Published in Protein Sci on September 01, 2010
Site-specific and redox-controlled S-nitrosation of thioredoxin. Proc Natl Acad Sci U S A (2011) 1.01
Reactivity of thioredoxin as a protein thiol-disulfide oxidoreductase. Chem Rev (2011) 0.86
Contribution of Fdh3 and Glr1 to Glutathione Redox State, Stress Adaptation and Virulence in Candida albicans. PLoS One (2015) 0.80
Modulation of signaling mechanisms in the heart by thioredoxin 1. Free Radic Biol Med (2016) 0.75
Binding of phenothiazines into allosteric hydrophobic pocket of human thioredoxin 1. Eur Biophys J (2016) 0.75
Structures of the reduced and oxidized state of the mutant D24A of yeast thioredoxin 1: insights into the mechanism for the closing of the water cavity. J Biomol NMR (2015) 0.75
Coot: model-building tools for molecular graphics. Acta Crystallogr D Biol Crystallogr (2004) 227.01
The CCP4 suite: programs for protein crystallography. Acta Crystallogr D Biol Crystallogr (1994) 187.88
Inference of macromolecular assemblies from crystalline state. J Mol Biol (2007) 44.95
Regulated protein denitrosylation by cytosolic and mitochondrial thioredoxins. Science (2008) 4.51
Thioredoxin catalyzes the S-nitrosation of the caspase-3 active site cysteine. Nat Chem Biol (2005) 2.60
Protein denitrosylation: enzymatic mechanisms and cellular functions. Nat Rev Mol Cell Biol (2009) 2.42
Redox-directed cancer therapeutics: molecular mechanisms and opportunities. Antioxid Redox Signal (2009) 2.33
Probing the chemistry of thioredoxin catalysis with force. Nature (2007) 2.17
Redox potential of human thioredoxin 1 and identification of a second dithiol/disulfide motif. J Biol Chem (2003) 2.14
Crystal structures of reduced, oxidized, and mutated human thioredoxins: evidence for a regulatory homodimer. Structure (1996) 2.07
Redox regulatory and anti-apoptotic functions of thioredoxin depend on S-nitrosylation at cysteine 69. Nat Cell Biol (2002) 1.94
Thioredoxins and glutaredoxins as facilitators of protein folding. Biochim Biophys Acta (2008) 1.85
Properties and biological activities of thioredoxins. Annu Rev Pharmacol Toxicol (2001) 1.76
Cardioprotective effects of thioredoxin in myocardial ischemia and reperfusion: role of S-nitrosation [corrected]. Proc Natl Acad Sci U S A (2004) 1.76
Structure, function, and mechanism of thioredoxin proteins. Antioxid Redox Signal (2010) 1.61
The solution structure of human thioredoxin complexed with its target from Ref-1 reveals peptide chain reversal. Structure (1996) 1.58
Solution structure of human thioredoxin in a mixed disulfide intermediate complex with its target peptide from the transcription factor NF kappa B. Structure (1995) 1.53
Thioredoxin is required for S-nitrosation of procaspase-3 and the inhibition of apoptosis in Jurkat cells. Proc Natl Acad Sci U S A (2007) 1.52
Regulation of the catalytic activity and structure of human thioredoxin 1 via oxidation and S-nitrosylation of cysteine residues. J Biol Chem (2008) 1.32
S-nitrosylation: an emerging redox-based post-translational modification in plants. J Exp Bot (2006) 1.12
Diversity of chemical mechanisms in thioredoxin catalysis revealed by single-molecule force spectroscopy. Nat Struct Mol Biol (2009) 1.11
Human thioredoxin homodimers: regulation by pH, role of aspartate 60, and crystal structure of the aspartate 60 --> asparagine mutant. Biochemistry (1997) 1.10
A strategy for direct identification of protein S-nitrosylation sites by quadrupole time-of-flight mass spectrometry. J Am Soc Mass Spectrom (2008) 1.09
Buried S-nitrosocysteine revealed in crystal structures of human thioredoxin. Biochemistry (2007) 1.07
Structural basis for target protein recognition by the protein disulfide reductase thioredoxin. Structure (2006) 1.03
3'-Phosphoadenosine-5'-phosphosulfate reductase in complex with thioredoxin: a structural snapshot in the catalytic cycle. Biochemistry (2007) 0.96
Redox regulation of actin by thioredoxin-1 is mediated by the interaction of the proteins via cysteine 62. Antioxid Redox Signal (2010) 0.89
Suppression of thioredoxin-1 induces premature senescence in normal human fibroblasts. Biochem Biophys Res Commun (2010) 0.88
Thioredoxin-1 and endothelial cell aging: role in cardiovascular diseases. Antioxid Redox Signal (2009) 0.88
Is human thioredoxin monomeric or dimeric? Protein Sci (1999) 0.84
Structure of human thioredoxin exhibits a large conformational change. Protein Sci (2010) 0.78
Redox potential of human thioredoxin 1 and identification of a second dithiol/disulfide motif. J Biol Chem (2003) 2.14
Crystal structure and electron transfer kinetics of CueO, a multicopper oxidase required for copper homeostasis in Escherichia coli. Proc Natl Acad Sci U S A (2002) 1.86
Transitive homology-guided structural studies lead to discovery of Cro proteins with 40% sequence identity but different folds. Proc Natl Acad Sci U S A (2008) 1.59
A novel copper-binding fold for the periplasmic copper resistance protein CusF. Biochemistry (2005) 1.52
Heme-assisted S-nitrosation of a proximal thiolate in a nitric oxide transport protein. Proc Natl Acad Sci U S A (2005) 1.52
Cuprous oxidase activity of CueO from Escherichia coli. J Bacteriol (2004) 1.39
A labile regulatory copper ion lies near the T1 copper site in the multicopper oxidase CueO. J Biol Chem (2003) 1.35
Ultrahigh resolution structures of nitrophorin 4: heme distortion in ferrous CO and NO complexes. Biochemistry (2005) 1.25
NM23-H2 may play an indirect role in transcriptional activation of c-myc gene expression but does not cleave the nuclease hypersensitive element III(1). Mol Cancer Ther (2009) 1.19
Role of binding site loops in controlling nitric oxide release: structure and kinetics of mutant forms of nitrophorin 4. Biochemistry (2004) 1.16
X-ray structure of Cerulean GFP: a tryptophan-based chromophore useful for fluorescence lifetime imaging. Biochemistry (2007) 1.08
Buried S-nitrosocysteine revealed in crystal structures of human thioredoxin. Biochemistry (2007) 1.07
Protein functional cycle viewed at atomic resolution: conformational change and mobility in nitrophorin 4 as a function of pH and NO binding. Biochemistry (2004) 1.04
Rational reprogramming of fungal polyketide first-ring cyclization. Proc Natl Acad Sci U S A (2013) 1.02
S-nitrosylation-induced conformational change in blackfin tuna myoglobin. J Biol Chem (2007) 1.01
Allostery in recombinant soluble guanylyl cyclase from Manduca sexta. J Biol Chem (2008) 1.01
Axial ligand complexes of the Rhodnius nitrophorins: reduction potentials, binding constants, EPR spectra, and structures of the 4-iodopyrazole and imidazole complexes of NP4. J Biol Inorg Chem (2003) 1.01
Molecular model of a soluble guanylyl cyclase fragment determined by small-angle X-ray scattering and chemical cross-linking. Biochemistry (2013) 0.99
Low-frequency mode activity of heme: femtosecond coherence spectroscopy of iron porphine halides and nitrophorin. J Am Chem Soc (2008) 0.97
Crystal structures of multicopper oxidase CueO bound to copper(I) and silver(I): functional role of a methionine-rich sequence. J Biol Chem (2011) 0.97
Structural dynamics controls nitric oxide affinity in nitrophorin 4. J Biol Chem (2004) 0.96
Assignment of the ferriheme resonances of the low-spin complexes of nitrophorins 1 and 4 by (1)H and (13)C NMR spectroscopy: comparison to structural data obtained from X-ray crystallography. Inorg Chem (2007) 0.95
Crystal structure of the bacterial luciferase/flavin complex provides insight into the function of the beta subunit. Biochemistry (2009) 0.95
Oxidation and loss of heme in soluble guanylyl cyclase from Manduca sexta. Biochemistry (2011) 0.94
Ultrafast dynamics of diatomic ligand binding to nitrophorin 4. J Am Chem Soc (2010) 0.93
Effect of mutation of carboxyl side-chain amino acids near the heme on the midpoint potentials and ligand binding constants of nitrophorin 2 and its NO, histamine, and imidazole complexes. J Am Chem Soc (2009) 0.91
Binding of YC-1 or BAY 41-2272 to soluble guanylyl cyclase induces a geminate phase in CO photolysis. J Am Chem Soc (2008) 0.90
Crystal structure of the Alpha subunit PAS domain from soluble guanylyl cyclase. Protein Sci (2013) 0.90
Thrombospondin-1 and angiotensin II inhibit soluble guanylyl cyclase through an increase in intracellular calcium concentration. Biochemistry (2011) 0.89
Nonequilibrium dynamics simulations of nitric oxide release: comparative study of nitrophorin and myoglobin. J Phys Chem B (2007) 0.87
IgE against bed bug (Cimex lectularius) allergens is common among adults bitten by bed bugs. J Allergy Clin Immunol (2012) 0.87
YC-1 binding to the β subunit of soluble guanylyl cyclase overcomes allosteric inhibition by the α subunit. Biochemistry (2013) 0.85
N15 Cro and lambda Cro: orthologous DNA-binding domains with completely different but equally effective homodimer interfaces. Protein Sci (2008) 0.83
Structure of the Y94F mutant of Escherichia coli thymidylate synthase. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.82
Crystal structures of thymidylate synthase mutant R166Q: structural basis for the nearly complete loss of catalytic activity. J Biochem Mol Toxicol (2006) 0.81
Apo-nitrophorin 4 at atomic resolution. Protein Sci (2007) 0.78
pH-dependent picosecond structural dynamics in the distal pocket of nitrophorin 4 investigated by 2D IR spectroscopy. J Phys Chem B (2013) 0.77
5,10-Methylene-5,6,7,8-tetrahydrofolate conformational transitions upon binding to thymidylate synthase: molecular mechanics and continuum solvent studies. J Comput Aided Mol Des (2005) 0.77
Role of an invariant lysine residue in folate binding on Escherichia coli thymidylate synthase: calorimetric and crystallographic analysis of the K48Q mutant. Int J Biochem Cell Biol (2008) 0.77
A new use for a familiar fold: the X-ray crystal structure of GTP-bound GTP cyclohydrolase III from Methanocaldococcus jannaschii reveals a two metal ion catalytic mechanism. Biochemistry (2007) 0.76
Dimerization of nitrophorin 4 at low pH and comparison to the K1A mutant of nitrophorin 1. Biochemistry (2014) 0.75
Complementing thymidylate synthase. Structure (2003) 0.75