| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
ASF/SF2-regulated CaMKIIdelta alternative splicing temporally reprograms excitation-contraction coupling in cardiac muscle.
|
Cell
|
2005
|
3.96
|
|
2
|
High basal protein kinase A-dependent phosphorylation drives rhythmic internal Ca2+ store oscillations and spontaneous beating of cardiac pacemaker cells.
|
Circ Res
|
2006
|
3.42
|
|
3
|
Linkage of beta1-adrenergic stimulation to apoptotic heart cell death through protein kinase A-independent activation of Ca2+/calmodulin kinase II.
|
J Clin Invest
|
2003
|
3.15
|
|
4
|
Dysregulation of HSG triggers vascular proliferative disorders.
|
Nat Cell Biol
|
2004
|
2.75
|
|
5
|
MG53 constitutes a primary determinant of cardiac ischemic preconditioning.
|
Circulation
|
2010
|
2.35
|
|
6
|
Recombinant MG53 protein modulates therapeutic cell membrane repair in treatment of muscular dystrophy.
|
Sci Transl Med
|
2012
|
2.27
|
|
7
|
Ca2+/calmodulin kinase II-dependent phosphorylation of ryanodine receptors suppresses Ca2+ sparks and Ca2+ waves in cardiac myocytes.
|
Circ Res
|
2007
|
1.98
|
|
8
|
Phosphoproteome analysis of cardiomyocytes subjected to beta-adrenergic stimulation: identification and characterization of a cardiac heat shock protein p20.
|
Circ Res
|
2003
|
1.98
|
|
9
|
Dilated cardiomyopathy caused by tissue-specific ablation of SC35 in the heart.
|
EMBO J
|
2004
|
1.88
|
|
10
|
Calmodulin kinase II inhibition protects against myocardial cell apoptosis in vivo.
|
Am J Physiol Heart Circ Physiol
|
2006
|
1.86
|
|
11
|
Sustained beta1-adrenergic stimulation modulates cardiac contractility by Ca2+/calmodulin kinase signaling pathway.
|
Circ Res
|
2004
|
1.85
|
|
12
|
Stereochemistry of an agonist determines coupling preference of beta2-adrenoceptor to different G proteins in cardiomyocytes.
|
Mol Pharmacol
|
2008
|
1.78
|
|
13
|
Comparative molecular field analysis of the binding of the stereoisomers of fenoterol and fenoterol derivatives to the beta2 adrenergic receptor.
|
J Med Chem
|
2007
|
1.77
|
|
14
|
Cardioprotection of ischemia/reperfusion injury by cholesterol-dependent MG53-mediated membrane repair.
|
Circ Res
|
2010
|
1.74
|
|
15
|
Activation of CaMKIIdeltaC is a common intermediate of diverse death stimuli-induced heart muscle cell apoptosis.
|
J Biol Chem
|
2007
|
1.61
|
|
16
|
Beta 1/beta 2-adrenergic receptor heterodimerization regulates beta 2-adrenergic receptor internalization and ERK signaling efficacy.
|
J Biol Chem
|
2002
|
1.59
|
|
17
|
Mitofusin-2 is a major determinant of oxidative stress-mediated heart muscle cell apoptosis.
|
J Biol Chem
|
2007
|
1.50
|
|
18
|
Mitofusin 2 triggers vascular smooth muscle cell apoptosis via mitochondrial death pathway.
|
Circ Res
|
2007
|
1.39
|
|
19
|
Central role of E3 ubiquitin ligase MG53 in insulin resistance and metabolic disorders.
|
Nature
|
2013
|
1.35
|
|
20
|
p38 Mitogen-activated protein kinase mediates a negative inotropic effect in cardiac myocytes.
|
Circ Res
|
2002
|
1.34
|
|
21
|
Emerging concepts and therapeutic implications of beta-adrenergic receptor subtype signaling.
|
Pharmacol Ther
|
2005
|
1.32
|
|
22
|
Phosphatidylinositol 3-kinase functionally compartmentalizes the concurrent G(s) signaling during beta2-adrenergic stimulation.
|
Circ Res
|
2002
|
1.24
|
|
23
|
Pak1 as a novel therapeutic target for antihypertrophic treatment in the heart.
|
Circulation
|
2011
|
1.18
|
|
24
|
Cardioprotection by CaMKII-deltaB is mediated by phosphorylation of heat shock factor 1 and subsequent expression of inducible heat shock protein 70.
|
Circ Res
|
2009
|
1.18
|
|
25
|
Heterodimerization of beta1- and beta2-adrenergic receptor subtypes optimizes beta-adrenergic modulation of cardiac contractility.
|
Circ Res
|
2005
|
1.17
|
|
26
|
The enigma of beta2-adrenergic receptor Gi signaling in the heart: the good, the bad, and the ugly.
|
Circ Res
|
2005
|
1.15
|
|
27
|
Enantioselective separation and online affinity chromatographic characterization of R,R- and S,S-fenoterol.
|
Chirality
|
2006
|
1.14
|
|
28
|
Nuclear Ca2+ sparks and waves mediated by inositol 1,4,5-trisphosphate receptors in neonatal rat cardiomyocytes.
|
Cell Calcium
|
2007
|
1.14
|
|
29
|
Cross-talk of opioid peptide receptor and beta-adrenergic receptor signalling in the heart.
|
Cardiovasc Res
|
2004
|
1.11
|
|
30
|
Comparative molecular field analysis of fenoterol derivatives: A platform towards highly selective and effective beta(2)-adrenergic receptor agonists.
|
Bioorg Med Chem
|
2009
|
1.09
|
|
31
|
MG53 participates in ischaemic postconditioning through the RISK signalling pathway.
|
Cardiovasc Res
|
2011
|
1.09
|
|
32
|
Ca(2+) signaling in cardiac myocytes overexpressing the alpha(1) subunit of L-type Ca(2+) channel.
|
Circ Res
|
2002
|
1.02
|
|
33
|
Gi-biased β2AR signaling links GRK2 upregulation to heart failure.
|
Circ Res
|
2011
|
1.01
|
|
34
|
G-protein-coupled receptor chromatographic stationary phases. 2. Ligand-induced conformational mobility in an immobilized beta2-adrenergic receptor.
|
Anal Chem
|
2004
|
1.00
|
|
35
|
RGS2 is a primary terminator of β₂-adrenergic receptor-mediated G(i) signaling.
|
J Mol Cell Cardiol
|
2011
|
0.98
|
|
36
|
Phosphatidylinositol 3-kinase offsets cAMP-mediated positive inotropic effect via inhibiting Ca2+ influx in cardiomyocytes.
|
Circ Res
|
2004
|
0.96
|
|
37
|
Dual site phospholamban phosphorylation and its physiological relevance in the heart.
|
Trends Cardiovasc Med
|
2002
|
0.94
|
|
38
|
Deregulation of RGS2 in cardiovascular diseases.
|
Front Biosci (Schol Ed)
|
2010
|
0.92
|
|
39
|
A novel immunomodulator, FTY-720 reverses existing cardiac hypertrophy and fibrosis from pressure overload by targeting NFAT (nuclear factor of activated T-cells) signaling and periostin.
|
Circ Heart Fail
|
2013
|
0.91
|
|
40
|
Activation of (Na+ + K+)-ATPase modulates cardiac L-type Ca2+ channel function.
|
Mol Pharmacol
|
2009
|
0.90
|
|
41
|
Intracellular acidosis-activated p38 MAPK signaling and its essential role in cardiomyocyte hypoxic injury.
|
FASEB J
|
2004
|
0.89
|
|
42
|
Receptor interacting protein 3 suppresses vascular smooth muscle cell growth by inhibition of the phosphoinositide 3-kinase-Akt axis.
|
J Biol Chem
|
2009
|
0.88
|
|
43
|
The effect of stereochemistry on the thermodynamic characteristics of the binding of fenoterol stereoisomers to the beta(2)-adrenoceptor.
|
Biochem Pharmacol
|
2010
|
0.86
|
|
44
|
Rad GTPase induces cardiomyocyte apoptosis through the activation of p38 mitogen-activated protein kinase.
|
Biochem Biophys Res Commun
|
2011
|
0.85
|
|
45
|
MCC-134, a single pharmacophore, opens surface ATP-sensitive potassium channels, blocks mitochondrial ATP-sensitive potassium channels, and suppresses preconditioning.
|
Circulation
|
2003
|
0.84
|
|
46
|
Serine496 of β2 subunit of L-type Ca2+ channel participates in molecular crosstalk between activation of (Na++K+)-ATPase and the channel.
|
Biochem Biophys Res Commun
|
2010
|
0.84
|
|
47
|
Distinct beta-adrenergic receptor subtype signaling in the heart and their pathophysiological relevance.
|
Sheng Li Xue Bao
|
2004
|
0.83
|
|
48
|
Calmodulin regulation of excitation-contraction coupling in cardiac myocytes.
|
Circ Res
|
2003
|
0.83
|
|
49
|
Role of mitofusin 2 in cardiovascular oxidative injury.
|
J Mol Med (Berl)
|
2010
|
0.81
|
|
50
|
The third intracellular loop and the carboxyl terminus of beta2-adrenergic receptor confer spontaneous activity of the receptor.
|
Mol Pharmacol
|
2003
|
0.80
|
|
51
|
Cardiomyocyte life-death decisions in response to chronic β-adrenergic signaling.
|
Circ Res
|
2013
|
0.79
|
|
52
|
Infarction induced myocardial apoptosis and ARC activation.
|
J Surg Res
|
2009
|
0.79
|
|
53
|
AMPK and TNF-alpha at the crossroad of cell survival and death in ischaemic heart.
|
Cardiovasc Res
|
2009
|
0.78
|
|
54
|
Mechanistic distinction between activation and inhibition of (Na(+)+K(+))-ATPase-mediated Ca2+ influx in cardiomyocytes.
|
Biochem Biophys Res Commun
|
2011
|
0.78
|
|
55
|
Different regulation of ERK1/2 activation by beta-adrenergic receptor subtypes in adult mouse cardiomyocytes.
|
Heart Lung Circ
|
2004
|
0.77
|
|
56
|
Effect of fenoterol stereochemistry on the β2 adrenergic receptor system: ligand-directed chiral recognition.
|
Chirality
|
2011
|
0.77
|
|
57
|
Expression of the Pokemon proto-oncogene in nasopharyngeal carcinoma cell lines and tissues.
|
Asian Pac J Cancer Prev
|
2013
|
0.77
|
|
58
|
Acidosis-induced p38 MAPK activation and its implication in regulation of cardiac contractility.
|
Acta Pharmacol Sin
|
2004
|
0.76
|
|
59
|
mTOR: good, bad, or ugly?
|
Cardiovasc Res
|
2012
|
0.75
|
|
60
|
HDAC6-mediated acetylation of lipid droplet-binding protein CIDEC regulates fat-induced lipid storage.
|
J Clin Invest
|
2017
|
0.75
|
|
61
|
Myocardial glycogen dynamics: new perspectives on disease mechanisms.
|
Clin Exp Pharmacol Physiol
|
2015
|
0.75
|
|
62
|
Molecular pathological study of the human nasopharyngeal carcinoma CNE3 cell line.
|
Oncol Lett
|
2013
|
0.75
|
|
63
|
Kinase activity-independent anchoring function of protein kinase C-{delta}. Focus on "Protein kinase C-{delta} regulates the subcellular localization of Shc in H2O2-treated cardiomyocytes".
|
Am J Physiol Cell Physiol
|
2010
|
0.75
|
|
64
|
β-adrenergic receptor subtype signaling in the heart: from bench to the bedside.
|
Curr Top Membr
|
2011
|
0.75
|
|
65
|
Bioimaging for cardiometabolic translational medicine: from cellular messengers to organism function.
|
J Mol Med (Berl)
|
2013
|
0.75
|