Kenji Sakimura

Author PubWeight™ 81.16‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The endocannabinoid 2-arachidonoylglycerol produced by diacylglycerol lipase alpha mediates retrograde suppression of synaptic transmission. Neuron 2010 3.28
2 Inverse synaptic tagging of inactive synapses via dynamic interaction of Arc/Arg3.1 with CaMKIIβ. Cell 2012 2.14
3 Trans-synaptic interaction of GluRdelta2 and Neurexin through Cbln1 mediates synapse formation in the cerebellum. Cell 2010 2.09
4 Distinct modes of AMPA receptor suppression at developing synapses by GluN2A and GluN2B: single-cell NMDA receptor subunit deletion in vivo. Neuron 2011 1.78
5 Serine racemase is predominantly localized in neurons in mouse brain. J Comp Neurol 2008 1.57
6 Cdk5/p35 is required for motor coordination and cerebellar plasticity. J Neurochem 2014 1.42
7 Identification of arylsulfonamides as Aquaporin 4 inhibitors. Bioorg Med Chem Lett 2006 1.41
8 Functional coupling between mGluR1 and Cav3.1 T-type calcium channels contributes to parallel fiber-induced fast calcium signaling within Purkinje cell dendritic spines. J Neurosci 2009 1.36
9 Conditional gene targeting on the pure C57BL/6 genetic background. Neurosci Res 2007 1.36
10 Clinical features of neuromyelitis optica in a large Japanese cohort: comparison between phenotypes. J Neurol Neurosurg Psychiatry 2011 1.32
11 Spatial diversity in gene expression for VDCCgamma subunit family in developing and adult mouse brains. Neurosci Res 2005 1.25
12 Abundant distribution of TARP gamma-8 in synaptic and extrasynaptic surface of hippocampal neurons and its major role in AMPA receptor expression on spines and dendrites. Eur J Neurosci 2006 1.24
13 Unique inhibitory synapse with particularly rich endocannabinoid signaling machinery on pyramidal neurons in basal amygdaloid nucleus. Proc Natl Acad Sci U S A 2011 1.23
14 A novel action of stargazin as an enhancer of AMPA receptor activity. Neurosci Res 2004 1.23
15 NMDA receptor GluN2B (GluR epsilon 2/NR2B) subunit is crucial for channel function, postsynaptic macromolecular organization, and actin cytoskeleton at hippocampal CA3 synapses. J Neurosci 2009 1.20
16 Distal extension of climbing fiber territory and multiple innervation caused by aberrant wiring to adjacent spiny branchlets in cerebellar Purkinje cells lacking glutamate receptor delta 2. J Neurosci 2002 1.16
17 Target-cell-specific left-right asymmetry of NMDA receptor content in schaffer collateral synapses in epsilon1/NR2A knock-out mice. J Neurosci 2005 1.15
18 Motor neuron-specific disruption of proteasomes, but not autophagy, replicates amyotrophic lateral sclerosis. J Biol Chem 2012 1.15
19 Suppression of synaptic plasticity by cerebrospinal fluid from anti-NMDA receptor encephalitis patients. Neurobiol Dis 2011 1.13
20 Reduced sensitivity to ketamine and pentobarbital in mice lacking the N-methyl-D-aspartate receptor GluRepsilon1 subunit. Anesth Analg 2004 1.12
21 Subtypes of GABAergic neurons project axons in the neocortex. Front Neuroanat 2009 1.12
22 Control of synaptic connection by glutamate receptor delta2 in the adult cerebellum. J Neurosci 2005 1.10
23 Mutation of alpha1G T-type calcium channels in mice does not change anesthetic requirements for loss of the righting reflex and minimum alveolar concentration but delays the onset of anesthetic induction. Anesthesiology 2007 1.09
24 Basic leucine zipper transcription factor, ATF-like (BATF) regulates epigenetically and energetically effector CD8 T-cell differentiation via Sirt1 expression. Proc Natl Acad Sci U S A 2011 1.08
25 Activity-dependent glial swelling is impaired in aquaporin-4 knockout mice. Neurosci Res 2009 1.06
26 Roles of nitric oxide as a vasodilator in neurovascular coupling of mouse somatosensory cortex. Neurosci Res 2007 1.05
27 Molecular and morphological configuration for 2-arachidonoylglycerol-mediated retrograde signaling at mossy cell-granule cell synapses in the dentate gyrus. J Neurosci 2011 1.05
28 TARPs gamma-2 and gamma-7 are essential for AMPA receptor expression in the cerebellum. Eur J Neurosci 2010 1.03
29 LPA4 regulates blood and lymphatic vessel formation during mouse embryogenesis. Blood 2010 1.03
30 NG2 proteoglycan promotes tumor vascularization via integrin-dependent effects on pericyte function. Angiogenesis 2013 1.03
31 Calpain 8/nCL-2 and calpain 9/nCL-4 constitute an active protease complex, G-calpain, involved in gastric mucosal defense. PLoS Genet 2010 1.03
32 Cav2.1 in cerebellar Purkinje cells regulates competitive excitatory synaptic wiring, cell survival, and cerebellar biochemical compartmentalization. J Neurosci 2012 1.01
33 Postsynaptic P/Q-type Ca2+ channel in Purkinje cell mediates synaptic competition and elimination in developing cerebellum. Proc Natl Acad Sci U S A 2011 1.00
34 Chondroitin sulphate N-acetylgalactosaminyl-transferase-1 inhibits recovery from neural injury. Nat Commun 2013 1.00
35 GABAergic inhibition regulates developmental synapse elimination in the cerebellum. Neuron 2012 0.96
36 Chondroitin sulfate N-acetylgalactosaminyltransferase-1 is required for normal cartilage development. Biochem J 2010 0.95
37 NMDA receptor GluRepsilon/NR2 subunits are essential for postsynaptic localization and protein stability of GluRzeta1/NR1 subunit. J Neurosci 2004 0.94
38 Glutamate receptor δ2 is essential for input pathway-dependent regulation of synaptic AMPAR contents in cerebellar Purkinje cells. J Neurosci 2011 0.94
39 Synapse type-independent degradation of the endocannabinoid 2-arachidonoylglycerol after retrograde synaptic suppression. Proc Natl Acad Sci U S A 2012 0.93
40 Ablation of NG2 proteoglycan leads to deficits in brown fat function and to adult onset obesity. PLoS One 2012 0.92
41 Calcium-dependent regulation of climbing fibre synapse elimination during postnatal cerebellar development. J Physiol 2013 0.91
42 Enhancement of both long-term depression induction and optokinetic response adaptation in mice lacking delphilin. PLoS One 2008 0.91
43 Nitric oxide (NO) serves as a retrograde messenger to activate neuronal NO synthase in the spinal cord via NMDA receptors. Nitric Oxide 2007 0.90
44 Cysteinyl leukotriene 2 receptor-mediated vascular permeability via transendothelial vesicle transport. FASEB J 2008 0.89
45 Effects of FAK ablation on cerebellar foliation, Bergmann glia positioning and climbing fiber territory on Purkinje cells. Eur J Neurosci 2008 0.89
46 T-type calcium channel antagonists suppress tremor in two mouse models of essential tremor. Neuropharmacology 2010 0.88
47 Regulation of long-term depression and climbing fiber territory by glutamate receptor delta2 at parallel fiber synapses through its C-terminal domain in cerebellar Purkinje cells. J Neurosci 2007 0.88
48 NG2 cells are uniformly distributed and NG2 is not required for barrel formation in the somatosensory cortex. Mol Cell Neurosci 2011 0.87
49 Effects of ketamine on acute somatic nociception in wild-type and N-methyl-D-aspartate (NMDA) receptor epsilon1 subunit knockout mice. Neuropharmacology 2006 0.87
50 The NR3B subunit does not alter the anesthetic sensitivities of recombinant N-methyl-D-aspartate receptors. Anesth Analg 2005 0.87
51 Sustained brain-derived neurotrophic factor up-regulation and sensorimotor gating abnormality induced by postnatal exposure to phencyclidine: comparison with adult treatment. J Neurochem 2006 0.87
52 In vitro generation of HSC-like cells from murine ESCs/iPSCs by enforced expression of LIM-homeobox transcription factor Lhx2. Blood 2011 0.87
53 Tangential migration and proliferation of intermediate progenitors of GABAergic neurons in the mouse telencephalon. Development 2011 0.86
54 Ablation of glutamate receptor GluRδ2 in adult Purkinje cells causes multiple innervation of climbing fibers by inducing aberrant invasion to parallel fiber innervation territory. J Neurosci 2010 0.86
55 Mouse liaison for integrative brain research. Neurosci Res 2007 0.85
56 Ablation of NMDA receptors enhances the excitability of hippocampal CA3 neurons. PLoS One 2009 0.84
57 Expression and possible role of creatine transporter in the brain and at the blood-cerebrospinal fluid barrier as a transporting protein of guanidinoacetate, an endogenous convulsant. J Neurochem 2008 0.83
58 NMDA receptor subunits have different roles in NMDA-induced neurotoxicity in the retina. Mol Brain 2013 0.83
59 Reduced immobilizing properties of isoflurane and nitrous oxide in mutant mice lacking the N-methyl-D-aspartate receptor GluR(epsilon)1 subunit are caused by the secondary effects of gene knockout. Anesth Analg 2009 0.82
60 Unaltered pain-related behavior in mice lacking NMDA receptor GluRepsilon 1 subunit. Neurosci Res 2003 0.82
61 Disruption of cerebellar microzonal organization in GluD2 (GluRδ2) knockout mouse. Front Neural Circuits 2013 0.81
62 Diacylglycerol lipase α manipulation reveals developmental roles for intercellular endocannabinoid signaling. Sci Rep 2013 0.81
63 Ionotropic glutamate receptor AMPA 1 is associated with ovulation rate. PLoS One 2010 0.81
64 A novel form of memory for auditory fear conditioning at a low-intensity unconditioned stimulus. PLoS One 2009 0.81
65 Neuronal protease-activated receptor 1 drives synaptic retrograde signaling mediated by the endocannabinoid 2-arachidonoylglycerol. J Neurosci 2011 0.81
66 Organotypic coculture preparation for the study of developmental synapse elimination in mammalian brain. J Neurosci 2012 0.81
67 Functional characterization of a novel missense CLCN5 mutation causing alterations in proximal tubular endocytic machinery in Dent's disease. Nephron Physiol 2007 0.80
68 Heterogeneous presynaptic distribution of monoacylglycerol lipase, a multipotent regulator of nociceptive circuits in the mouse spinal cord. Eur J Neurosci 2014 0.80
69 Spike timing-dependent selective strengthening of single climbing fibre inputs to Purkinje cells during cerebellar development. Nat Commun 2013 0.80
70 Point mutation in syntaxin-1A causes abnormal vesicle recycling, behaviors, and short term plasticity. J Biol Chem 2013 0.79
71 Visualization of corticotropin-releasing factor neurons by fluorescent proteins in the mouse brain and characterization of labeled neurons in the paraventricular nucleus of the hypothalamus. Endocrinology 2014 0.79
72 Signal pathways coupled to activation of neuronal nitric oxide synthase in the spinal cord by nociceptin/orphanin FQ. Neuropharmacology 2007 0.79
73 Cloning and characterization of porcine common gamma chain gene. J Interferon Cytokine Res 2003 0.78
74 Role of the internal Shank-binding segment of glutamate receptor delta2 in synaptic localization and cerebellar functions. Neurosci Lett 2008 0.77
75 The endocannabinoid 2-arachidonoylglycerol negatively regulates habituation by suppressing excitatory recurrent network activity and reducing long-term potentiation in the dentate gyrus. J Neurosci 2013 0.77
76 Effect of agmatine on heteromeric N-methyl-D-aspartate receptor channels. Neurosci Res 2005 0.77
77 Characterization of N-methyl-D-aspartate receptor subunits involved in acute ammonia toxicity. Neurochem Int 2004 0.77
78 Cell of origin in radiation-induced premalignant thymocytes with differentiation capability in mice conditionally losing one Bcl11b allele. Cancer Sci 2013 0.76
79 Microglial phospholipase D4 deficiency influences myelination during brain development. Proc Jpn Acad Ser B Phys Biol Sci 2016 0.75
80 Increased brain monoaminergic tone after the NMDA receptor GluN2A subunit gene knockout is responsible for resistance to the hypnotic effect of nitrous oxide. Eur J Pharmacol 2012 0.75
81 Characterization of N-methyl-D-aspartate receptor subunits responsible for postoperative pain. Eur J Pharmacol 2004 0.75
82 [Elucidation of anesthetic and analgesic effects of ketamine using NMDA receptor epsilon 1 subunit-deficient mice]. Masui 2006 0.75