1
|
Total synthesis of (+)-dactylolide through an efficient sequential Peterson olefination and Prins cyclization reaction.
|
Angew Chem Int Ed Engl
|
2005
|
2.00
|
2
|
An experimental and computational approach to defining structure/reactivity relationships for intramolecular addition reactions to bicyclic epoxonium ions.
|
J Am Chem Soc
|
2007
|
1.70
|
3
|
Diastereoselective tetrahydropyrone synthesis through transition-metal-free oxidative carbon-hydrogen bond activation.
|
Angew Chem Int Ed Engl
|
2008
|
1.43
|
4
|
Tuning reactivity and chemoselectivity in electron transfer initiated cyclization reactions: applications to carbon-carbon bond formation.
|
J Am Chem Soc
|
2003
|
1.27
|
5
|
Oxidative carbocation formation in macrocycles: synthesis of the neopeltolide macrocycle.
|
Angew Chem Int Ed Engl
|
2009
|
1.26
|
6
|
Synthesis of the C16-C35 fragment of integramycin using olefin hydroesterification as a linchpin reaction.
|
Org Lett
|
2004
|
1.10
|
7
|
Structurally and stereochemically diverse tetrahydropyran synthesis through oxidative C-H bond activation.
|
Angew Chem Int Ed Engl
|
2010
|
1.07
|
8
|
Concise and stereoselective synthesis of the N7-C25 fragment of psymberin.
|
Org Lett
|
2005
|
1.06
|
9
|
Mechanistic Analysis of Oxidative C-H Cleavages Using Inter- and Intramolecular Kinetic Isotope Effects.
|
Tetrahedron
|
2009
|
1.04
|
10
|
Total synthesis of theopederin D.
|
Angew Chem Int Ed Engl
|
2008
|
1.04
|
11
|
Structure-reactivity relationships in oxidative carbon-carbon bond forming reactions: a mild and efficient approach to stereoselective syntheses of 2,6-disubstituted tetrahydropyrones.
|
J Am Chem Soc
|
2004
|
1.04
|
12
|
Cyclization reactions through DDQ-mediated vinyl oxazolidinone oxidation.
|
Org Lett
|
2009
|
1.04
|
13
|
Total synthesis and biological evaluation of pederin, psymberin, and highly potent analogs.
|
J Am Chem Soc
|
2011
|
1.04
|
14
|
Oxidative cleavage in the construction of complex molecules: synthesis of the leucascandrolide A macrolactone.
|
Angew Chem Int Ed Engl
|
2007
|
1.03
|
15
|
Multicomponent approach to the synthesis of oxidized amides through nitrile hydrozirconation.
|
Org Lett
|
2007
|
1.03
|
16
|
Stereochemical assignment of the C1-C6 fragment of psymberin by synthesis and natural product degradation.
|
Org Lett
|
2005
|
1.01
|
17
|
Stereoselective synthesis of tertiary ethers through geometric control of highly substituted oxocarbenium ions.
|
Angew Chem Int Ed Engl
|
2010
|
1.00
|
18
|
One-pot synthesis of bicyclic beta-alkoxy amides from cyanohydrin ethers.
|
Org Lett
|
2008
|
0.98
|
19
|
Electron transfer initiated heterogenerative cascade cyclizations: polyether synthesis under nonacidic conditions.
|
Org Lett
|
2002
|
0.98
|
20
|
Stereoselective synthesis of spirooxindole amides through nitrile hydrozirconation.
|
Org Lett
|
2010
|
0.97
|
21
|
Multicomponent synthesis of alpha-branched amides.
|
Org Lett
|
2009
|
0.94
|
22
|
Construction of a bicyclic beta-benzyloxy and beta-hydroxy amide library through a multicomponent cyclization reaction.
|
J Comb Chem
|
2010
|
0.93
|
23
|
Oxidation-resistant fluorogenic probe for mercury based on alkyne oxymercuration.
|
J Am Chem Soc
|
2008
|
0.92
|
24
|
Isolation, biological activity, synthesis, and medicinal chemistry of the pederin/mycalamide family of natural products.
|
Nat Prod Rep
|
2012
|
0.90
|
25
|
An oxidative entry into the amido trioxadecalin ring system.
|
Org Lett
|
2003
|
0.90
|
26
|
Cyclopropane compatibility with oxidative carbocation formation: total synthesis of clavosolide A.
|
Org Lett
|
2012
|
0.88
|
27
|
Studies toward the unique pederin family member psymberin: structure-activity relationships, biochemical studies, and genetics identify the mode-of-action of psymberin.
|
J Am Chem Soc
|
2012
|
0.86
|
28
|
Total synthesis of the protein phosphatase 2A inhibitor lactodehydrothyrsiferol.
|
Angew Chem Int Ed Engl
|
2011
|
0.86
|
29
|
Total synthesis of neopeltolide and analogs.
|
Tetrahedron
|
2010
|
0.85
|
30
|
Synthesis of sulfur-containing heterocycles through oxidative carbon-hydrogen bond functionalization.
|
Org Lett
|
2012
|
0.85
|
31
|
Bimolecular Coupling Reactions through Oxidatively Generated Aromatic Cations: Scope and Stereocontrol.
|
Tetrahedron
|
2013
|
0.84
|
32
|
Total synthesis of pederin and analogues.
|
Angew Chem Int Ed Engl
|
2010
|
0.83
|
33
|
Aromatic cations from oxidative carbon-hydrogen bond cleavage in bimolecular carbon-carbon bond forming reactions.
|
J Org Chem
|
2012
|
0.83
|
34
|
Rapid catalyst screening by a continuous-flow microreactor interfaced with ultra-high-pressure liquid chromatography.
|
J Org Chem
|
2010
|
0.82
|
35
|
Synthesis of bridged inside-outside bicyclic ethers through oxidative transannular cyclization reactions.
|
Org Lett
|
2012
|
0.82
|
36
|
2,3-Dichloro-5,6-dicyano-1,4-benzoquinone-catalyzed reactions employing MnO2 as a stoichiometric oxidant.
|
Org Lett
|
2010
|
0.82
|
37
|
Synthesis and biological evaluation of neopeltolide and analogs.
|
J Org Chem
|
2012
|
0.82
|
38
|
Cascade approach to stereoselective polycyclic ether formation: epoxides as trapping agents in the transposition of allylic alcohols.
|
Angew Chem Int Ed Engl
|
2012
|
0.81
|
39
|
Versatile approach to α-alkoxy carbamate synthesis and stimulus-responsive alcohol release.
|
Org Biomol Chem
|
2012
|
0.80
|
40
|
Oxidative synthesis of cyclic acyl aminals through carbon-carbon sigma-bond activation.
|
Org Lett
|
2002
|
0.79
|
41
|
The "aqueous" Prins reaction.
|
Org Lett
|
2003
|
0.79
|
42
|
Gold-catalyzed synthesis of oxygen- and nitrogen-containing heterocycles from alkynyl ethers: application to the total synthesis of andrachcinidine.
|
J Org Chem
|
2007
|
0.79
|
43
|
Stereoselective heterocycle synthesis through oxidative carbon-hydrogen bond activation.
|
Curr Opin Drug Discov Devel
|
2010
|
0.77
|
44
|
Diversity-oriented synthesis of a library of substituted tetrahydropyrones using oxidative carbon-hydrogen bond activation and click chemistry.
|
Molecules
|
2011
|
0.77
|
45
|
Spiroacetal formation through telescoped cycloaddition and carbon-hydrogen bond functionalization: total synthesis of bistramide A.
|
Angew Chem Int Ed Engl
|
2014
|
0.75
|
46
|
Construction of a spirooxindole amide library through nitrile hydrozirconation-acylation-cyclization cascade.
|
ACS Comb Sci
|
2013
|
0.75
|
47
|
Stereocontrolled cyanohydrin ether synthesis through chiral Brønsted acid-mediated vinyl ether hydrocyanation.
|
J Org Chem
|
2013
|
0.75
|
48
|
Intramolecular electron transfer initiated cation and radical formation through carbon-carbon bond activation.
|
Org Lett
|
2007
|
0.75
|
49
|
Gold-catalyzed heterocycle synthesis using homopropargylic ethers as latent electrophiles.
|
Org Lett
|
2006
|
0.75
|
50
|
Heterocycle synthesis based on allylic alcohol transposition using traceless trapping groups.
|
Angew Chem Int Ed Engl
|
2014
|
0.75
|
51
|
Investigations of the scope and mechanism of the tandem hydroesterification/lactonization reaction.
|
Org Lett
|
2004
|
0.75
|
52
|
Oxidative cyclorelease from soluble polymeric supports.
|
J Org Chem
|
2005
|
0.75
|