Inference of macromolecular assemblies from crystalline state.

Overview of the CCP4 suite and current developments. Acta Crystallogr D Biol Crystallogr (2011) 67.55

Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing. Science (2011) 7.92

The RCSB Protein Data Bank: redesigned web site and web services. Nucleic Acids Res (2010) 7.68

Presenting your structures: the CCP4mg molecular-graphics software. Acta Crystallogr D Biol Crystallogr (2011) 6.27

Implications for kinetochore-microtubule attachment from the structure of an engineered Ndc80 complex. Cell (2008) 5.87

Broad and potent neutralization of HIV-1 by a gp41-specific human antibody. Nature (2012) 5.44

Protein structure homology modeling using SWISS-MODEL workspace. Nat Protoc (2009) 5.42

Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus. Nature (2013) 5.35

Toward the estimation of the absolute quality of individual protein structure models. Bioinformatics (2010) 5.08

Structural basis of Wnt recognition by Frizzled. Science (2012) 4.31

The RCSB Protein Data Bank: views of structural biology for basic and applied research and education. Nucleic Acids Res (2014) 3.57

Rational HIV immunogen design to target specific germline B cell receptors. Science (2013) 3.55

PDBe: Protein Data Bank in Europe. Nucleic Acids Res (2009) 3.48

Structure-based prediction of protein-protein interactions on a genome-wide scale. Nature (2012) 3.37

PDBe: Protein Data Bank in Europe. Nucleic Acids Res (2011) 3.03

Structures of asymmetric ClpX hexamers reveal nucleotide-dependent motions in a AAA+ protein-unfolding machine. Cell (2009) 2.87

Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis. Nature (2012) 2.86

Plant UVR8 photoreceptor senses UV-B by tryptophan-mediated disruption of cross-dimer salt bridges. Science (2012) 2.80

The structure of an integrin/talin complex reveals the basis of inside-out signal transduction. EMBO J (2009) 2.76

Structural basis of the 9-fold symmetry of centrioles. Cell (2011) 2.73

Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans. PLoS Pathog (2013) 2.66

Structural analysis of the STING adaptor protein reveals a hydrophobic dimer interface and mode of cyclic di-GMP binding. Immunity (2012) 2.47

A large-scale conformational change couples membrane recruitment to cargo binding in the AP2 clathrin adaptor complex. Cell (2010) 2.35

Computational design of self-assembling protein nanomaterials with atomic level accuracy. Science (2012) 2.33

Architecture of the Atg17 complex as a scaffold for autophagosome biogenesis. Cell (2012) 2.30

OPM database and PPM web server: resources for positioning of proteins in membranes. Nucleic Acids Res (2011) 2.28

SDM--a server for predicting effects of mutations on protein stability and malfunction. Nucleic Acids Res (2011) 2.28

Crystal structure of a human GABAA receptor. Nature (2014) 2.22

PDBe: Protein Data Bank in Europe. Nucleic Acids Res (2013) 2.16

MMDB: 3D structures and macromolecular interactions. Nucleic Acids Res (2011) 2.06

Crystal structure of oligomeric β1-adrenergic G protein-coupled receptors in ligand-free basal state. Nat Struct Mol Biol (2013) 2.06

The structural basis for the sensing and binding of cyclic di-GMP by STING. Nat Struct Mol Biol (2012) 2.04

How Quorum Sensing Connects Sporulation to Necrotrophism in Bacillus thuringiensis. PLoS Pathog (2016) 2.04

Antibody 8ANC195 reveals a site of broad vulnerability on the HIV-1 envelope spike. Cell Rep (2014) 2.01

Sorting of the Alzheimer's disease amyloid precursor protein mediated by the AP-4 complex. Dev Cell (2010) 1.98

AlgK is a TPR-containing protein and the periplasmic component of a novel exopolysaccharide secretin. Structure (2010) 1.97

The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis. Nature (2012) 1.97

Phosphorylation in protein-protein binding: effect on stability and function. Structure (2011) 1.96

PAAR-repeat proteins sharpen and diversify the type VI secretion system spike. Nature (2013) 1.96

Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function. Protein Sci (2010) 1.95

Structural basis for c-di-GMP-mediated inside-out signaling controlling periplasmic proteolysis. PLoS Biol (2011) 1.93

Structural basis for light-dependent signaling in the dimeric LOV domain of the photosensor YtvA. J Mol Biol (2007) 1.90

Structural basis of respiratory syncytial virus neutralization by motavizumab. Nat Struct Mol Biol (2010) 1.89

PDBe: Protein Data Bank in Europe. Nucleic Acids Res (2010) 1.88

Structural profiling of endogenous S-nitrosocysteine residues reveals unique features that accommodate diverse mechanisms for protein S-nitrosylation. Proc Natl Acad Sci U S A (2010) 1.87

Insights into the evolution of a complex virus from the crystal structure of vaccinia virus D13. Structure (2011) 1.86

CENP-T-W-S-X forms a unique centromeric chromatin structure with a histone-like fold. Cell (2012) 1.85

Inferred Biomolecular Interaction Server--a web server to analyze and predict protein interacting partners and binding sites. Nucleic Acids Res (2009) 1.85

The structure of a cytolytic alpha-helical toxin pore reveals its assembly mechanism. Nature (2009) 1.84

Assignment of protein sequences to existing domain and family classification systems: Pfam and the PDB. Bioinformatics (2012) 1.82

Crystal structure of the FeS cluster-containing nucleotide excision repair helicase XPD. PLoS Biol (2008) 1.81

Structural basis of substrate discrimination and integrin binding by autotaxin. Nat Struct Mol Biol (2011) 1.81

Mechanism of actin filament nucleation by the bacterial effector VopL. Nat Struct Mol Biol (2011) 1.80

Structural analysis of the GGDEF-EAL domain-containing c-di-GMP receptor FimX. Structure (2009) 1.79

Crystal structure of the yeast vacuolar ATPase heterotrimeric EGC(head) peripheral stalk complex. Structure (2012) 1.79

Molecular basis for shared cytokine recognition revealed in the structure of an unusually high affinity complex between IL-13 and IL-13Ralpha2. Structure (2010) 1.79

MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res (2013) 1.79

Structure of the vesicular stomatitis virus nucleocapsid in complex with the nucleocapsid-binding domain of the small polymerase cofactor, P. Proc Natl Acad Sci U S A (2009) 1.78

Structural insight into the essential PB1-PB2 subunit contact of the influenza virus RNA polymerase. EMBO J (2009) 1.78

Malaria parasite CelTOS targets the inner leaflet of cell membranes for pore-dependent disruption. Elife (2016) 1.76

Tetrameric c-di-GMP mediates effective transcription factor dimerization to control Streptomyces development. Cell (2014) 1.74

Three-dimensional structure of a viral genome-delivery portal vertex. Nat Struct Mol Biol (2011) 1.71

Atomic structures of a bactericidal contractile nanotube in its pre- and postcontraction states. Nat Struct Mol Biol (2015) 1.70

Structure of the Notch1-negative regulatory region: implications for normal activation and pathogenic signaling in T-ALL. Blood (2008) 1.69

Dissecting protein-RNA recognition sites. Nucleic Acids Res (2008) 1.67

Dissecting heterogeneous molecular chaperone complexes using a mass spectrum deconvolution approach. Chem Biol (2012) 1.66

The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM. Cell (2011) 1.66

Crystal structure of the APOBEC3G catalytic domain reveals potential oligomerization interfaces. Structure (2010) 1.65

Drug resistance against HCV NS3/4A inhibitors is defined by the balance of substrate recognition versus inhibitor binding. Proc Natl Acad Sci U S A (2010) 1.65

The 2.8 Å crystal structure of the dynein motor domain. Nature (2012) 1.65

Structure of the large ribosomal subunit from human mitochondria. Science (2014) 1.64

A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore. Nat Chem Biol (2014) 1.64

Structural basis of recognition of interferon-α receptor by tyrosine kinase 2. Nat Struct Mol Biol (2014) 1.64

Structural insights into tail-anchored protein binding and membrane insertion by Get3. Proc Natl Acad Sci U S A (2009) 1.63

The crystal structure of an oxygen-tolerant hydrogenase uncovers a novel iron-sulphur centre. Nature (2011) 1.63

ZBP1 recognition of beta-actin zipcode induces RNA looping. Genes Dev (2010) 1.63

Structure of the GLD-1 homodimerization domain: insights into STAR protein-mediated translational regulation. Structure (2010) 1.62

Crystal structure of group II chaperonin in the open state. Structure (2010) 1.62

Structure of the F-actin-tropomyosin complex. Nature (2014) 1.61

A recurring motif for antibody recognition of the receptor-binding site of influenza hemagglutinin. Nat Struct Mol Biol (2013) 1.60

Structure of PlcR: Insights into virulence regulation and evolution of quorum sensing in Gram-positive bacteria. Proc Natl Acad Sci U S A (2007) 1.60

Protein painting reveals solvent-excluded drug targets hidden within native protein-protein interfaces. Nat Commun (2014) 1.59

Mechanism of ubiquitylation by dimeric RING ligase RNF4. Nat Struct Mol Biol (2011) 1.59

Model for eukaryotic tail-anchored protein binding based on the structure of Get3. Proc Natl Acad Sci U S A (2009) 1.59

Structural basis of semaphorin-plexin signalling. Nature (2010) 1.58

Molecular basis for the association of human E4B U box ubiquitin ligase with E2-conjugating enzymes UbcH5c and Ubc4. Structure (2010) 1.58

Crystal packing analysis of murine VDAC1 crystals in a lipidic environment reveals novel insights on oligomerization and orientation. Channels (Austin) (2009) 1.57

Antibodies to Interleukin-2 Elicit Selective T Cell Subset Potentiation through Distinct Conformational Mechanisms. Immunity (2015) 1.57

Vaccinia virus proteins A52 and B14 Share a Bcl-2-like fold but have evolved to inhibit NF-kappaB rather than apoptosis. PLoS Pathog (2008) 1.57

Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design. PLoS Pathog (2016) 1.56

Structure of the HECT:ubiquitin complex and its role in ubiquitin chain elongation. EMBO Rep (2011) 1.55

Statistical analysis of interface similarity in crystals of homologous proteins. J Mol Biol (2008) 1.55

Intervening with urinary tract infections using anti-adhesives based on the crystal structure of the FimH-oligomannose-3 complex. PLoS One (2008) 1.54

Structure-based characterization of multiprotein complexes. Structure (2014) 1.54

Crystal structure of native RPE65, the retinoid isomerase of the visual cycle. Proc Natl Acad Sci U S A (2009) 1.54

Heme uptake across the outer membrane as revealed by crystal structures of the receptor-hemophore complex. Proc Natl Acad Sci U S A (2009) 1.53

Advanced ensemble modelling of flexible macromolecules using X-ray solution scattering. IUCrJ (2015) 1.53

Structure of lactococcal phage p2 baseplate and its mechanism of activation. Proc Natl Acad Sci U S A (2010) 1.53

Structural basis of potent Zika-dengue virus antibody cross-neutralization. Nature (2016) 1.52

IRAK4 dimerization and trans-autophosphorylation are induced by Myddosome assembly. Mol Cell (2014) 1.52

Announcing the worldwide Protein Data Bank. Nat Struct Biol (2003) 17.06

The worldwide Protein Data Bank (wwPDB): ensuring a single, uniform archive of PDB data. Nucleic Acids Res (2006) 13.44

CAPRI: a Critical Assessment of PRedicted Interactions. Proteins (2003) 6.36

PDBML: the representation of archival macromolecular structure data in XML. Bioinformatics (2004) 3.64

The European Bioinformatics Institute's data resources. Nucleic Acids Res (2003) 3.34

EMDataBank.org: unified data resource for CryoEM. Nucleic Acids Res (2010) 3.32

MSDmotif: exploring protein sites and motifs. BMC Bioinformatics (2008) 2.48

Outcome of a workshop on archiving structural models of biological macromolecules. Structure (2006) 2.32

Data deposition and annotation at the worldwide protein data bank. Mol Biotechnol (2008) 2.30

New electron microscopy database and deposition system. Trends Biochem Sci (2002) 2.17

MSDsite: a database search and retrieval system for the analysis and viewing of bound ligands and active sites. Proteins (2005) 2.17

Pound-wise but penny-foolish: How well do micromolecules fare in macromolecular refinement? Structure (2003) 2.14

BioMagResBank (BMRB) as a partner in the Worldwide Protein Data Bank (wwPDB): new policies affecting biomolecular NMR depositions. J Biomol NMR (2008) 1.89

Using MSDchem to search the PDB ligand dictionary. Curr Protoc Bioinformatics (2006) 1.63

The CCPN project: an interim report on a data model for the NMR community. Nat Struct Biol (2002) 1.58

The Protein Information Management System (PiMS): a generic tool for any structural biology research laboratory. Acta Crystallogr D Biol Crystallogr (2011) 1.45

EUROCarbDB: An open-access platform for glycoinformatics. Glycobiology (2010) 1.13

Representation of viruses in the remediated PDB archive. Acta Crystallogr D Biol Crystallogr (2008) 1.08

Design of a data model for developing laboratory information management and analysis systems for protein production. Proteins (2005) 1.06

Chemical substructure search in SQL. J Chem Inf Model (2009) 1.06

Data deposition and annotation at the worldwide protein data bank. Methods Mol Biol (2008) 1.00

Realism about PDB. Nat Biotechnol (2007) 0.89

Straightforward and complete deposition of NMR data to the PDBe. J Biomol NMR (2010) 0.89