Heart Circ Physiol
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2010
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1.12
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18
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Asymmetrical distribution of ion channels in canine and human left-ventricular wall: epicardium versus midmyocardium.
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Pflugers Arch
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2005
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1.09
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19
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Endocardial versus epicardial differences in L-type calcium current in canine ventricular myocytes studied by action potential voltage clamp.
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Cardiovasc Res
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2003
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1.08
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20
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Role of KATP channels in the maintenance of ventricular fibrillation in cardiomyopathic human hearts.
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Circ Res
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2011
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1.05
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21
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Selective inhibition of sodium-calcium exchanger by SEA-0400 decreases early and delayed after depolarization in canine heart.
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Br J Pharmacol
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2004
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1.03
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22
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Usefulness of short-term variability of QT intervals as a predictor for electrical remodeling and proarrhythmia in patients with nonischemic heart failure.
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Am J Cardiol
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2010
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1.02
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23
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Diabetes mellitus attenuates the repolarization reserve in mammalian heart.
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Cardiovasc Res
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2006
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1.00
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24
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Peroxynitrite-induced alpha-actinin nitration and contractile alterations in isolated human myocardial cells.
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Cardiovasc Res
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2005
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0.96
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25
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Levosimendan interacts with potassium channel blockers in human saphenous veins.
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Basic Clin Pharmacol Toxicol
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2004
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0.96
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26
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Preconditioning effects of levosimendan in a rabbit cardiac ischemia-reperfusion model.
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J Cardiovasc Pharmacol
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2006
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0.95
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27
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Reverse rate dependency is an intrinsic property of canine cardiac preparations.
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Cardiovasc Res
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2009
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0.94
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28
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Activation of the poly(ADP-ribose) polymerase pathway in human heart failure.
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Mol Med
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2006
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29
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New experimental method to study acid/base transporters and their regulation in lacrimal gland ductal epithelia.
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Invest Ophthalmol Vis Sci
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2007
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0.92
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30
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Calpain-1-sensitive myofibrillar proteins of the human myocardium.
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Mol Cell Biochem
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2005
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31
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NEP inhibitors enhance C-type natriuretic peptide-induced relaxation in porcine isolated coronary artery.
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Vascul Pharmacol
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2005
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0.92
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32
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Absolute beat-to-beat variability and instability parameters of ECG intervals: biomarkers for predicting ischaemia-induced ventricular fibrillation.
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Br J Pharmacol
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2014
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33
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Potential therapeutic effects of Na+/Ca2+ exchanger inhibition in cardiac diseases.
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Curr Med Chem
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2009
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34
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Herpesvirus-mediated delivery of a genetically encoded fluorescent Ca(2+) sensor to canine cardiomyocytes.
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J Biomed Biotechnol
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2009
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0.89
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35
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Electrophysiological effects of ivabradine in dog and human cardiac preparations: potential antiarrhythmic actions.
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Eur J Pharmacol
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2011
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0.89
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36
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Gene expression profiling of human cardiac potassium and sodium channels.
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Int J Cardiol
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2005
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37
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Effects of thymol on calcium and potassium currents in canine and human ventricular cardiomyocytes.
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Br J Pharmacol
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2002
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38
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Class I/B antiarrhythmic property of ranolazine, a novel antianginal agent, in dog and human cardiac preparations.
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Eur J Pharmacol
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2011
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0.88
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39
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The role of the Na+/Ca2+ exchanger, I(Na) and I(CaL) in the genesis of dofetilide-induced torsades de pointes in isolated, AV-blocked rabbit hearts.
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Br J Pharmacol
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2009
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0.86
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40
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Self-augmentation of the lengthening of repolarization is related to the shape of the cardiac action potential: implications for reverse rate dependency.
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Br J Pharmacol
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2008
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0.86
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41
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Increased short-term variability of the QT interval in professional soccer players: possible implications for arrhythmia prediction.
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PLoS One
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2011
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0.85
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42
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Protein kinase C mediates the inhibitory effect of substance P on HCO3- secretion from guinea pig pancreatic ducts.
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Am J Physiol Cell Physiol
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2004
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0.85
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43
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Effect of partial blockade of the Na(+)/Ca(2+)-exchanger on Ca(2+) handling in isolated rat ventricular myocytes.
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Eur J Pharmacol
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2007
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0.85
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44
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Reverse rate-dependent changes are determined by baseline action potential duration in mammalian and human ventricular preparations.
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Basic Res Cardiol
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2010
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0.85
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45
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The Na+/Ca2+ exchange blocker SEA0400 fails to enhance cytosolic Ca2+ transient and contractility in canine ventricular cardiomyocytes.
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Cardiovasc Res
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2008
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0.85
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46
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Importance of extracardiac alpha1-adrenoceptor stimulation in assisting dofetilide to induce torsade de pointes in rabbit hearts.
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Eur J Pharmacol
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2006
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0.84
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47
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Effects of terpenoid phenol derivatives on calcium current in canine and human ventricular cardiomyocytes.
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Eur J Pharmacol
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2004
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0.84
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48
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Effect of a neuroprotective drug, eliprodil on cardiac repolarisation: importance of the decreased repolarisation reserve in the development of proarrhythmic risk.
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Br J Pharmacol
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2004
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0.84
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49
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Selective Na(+) /Ca(2+) exchanger inhibition prevents Ca(2+) overload-induced triggered arrhythmias.
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Br J Pharmacol
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2014
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0.84
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50
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[Ca²⁺] i-induced augmentation of the inward rectifier potassium current (IK1) in canine and human ventricular myocardium.
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Pflugers Arch
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2013
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0.82
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51
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Comparison of the effect of class IA antiarrhythmic drugs on transmembrane potassium currents in rabbit ventricular myocytes.
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J Cardiovasc Pharmacol Ther
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2003
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52
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Altered expression of genes for Kir ion channels in dilated cardiomyopathy.
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Can J Physiol Pharmacol
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2013
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53
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SLC26 transporters and the inhibitory control of pancreatic ductal bicarbonate secretion.
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Novartis Found Symp
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2006
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54
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Alternative promoter usage and splicing of the human SCN5A gene contribute to transcript heterogeneity.
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DNA Cell Biol
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2010
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55
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SEA0400 fails to alter the magnitude of intracellular Ca2+ transients and contractions in Langendorff-perfused guinea pig heart.
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Naunyn Schmiedebergs Arch Pharmacol
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2008
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0.79
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56
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Biomarkers and endogenous determinants of dofetilide-induced torsades de pointes in α(1) -adrenoceptor-stimulated, anaesthetized rabbits.
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Br J Pharmacol
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2010
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57
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L-364,373 fails to activate the slow delayed rectifier K+ current in canine ventricular cardiomyocytes.
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Naunyn Schmiedebergs Arch Pharmacol
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2006
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58
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Prolonged antispasmodic effect in isolated radial artery graft and pronounced platelet inhibition induced by the inodilator drug, levosimendan.
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Basic Clin Pharmacol Toxicol
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2011
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59
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Multiple cellular electrophysiological effects of azimilide in canine cardiac preparations.
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Eur J Pharmacol
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2003
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60
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L-364,373 (R-L3) enantiomers have opposite modulating effects on IKs in mammalian ventricular myocytes.
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Can J Physiol Pharmacol
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2013
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61
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[Complementary therapies--based on the principles of evidence-based medicine. Position statement of the Medical Sciences Section of the Hungarian Academy of Sciences].
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Orv Hetil
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2011
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62
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Effect of herpesvirus infection on pancreatic duct cell secretion.
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World J Gastroenterol
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63
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Novel antiarrhythmic compounds with combined class IB and class III mode of action.
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Curr Med Chem
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2004
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0.75
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64
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Diclofenac prolongs repolarization in ventricular muscle with impaired repolarization reserve.
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PLoS One
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2012
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0.75
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65
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Biseko colloidal solution diminishes the vasoreactivity of human isolated radial arteries.
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Eur J Cardiothorac Surg
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2009
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0.75
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66
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Cellular electrophysiological effect of terikalant in the dog heart.
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Eur J Pharmacol
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2005
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67
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Drug-induced changes in action potential duration are proportional to action potential duration in rat ventricular myocardium.
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Gen Physiol Biophys
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2010
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0.75
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68
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Vasorelaxing effect of levosimendan against 5-hydroxytryptamine-induced contractions in isolated human conduit bypass grafts.
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J Pharm Pharmacol
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69
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[Drug therapy of atrial fibrillation].
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Orv Hetil
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Low 4-aminopyridine concentration-induced contraction is mediated by neuronal noradrenaline in canine saphenous vein.
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Vascul Pharmacol
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2002
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0.75
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71
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Assessment of efficacy of proarrhythmia biomarkers in isolated rabbit hearts with attenuated repolarization reserve.
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J Cardiovasc Pharmacol
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2014
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72
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Neurogenic contraction induced by the antiarrhythmic compound, AVE 0118, in rat small mesenteric arteries.
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Basic Clin Pharmacol Toxicol
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2014
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73
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[Non-pharmacologic treatment of atrial fibrillation].
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Orv Hetil
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2003
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Can J Physiol Pharmacol
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2013
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76
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Interspecies differences and extracellular calcium dependence in the vasorelaxing effect of cromakalim in isolated human, porcine, and canine coronary arteries.
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J Cardiovasc Pharmacol Ther
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2010
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77
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The effect of levosimendan during long-term amiodarone treatment in dogs.
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Basic Clin Pharmacol Toxicol
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2006
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