Published in Chem Biol Drug Des on January 19, 2010
Structural basis for the regulation of tubulin by vinblastine. Nature (2005) 3.10
Application of the palladium-catalyzed borylation/Suzuki coupling (BSC) reaction to the synthesis of biologically active biaryl lactams. J Org Chem (2002) 1.12
The palladium-catalyzed C-H activation of benzylic gem-dialkyl groups. Angew Chem Int Ed Engl (2003) 1.09
Discovery of isoerianin analogues as promising anticancer agents. ChemMedChem (2011) 0.96
Synthesis and biological evaluation of (3,4,5-trimethoxyphenyl)indol-3-ylmethane derivatives as potential antivascular agents. Bioorg Med Chem (2006) 0.93
Synthesis of novel macrocyclic docetaxel analogues. Influence of their macrocyclic ring size on tubulin activity. J Med Chem (2003) 0.93
Asymmetric synthesis of an axially chiral antimitotic biaryl via an atropo-enantioselective Suzuki cross-coupling. J Org Chem (2003) 0.91
Kingianin A: a new natural pentacyclic compound from Endiandra kingiana. Org Lett (2010) 0.90
Two novel series of allocolchicinoids with modified seven membered B-rings: design, synthesis, inhibition of tubulin assembly and cytotoxicity. Bioorg Med Chem (2005) 0.90
Synthesis and biological evaluation of A-ring biaryl-carbamate analogues of rhazinilam. Bioorg Med Chem (2002) 0.89
Synthesis of C2-C3'N-linked macrocyclic taxoids. Novel docetaxel analogues with high tubulin activity. J Med Chem (2004) 0.89
Cytotoxic sesquiterpenoids from Winteraceae of Caledonian rainforest. Phytochemistry (2009) 0.88
Synthesis and biological evaluation of B-ring analogues of (-)-rhazinilam. Bioorg Med Chem (2005) 0.87
Alkylated flavanones from the bark of Cryptocarya chartacea as dengue virus NS5 polymerase inhibitors. J Nat Prod (2011) 0.87
New antitubulin derivatives in the combretastatin A4 series: synthesis and biological evaluation. Bioorg Med Chem (2005) 0.86
Eudesmane derivatives and other sesquiterpenes from Laggera alata. J Nat Prod (2003) 0.86
Pentacyclic polyketides from Endiandra kingiana as inhibitors of the Bcl-xL/Bak interaction. Phytochemistry (2011) 0.85
Antiplasmodial benzophenones from the trunk latex of Moronobea coccinea (Clusiaceae). Phytochemistry (2008) 0.85
New C5-alkylated indolobenzazepinones acting as inhibitors of tubulin polymerization: cytotoxic and antitumor activities. J Med Chem (2008) 0.85
Synthesis and antitumor activity of benzils related to combretastatin A-4. Bioorg Med Chem Lett (2008) 0.85
Prostratin and 12-O-tetradecanoylphorbol 13-acetate are potent and selective inhibitors of Chikungunya virus replication. J Nat Prod (2012) 0.84
Biologically active tetralones from New Caledonian Zygogynum spp. Phytochemistry (2008) 0.84
Cytotoxic flavonoids and alpha-pyrones from Cryptocarya obovata. J Nat Prod (2004) 0.83
Antiplasmodial benzophenone derivatives from the root barks of Symphonia globulifera (Clusiaceae). Phytochemistry (2010) 0.83
Antiplasmodial, antitrypanosomal, and cytotoxic activities of prenylated flavonoids isolated from the stem bark of Artocarpus styracifolius. Planta Med (2010) 0.83
Novel C2-C3' N-peptide linked macrocyclic taxoids. Part 2: synthesis and biological activities of docetaxel analogues with a peptide side chain at C2 and their macrocyclic derivatives. Bioorg Med Chem (2006) 0.83
Cytotoxic arylnaphthalene lignans from a Vietnamese acanthaceae, Justicia patentiflora. J Nat Prod (2005) 0.82
Antiviral chlorinated daphnane diterpenoid orthoesters from the bark and wood of Trigonostemon cherrieri. Phytochemistry (2012) 0.82
In vitro oxidative metabolism study of (-)-rhazinilam. Bioorg Med Chem (2005) 0.82
Structure of human glycolate oxidase in complex with the inhibitor 4-carboxy-5-[(4-chlorophenyl)sulfanyl]-1,2,3-thiadiazole. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.82
Regioselective hydrostannation of diarylalkynes directed by a labile ortho bromine atom: an easy access to stereodefined triarylolefins, hybrids of combretastatin A-4 and isocombretastatin A-4. Eur J Med Chem (2010) 0.82
Synthesis, biological evaluation of 1,1-diarylethylenes as a novel class of antimitotic agents. ChemMedChem (2009) 0.81
Chemical constituents of Anacolosa pervilleana and their antiviral activities. Fitoterapia (2012) 0.81
A phenotypic assay to identify Chikungunya virus inhibitors targeting the nonstructural protein nsP2. J Biomol Screen (2012) 0.81
A new xanthone from the bark extract of Rheedia acuminata and antiplasmodial activity of its major compounds. Molecules (2010) 0.80
Synthesis and biological evaluation of a series of tangeretin-derived chalcones. Bioorg Med Chem Lett (2008) 0.80
Cytotoxic prenylated isoflavone and bipterocarpan from Millettia pachyloba. Planta Med (2010) 0.79
Toxicarioside M, a new cytotoxic 10β-hydroxy-19-nor-cardenolide from Antiaris toxicaria. Fitoterapia (2012) 0.79
First BRET-based screening assay performed in budding yeast leads to the discovery of CDK5/p25 interaction inhibitors. Biotechnol J (2011) 0.79
Isocombretastatins a versus combretastatins a: the forgotten isoCA-4 isomer as a highly promising cytotoxic and antitubulin agent. J Med Chem (2009) 0.79
Synthesis and biological evaluation of a new series of highly functionalized 7'-homo-anhydrovinblastine derivatives. J Med Chem (2013) 0.79
Ugandenial A, a new drimane-type sesquiterpenoid from Warburgia ugandensis. Molecules (2009) 0.79
Synthesis and biological evaluation of a natural ester sintenin and its synthetic analogues. J Nat Prod (2005) 0.78
Flacourtosides A-F, phenolic glycosides isolated from Flacourtia ramontchi. J Nat Prod (2012) 0.78
Endiandric acid analogues from Beilschmiedia ferruginea as dual inhibitors of Bcl-xL/Bak and Mcl-1/Bid interactions. J Nat Prod (2014) 0.78
New inhibitors of prion replication that target the amyloid precursor. J Gen Virol (2009) 0.78
Cytotoxic lignans from fruits of Cleistanthus indochinensis: synthesis of cleistantoxin derivatives. J Nat Prod (2012) 0.78
Jatrophane diterpenes as inhibitors of chikungunya virus replication: structure-activity relationship and discovery of a potent lead. J Nat Prod (2014) 0.78
Design, synthesis and antiproliferative activities of biarylolefins based on polyhydroxylated and carbohydrate scaffolds. Eur J Med Chem (2011) 0.78
Trigocherrin A, the first natural chlorinated daphnane diterpene orthoester from Trigonostemon cherrieri. Org Lett (2011) 0.77
Synthesis and biological evaluation of cis-locked vinylogous combretastatin-A4 analogues: derivatives with a cyclopropyl-vinyl or a cyclopropyl-amide bridge. Bioorg Med Chem Lett (2009) 0.77
Cytotoxic pentacyclic triterpenoids from Combretum sundaicum and Lantana camara as inhibitors of Bcl-xL/BakBH3 domain peptide interaction. J Nat Prod (2009) 0.77
Semisynthesis and antiproliferative evaluation of a series of 3'-aminoflavones. Bioorg Med Chem Lett (2009) 0.77
Biaryl axis as a stereochemical relay for the enantioselective synthesis of antimicrotubule agents. Angew Chem Int Ed Engl (2006) 0.77
B-ring-modified isocombretastatin A-4 analogues endowed with interesting anticancer activities. ChemMedChem (2011) 0.77
Natural aristolactams and aporphine alkaloids as inhibitors of CDK1/cyclin B and DYRK1A. Molecules (2013) 0.76
Biomimetic total synthesis of meiogynin A, an inhibitor of Bcl-xL and Bak interaction. J Org Chem (2010) 0.76
Synthesis and tubulin-binding properties of new allocolchicinoids. Bioorg Chem (2010) 0.76
Novel C2-C3' N-peptide linked macrocyclic taxoids. Part 1: Synthesis and biological activities of docetaxel analogues with a peptide side chain at C3'. Bioorg Med Chem Lett (2005) 0.76
Synthesis, biological evaluation, and molecular modeling of natural and unnatural flavonoidal alkaloids, inhibitors of kinases. J Med Chem (2012) 0.76
Potent antiproliferative cembrenoids accumulate in tobacco upon infection with Rhodococcus fascians and trigger unusual microtubule dynamics in human glioblastoma cells. PLoS One (2013) 0.75
A Dimeric sesquiterpenoid from a Malaysian Meiogyne as a new inhibitor of Bcl-xL/BakBH3 domain peptide interaction. J Nat Prod (2009) 0.75
An in silico approach for the discovery of CDK5/p25 interaction inhibitors. Biotechnol J (2011) 0.75
Direct and selective functionalization of a tetrahydro-beta-carboline at position 4. Org Lett (2010) 0.75
Cytotoxic farnesyl glycosides from Pittosporum pancheri. Phytochemistry (2006) 0.75
Synthesis and cytotoxicity of racemic isodeoxypodophyllotoxin analogues with isoprene-derived side chains. J Nat Prod (2006) 0.75
Semisynthesis and biological evaluation of a novel D-seco docetaxel analogue. Org Lett (2006) 0.75
Cytotoxic monotetrahydrofuran acetogenins from Disepalum plagioneurum. J Nat Prod (2006) 0.75
Chiral phosphoric acid catalyzed enantioselective transfer hydrogenation of ortho-hydroxybenzophenone N-H ketimines and applications. Chemistry (2011) 0.75
Rearranged diterpenoids from the biotransformation of ent-trachyloban-18-oic acid by Rhizopus arrhizus. J Nat Prod (2010) 0.75
Acylphenols from Myristica crassa as new acetylcholinesterase inhibitors. Planta Med (2008) 0.75
Gas-phase reactivity of acylphenols in electrospray and matrix-assisted laser desorption ionization mass spectrometry. Eur J Mass Spectrom (Chichester, Eng) (2009) 0.75
Synthesis of polysubstituted benzofuran derivatives as novel inhibitors of parasitic growth. Bioorg Med Chem (2013) 0.75
Influence of the skeleton on the cytotoxicity of flavonoids. Bioorg Med Chem (2011) 0.75
Chiral phosphoric acid-catalyzed enantioselective transfer hydrogenation of ortho-hydroxyaryl alkyl N-H ketimines. Org Lett (2010) 0.75
Antiplasmodial alkaloids from Desmos rostrata. J Nat Prod (2008) 0.75
Synthesis of anti-microtubule biaryls and preliminary evaluation as vascular-disrupting agents. ChemMedChem (2008) 0.75
Semisynthesis of natural flavones inhibiting tubulin polymerization, from hesperidin. J Nat Prod (2010) 0.75
Elaboration of vinblastine hybrids using a reactive in situ generated N-carboxyanhydride. Org Biomol Chem (2011) 0.75
Synthesis and biological evaluation of vinca alkaloids and phomopsin hybrids. J Med Chem (2009) 0.75
Goniomedines A and B: unprecedented bisindole alkaloids formed through fusion of two indole moieties via a dihydropyran unit. Org Lett (2012) 0.75
Cytotoxic steroidal alkaloids from Kibatalia laurifolia. J Nat Prod (2011) 0.75
Cytotoxic turrianes of Kermadecia elliptica from the New Caledonian rainforest. Phytochemistry (2007) 0.75
One-pot synthesis of vinca alkaloids-phomopsin hybrids. J Med Chem (2014) 0.75
Synthesis and biological evaluation of novel heterocyclic derivatives of combretastatin A-4. Bioorg Med Chem Lett (2012) 0.75
Synthesis of novel 7-oxo and 7-hydroxy trifluoroallocolchicinoids with cytotoxic effect. Bioorg Med Chem (2012) 0.75
Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk. Bioorg Med Chem (2010) 0.75