X-ray structure and mutational analysis of the atrazine Chlorohydrolase TrzN.

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300-Fold increase in production of the Zn2+-dependent dechlorinase TrzN in soluble form via apoenzyme stabilization. Appl Environ Microbiol (2014) 0.80

Aerobic biodegradation of 2,4-Dinitroanisole by Nocardioides sp. strain JS1661. Appl Environ Microbiol (2014) 0.78

The structure of the hexameric atrazine chlorohydrolase AtzA. Acta Crystallogr D Biol Crystallogr (2015) 0.77

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The atzABC genes encoding atrazine catabolism are located on a self-transmissible plasmid in Pseudomonas sp. strain ADP. Appl Environ Microbiol (1998) 1.14

Crystal structures of native and inactivated cis-3-chloroacrylic acid dehalogenase. Structural basis for substrate specificity and inactivation by (R)-oxirane-2-carboxylate. J Biol Chem (2006) 1.12

Substrate specificity of atrazine chlorohydrolase and atrazine-catabolizing bacteria. Appl Environ Microbiol (2000) 1.11

Evolution of catabolic pathways: Genomic insights into microbial s-triazine metabolism. J Bacteriol (2006) 1.09

Rapid evolution of bacterial catabolic enzymes: a case study with atrazine chlorohydrolase. Biochemistry (2001) 1.09

Structure and mechanism of bacterial dehalogenases: different ways to cleave a carbon-halogen bond. Curr Opin Struct Biol (2003) 1.08

Atrazine chlorohydrolase from Pseudomonas sp. strain ADP is a metalloenzyme. Biochemistry (2002) 1.03

TrzN from Arthrobacter aurescens TC1 Is a zinc amidohydrolase. J Bacteriol (2006) 1.03

Isolation and characterisation of Nocardioides sp. SP12, an atrazine-degrading bacterial strain possessing the gene trzN from bulk- and maize rhizosphere soil. FEMS Microbiol Lett (2003) 1.00

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Substrate specificity and colorimetric assay for recombinant TrzN derived from Arthrobacter aurescens TC1. Appl Environ Microbiol (2005) 0.98

Field-scale remediation of atrazine-contaminated soil using recombinant Escherichia coli expressing atrazine chlorohydrolase. Environ Microbiol (2000) 0.97

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Catalytic improvement and evolution of atrazine chlorohydrolase. Appl Environ Microbiol (2009) 0.87

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Organization of an efficient carbonic anhydrase: implications for the mechanism based on structure-function studies of a T199P/C206S mutant. Biochemistry (2002) 0.86

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C and N isotope fractionation suggests similar mechanisms of microbial atrazine transformation despite involvement of different enzymes (AtzA and TrzN). Environ Sci Technol (2009) 0.77

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Changes in the composition of the human fecal microbiome after bacteriotherapy for recurrent Clostridium difficile-associated diarrhea. J Clin Gastroenterol (2010) 4.52

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Standardized frozen preparation for transplantation of fecal microbiota for recurrent Clostridium difficile infection. Am J Gastroenterol (2012) 3.84

Structure-based activity prediction for an enzyme of unknown function. Nature (2007) 3.65

The University of Minnesota Biocatalysis/Biodegradation Database: the first decade. Nucleic Acids Res (2006) 2.52

Prediction and assignment of function for a divergent N-succinyl amino acid racemase. Nat Chem Biol (2007) 2.29

Presence and growth of naturalized Escherichia coli in temperate soils from Lake Superior watersheds. Appl Environ Microbiol (2006) 2.28

Evolution of enzymatic activities in the enolase superfamily: L-fuconate dehydratase from Xanthomonas campestris. Biochemistry (2006) 2.15

Programmed death-1 (PD-1)-deficient mice are extraordinarily sensitive to tuberculosis. Proc Natl Acad Sci U S A (2010) 2.12

T cell immunoglobulin mucin-3 crystal structure reveals a galectin-9-independent ligand-binding surface. Immunity (2007) 1.92

Structural genomics: a pipeline for providing structures for the biologist. Protein Sci (2002) 1.91

Discovery of a dipeptide epimerase enzymatic function guided by homology modeling and virtual screening. Structure (2008) 1.91

The Enzyme Function Initiative. Biochemistry (2011) 1.87

High-throughput DNA sequence analysis reveals stable engraftment of gut microbiota following transplantation of previously frozen fecal bacteria. Gut Microbes (2013) 1.85

Crystallographic comparison of manganese- and iron-dependent homoprotocatechuate 2,3-dioxygenases. J Bacteriol (2004) 1.84

Structure of the actin crosslinking core of fimbrin. Structure (2004) 1.82

Population structure, persistence, and seasonality of autochthonous Escherichia coli in temperate, coastal forest soil from a Great Lakes watershed. Environ Microbiol (2006) 1.77

Escherichia coli in the Environment: Implications for Water Quality and Human Health. Microbes Environ (2008) 1.76

Secrets of soil survival revealed by the genome sequence of Arthrobacter aurescens TC1. PLoS Genet (2006) 1.76

Regulation of myosin-IIA assembly and Mts1 binding by heavy chain phosphorylation. Biochemistry (2005) 1.73

Structural basis for the coevolution of a viral RNA-protein complex. Nat Struct Mol Biol (2007) 1.71

How radiation kills cells: survival of Deinococcus radiodurans and Shewanella oneidensis under oxidative stress. FEMS Microbiol Rev (2005) 1.70

Structural and functional analysis of the costimulatory receptor programmed death-1. Immunity (2004) 1.70

ZBP1 recognition of beta-actin zipcode induces RNA looping. Genes Dev (2010) 1.63

Sample size, library composition, and genotypic diversity among natural populations of Escherichia coli from different animals influence accuracy of determining sources of fecal pollution. Appl Environ Microbiol (2004) 1.60

Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2. Proc Natl Acad Sci U S A (2008) 1.55

Neighboring group participation in the transition state of human purine nucleoside phosphorylase. Biochemistry (2007) 1.53

Microbiota transplantation restores normal fecal bile acid composition in recurrent Clostridium difficile infection. Am J Physiol Gastrointest Liver Physiol (2013) 1.52

Structural effects of cofilin on longitudinal contacts in F-actin. J Mol Biol (2002) 1.50

Functional classification of immune regulatory proteins. Structure (2013) 1.49

Functional annotation and three-dimensional structure of Dr0930 from Deinococcus radiodurans, a close relative of phosphotriesterase in the amidohydrolase superfamily. Biochemistry (2009) 1.47

Discovery of new enzymes and metabolic pathways by using structure and genome context. Nature (2013) 1.46

Whole-genome nucleotide diversity, recombination, and linkage disequilibrium in the model legume Medicago truncatula. Proc Natl Acad Sci U S A (2011) 1.46

The PD-1/PD-L costimulatory pathway critically affects host resistance to the pathogenic fungus Histoplasma capsulatum. Proc Natl Acad Sci U S A (2008) 1.44

Encoding microbial metabolic logic: predicting biodegradation. J Ind Microbiol Biotechnol (2004) 1.44

Identification of functional residues on Caenorhabditis elegans actin-interacting protein 1 (UNC-78) for disassembly of actin depolymerizing factor/cofilin-bound actin filaments. J Biol Chem (2004) 1.40

Structural underpinnings of nitrogen regulation by the prototypical nitrogen-responsive transcriptional factor NrpR. Structure (2010) 1.40

Divergent evolution in enolase superfamily: strategies for assigning functions. J Biol Chem (2011) 1.40

Structural characterization of acylimine-containing blue and red chromophores in mTagBFP and TagRFP fluorescent proteins. Chem Biol (2010) 1.40

Transition state analogs of 5'-methylthioadenosine nucleosidase disrupt quorum sensing. Nat Chem Biol (2009) 1.39

Microbial pathway prediction: a functional group approach. J Chem Inf Comput Sci (2003) 1.39

Frequency and distribution of tetracycline resistance genes in genetically diverse, nonselected, and nonclinical Escherichia coli strains isolated from diverse human and animal sources. Appl Environ Microbiol (2004) 1.36

Picomolar transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase and X-ray structure with MT-immucillin-A. Biochemistry (2004) 1.35

Mapping the G-actin binding surface of cofilin using synchrotron protein footprinting. Biochemistry (2002) 1.33

Metabolism of thioamides by Ralstonia pickettii TA. Appl Environ Microbiol (2006) 1.31

Growth and survival of Escherichia coli and enterococci populations in the macro-alga Cladophora (Chlorophyta). FEMS Microbiol Ecol (2003) 1.30

Beach sand and sediments are temporal sinks and sources of Escherichia coli in Lake Superior. Environ Sci Technol (2007) 1.30

On the origins of cyanuric acid hydrolase: purification, substrates, and prevalence of AtzD from Pseudomonas sp. strain ADP. Appl Environ Microbiol (2003) 1.30

The University of Minnesota Biocatalysis/Biodegradation Database: post-genomic data mining. Nucleic Acids Res (2003) 1.29

Transcriptional and physiological responses of Bradyrhizobium japonicum to desiccation-induced stress. J Bacteriol (2007) 1.29

Crystal structure of PTP1B complexed with a potent and selective bidentate inhibitor. J Biol Chem (2003) 1.29

Structure and dynamics of the actin filament. Biochemistry (2005) 1.28

Arthrobacter aurescens TC1 metabolizes diverse s-triazine ring compounds. Appl Environ Microbiol (2002) 1.28

Four generations of transition-state analogues for human purine nucleoside phosphorylase. Proc Natl Acad Sci U S A (2010) 1.28

NTB-A receptor crystal structure: insights into homophilic interactions in the signaling lymphocytic activation molecule receptor family. Immunity (2006) 1.27

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Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: evidence for substrate destabilization. Biochemistry (2009) 1.27

Purification and characterization of OleA from Xanthomonas campestris and demonstration of a non-decarboxylative Claisen condensation reaction. J Biol Chem (2011) 1.26

Spatial arrangement of an RNA zipcode identifies mRNAs under post-transcriptional control. Genes Dev (2012) 1.26

B7-1 and B7-2: similar costimulatory ligands with different biochemical, oligomeric and signaling properties. Immunol Lett (2005) 1.24

The University of Minnesota pathway prediction system: predicting metabolic logic. Nucleic Acids Res (2008) 1.24

Cofilin (ADF) affects lateral contacts in F-actin. J Mol Biol (2004) 1.24

The University of Minnesota Biocatalysis/Biodegradation Database: improving public access. Nucleic Acids Res (2009) 1.24

Evaluating pesticide degradation in the environment: blind spots and emerging opportunities. Science (2013) 1.23

Structure and biochemical properties of PRL-1, a phosphatase implicated in cell growth, differentiation, and tumor invasion. Biochemistry (2005) 1.23

Relationship between phylogenetic groups, genotypic clusters, and virulence gene profiles of Escherichia coli strains from diverse human and animal sources. Appl Environ Microbiol (2007) 1.22

Purification, substrate range, and metal center of AtzC: the N-isopropylammelide aminohydrolase involved in bacterial atrazine metabolism. J Bacteriol (2002) 1.22

Widespread head-to-head hydrocarbon biosynthesis in bacteria and role of OleA. Appl Environ Microbiol (2010) 1.22

At the periphery of the amidohydrolase superfamily: Bh0493 from Bacillus halodurans catalyzes the isomerization of D-galacturonate to D-tagaturonate. Biochemistry (2008) 1.22

Structure-guided discovery of the metabolite carboxy-SAM that modulates tRNA function. Nature (2013) 1.22

Structural mechanisms of costimulation. Nat Immunol (2002) 1.21

Genomes of the symbiotic nitrogen-fixing bacteria of legumes. Plant Physiol (2007) 1.20

Structural biology of cellular machines. Trends Cell Biol (2006) 1.19

S100A4 regulates macrophage chemotaxis. Mol Biol Cell (2010) 1.19

Comparative genomics of the core and accessory genomes of 48 Sinorhizobium strains comprising five genospecies. Genome Biol (2013) 1.18

Visualizing the Ca2+-dependent activation of gelsolin by using synchrotron footprinting. Proc Natl Acad Sci U S A (2003) 1.18

Cas5d processes pre-crRNA and is a member of a larger family of CRISPR RNA endonucleases. RNA (2012) 1.18

Photoactivation mechanism of PAmCherry based on crystal structures of the protein in the dark and fluorescent states. Proc Natl Acad Sci U S A (2009) 1.18

Radiation-induced site-specific damage of mercury derivatives: phasing and implications. Acta Crystallogr D Biol Crystallogr (2005) 1.18

A high-affinity interaction with ADP-actin monomers underlies the mechanism and in vivo function of Srv2/cyclase-associated protein. Mol Biol Cell (2004) 1.18

Structural analysis of gelsolin using synchrotron protein footprinting. Mol Cell Proteomics (2003) 1.18