| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Cancer-associated adipocytes exhibit an activated phenotype and contribute to breast cancer invasion.
|
Cancer Res
|
2011
|
2.85
|
|
2
|
Metabolic adaptation to a high-fat diet is associated with a change in the gut microbiota.
|
Gut
|
2011
|
2.50
|
|
3
|
Apelin, a newly identified adipokine up-regulated by insulin and obesity.
|
Endocrinology
|
2005
|
1.88
|
|
4
|
LPA1 receptor activation promotes renal interstitial fibrosis.
|
J Am Soc Nephrol
|
2007
|
1.51
|
|
5
|
Apelin stimulates glucose utilization in normal and obese insulin-resistant mice.
|
Cell Metab
|
2008
|
1.48
|
|
6
|
Altered gut microbiota and endocannabinoid system tone in obese and diabetic leptin-resistant mice: impact on apelin regulation in adipose tissue.
|
Front Microbiol
|
2011
|
1.46
|
|
7
|
Autotaxin is released from adipocytes, catalyzes lysophosphatidic acid synthesis, and activates preadipocyte proliferation. Up-regulated expression with adipocyte differentiation and obesity.
|
J Biol Chem
|
2003
|
1.39
|
|
8
|
TNFalpha up-regulates apelin expression in human and mouse adipose tissue.
|
FASEB J
|
2006
|
1.34
|
|
9
|
Brain glucagon-like peptide 1 signaling controls the onset of high-fat diet-induced insulin resistance and reduces energy expenditure.
|
Endocrinology
|
2008
|
1.25
|
|
10
|
Adipocyte-derived fibroblasts promote tumor progression and contribute to the desmoplastic reaction in breast cancer.
|
Cancer Res
|
2013
|
1.24
|
|
11
|
Lipolysis is altered in MHC class I zinc-alpha(2)-glycoprotein deficient mice.
|
FEBS Lett
|
2007
|
1.19
|
|
12
|
Unraveling the obesity and breast cancer links: a role for cancer-associated adipocytes?
|
Endocr Dev
|
2010
|
1.18
|
|
13
|
Adipose tissue and breast epithelial cells: a dangerous dynamic duo in breast cancer.
|
Cancer Lett
|
2012
|
1.16
|
|
14
|
Obesity-induced lymphocyte hyperresponsiveness to chemokines: a new mechanism of Fatty liver inflammation in obese mice.
|
Gastroenterology
|
2008
|
1.15
|
|
15
|
Apelin, diabetes, and obesity.
|
Endocrine
|
2011
|
1.14
|
|
16
|
Apelin, a promising target for type 2 diabetes treatment?
|
Trends Endocrinol Metab
|
2012
|
1.14
|
|
17
|
Lysophosphatidic acid inhibits adipocyte differentiation via lysophosphatidic acid 1 receptor-dependent down-regulation of peroxisome proliferator-activated receptor gamma2.
|
J Biol Chem
|
2005
|
1.13
|
|
18
|
Adipose-specific disruption of autotaxin enhances nutritional fattening and reduces plasma lysophosphatidic acid.
|
J Lipid Res
|
2011
|
1.11
|
|
19
|
LRP1 receptor controls adipogenesis and is up-regulated in human and mouse obese adipose tissue.
|
PLoS One
|
2009
|
1.08
|
|
20
|
Apelin prevents cardiac fibroblast activation and collagen production through inhibition of sphingosine kinase 1.
|
Eur Heart J
|
2011
|
1.06
|
|
21
|
Apelin treatment increases complete Fatty Acid oxidation, mitochondrial oxidative capacity, and biogenesis in muscle of insulin-resistant mice.
|
Diabetes
|
2011
|
1.05
|
|
22
|
Lysophosphatidic acid and renal fibrosis.
|
Biochim Biophys Acta
|
2008
|
1.04
|
|
23
|
Activation of catalase by apelin prevents oxidative stress-linked cardiac hypertrophy.
|
FEBS Lett
|
2010
|
1.03
|
|
24
|
p53-PGC-1α pathway mediates oxidative mitochondrial damage and cardiomyocyte necrosis induced by monoamine oxidase-A upregulation: role in chronic left ventricular dysfunction in mice.
|
Antioxid Redox Signal
|
2012
|
1.02
|
|
25
|
Deletion of Lkb1 in pro-opiomelanocortin neurons impairs peripheral glucose homeostasis in mice.
|
Diabetes
|
2011
|
1.02
|
|
26
|
Murine and human autotaxin alpha, beta, and gamma isoforms: gene organization, tissue distribution, and biochemical characterization.
|
J Biol Chem
|
2008
|
1.02
|
|
27
|
Ventromedial hypothalamic nitric oxide production is necessary for hypoglycemia detection and counterregulation.
|
Diabetes
|
2009
|
1.00
|
|
28
|
Food intake adaptation to dietary fat involves PSA-dependent rewiring of the arcuate melanocortin system in mice.
|
J Neurosci
|
2012
|
0.99
|
|
29
|
Cancer-associated adipocytes promotes breast tumor radioresistance.
|
Biochem Biophys Res Commun
|
2011
|
0.99
|
|
30
|
Noonan syndrome-causing SHP2 mutants inhibit insulin-like growth factor 1 release via growth hormone-induced ERK hyperactivation, which contributes to short stature.
|
Proc Natl Acad Sci U S A
|
2012
|
0.98
|
|
31
|
Apelin and APJ regulation in adipose tissue and skeletal muscle of type 2 diabetic mice and humans.
|
Am J Physiol Endocrinol Metab
|
2010
|
0.98
|
|
32
|
Secretion of a lysophospholipase D activity by adipocytes: involvement in lysophosphatidic acid synthesis.
|
J Lipid Res
|
2002
|
0.97
|
|
33
|
Is Crohn's creeping fat an adipose tissue?
|
Inflamm Bowel Dis
|
2011
|
0.96
|
|
34
|
Cathepsin-D, a key protease in breast cancer, is up-regulated in obese mouse and human adipose tissue, and controls adipogenesis.
|
PLoS One
|
2011
|
0.96
|
|
35
|
Central apelin controls glucose homeostasis via a nitric oxide-dependent pathway in mice.
|
Antioxid Redox Signal
|
2011
|
0.96
|
|
36
|
Effect of hypocaloric diet-induced weight loss in obese women on plasma apelin and adipose tissue expression of apelin and APJ.
|
Eur J Endocrinol
|
2008
|
0.94
|
|
37
|
Lysophosphatidic acid-1-receptor targeting agents for fibrosis.
|
Expert Opin Investig Drugs
|
2011
|
0.94
|
|
38
|
Jejunum inflammation in obese and diabetic mice impairs enteric glucose detection and modifies nitric oxide release in the hypothalamus.
|
Antioxid Redox Signal
|
2010
|
0.93
|
|
39
|
Positive regulation of DNA double strand break repair activity during differentiation of long life span cells: the example of adipogenesis.
|
PLoS One
|
2008
|
0.93
|
|
40
|
Expression of ectolipid phosphate phosphohydrolases in 3T3F442A preadipocytes and adipocytes. Involvement in the control of lysophosphatidic acid production.
|
J Biol Chem
|
2002
|
0.92
|
|
41
|
Involvement of cholecystokinin 2 receptor in food intake regulation: hyperphagia and increased fat deposition in cholecystokinin 2 receptor-deficient mice.
|
Endocrinology
|
2006
|
0.92
|
|
42
|
Lipopolysaccharides-mediated increase in glucose-stimulated insulin secretion: involvement of the GLP-1 pathway.
|
Diabetes
|
2013
|
0.91
|
|
43
|
Secretion and lysophospholipase D activity of autotaxin by adipocytes are controlled by N-glycosylation and signal peptidase.
|
Biochim Biophys Acta
|
2006
|
0.91
|
|
44
|
Depot-specific regulation of autotaxin with obesity in human adipose tissue.
|
J Physiol Biochem
|
2012
|
0.90
|
|
45
|
Alteration of amine oxidase activity in the adipose tissue of obese subjects.
|
Obes Res
|
2004
|
0.88
|
|
46
|
Loss of ATM positively regulates the expression of hypoxia inducible factor 1 (HIF-1) through oxidative stress: Role in the physiopathology of the disease.
|
Cell Cycle
|
2010
|
0.88
|
|
47
|
Adipogenesis-related increase of semicarbazide-sensitive amine oxidase and monoamine oxidase in human adipocytes.
|
Biochimie
|
2007
|
0.88
|
|
48
|
Metabolic endotoxemia directly increases the proliferation of adipocyte precursors at the onset of metabolic diseases through a CD14-dependent mechanism.
|
Mol Metab
|
2013
|
0.88
|
|
49
|
Circadian feeding drive of metabolic activity in adipose tissue and not hyperphagia triggers overweight in mice: is there a role of the pentose-phosphate pathway?
|
Endocrinology
|
2011
|
0.87
|
|
50
|
Regulation of secreted protein acidic and rich in cysteine during adipose conversion and adipose tissue hyperplasia.
|
Obesity (Silver Spring)
|
2006
|
0.86
|
|
51
|
Hypothalamic apelin/reactive oxygen species signaling controls hepatic glucose metabolism in the onset of diabetes.
|
Antioxid Redox Signal
|
2013
|
0.86
|
|
52
|
The intestinal glucose-apelin cycle controls carbohydrate absorption in mice.
|
Gastroenterology
|
2013
|
0.86
|
|
53
|
Apelin and the proopiomelanocortin system: a new regulatory pathway of hypothalamic α-MSH release.
|
Am J Physiol Endocrinol Metab
|
2011
|
0.85
|
|
54
|
Apelin, a novel adipokine over-produced in obesity: friend or foe?
|
Mol Cell Endocrinol
|
2005
|
0.84
|
|
55
|
Tyramine stimulates glucose uptake in insulin-sensitive tissues in vitro and in vivo via its oxidation by amine oxidases.
|
J Pharmacol Exp Ther
|
2002
|
0.83
|
|
56
|
Chronic benzylamine administration in the drinking water improves glucose tolerance, reduces body weight gain and circulating cholesterol in high-fat diet-fed mice.
|
Pharmacol Res
|
2010
|
0.83
|
|
57
|
The transcriptional co-activator PGC-1alpha up regulates apelin in human and mouse adipocytes.
|
Regul Pept
|
2008
|
0.82
|
|
58
|
Apelin is a novel islet peptide.
|
Regul Pept
|
2010
|
0.82
|
|
59
|
Semicarbazide-sensitive amine oxidase/vascular adhesion protein-1 deficiency reduces leukocyte infiltration into adipose tissue and favors fat deposition.
|
Am J Pathol
|
2009
|
0.82
|
|
60
|
Methylamine but not mafenide mimics insulin-like activity of the semicarbazide-sensitive amine oxidase-substrate benzylamine on glucose tolerance and on human adipocyte metabolism.
|
Pharmacol Res
|
2005
|
0.82
|
|
61
|
Hypoxia inhibits Cavin-1 and Cavin-2 expression and down-regulates caveolae in adipocytes.
|
Endocrinology
|
2014
|
0.80
|
|
62
|
Short- and long-term insulin-like effects of monoamine oxidases and semicarbazide-sensitive amine oxidase substrates in cultured adipocytes.
|
Metabolism
|
2006
|
0.80
|
|
63
|
Glucose handling in streptozotocin-induced diabetic rats is improved by tyramine but not by the amine oxidase inhibitor semicarbazide.
|
Eur J Pharmacol
|
2005
|
0.80
|
|
64
|
Apelin stimulates both cholecystokinin and glucagon-like peptide 1 secretions in vitro and in vivo in rodents.
|
Peptides
|
2013
|
0.79
|
|
65
|
Sensitivity of cardiac carnitine palmitoyltransferase to malonyl-CoA is regulated by leptin: similarities with a model of endogenous hyperleptinemia.
|
Endocrinology
|
2010
|
0.79
|
|
66
|
Pro-fibrotic activity of lysophosphatidic acid in adipose tissue: in vivo and in vitro evidence.
|
Biochim Biophys Acta
|
2013
|
0.77
|
|
67
|
Effects of dietary eicosapentaenoic acid (EPA) supplementation in high-fat fed mice on lipid metabolism and apelin/APJ system in skeletal muscle.
|
PLoS One
|
2013
|
0.77
|
|
68
|
The imidazoline I2-site ligands BU 224 and 2-BFI inhibit MAO-A and MAO-B activities, hydrogen peroxide production, and lipolysis in rodent and human adipocytes.
|
Eur J Pharmacol
|
2006
|
0.77
|
|
69
|
SSAO substrates exhibiting insulin-like effects in adipocytes as a promising treatment option for metabolic disorders.
|
Future Med Chem
|
2010
|
0.76
|
|
70
|
The apelinergic system: sexual dimorphism and tissue-specific modulations by obesity and insulin resistance in female mice.
|
Peptides
|
2013
|
0.76
|
|
71
|
Benzylamine antihyperglycemic effect is abolished by AOC3 gene invalidation in mice but not rescued by semicarbazide-sensitive amine oxidase expression under the control of aP2 promoter.
|
J Physiol Biochem
|
2012
|
0.76
|
|
72
|
Benzylamine exhibits insulin-like effects on glucose disposal, glucose transport, and fat cell lipolysis in rabbits and diabetic mice.
|
J Pharmacol Exp Ther
|
2004
|
0.75
|
|
73
|
Prenatal fasudil exposure alleviates fetal growth but programs hyperphagia and overweight in the adult male rat.
|
Eur J Pharmacol
|
2012
|
0.75
|
|
74
|
Corrigendum: Matrix metalloproteinase 11 protects from diabesity and promotes metabolic switch.
|
Sci Rep
|
2016
|
0.75
|
|
75
|
Influence of secreted factors from human adipose tissue on glucose utilization and proinflammatory reaction.
|
J Physiol Biochem
|
2013
|
0.75
|
|
76
|
Maternal hypertension induces tissue-specific modulations of the apelinergic system in the fetoplacental unit in rat.
|
Peptides
|
2012
|
0.75
|