Published in J Biomed Biotechnol on July 14, 2010
The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling. Bioinformatics (2005) 34.83
InterProScan--an integration platform for the signature-recognition methods in InterPro. Bioinformatics (2001) 28.35
SWISS-MODEL: An automated protein homology-modeling server. Nucleic Acids Res (2003) 25.86
The SWISS-MODEL Repository and associated resources. Nucleic Acids Res (2008) 11.61
VERIFY3D: assessment of protein models with three-dimensional profiles. Methods Enzymol (1997) 6.71
Assessing protein structures with a non-local atomic interaction energy. J Mol Biol (1998) 4.42
Engineering polydactyl zinc-finger transcription factors. Nat Biotechnol (2002) 4.40
Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases. Nucleic Acids Res (2006) 3.95
Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions. Activation of vascular endothelial growth factor A. J Biol Chem (2001) 3.38
Adenovirus-mediated heme oxygenase-1 gene transfer inhibits the development of atherosclerosis in apolipoprotein E-deficient mice. Circulation (2001) 2.32
Heme oxygenase-1 inhibits atherosclerotic lesion formation in ldl-receptor knockout mice. Circ Res (2001) 2.14
Heme oxygenase-1: the "emerging molecule" has arrived. Am J Respir Cell Mol Biol (2002) 2.12
Heme oxygenase-1 inhibits angiotensin II-induced cardiac hypertrophy in vitro and in vivo. Circulation (2004) 1.94
Transcriptional regulation of the heme oxygenase-1 gene via the stress response element pathway. Curr Pharm Des (2003) 1.74
Rapid, high-throughput engineering of sequence-specific zinc finger DNA-binding proteins. Methods Enzymol (2001) 1.49
Oxidized phospholipids induce expression of human heme oxygenase-1 involving activation of cAMP-responsive element-binding protein. J Biol Chem (2003) 1.49
Fingers reach for the genome. Nat Biotechnol (2003) 1.48
Exploring strategies for the design of artificial transcription factors: targeting sites proximal to known regulatory regions for the induction of gamma-globin expression and the treatment of sickle cell disease. J Biol Chem (2004) 1.30
Rational design of artificial zinc-finger proteins using a nondegenerate recognition code table. Biochemistry (2002) 1.26
Increased serum ferritin is common in men with essential hypertension. J Hypertens (2002) 1.25
Zinc-finger-based artificial transcription factors and their applications. Adv Drug Deliv Rev (2009) 1.25
Vascular heme oxygenase-1 induction suppresses microvascular thrombus formation in vivo. Arterioscler Thromb Vasc Biol (2004) 1.11
Regulation of the endogenous VEGF-A gene by exogenous designed regulatory proteins. Proc Natl Acad Sci U S A (2004) 1.04
Bladder carcinoma cell line ECV304 is not a model system for endothelial cells. In Vitro Cell Dev Biol Anim (2002) 1.02
Cardioselective overexpression of HO-1 prevents I/R-induced cardiac dysfunction and apoptosis. Am J Physiol Heart Circ Physiol (2002) 1.01
Induction of heme oxygenase-1 and stimulation of cGMP production by hemin in aortic tissues from hypertensive rats. Blood (2002) 0.95
Targeting the transcriptional machinery with unique artificial transcriptional activators. J Am Chem Soc (2003) 0.87
Design of a zinc finger protein binding a sequence upstream of the A20 gene. BMC Biotechnol (2008) 0.77
MTDH activation by 8q22 genomic gain promotes chemoresistance and metastasis of poor-prognosis breast cancer. Cancer Cell (2009) 4.47
Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization. Nat Med (2011) 3.82
VCAM-1 promotes osteolytic expansion of indolent bone micrometastasis of breast cancer by engaging α4β1-positive osteoclast progenitors. Cancer Cell (2011) 3.23
Elf5 inhibits the epithelial-mesenchymal transition in mammary gland development and breast cancer metastasis by transcriptionally repressing Snail2. Nat Cell Biol (2012) 2.46
The multifaceted role of MTDH/AEG-1 in cancer progression. Clin Cancer Res (2009) 1.89
Transcriptional network analysis identifies BACH1 as a master regulator of breast cancer bone metastasis. J Biol Chem (2012) 1.58
ΔNp63 versatilely regulates a Broad NF-κB gene program and promotes squamous epithelial proliferation, migration, and inflammation. Cancer Res (2011) 1.52
MicroRNA-145 regulates chondrogenic differentiation of mesenchymal stem cells by targeting Sox9. PLoS One (2011) 1.47
Procedural arrhythmia termination and long-term single-procedure clinical outcome in patients with non-paroxysmal atrial fibrillation. J Cardiovasc Electrophysiol (2013) 1.45
Elf5 regulates mammary gland stem/progenitor cell fate by influencing notch signaling. Stem Cells (2012) 1.37
Identification of staphylococcal nuclease domain-containing 1 (SND1) as a Metadherin-interacting protein with metastasis-promoting functions. J Biol Chem (2011) 1.33
In vivo dynamics and distinct functions of hypoxia in primary tumor growth and organotropic metastasis of breast cancer. Cancer Res (2010) 1.31
Squamous cell carcinoma cell aggregates escape suspension-induced, p53-mediated anoikis: fibronectin and integrin alphav mediate survival signals through focal adhesion kinase. J Biol Chem (2004) 1.21
Rescue of ATP7B function in hepatocyte-like cells from Wilson's disease induced pluripotent stem cells using gene therapy or the chaperone drug curcumin. Hum Mol Genet (2011) 1.20
CK2 modulation of NF-kappaB, TP53, and the malignant phenotype in head and neck cancer by anti-CK2 oligonucleotides in vitro or in vivo via sub-50-nm nanocapsules. Clin Cancer Res (2010) 1.16
Attenuated transforming growth factor beta signaling promotes nuclear factor-kappaB activation in head and neck cancer. Cancer Res (2009) 1.11
Immunomodulatory effect of human umbilical cord Wharton's jelly-derived mesenchymal stem cells on lymphocytes. Cell Immunol (2011) 1.08
Overexpression of mtlD gene in transgenic Populus tomentosa improves salt tolerance through accumulation of mannitol. Tree Physiol (2005) 1.03
Occult HBV infection in anti-HBs-positive young adults after neonatal HB vaccination. Vaccine (2010) 1.02
The p53 homologue DeltaNp63alpha interacts with the nuclear factor-kappaB pathway to modulate epithelial cell growth. Cancer Res (2008) 1.01
Compositional modulation in In(x)Ga(1-x)N: TEM and X-ray studies. J Electron Microsc (Tokyo) (2005) 0.97
Development of anti-atherosclerotic tissue-engineered blood vessel by A20-regulated endothelial progenitor cells seeding decellularized vascular matrix. Biomaterials (2008) 0.96
Metadherin as a link between metastasis and chemoresistance. Cell Cycle (2009) 0.95
Joint influences of aerodynamic flow field and aerodynamic heating of the dome on imaging quality degradation of airborne optical systems. Appl Opt (2012) 0.95
Hepatitis B virus induces IL-23 production in antigen presenting cells and causes liver damage via the IL-23/IL-17 axis. PLoS Pathog (2013) 0.94
Altered angiotensin-converting enzyme and its effects on the brain in a rat model of Alzheimer disease. Chin Med J (Engl) (2008) 0.92
Activated IL-23/IL-17 pathway closely correlates with increased Foxp3 expression in livers of chronic hepatitis B patients. BMC Immunol (2011) 0.92
TLR8 agonists stimulate newly recruited monocyte-derived cells into potent APCs that enhance HBsAg immunogenicity. Vaccine (2010) 0.91
Association between microalbuminuria and subclinical atherosclerosis evaluated by carotid artery intima-media in elderly patients with normal renal function. BMC Nephrol (2012) 0.90
Protein tyrosine phosphatase UBASH3B is overexpressed in triple-negative breast cancer and promotes invasion and metastasis. Proc Natl Acad Sci U S A (2013) 0.90
NtCP56, a new cysteine protease in Nicotiana tabacum L., involved in pollen grain development. J Exp Bot (2009) 0.89
Slug inhibition upregulates radiation-induced PUMA activity leading to apoptosis in cholangiocarcinomas. Med Oncol (2010) 0.88
The apple WD40 protein MdTTG1 interacts with bHLH but not MYB proteins to regulate anthocyanin accumulation. J Plant Physiol (2012) 0.88
Effects of telbivudine treatment on the circulating CD4⁺ T-cell subpopulations in chronic hepatitis B patients. Mediators Inflamm (2012) 0.88
Insights into the catalytic mechanism of 16S rRNA methyltransferase RsmE (m³U1498) from crystal and solution structures. J Mol Biol (2012) 0.87
Exon skipping of AGAMOUS homolog PrseAG in developing double flowers of Prunus lannesiana (Rosaceae). Plant Cell Rep (2012) 0.85
Phase I/II trial of non-cytotoxic suramin in combination with weekly paclitaxel in metastatic breast cancer treated with prior taxanes. Cancer Chemother Pharmacol (2012) 0.85
A novel splice variant of FR4 predominantly expressed in CD4+CD25+ regulatory T cells. Immunol Invest (2009) 0.85
Increased intratumoral interleukin 22 levels and frequencies of interleukin 22-producing CD4+ T cells correlate with pancreatic cancer progression. Pancreas (2014) 0.85
Complexin is able to bind to SNARE core complexes in different assembled states with distinct affinity. Biochem Biophys Res Commun (2006) 0.85
Human umbilical cord mesenchymal stem cells inhibit C6 glioma growth via secretion of dickkopf-1 (DKK1). Mol Cell Biochem (2013) 0.84
Yellow-light generation of 5.7 W by intracavity doubling self-Raman laser of YVO(4)/Nd:YVO(4) composite. Opt Lett (2009) 0.84
Phase I trial of non-cytotoxic suramin as a modulator of docetaxel and gemcitabine therapy in previously treated patients with non-small cell lung cancer. Cancer Chemother Pharmacol (2010) 0.83
Identification of two novel HLA-A*0201-restricted CTL epitopes derived from MAGE-A4. Clin Dev Immunol (2011) 0.83
Protein kinase A-mediated cardioprotection of Tongxinluo relates to the inhibition of myocardial inflammation, apoptosis, and edema in reperfused swine hearts. Chin Med J (Engl) (2013) 0.83
Detection of a common chimeric transcript between human chromosomes 7 and 16. Biol Direct (2012) 0.83
Liver X receptor agonist treatment promotes the migration of granule neurons during cerebellar development. J Neurochem (2010) 0.83
The microRNA expression profiles of mouse mesenchymal stem cell during chondrogenic differentiation. BMB Rep (2011) 0.82
Clinical features and linkage analysis for a Chinese family with autosomal dominant central areolar choroidal dystrophy. Chin Med J (Engl) (2009) 0.82
Immunohistochemical localization of sortilin and p75(NTR) in normal and ischemic rat retina. Neurosci Lett (2009) 0.82
FSCB phosphorylation in mouse spermatozoa capacitation. BMB Rep (2011) 0.82
Inhibition of the expression of TGF-β1 and CTGF in human mesangial cells by exendin-4, a glucagon-like peptide-1 receptor agonist. Cell Physiol Biochem (2012) 0.82
Effects of urate-lowering therapy in hyperuricemia on slowing the progression of renal function: a meta-analysis. J Ren Nutr (2012) 0.82
Second-order surface-plasmon assisted responsivity enhancement in germanium nano-photodetectors with bull's eye antennas. Opt Express (2014) 0.81
Differential regulation of survivin by p53 contributes to cell cycle dependent apoptosis. Cell Res (2005) 0.81
p53 controls hepatitis C virus non-structural protein 5A-mediated downregulation of GADD45α expression via the NF-κB and PI3K-Akt pathways. J Gen Virol (2012) 0.81
Construction vascular-specific expression bi-directional promoters in plants. J Biotechnol (2009) 0.81
Quantitative image analysis of intra-tumoral bFGF level as a molecular marker of paclitaxel resistance. J Transl Med (2008) 0.80
Season- and age-associated telomerase activity in Ginkgo biloba L. Mol Biol Rep (2010) 0.80
Wharton's Jelly Transplantation Improves Neurologic Function in a Rat Model of Traumatic Brain Injury. Cell Mol Neurobiol (2015) 0.80
Effect of thymosin alpha-1 on subpopulations of Th1, Th2, Th17, and regulatory T cells (Tregs) in vitro. Braz J Med Biol Res (2011) 0.80
Comparative outcomes of the tubularized incised plate and transverse island flap onlay techniques for the repair of proximal hypospadias. Int Urol Nephrol (2013) 0.80
Upregulation of Talin-1 expression associates with advanced pathological features and predicts lymph node metastases and biochemical recurrence of prostate cancer. Medicine (Baltimore) (2016) 0.80
Comparative analysis of telomeric restriction fragment lengths in different tissues of Ginkgo biloba trees of different age. J Plant Res (2007) 0.80
Identification of interacting proteins of retinoid-related orphan nuclear receptor gamma in HepG2 cells. BMB Rep (2012) 0.80
Expressions of eNOS3 and Ve-cadherin in microvascular endothelium at 7-day of reperfused acute myocardial infarction. Cardiovasc Hematol Disord Drug Targets (2009) 0.80
Anisotropic growth-induced synthesis of dual-compartment Janus mesoporous silica nanoparticles for bimodal triggered drugs delivery. J Am Chem Soc (2014) 0.80
Surveillance for avian influenza A(H7N9), Beijing, China, 2013. Emerg Infect Dis (2013) 0.79
[Comparison of doxycycline, losartan, and their combination on the expression of matrix metalloproteinase, tissue inhibitor of matrix metalloproteinase, and collagen remodeling in the noninfarcted myocardium after acute myocardial infarction in rats]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao (2005) 0.79
Low-dose suramin enhanced paclitaxel activity in chemotherapy-naive and paclitaxel-pretreated human breast xenograft tumors. Clin Cancer Res (2004) 0.79
Functional differences between integrin alpha4 and integrins alpha5/alphav in modulating the motility of human oral squamous carcinoma cells in response to the V region and heparin-binding domain of fibronectin. Exp Cell Res (2004) 0.79
d-β-Hydroxybutyrate inhibited the apoptosis of PC12 cells induced by H2O2 via inhibiting oxidative stress. Neurochem Int (2012) 0.79
[Establishment and evaluation of acute pulmonary thromboembolism model in minipig]. Zhonghua Yi Xue Za Zhi (2012) 0.79
Identification of a new MAGE-A10 antigenic peptide presented by HLA-A*0201 on tumor cells. Cancer Biol Ther (2011) 0.79
Efficient third-harmonic generation based on Tamm plasmon polaritons. Opt Lett (2013) 0.78
A20 overexpression inhibits low shear flow-induced CD14-positive monocyte recruitment to endothelial cells. Biorheology (2009) 0.78
Aberrant ADAM10 expression correlates with osteosarcoma progression. Eur J Med Res (2014) 0.78
[Establishment of acute myocardial infarction model in diabetic miniature pigs through video-assisted thoracoscopic surgery]. Zhonghua Yi Xue Za Zhi (2013) 0.78
Molecular characterization of a glutathione transferase from Pinus tabulaeformis (Pinaceae). Biochimie (2005) 0.78
PET image reconstruction: a robust state space approach. Inf Process Med Imaging (2005) 0.78
Change of season-specific telomere lengths in Ginkgo biloba L. Mol Biol Rep (2009) 0.78
Construction of the subtracted cDNA library of striatal neurons treated with long-term morphine. Chin Med Sci J (2011) 0.78
Phosphorus availability changes chromium toxicity in the freshwater alga Chlorella vulgaris. Chemosphere (2013) 0.77
Sense-, antisense- and RNAi-4CL1 regulate soluble phenolic acids, cell wall components and growth in transgenic Populus tomentosa Carr. Plant Physiol Biochem (2013) 0.77
CYP1B1 Asn453Ser polymorphism and colorectal cancer risk: a meta-analysis. Metabolism (2012) 0.77
Histone methylation mediates plasticity of human FOXP3(+) regulatory T cells by modulating signature gene expressions. Immunology (2014) 0.77
The promotion of endothelial progenitor cells recruitment by nerve growth factors in tissue-engineered blood vessels. Biomaterials (2009) 0.77
Myocardium and microvessel endothelium apoptosis at day 7 following reperfused acute myocardial infarction. Microvasc Res (2009) 0.77
Isolation and characterisation of an HpSHP gene from Hosta plantaginea. Mol Biol Rep (2012) 0.77
[Beneficial effects of ischemic preconditioning on myocardial no-reflow in a mini-swine model of acute myocardial infarction and reperfusion]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao (2005) 0.77
Comparison of three doses of enalapril in preventing left ventricular remodeling after acute myocardial infarction in the rat. Chin Med J (Engl) (2002) 0.77
Clinical implications of the tumor-infiltrating lymphocyte subsets in colorectal cancer. Med Oncol (2013) 0.77
Design of a zinc finger protein binding a sequence upstream of the A20 gene. BMC Biotechnol (2008) 0.77
[Beneficial effects of adenosine on myocardial no-reflow in a mini-swine model of acute myocardial infarction and reperfusion]. Zhonghua Xin Xue Guan Bing Za Zhi (2005) 0.77
Levels and chiral signatures of organochlorine pesticides in urban soils of Yinchuan, China. Bull Environ Contam Toxicol (2009) 0.77
[Effect of butylphthalide on the expression of GFAP and VEGF in the hippocampus of rats with Alzheimer's disease]. Zhong Nan Da Xue Xue Bao Yi Xue Ban (2010) 0.76
Reduced FOXP3 expression causes IPEX syndrome onset: An implication from an IPEX patient and his disease-free twin brother. Clin Immunol (2010) 0.76
Absolute measurements and certified reference material for iron isotopes using multiple-collector inductively coupled mass spectrometry. Rapid Commun Mass Spectrom (2008) 0.76