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Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery.
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Science
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2011
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2
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A role for apical membrane antigen 1 during invasion of hepatocytes by Plasmodium falciparum sporozoites.
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J Biol Chem
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2003
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2.84
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3
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Hepatocyte CD81 is required for Plasmodium falciparum and Plasmodium yoelii sporozoite infectivity.
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Nat Med
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2002
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2.46
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4
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Perforin-dependent brain-infiltrating cytotoxic CD8+ T lymphocytes mediate experimental cerebral malaria pathogenesis.
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J Immunol
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2003
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2.22
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5
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Towards an in vitro model of Plasmodium hypnozoites suitable for drug discovery.
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PLoS One
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2011
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1.60
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6
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Vaccination with live Plasmodium yoelii blood stage parasites under chloroquine cover induces cross-stage immunity against malaria liver stage.
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J Immunol
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2008
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1.53
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7
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The sensing of poorly deformable red blood cells by the human spleen can be mimicked in vitro.
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Blood
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2010
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1.52
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8
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Host scavenger receptor SR-BI plays a dual role in the establishment of malaria parasite liver infection.
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Cell Host Microbe
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2008
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1.50
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9
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A plant-derived morphinan as a novel lead compound active against malaria liver stages.
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PLoS Med
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2006
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1.49
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10
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Plasmodium falciparum--infected erythrocyte adhesion induces caspase activation and apoptosis in human endothelial cells.
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J Infect Dis
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2003
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1.44
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11
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Rapid species diagnosis for invasive candidiasis using mass spectrometry.
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PLoS One
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2010
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12
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Sterile protection against malaria is independent of immune responses to the circumsporozoite protein.
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PLoS One
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2007
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13
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Helminth infections are associated with protection from cerebral malaria and increased nitrogen derivatives concentrations in Thailand.
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Am J Trop Med Hyg
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2002
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1.31
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14
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MALDI-TOF MS-based drug susceptibility testing of pathogens: the example of Candida albicans and fluconazole.
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Proteomics
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2009
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1.26
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15
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Gene disruption of Plasmodium falciparum p52 results in attenuation of malaria liver stage development in cultured primary human hepatocytes.
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PLoS One
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2008
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16
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Expression of human CD81 differently affects host cell susceptibility to malaria sporozoites depending on the Plasmodium species.
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Cell Microbiol
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2006
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1.25
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17
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Genetically attenuated P36p-deficient Plasmodium berghei sporozoites confer long-lasting and partial cross-species protection.
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Int J Parasitol
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2007
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1.24
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18
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Cholesterol contributes to the organization of tetraspanin-enriched microdomains and to CD81-dependent infection by malaria sporozoites.
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J Cell Sci
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2006
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1.23
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19
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Scavenger receptor BI boosts hepatocyte permissiveness to Plasmodium infection.
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Cell Host Microbe
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2008
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1.20
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20
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Temperature shift and host cell contact up-regulate sporozoite expression of Plasmodium falciparum genes involved in hepatocyte infection.
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PLoS Pathog
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2008
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1.19
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21
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Identification of new antimalarial drugs by linear discriminant analysis and topological virtual screening.
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J Antimicrob Chemother
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2006
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1.18
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22
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Selection of a trioxaquine as an antimalarial drug candidate.
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Proc Natl Acad Sci U S A
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2008
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1.18
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23
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In vitro activities of 25 quinolones and fluoroquinolones against liver and blood stage Plasmodium spp.
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Antimicrob Agents Chemother
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2003
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1.16
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24
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Recombinant human IFN-alpha inhibits cerebral malaria and reduces parasite burden in mice.
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J Immunol
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2007
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1.14
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25
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Inhibitory effect of TNF-α on malaria pre-erythrocytic stage development: influence of host hepatocyte/parasite combinations.
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PLoS One
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2011
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1.12
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26
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Assessing the adequacy of attenuation of genetically modified malaria parasite vaccine candidates.
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Vaccine
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2012
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27
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Decreased hemoglobin concentrations, hyperparasitemia, and severe malaria are associated with increased Plasmodium falciparum gametocyte carriage.
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J Parasitol
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2002
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1.10
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28
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Blood-brain barrier breakdown during cerebral malaria: suicide or murder?
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Thromb Haemost
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2005
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1.09
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29
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New approach for high-throughput screening of drug activity on Plasmodium liver stages.
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Antimicrob Agents Chemother
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2006
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1.08
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30
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Rho kinase inhibition in severe malaria: thwarting parasite-induced collateral damage to endothelia.
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J Infect Dis
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2008
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1.06
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31
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Alternative invasion pathways for Plasmodium berghei sporozoites.
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Int J Parasitol
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2006
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1.06
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32
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The N'-terminal domain of glyceraldehyde-3-phosphate dehydrogenase of the apicomplexan Plasmodium falciparum mediates GTPase Rab2-dependent recruitment to membranes.
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Biol Chem
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2003
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1.05
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33
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Hepatocyte permissiveness to Plasmodium infection is conveyed by a short and structurally conserved region of the CD81 large extracellular domain.
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PLoS Pathog
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2008
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1.05
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34
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Transfusion-transmitted malaria.
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Intensive Care Med
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2004
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1.04
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35
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Two Plasmodium 6-Cys family-related proteins have distinct and critical roles in liver-stage development.
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FASEB J
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2014
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1.04
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36
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Pseudallescheria/Scedosporium complex species identification by Matrix-Assisted Laser Desorption Ionization Time-Of-Flight Mass Spectrometry.
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Med Mycol
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2011
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1.02
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37
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Whole-transcriptome analysis of Plasmodium falciparum field isolates: identification of new pathogenicity factors.
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J Infect Dis
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2007
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1.01
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38
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New active drugs against liver stages of Plasmodium predicted by molecular topology.
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Antimicrob Agents Chemother
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2008
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1.01
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39
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A role for immune responses against non-CS components in the cross-species protection induced by immunization with irradiated malaria sporozoites.
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PLoS One
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2009
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1.01
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40
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The Plasmodium sporozoite survives RTS,S vaccination.
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Trends Parasitol
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2005
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41
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Transient supplementation of superoxide dismutase protects endothelial cells against Plasmodium falciparum-induced oxidative stress.
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Mol Biochem Parasitol
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2006
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0.97
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42
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Transcription status of vaccine candidate genes of Plasmodium falciparum during the hepatic phase of its life cycle.
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Parasitol Res
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2004
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43
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Atorvastatin prevents Plasmodium falciparum cytoadherence and endothelial damage.
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Malar J
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2011
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44
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Induction of the CD23/nitric oxide pathway in endothelial cells downregulates ICAM-1 expression and decreases cytoadherence of Plasmodium falciparum-infected erythrocytes.
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Cell Microbiol
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2004
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45
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Structure-activity-based design of a synthetic malaria peptide eliciting sporozoite inhibitory antibodies in a virosomal formulation.
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Chem Biol
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2007
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46
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Hepatitis C virus infection may lead to slower emergence of P. falciparum in blood.
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PLoS One
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2011
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Intermittent preventive antimalarial treatment to children (IPTc): firebreak or fire trap?
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Trends Parasitol
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2008
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Antioxidant and anti-inflammatory properties of a Cucumis melo LC. extract rich in superoxide dismutase activity.
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J Ethnopharmacol
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2004
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Differential aiolos expression in human hematopoietic subpopulations.
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Leuk Res
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Metabolic acidosis induced by Plasmodium falciparum intraerythrocytic stages alters blood-brain barrier integrity.
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J Cereb Blood Flow Metab
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2010
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Plasmodium falciparum-infected mice: more than a tour de force.
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Trends Parasitol
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2007
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Potential value of Plasmodium falciparum-associated antigen and antibody detection for screening of blood donors to prevent transfusion-transmitted malaria.
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2002
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Malaria sporozoite: migrating for a living.
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Trends Mol Med
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2004
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IgE mediates killing of intracellular Toxoplasma gondii by human macrophages through CD23-dependent, interleukin-10 sensitive pathway.
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PLoS One
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2011
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55
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Aspergillus flavus brain abscesses associated with hepatic amebiasis in a non-neutropenic man in Senegal.
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Am J Trop Med Hyg
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2009
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A virosomal malaria peptide vaccine elicits a long-lasting sporozoite-inhibitory antibody response in a phase 1a clinical trial.
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PLoS One
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2007
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Testing blood donors for Chagas disease in the Paris area, France: first results after 18 months of screening.
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Transfusion
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2009
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Multilocus phylogeny and MALDI-TOF analysis of the plant pathogenic species Alternaria dauci and relatives.
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Fungal Biol
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2012
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Type I interferons contribute to experimental cerebral malaria development in response to sporozoite or blood-stage Plasmodium berghei ANKA.
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Eur J Immunol
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Inhibition of Plasmodium falciparum field isolates-mediated endothelial cell apoptosis by Fasudil: therapeutic implications for severe malaria.
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PLoS One
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Delayed-onset hemolytic anemia in patients with travel-associated severe malaria treated with artesunate, France, 2011-2013.
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Emerg Infect Dis
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2015
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Skin-draining lymph node priming is sufficient to induce sterile immunity against pre-erythrocytic malaria.
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EMBO Mol Med
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2012
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Redox-dependent apoptosis in human endothelial cells after adhesion of Plasmodium falciparum-infected erythrocytes.
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Ann N Y Acad Sci
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2003
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Isolation and antimalarial activity of new morphinan alkaloids on Plasmodium yoelii liver stage.
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Bioorg Med Chem
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2008
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Deregulation of Aiolos expression in chronic lymphocytic leukemia is associated with epigenetic modifications.
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Blood
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2010
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Transcriptome of 3D7 and its gametocyte-less derivative F12 Plasmodium falciparum clones during erythrocytic development using a gene-specific microarray assigned to gene regulation, cell cycle and transcription factors.
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Gene
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2004
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67
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The Ig domain protein CD9P-1 down-regulates CD81 ability to support Plasmodium yoelii infection.
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J Biol Chem
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2009
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Submicroscopic Plasmodium falciparum infections before and after sulfadoxine-pyrimethamine and artesunate association treatment in Dienga, Southeastern Gabon.
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Clin Med Res
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2006
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69
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Laser capture microdissection of Plasmodium falciparum liver stages for mRNA analysis.
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Mol Biochem Parasitol
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2002
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70
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Deletion of T cells bearing the V beta8.1 T-cell receptor following mouse mammary tumor virus 7 integration confers resistance to murine cerebral malaria.
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Infect Immun
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2002
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Specific targeting of caspase-9/PP2A interaction as potential new anti-cancer therapy.
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PLoS One
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2013
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CD23 mediates antimycobacterial activity of human macrophages.
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Infect Immun
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2009
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Canine visceral leishmaniasis: comparison of in vitro leishmanicidal activity of marbofloxacin, meglumine antimoniate and sodium stibogluconate.
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Vet Parasitol
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Antimalarial activity of crambescidin 800 and synthetic analogues against liver and blood stage of Plasmodium sp.
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J Antibiot (Tokyo)
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2006
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An enhancer-like region regulates hrp3 promoter stage-specific gene expression in the human malaria parasite Plasmodium falciparum.
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Biochim Biophys Acta
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2007
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Pooling aqueous humor samples: bias in 2D-LC-MS/MS strategy?
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J Proteome Res
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2010
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Cytoadherence and genotype of Plasmodium falciparum strains from symptomatic children in Franceville, southeastern Gabon.
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Clin Med Res
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2007
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Supplementation with gliadin-combined plant superoxide dismutase extract promotes antioxidant defences and protects against oxidative stress.
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Phytother Res
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2004
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Plasmodium falciparum: hrp3 promoter region is associated with stage-specificity and episomal recombination.
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Exp Parasitol
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2007
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Laser capture microdissection of hepatic stages of the human parasite Plasmodium falciparum for molecular analysis.
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Methods Mol Biol
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2005
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81
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High levels of immunoglobulin E autoantibody to 14-3-3 epsilon protein correlate with protection against severe Plasmodium falciparum malaria.
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J Infect Dis
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2012
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82
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A mouse model for Candida glabrata hematogenous disseminated infection starting from the gut: evaluation of strains with different adhesion properties.
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PLoS One
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2013
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Erratum: SC83288 is a clinical development candidate for the treatment of severe malaria.
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Nat Commun
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1,3,5-Triazepane-2,6-diones as structurally diverse and conformationally constrained dipeptide mimetics: identification of malaria liver stage inhibitors from a small pilot library.
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Chemistry
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2006
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[CD81: a tetraspanin implicated in Plasmodium infection].
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Med Sci (Paris)
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Drug hypersensitivity syndrome induced by meglumine antimoniate.
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Am J Trop Med Hyg
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Wheat gliadin promotes the interleukin-4-induced IgE production by normal human peripheral mononuclear cells through a redox-dependent mechanism.
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Cytokine
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2003
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