Published in Am J Physiol Lung Cell Mol Physiol on August 06, 2010
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Control of HIF-1{alpha} and vascular signaling in fetal lung involves cross talk between mTORC1 and the FGF-10/FGFR2b/Spry2 airway branching periodicity clock. Am J Physiol Lung Cell Mol Physiol (2010) 1.63
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Identification of a novel hypoxia-inducible factor 1-responsive gene, RTP801, involved in apoptosis. Mol Cell Biol (2002) 3.30
Smad3 deficiency attenuates bleomycin-induced pulmonary fibrosis in mice. Am J Physiol Lung Cell Mol Physiol (2002) 2.83
Conditional switching of VEGF provides new insights into adult neovascularization and pro-angiogenic therapy. EMBO J (2002) 2.74
TGF-beta activates Erk MAP kinase signalling through direct phosphorylation of ShcA. EMBO J (2007) 2.57
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Reversible modulations of neuronal plasticity by VEGF. Proc Natl Acad Sci U S A (2011) 2.06
Uterine DCs are crucial for decidua formation during embryo implantation in mice. J Clin Invest (2008) 1.82
VEGF-A signaling through Flk-1 is a critical facilitator of early embryonic lung epithelial to endothelial crosstalk and branching morphogenesis. Dev Biol (2005) 1.81
Fgf10 dosage is critical for the amplification of epithelial cell progenitors and for the formation of multiple mesenchymal lineages during lung development. Dev Biol (2007) 1.74
Burkholderia cepacia-induced IL-8 gene expression in an alveolar epithelial cell line: signaling through CD14 and mitogen-activated protein kinase. Pediatr Res (2003) 1.74
Stem cells and cell therapies in lung biology and lung diseases. Proc Am Thorac Soc (2011) 1.66
Specific induction of tie1 promoter by disturbed flow in atherosclerosis-prone vascular niches and flow-obstructing pathologies. Circ Res (2003) 1.64
Differential role of FGF9 on epithelium and mesenchyme in mouse embryonic lung. Dev Biol (2006) 1.64
Eyes absent 1 (Eya1) is a critical coordinator of epithelial, mesenchymal and vascular morphogenesis in the mammalian lung. Dev Biol (2010) 1.59
Abnormal mouse lung alveolarization caused by Smad3 deficiency is a developmental antecedent of centrilobular emphysema. Am J Physiol Lung Cell Mol Physiol (2004) 1.56
miR-17 family of microRNAs controls FGF10-mediated embryonic lung epithelial branching morphogenesis through MAPK14 and STAT3 regulation of E-Cadherin distribution. Dev Biol (2009) 1.56
Fibrillin controls TGF-beta activation. Nat Genet (2003) 1.53
Transfer of the active form of transforming growth factor-beta 1 gene to newborn rat lung induces changes consistent with bronchopulmonary dysplasia. Am J Pathol (2003) 1.53
Lung development and adult lung diseases. Chest (2007) 1.47
Human amniotic fluid stem cells can integrate and differentiate into epithelial lung lineages. Stem Cells (2008) 1.46
Protective effect of human amniotic fluid stem cells in an immunodeficient mouse model of acute tubular necrosis. PLoS One (2010) 1.44
Transgenic system for conditional induction and rescue of chronic myocardial hibernation provides insights into genomic programs of hibernation. Proc Natl Acad Sci U S A (2007) 1.43
Isolation of a putative progenitor subpopulation of alveolar epithelial type 2 cells. Am J Physiol Lung Cell Mol Physiol (2003) 1.42
Activated pp60c-Src leads to elevated hypoxia-inducible factor (HIF)-1alpha expression under normoxia. J Biol Chem (2002) 1.42
Developmental biology: order in the lung. Nature (2008) 1.36
Blood vessels restrain pancreas branching, differentiation and growth. Development (2011) 1.35
Colonic atresia without mesenteric vascular occlusion. The role of the fibroblast growth factor 10 signaling pathway. J Pediatr Surg (2005) 1.28
Development, repair and fibrosis: what is common and why it matters. Respirology (2009) 1.24
Ero1-L alpha plays a key role in a HIF-1-mediated pathway to improve disulfide bond formation and VEGF secretion under hypoxia: implication for cancer. Oncogene (2005) 1.20
Contrasting expression of canonical Wnt signaling reporters TOPGAL, BATGAL and Axin2(LacZ) during murine lung development and repair. PLoS One (2011) 1.20
TACE is required for fetal murine cardiac development and modeling. Dev Biol (2003) 1.19
A perfusion-independent role of blood vessels in determining branching stereotypy of lung airways. Development (2011) 1.18
Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung. Dev Biol (2006) 1.15
On-site education of VEGF-recruited monocytes improves their performance as angiogenic and arteriogenic accessory cells. J Exp Med (2013) 1.14
Induction of vascular networks in adult organs: implications to proangiogenic therapy. Ann N Y Acad Sci (2003) 1.13
MIR-99a and MIR-99b modulate TGF-β induced epithelial to mesenchymal plasticity in normal murine mammary gland cells. PLoS One (2012) 1.13
Prenatal lung epithelial cell-specific abrogation of Alk3-bone morphogenetic protein signaling causes neonatal respiratory distress by disrupting distal airway formation. Am J Pathol (2008) 1.13
Congenital diaphragmatic hernia. Paediatr Respir Rev (2002) 1.13
Tracheal occlusion increases the rate of epithelial branching of embryonic mouse lung via the FGF10-FGFR2b-Sprouty2 pathway. Mech Dev (2007) 1.13
A role for Wnt signaling genes in the pathogenesis of impaired lung function in asthma. Am J Respir Crit Care Med (2009) 1.12
Fibroblast growth factor receptor 2 IIIb invalidation--a potential cause of familial duodenal atresia. J Pediatr Surg (2004) 1.11
Progressive pulmonary fibrosis is mediated by TGF-beta isoform 1 but not TGF-beta3. Int J Biochem Cell Biol (2007) 1.11
Overexpression of Smurf1 negatively regulates mouse embryonic lung branching morphogenesis by specifically reducing Smad1 and Smad5 proteins. Am J Physiol Lung Cell Mol Physiol (2004) 1.11
The transcription factors Grainyhead-like 2 and NK2-homeobox 1 form a regulatory loop that coordinates lung epithelial cell morphogenesis and differentiation. J Biol Chem (2012) 1.10
Smad3 signaling involved in pulmonary fibrosis and emphysema. Proc Am Thorac Soc (2006) 1.09
VEGF modulates early heart valve formation. Anat Rec A Discov Mol Cell Evol Biol (2003) 1.09
The human gamma-glutamyltransferase gene family. Hum Genet (2008) 1.08
Octreotide for treatment of chylothorax after repair of congenital diaphragmatic hernia. J Pediatr Surg (2003) 1.07
BMP4 activation and secretion are negatively regulated by an intracellular gremlin-BMP4 interaction. J Biol Chem (2006) 1.07
Prolonged blockade of VEGF family members does not cause identifiable damage to retinal neurons or vessels. J Cell Physiol (2008) 1.06
Neonatal endosurgical congenital diaphragmatic hernia repair: a systematic review and meta-analysis. Ann Surg (2010) 1.06
Making vascular networks in the adult: branching morphogenesis without a roadmap. Trends Cell Biol (2003) 1.05
Heparan sulfate phage display antibodies identify distinct epitopes with complex binding characteristics: insights into protein binding specificities. J Biol Chem (2009) 1.05
Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium. Development (2011) 1.04
Local retention versus systemic release of soluble VEGF receptor-1 are mediated by heparin-binding and regulated by heparanase. Circ Res (2011) 1.04
Adoptive transfer of induced-Treg cells effectively attenuates murine airway allergic inflammation. PLoS One (2012) 1.04
FGF10 controls the patterning of the tracheal cartilage rings via Shh. Development (2010) 1.03
The fibroblast growth factor pathway serves a regulatory role in proliferation and apoptosis in the pathogenesis of intestinal atresia. J Pediatr Surg (2006) 1.03
Explant culture of mouse embryonic whole lung, isolated epithelium, or mesenchyme under chemically defined conditions as a system to evaluate the molecular mechanism of branching morphogenesis and cellular differentiation. Methods Mol Biol (2010) 1.02
Overexpression of fibroblast growth factor-10 during both inflammatory and fibrotic phases attenuates bleomycin-induced pulmonary fibrosis in mice. Am J Respir Crit Care Med (2009) 1.01
Mechanical stretch promotes fetal type II epithelial cell differentiation via shedding of HB-EGF and TGF-alpha. J Physiol (2009) 1.01
TNF-alpha represses transcription of human Bone Morphogenetic Protein-4 in lung epithelial cells. Gene (2007) 1.00
Fibroblast growth factor 10 is required for survival and proliferation but not differentiation of intestinal epithelial progenitor cells during murine colon development. Dev Biol (2006) 1.00
Fibroblast growth factor 10 plays a causative role in the tracheal cartilage defects in a mouse model of Apert syndrome. Pediatr Res (2009) 1.00
Branching patterns emerge in a mathematical model of the dynamics of lung development. J Physiol (2013) 1.00
Regulation of mouse lung development by the extracellular calcium-sensing receptor, CaR. J Physiol (2008) 0.99
Tracheostomy--a 10-year experience from a UK pediatric surgical center. J Pediatr Surg (2007) 0.99
Injection of amniotic fluid stem cells delays progression of renal fibrosis. J Am Soc Nephrol (2012) 0.98
Human amniotic fluid as a potential new source of organ specific precursor cells for future regenerative medicine applications. J Urol (2010) 0.98
Sprouty2 downregulation plays a pivotal role in mediating crosstalk between TGF-beta1 signaling and EGF as well as FGF receptor tyrosine kinase-ERK pathways in mesenchymal cells. J Cell Physiol (2007) 0.97
VEGF is required for dendritogenesis of newly born olfactory bulb interneurons. Development (2010) 0.96
Spatial-temporal targeting of lung-specific mesenchyme by a Tbx4 enhancer. BMC Biol (2013) 0.95
Fibroblast growth factor-10 serves a regulatory role in duodenal development. J Pediatr Surg (2005) 0.95
A novel function for the protein tyrosine phosphatase Shp2 during lung branching morphogenesis. Dev Biol (2005) 0.95
State-of-the-Art Methods for Evaluation of Angiogenesis and Tissue Vascularization: A Scientific Statement From the American Heart Association. Circ Res (2015) 0.94
Delineating multiple functions of VEGF-A in the adult brain. Cell Mol Life Sci (2013) 0.94
Vascular endothelial growth factor and vascular homeostasis. Proc Am Thorac Soc (2011) 0.93
Sacrococcygeal teratoma--a 25-year experience in a UK regional center. J Pediatr Surg (2006) 0.92
Transient overexpression of Gremlin results in epithelial activation and reversible fibrosis in rat lungs. Am J Respir Cell Mol Biol (2010) 0.92
Can increased understanding of the role of lung development and aging drive new advances in chronic obstructive pulmonary disease? Proc Am Thorac Soc (2009) 0.91
A transgenic model for conditional induction and rescue of portal hypertension reveals a role of VEGF-mediated regulation of sinusoidal fenestrations. PLoS One (2011) 0.91
Knock-on effect of anthrax lethal toxin on macrophages potentiates cytotoxicity to endothelial cells. Microbes Infect (2004) 0.91
The milieu of damaged alveolar epithelial type 2 cells stimulates alveolar wound repair by endogenous and exogenous progenitors. Am J Respir Cell Mol Biol (2011) 0.90
Cell polarity and spindle orientation in the distal epithelium of embryonic lung. Dev Dyn (2011) 0.90
Functional analysis of the human Sprouty2 gene promoter. Gene (2003) 0.89
Six1 transcription factor is critical for coordination of epithelial, mesenchymal and vascular morphogenesis in the mammalian lung. Dev Biol (2011) 0.89
Metabolic homeostasis is maintained in myocardial hibernation by adaptive changes in the transcriptome and proteome. J Mol Cell Cardiol (2011) 0.88
Nitrofen inhibition of pulmonary growth and development occurs in the early embryonic mouse. J Pediatr Surg (2002) 0.88
Conditional hypovascularization and hypoxia in islets do not overtly influence adult β-cell mass or function. Diabetes (2013) 0.87
Spontaneous propagating calcium waves underpin airway peristalsis in embryonic rat lung. Am J Respir Cell Mol Biol (2005) 0.87
Smad1 expression and function during mouse embryonic lung branching morphogenesis. Am J Physiol Lung Cell Mol Physiol (2005) 0.87