Published in Protein Sci on October 01, 2010
ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL. J Mol Biol (1965) 46.35
Comparison of experimental binding data and theoretical models in proteins containing subunits. Biochemistry (1966) 16.43
Dynamic personalities of proteins. Nature (2007) 8.92
A perspective on enzyme catalysis. Science (2003) 5.15
The role of dynamics in allosteric regulation. Curr Opin Struct Biol (2003) 4.82
Molecular dynamics and protein function. Proc Natl Acad Sci U S A (2005) 4.70
Relating protein motion to catalysis. Annu Rev Biochem (2006) 4.50
Enzyme dynamics and hydrogen tunnelling in a thermophilic alcohol dehydrogenase. Nature (1999) 3.63
Ligand binding and internal equilibria in proteins. Biochemistry (1972) 2.97
The changing landscape of protein allostery. Curr Opin Struct Biol (2006) 2.90
Quenching of fluorescence by oxygen. A probe for structural fluctuations in macromolecules. Biochemistry (1973) 2.48
Environmentally coupled hydrogen tunneling. Linking catalysis to dynamics. Eur J Biochem (2002) 2.14
Kinetic studies of glutamate dehydrogenase with glutamate and norvaline as substrates. Coenzyme activation and negative homotropic interactions in allosteric enzymes. Biochem J (1969) 2.10
Challenges in enzyme mechanism and energetics. Annu Rev Biochem (2003) 2.00
A dynamic analysis of the rotation mechanism for conformational change in F(1)-ATPase. Structure (2002) 1.84
Reaction of pyridine nucleotide analogues with dehydrogenases. J Biol Chem (1956) 1.75
Thermal-activated protein mobility and its correlation with catalysis in thermophilic alcohol dehydrogenase. Proc Natl Acad Sci U S A (2004) 1.73
Antagonistic homotropic interactions as a possible explanation of coenzyme activation of glutamate dehydrogenase. FEBS Lett (1968) 1.71
A perspective of the binding change mechanism for ATP synthesis. FASEB J (1989) 1.43
Hyperinsulinism/hyperammonemia syndrome in children with regulatory mutations in the inhibitory guanosine triphosphate-binding domain of glutamate dehydrogenase. J Clin Endocrinol Metab (2001) 1.42
The binding of oxidized coenzymes by glutamate dehydrogenase and the effects of glutarate and purine nucleotides. Biochem J (1972) 1.39
Structural biology. Dynamic visions of enzymatic reactions. Science (2006) 1.30
Structures of bovine glutamate dehydrogenase complexes elucidate the mechanism of purine regulation. J Mol Biol (2001) 1.29
GLUTAMATE DEHYDROGENASE. VI. SURVEY OF PURINE NUCLEOTIDE AND OTHER EFFECTS ON THE ENZYME FROM VARIOUS SOURCES. J Biol Chem (1965) 1.28
The structure of apo human glutamate dehydrogenase details subunit communication and allostery. J Mol Biol (2002) 1.27
Regulation of bovine glutamate dehydrogenase. The effects of pH and ADP. J Biol Chem (1982) 1.19
A conformational transition of the oligomer of glutamate dehydrogenase induced by half-saturation with NAD + or NADP + . Biochim Biophys Acta (1973) 1.16
Crystal structure and amide H/D exchange of binary complexes of alcohol dehydrogenase from Bacillus stearothermophilus: insight into thermostability and cofactor binding. Biochemistry (2004) 1.13
The structure of bovine glutamate dehydrogenase provides insights into the mechanism of allostery. Structure (1999) 1.11
Vmax regulation through domain and subunit changes. The active form of phosphoglycerate dehydrogenase. Biochemistry (2005) 1.11
Equilibrium perturbation by isotope substitution. Biochemistry (1975) 1.09
Expression, purification and characterization of human glutamate dehydrogenase (GDH) allosteric regulatory mutations. Biochem J (2002) 1.08
Assessment of the allosteric mechanism of aspartate transcarbamoylase based on the crystalline structure of the unregulated catalytic subunit. Proc Natl Acad Sci U S A (1999) 1.08
Binding of bisubstrate analog promotes large structural changes in the unregulated catalytic trimer of aspartate transcarbamoylase: implications for allosteric regulation. Proc Natl Acad Sci U S A (2000) 1.05
Kinetic mechanism of glutamate dehydrogenase. Biochemistry (1980) 1.04
Subunit dissociation and unfolding of bovine liver glutamate dehydrogenase induced by guanidine hydrochloride. Biochim Biophys Acta (1982) 0.97
Dual nucleotide specificity of bovine glutamate dehydrogenase. The role of negative co-operativity. Biochem J (1980) 0.94
Catalytic activity of bovine glutamate dehydrogenase requires a hexamer structure. Biochem J (1984) 0.94
The subunits of bovine liver glutamate dehydrogenase: demonstration of a single peptide chain. J Mol Biol (1966) 0.91
Negative co-operativity in glutamate dehydrogenase. Involvement of the 2-position in glutamate in the induction of conformational changes. Biochem J (1985) 0.87
Transient-state intermediates involved in the hydride transfer step of the glutamate dehydrogenase reaction. Biochem Biophys Res Commun (1970) 0.85
A steady-state random-order mechanism for the oxidative deamination of norvaline by glutamate dehydrogenase. Biochem J (1983) 0.83
Nickel-specific response in the transcriptional regulator, Escherichia coli NikR. J Am Chem Soc (2007) 1.21
Mechanism of Mss116 ATPase reveals functional diversity of DEAD-Box proteins. J Mol Biol (2011) 1.17
Insights regarding guanine nucleotide exchange from the structure of a DENN-domain protein complexed with its Rab GTPase substrate. Proc Natl Acad Sci U S A (2011) 1.15
Foundational concepts and underlying theories for majors in "biochemistry and molecular biology". Biochem Mol Biol Educ (2013) 1.09
Met-Independent Hepatocyte Growth Factor-mediated regulation of cell adhesion in human prostate cancer cells. BMC Cancer (2006) 1.07
ATP utilization and RNA conformational rearrangement by DEAD-box proteins. Annu Rev Biophys (2012) 1.05
Identification of cation-binding sites on actin that drive polymerization and modulate bending stiffness. Proc Natl Acad Sci U S A (2012) 1.01
Cellular interactions in the tropism of prostate cancer to bone. Int J Cancer (2004) 1.00
What skills should students of undergraduate biochemistry and molecular biology programs have upon graduation? Biochem Mol Biol Educ (2013) 0.98
Essential concepts and underlying theories from physics, chemistry, and mathematics for "biochemistry and molecular biology" majors. Biochem Mol Biol Educ (2013) 0.93
Sonographic findings of necrotizing fasciitis in the breast. J Clin Ultrasound (2008) 0.89
Organelle and translocatable forms of glyoxysomal malate dehydrogenase. The effect of the N-terminal presequence. FEBS J (2005) 0.88
The Trauma Recovery Group: a cognitive-behavioral program for post-traumatic stress disorder in persons with severe mental illness. Community Ment Health J (2007) 0.85
Introduction: promoting concept driven teaching strategies in biochemistry and molecular biology. Biochem Mol Biol Educ (2013) 0.81
Alteration in the cavity size adjacent to the active site of RB69 DNA polymerase changes its conformational dynamics. Nucleic Acids Res (2013) 0.76
A novel mechanism of V-type zinc inhibition of glutamate dehydrogenase results from disruption of subunit interactions necessary for efficient catalysis. FEBS J (2011) 0.75
Climate related events and community preparedness. Int J Circumpolar Health (2005) 0.75
Commentary: Biochemistry and molecular biology educators launch national network. Biochem Mol Biol Educ (2010) 0.75